What is the ticker symbol for Ionis Pharmaceuticals, Inc.?

The ticker symbol for Ionis Pharmaceuticals, Inc. is NASDAQ:IONS

Does Ionis Pharmaceuticals, Inc. pay dividends?

No, Ionis Pharmaceuticals, Inc. does not pay dividends

What sector is Ionis Pharmaceuticals, Inc. in?

Ionis Pharmaceuticals, Inc. is in the Healthcare sector

What industry is Ionis Pharmaceuticals, Inc. in?

Ionis Pharmaceuticals, Inc. is in the Biotechnology industry

What country is Ionis Pharmaceuticals, Inc. based in?

Ionis Pharmaceuticals, Inc. is headquartered in United States

When did Ionis Pharmaceuticals, Inc. go public?

Ionis Pharmaceuticals, Inc. initial public offering (IPO) was on May 17, 1991

Is Ionis Pharmaceuticals, Inc. in the S&P 500?

No, Ionis Pharmaceuticals, Inc. is not included in the S&P 500 index

Is Ionis Pharmaceuticals, Inc. in the NASDAQ 100?

No, Ionis Pharmaceuticals, Inc. is not included in the NASDAQ 100 index

Is Ionis Pharmaceuticals, Inc. in the Dow Jones?

No, Ionis Pharmaceuticals, Inc. is not included in the Dow Jones index

When was Ionis Pharmaceuticals, Inc. last earnings report?

Ionis Pharmaceuticals, Inc.'s most recent earnings report was on July 29, 2026

When does Ionis Pharmaceuticals, Inc. report earnings?

The next expected earnings date for Ionis Pharmaceuticals, Inc. is November 4, 2026

IONS Stock Financials, Chart, Sentiment & Profile

Summary

Current Price: As of today, IONS price is $44.44, down -4.94% on September 18, 2026
Current Price All-Time High: IONS price is currently -48.77% below its historical high of $86.74 set on February 5, 2026
Market Cap: IONS current market cap is $7B, down -24.86% year-over-year
Revenue: IONS current annual revenue is $943.71M, up +33.83% year-over-year
Next Earnings: The next earnings release for IONS is on November 4, 2026

Profile

Company profile for Ionis Pharmaceuticals, Inc. (IONS)
Metric	Value
Full Name	Ionis Pharmaceuticals, Inc.
Ticker	NASDAQ: IONS
Exchange	NASDAQ
Sector	Healthcare
Industry	Biotechnology
Country	United States
IPO	May 17, 1991
Indexes	Not included
Website	ionis.com
Employees	1,069

Key Metrics

Ionis Pharmaceuticals, Inc. Key Details
Metric	Value	Date
Price	$44.44	Sep 18, 26
Price, 1D Change	-4.94%	Sep 18, 26
Market Cap	$7B	Sep 18, 26
	-	Sep 18, 26
PE Ratio	-	Sep 18, 26
Beta	0.45	Sep 18, 26
Revenue	$943.71M	Dec 31, 25
Revenue, 1Y Change	+33.83%	Dec 31, 25
EPS	-$2.38	Dec 31, 25
EPS, 1Y Change	+21.49%	Dec 31, 25

Events

Ionis Pharmaceuticals, Inc. Events
Metric	Value	Date
Next Earnings		Nov 4, 26
Last Qtr. Earnings		Jul 29, 26
Last Ann. Earnings		Feb 25, 26
Last Ex-Dividend	N/A	N/A
Next Ex-Dividend	N/A	N/A
Last Split	N/A	N/A
Next Split	N/A	N/A
Last Ticker Change	ISIS	Jan 21, 16
Next Ticker Change	N/A	N/A

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Estimates

IONS Estimates
Metric	Value	Date
EPS	-$2.38	Dec 31, 25
EPS Estimate	-$2.70	N/A
EPS Est. Change	-13.37%	N/A
Revenue	$943.71M	Dec 31, 25
Revenue Estimate	$921.42M	N/A
Revenue Est. Change	-2.36%	N/A
Current Price	$44.44	Sep 18, 26
Price Target	$85.00	-
Price Tgt. Change	+91.27%	-

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EPS

IONS EPS reported versus estimate values
Year	Estimate	Reported	Surprise / Exp.
2024	-$2.54	-$3.04	-19.31%
2025	-$1.66	-$2.38	-43.17%
2026	-$2.70	N/A	-13.37%
2027	-$1.11	N/A	+53.33%

Revenue

IONS revenue reported versus estimate values chart
Year	Estimate	Reported	Surprise / Exp.
2024	$620.13M	$705.14M	+13.71%
2025	$897.47M	$943.71M	+5.15%
2026	$921.42M	N/A	-2.36%
2027	$1.38B	N/A	+46.03%

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Performance

IONS Performance
Metric	Value	Date
Price, 1Y	-28.02%	Sep 18, 26
Price, 3Y	+3.52%	Sep 18, 26
Market Cap, 1Y	-24.86%	Sep 18, 26
Market Cap, 3Y	+20.16%	Sep 18, 26
Revenue, 1Y	+33.83%	Dec 31, 25
Revenue, 3Y	+60.67%	Dec 31, 25
EPS, 1Y	+21.49%	Dec 31, 25
EPS, 3Y	-25.35%	Dec 31, 25

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Technicals

IONS Technical Indicators
Metric	Value	Date
Current Price	$44.44	Sep 18, 26
SMA 200	$72.18	Sep 18, 26
SMA 50	$55.97	Sep 18, 26
EMA 200	$65.44	Sep 18, 26
EMA 50	$58.29	Sep 18, 26
MACD	-$3.49	Sep 18, 26
Beta	0.45	Sep 18, 26
ATR	$2.50	Sep 18, 26
14-Day RSI	25.37	Sep 18, 26
10-Day Volatility	54.99%	Sep 18, 26

Dividends

IONS Dividends
Metric	Value	Date
	-	N/A
Upcoming	N/A	N/A
	-	Sep 18, 26
	-	Dec 31, 25
	$0.00	Dec 31, 25
	0.00%	Dec 31, 25

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Income & Profitability

IONS Income & Profitability
Metric	Value	Date
Revenue	$943.71M	Dec 31, 25
EPS	-$2.38	Dec 31, 25
Gross Profit	$928.00M	Dec 31, 25
Gross Margin	98.31%	Dec 31, 25
Operating Income	-$382.00M	Dec 31, 25
Operating Margin	-40.47%	Dec 31, 25
Net Income	-$381.39M	Dec 31, 25
Net Margin	-40.36%	Dec 31, 25
EBITDA	-$358.99M	Dec 31, 25

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Financial Health

IONS Financial Health
Metric	Value	Date
Debt To Equity	5.24	Dec 31, 25
	1.95	Dec 31, 25
	1.94	Dec 31, 25
	-	Dec 31, 25
	2	Jun 30, 26
	0.82	Sep 18, 26

Valuations

IONS Valuations
Metric	Value	Date
PE Ratio	-	Sep 18, 26
	8.45	Sep 18, 26
	16.79	Sep 18, 26
	-13.24	Sep 18, 26
	-	N/A

Balance Sheet

IONS Balance Sheet
Metric	Value	Date
Book Value	$489.09M	Dec 31, 25
	$2.68B	Dec 31, 25
	$3.52B	Dec 31, 25
	$2.99B	Dec 31, 25
	$3.03B	Dec 31, 25
	$1.53B	Dec 31, 25
Total Debt	$2.61B	Dec 31, 25
	$1.18B	Dec 31, 25
	$28.08M	Dec 31, 25

Expenses

IONS Expenses
Metric	Value	Date
	$1.33B	Dec 31, 25
	$1.31B	Dec 31, 25
	$28.36M	Dec 31, 25
	$0.00	Dec 31, 25
	$22.69M	Dec 31, 25
	$0.00	Dec 31, 25
	$1.79M	Dec 31, 25

Cash Flow

IONS Cash Flow
Metric	Value	Date
	-$268.58M	Dec 31, 25
	-$277.78M	Dec 31, 25
	$675.84M	Dec 31, 25
Capex	$57.08M	Dec 31, 25
	-$325.67M	Dec 31, 25

Recent analyst updates

IONS Recent analyst updates
Metric	Value	Date
Guggenheim	→	Sep 15, 26
Barclays	→	Sep 9, 26
Morgan Stanley	→	Sep 8, 26
HC Wainwright & Co.	→	Sep 8, 26
Goldman Sachs	→	Sep 8, 26
Canaccord Genuity	→	Sep 8, 26
BMO Capital	→	Sep 8, 26
Needham	→	Sep 4, 26
HC Wainwright & Co.	→	Sep 4, 26
BMO Capital	→	Sep 4, 26

Analyst sentiment

Institutional ownership

No data

Screeners with IONS

FAQ

What is the ticker symbol for Ionis Pharmaceuticals, Inc.?: The ticker symbol for Ionis Pharmaceuticals, Inc. is NASDAQ:IONS
Does Ionis Pharmaceuticals, Inc. pay dividends?: No, Ionis Pharmaceuticals, Inc. does not pay dividends
What sector is Ionis Pharmaceuticals, Inc. in?: Ionis Pharmaceuticals, Inc. is in the Healthcare sector
What industry is Ionis Pharmaceuticals, Inc. in?: Ionis Pharmaceuticals, Inc. is in the Biotechnology industry
What country is Ionis Pharmaceuticals, Inc. based in?: Ionis Pharmaceuticals, Inc. is headquartered in United States
When did Ionis Pharmaceuticals, Inc. go public?: Ionis Pharmaceuticals, Inc. initial public offering (IPO) was on May 17, 1991
Is Ionis Pharmaceuticals, Inc. in the S&P 500?: No, Ionis Pharmaceuticals, Inc. is not included in the S&P 500 index
Is Ionis Pharmaceuticals, Inc. in the NASDAQ 100?: No, Ionis Pharmaceuticals, Inc. is not included in the NASDAQ 100 index
Is Ionis Pharmaceuticals, Inc. in the Dow Jones?: No, Ionis Pharmaceuticals, Inc. is not included in the Dow Jones index
When was Ionis Pharmaceuticals, Inc. last earnings report?: Ionis Pharmaceuticals, Inc.'s most recent earnings report was on July 29, 2026
When does Ionis Pharmaceuticals, Inc. report earnings?: The next expected earnings date for Ionis Pharmaceuticals, Inc. is November 4, 2026

Data Sources & References

IONS Official Website www.ionis.com
Most Recent Annual Report (10-K) www.sec.gov/Archives/edgar/data/874015/000087401526000115/0000874015-26-000115-index.htm
IONS Profile on Yahoo Finance finance.yahoo.com/quote/IONS
IONS Profile on NASDAQ.com www.nasdaq.com/market-activity/stocks/ions