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Ionis Pharmaceuticals, Inc. (IONS)

Profile

Full Name

Ionis Pharmaceuticals, Inc.

Ticker

NASDAQ: IONS

Exchange

NASDAQ

Sector

Healthcare

Industry

Biotechnology

Country

United States

IPO

May 17, 1991

Indexes

Not included

Website

https://www.ionis.com

Employees

1069

Key Details

Price

$61.00(-0.38%)

Market cap

$9.72B(Mid cap)

Last Dividend

-

TTM Dividend yield

-

Annual revenue

$705.14M(-10.48% YoY)

Annual EPS

-$3.04(-18.75% YoY)

PE ratio

-

Next earnings date

Nov 5, 2025

Next ex-dividend date

N/A

Next split date

N/A

Quick Search

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    Analyst ratings

    Price

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    Current Price

    $61.00
    IONS price is $61.00

    30-Day Relative Volume

    0.84
    IONS 30-day relative volume is 0.84

    Price Performance

    Price Today change

    -0.38%
    IONS price is down -0.38% today

    Price YTD change

    +74.49%
    IONS price is up +74.49% since January 1st

    Price 1-year change

    +30.09%
    IONS price is up +30.09% year-on-year

    Price 3-year change

    +37.79%
    IONS price is up +37.79% over the past 3 years

    Price Range

    Price All-time high

    $86.58
    IONS price is currently -29.54% below its historical high of $86.58

    Price 3-year low

    $23.95
    IONS price is currently +154.70% above its 3-year low

    Capitalization

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    Market cap

    Market cap

    $9.72B
    IONS market capitalization is $9.72 billion

    Market cap 3-year change

    +54.73%
    IONS market capitalization is up +54.73% over the past 3 years

    Market cap All-time high

    $12.04B
    IONS market capitalization is currently -19.24% below its historical high of $12.04 billion

    Market cap sector rank

    91.86%
    IONS market capitalization is higher than 91.86% of companies in Healthcare sector

    Shares Outstanding

    Shares Outstanding 1-Year Change

    +9.01%
    IONS shares outstanding is up +9.01% year-on-year

    Shares Outstanding 3-Year Change

    +12.29%
    IONS shares outstanding is up +12.29% over the past 3 years

    Technical Indicators

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    Beta

    0.79
    IONS beta is 0.79

    200-day SMA

    $35.98
    IONS price is currently +69.54% above its 200-day simple moving average

    50-day SMA

    $43.95
    IONS price is currently +38.79% above its 50-day simple moving average

    RSI

    82.56
    IONS 14-day relative strength index is 82.56

    Volume

    0.84
    IONS 30-day relative volume is 0.84

    ATR

    $2.39
    IONS average true range is $2.39

    10-day Historical Volatility

    175.00%
    IONS 10-day historical volatility is 175.00%

    Dividend

    Income Statement

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    Revenue

    Revenue

    $705.14M
    IONS annual revenue is $705.14 million

    Revenue Analysts estimate

    $867.81M
    IONS annual revenue is currently -18.74% lower than the consensus analysts' forecast

    Revenue 1-year change

    -10.48%
    IONS annual revenue is down -10.48% year-on-year

    Revenue Sector rank

    83.69%
    IONS annual revenue is higher than 83.69% of companies in Healthcare sector

    EPS

    EPS

    -$3.04
    IONS annual earnings per share is -$3.04

    EPS Analysts estimate

    -$1.89
    IONS annual earnings per share is currently +60.71% higher than the consensus analysts' forecast

    EPS 1-year change

    -18.75%
    IONS annual earnings per share is down -18.75% year-on-year

    EPS Sector rank

    28.4%
    IONS annual earnings per share is higher than 28.4% of companies in Healthcare sector

    Profit

    Gross profit

    $671.93M
    IONS annual gross profit is $671.93 million

    Gross margin

    95.29%
    IONS annual gross profit margin is 95.29%

    Operating profit

    -$475.11M
    IONS annual operating income is -$475.11 million

    Operating margin

    -67.38%
    IONS annual operating profit margin is -67.38%

    Net income

    -$453.90M
    IONS annual net profit is -$453.90 million

    Net margin

    -64.37%
    IONS annual net profit margin is -64.37%

    Expenses

    Total expenses

    $1.18B
    IONS annual total expenses is $1.18 billion

    Operating expenses

    $1.17B
    IONS annual total operating expenses is $1.17 billion

    Cost of goods sold

    $33.20M
    IONS annual cost of goods sold is $33.20 million

    Selling, general & administrative expenses

    $267.50M
    IONS annual SGA is $267.50 million

    Depreciation and amortization

    $21.99M
    IONS annual depreciation & amortization is $21.99 million

    Interest expense

    $0.00
    IONS annual interest expense is $0.00

    Income tax

    -$6.17M
    IONS annual income tax is -$6.17 million

    EBIT & EBITDA

    EBIT

    -$375.71M
    IONS annual earnings before interest & taxes is -$375.71 million

    EBITDA

    -$353.72M
    IONS annual EBITDA is -$353.72 million

    Balance Sheet

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    Assets

    Total assets

    $3.00B
    IONS annual total assets is $3.00 billion

    Non current assets

    $383.38M
    IONS annual long term assets is $383.38 million

    Current assets

    $2.62B
    IONS annual total current assets is $2.62 billion

    Cash and cash equivalents

    $242.08M
    IONS annual cash & cash equivalents is $242.08 million

    Accounts receivable

    $92.19M
    IONS annual accounts receivable is $92.19 million

    Inventory

    $12.51M
    IONS annual inventory is $12.51 million

    Liabilities

    Total liabilities

    $2.42B
    IONS annual total liabilities is $2.42 billion

    Long term liabilities

    $2.11B
    IONS annual total long term liabilities is $2.11 billion

    Current liabilities

    $309.32M
    IONS annual total current liabilities is $309.32 million

    Accounts payable

    $42.96M
    IONS annual accounts payable is $42.96 million

    Debt

    Total debt

    $1.96B
    IONS annual total debt is $1.96 billion

    Total debt 1-year change

    -0.43%
    IONS annual total debt is down -0.43% year-on-year

    Long term debt

    $1.41B
    IONS annual long term debt is $1.41 billion

    Short term debt

    $9.28M
    IONS annual short term debt is $9.28 million

    Equity & Capital

    Shareholders equity

    $588.35M
    IONS annual stockholders equity is $588.35 million

    Book value

    $588.35M
    IONS annual book value is $588.35 million

    Retained earnings

    -$2.25B
    IONS annual retained earnings is -$2.25 billion

    Working capital

    $2.31B
    IONS annual working capital is $2.31 billion

    Cash Flow Statement

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    Cashflow Activities

    Cash from operations

    -$500.95M
    IONS annual cash flow from operations is -$500.95 million

    Cash from operations 1-year change

    -62.9%
    IONS annual cash flow from operations is down -62.9% year-on-year

    Cash from investing

    -$134.03M
    IONS annual cash flow from investing activities is -$134.03 million

    Cash from investing 1-year change

    +37.41%
    IONS annual cash flow from investing activities is up +37.41% year-on-year

    Cash from financing

    $478.06M
    IONS annual cash flow from financing activities is $478.06 million

    Cash from financing 1-year change

    -25.78%
    IONS annual cash flow from financing activities is down -25.78% year-on-year

    CAPEX

    CAPEX

    $50.34M
    IONS annual capital expenditures is $50.34 million

    CAPEX 1-year change

    +79.72%
    IONS annual capital expenditures is up +79.72% year-on-year

    Free Cash Flow

    Free cash flow

    -$551.29M
    IONS annual free cash flow is -$551.29 million

    Free cash flow 1-year change

    -64.31%
    IONS annual free cash flow is down -64.31% year-on-year

    Profitability Ratios

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    Margins

    Gross margin

    95.29%
    IONS annual gross profit margin is 95.29%

    Operating margin

    -67.38%
    IONS annual operating profit margin is -67.38%

    Net margin

    -64.37%
    IONS annual net profit margin is -64.37%

    ROA & ROE

    ROA

    -15.15%
    IONS annual return on assets is -15.15%

    ROE

    -93.10%
    IONS annual return on equity is -93.10%

    Valuation

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    PE Ratio

    PE ratio

    -
    IONS price to earnings ratio value is unknown

    PE ratio Sector rank

    -
    IONS price to earnings ratio is unknown

    PB Ratio

    PB ratio

    15.39
    IONS price to book ratio is 15.39

    PB ratio Sector rank

    92.85%
    IONS price to book ratio is higher than 92.85% of companies in Healthcare sector

    PS Ratio

    PS ratio

    10.29
    IONS price to sales ratio is 10.29

    PS ratio Sector rank

    73.7%
    IONS price to sales ratio is higher than 73.7% of companies in Healthcare sector

    Enterprise value

    Enterprise value

    $9.40B
    IONS enterprise value is $9.40 billion

    Enterprise value Sector rank

    91.05%
    IONS enterprise value is higher than 91.05% of companies in Healthcare sector

    EV/EBITDA

    EV/EBITDA

    -56.10
    IONS EV/EBITDA is -56.10

    EV/EBITDA Sector rank

    2.42%
    IONS EV/EBITDA is higher than 2.42% of companies in Healthcare sector

    Financial Health

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    Liquidity

    Current ratio

    8.47
    IONS annual current ratio is 8.47

    Quick ratio

    8.43
    IONS annual quick ratio is 8.43

    Leverage

    Debt to equity

    2.13
    IONS annual debt to equity ratio is 2.13

    Interest coverage ratio

    -
    IONS annual interest coverage ratio value is unknown

    Risk & Stability

    Piotroski F-Score

    4
    IONS piotroski f-score is 4

    Altman Z-Score

    2.11
    IONS altman z-score is 2.11

    Analyst ratings

    Recent major analysts updates

    Sep 4, 25 RBC Capital
    Outperform
    Sep 3, 25 Goldman Sachs
    Sell
    Sep 3, 25 Citigroup
    Buy
    Sep 3, 25 Barclays
    Overweight
    Sep 3, 25 BMO Capital
    Outperform
    Sep 2, 25 Needham
    Buy
    Sep 2, 25 Jefferies
    Buy
    Sep 2, 25 HC Wainwright & Co.
    Buy
    Aug 25, 25 Needham
    Buy
    Aug 25, 25 JP Morgan
    Neutral

    Institutional Ownership

    Screeners with IONS included

    Growing Shares Outstanding
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    Healthcare sector
    • What is the ticker symbol for Ionis Pharmaceuticals, Inc.?
    • Does Ionis Pharmaceuticals, Inc. pay dividends?
    • What sector is Ionis Pharmaceuticals, Inc. in?
    • What industry is Ionis Pharmaceuticals, Inc. in?
    • What country is Ionis Pharmaceuticals, Inc. based in?
    • When did Ionis Pharmaceuticals, Inc. go public?
    • Is Ionis Pharmaceuticals, Inc. in the S&P 500?
    • Is Ionis Pharmaceuticals, Inc. in the NASDAQ 100?
    • Is Ionis Pharmaceuticals, Inc. in the Dow Jones?
    • When was Ionis Pharmaceuticals, Inc.'s last earnings report?
    • When does Ionis Pharmaceuticals, Inc. report earnings?

    What is the ticker symbol for Ionis Pharmaceuticals, Inc.?

    The ticker symbol for Ionis Pharmaceuticals, Inc. is NASDAQ:IONS

    Does Ionis Pharmaceuticals, Inc. pay dividends?

    No, Ionis Pharmaceuticals, Inc. does not pay dividends

    What sector is Ionis Pharmaceuticals, Inc. in?

    Ionis Pharmaceuticals, Inc. is in the Healthcare sector

    What industry is Ionis Pharmaceuticals, Inc. in?

    Ionis Pharmaceuticals, Inc. is in the Biotechnology industry

    What country is Ionis Pharmaceuticals, Inc. based in?

    Ionis Pharmaceuticals, Inc. is headquartered in United States

    When did Ionis Pharmaceuticals, Inc. go public?

    Ionis Pharmaceuticals, Inc.'s initial public offering (IPO) was on May 17, 1991

    Is Ionis Pharmaceuticals, Inc. in the S&P 500?

    No, Ionis Pharmaceuticals, Inc. is not included in the S&P 500 index

    Is Ionis Pharmaceuticals, Inc. in the NASDAQ 100?

    No, Ionis Pharmaceuticals, Inc. is not included in the NASDAQ 100 index

    Is Ionis Pharmaceuticals, Inc. in the Dow Jones?

    No, Ionis Pharmaceuticals, Inc. is not included in the Dow Jones index

    When was Ionis Pharmaceuticals, Inc.'s last earnings report?

    Ionis Pharmaceuticals, Inc.'s most recent earnings report was on July 30, 2025

    When does Ionis Pharmaceuticals, Inc. report earnings?

    The next expected earnings date for Ionis Pharmaceuticals, Inc. is November 5, 2025
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