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Ionis Pharmaceuticals, Inc. (IONS) Gross margin

annual gross margin:

95.29%-0.69%(-0.72%)
December 31, 2024

Summary

  • As of today (August 20, 2025), IONS annual gross profit margin is 95.29%, with the most recent change of -0.69% (-0.72%) on December 31, 2024.
  • During the last 3 years, IONS annual gross margin has fallen by -0.96% (-1.00%).
  • IONS annual gross margin is now -3.14% below its all-time high of 98.38%, reached on December 31, 2017.

Performance

IONS Gross margin Chart

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Highlights

Range

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OtherIONSprofitability metrics

quarterly gross margin:

98.45%+3.66%(+3.86%)
June 30, 2025

Summary

  • As of today (August 20, 2025), IONS quarterly gross profit margin is 98.45%, with the most recent change of +3.66% (+3.86%) on June 30, 2025.
  • Over the past year, IONS quarterly gross margin has increased by +2.78% (+2.91%).
  • IONS quarterly gross margin is now -96.86% below its all-time high of 3133.33%, reached on December 31, 1992.

Performance

IONS quarterly gross margin Chart

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Gross margin Formula

Gross Margin =  Gross Profit
Revenue
✕ 100%

IONS Gross margin Trends

PeriodPeriodAnnualAnnualQuarterlyQuarterly
1 y1 year-0.7%+2.9%
3 y3 years-1.0%+6.3%
5 y5 years-2.9%+3.5%

IONS Gross margin Highs & Lows

PeriodPeriodAnnual vs highAnnual vs highAnnual vs lowAnnual vs lowQuarter. vs highQuarter. vs highQuarter. vs lowQuarter. vs low
3 y3-year-1.0%+1.6%at high+6.3%
5 y5-year-2.9%+1.6%at high+6.3%
alltimeall time-3.1%+179.4%-96.9%+123.9%

IONS Gross margin History

DateAnnualQuarterly
Jun 2025
-
98.45%(+3.9%)
Mar 2025
-
94.79%(-1.2%)
Dec 2024
95.29%(-0.7%)
95.92%(+0.9%)
Sep 2024
-
95.09%(-0.6%)
Jun 2024
-
95.67%(+2.4%)
Mar 2024
-
93.47%(-4.0%)
Dec 2023
95.98%(+2.3%)
97.35%(+2.9%)
Sep 2023
-
94.60%(-1.1%)
Jun 2023
-
95.63%(+1.0%)
Mar 2023
-
94.68%(+2.1%)
Dec 2022
93.83%(-2.5%)
92.74%(-3.3%)
Sep 2022
-
95.86%(+3.5%)
Jun 2022
-
92.65%(-1.0%)
Mar 2022
-
93.61%(-4.9%)
Dec 2021
96.25%(+0.2%)
98.41%(+4.5%)
Sep 2021
-
94.15%(+0.5%)
Jun 2021
-
93.66%(+0.3%)
Mar 2021
-
93.34%(-4.2%)
Dec 2020
96.01%(-2.2%)
97.39%(+2.2%)
Sep 2020
-
95.29%(+0.1%)
Jun 2020
-
95.16%(+0.2%)
Mar 2020
-
95.01%(-4.0%)
Dec 2019
98.18%(+0.6%)
98.97%(+1.8%)
Sep 2019
-
97.23%(+0.3%)
Jun 2019
-
96.93%(-1.6%)
Mar 2019
-
98.46%(+0.7%)
Dec 2018
97.61%(-0.8%)
97.76%(>+9900.0%)
Sep 2018
-
0.00%(0.0%)
Jun 2018
-
0.00%(0.0%)
Mar 2018
-
0.00%(-100.0%)
Dec 2017
98.38%(>+9900.0%)
99.41%(>+9900.0%)
Sep 2017
-
0.00%(0.0%)
Jun 2017
-
0.00%(0.0%)
Mar 2017
-
0.00%(0.0%)
Dec 2016
0.00%(0.0%)
0.00%(0.0%)
Sep 2016
-
0.00%(0.0%)
Jun 2016
-
0.00%(0.0%)
Mar 2016
-
0.00%(0.0%)
Dec 2015
0.00%(0.0%)
0.00%(0.0%)
Sep 2015
-
0.00%(0.0%)
Jun 2015
-
0.00%(0.0%)
Mar 2015
-
0.00%(0.0%)
Dec 2014
0.00%(0.0%)
0.00%(0.0%)
Sep 2014
-
0.00%(0.0%)
Jun 2014
-
0.00%(0.0%)
Mar 2014
-
0.00%(0.0%)
Dec 2013
0.00%(0.0%)
0.00%(0.0%)
Sep 2013
-
0.00%(0.0%)
Jun 2013
-
0.00%(0.0%)
Mar 2013
-
0.00%(0.0%)
Dec 2012
0.00%(0.0%)
0.00%(0.0%)
Sep 2012
-
0.00%(0.0%)
Jun 2012
-
0.00%(0.0%)
Mar 2012
-
0.00%(-100.0%)
Dec 2011
0.00%(0.0%)
-42.59%(-53.9%)
Sep 2011
-
-92.35%(+104.9%)
Jun 2011
-
-45.06%(-23.9%)
Mar 2011
-
-59.19%(<-9900.0%)
Dec 2010
0.00%(0.0%)
0.00%(0.0%)
Sep 2010
-
0.00%(0.0%)
Jun 2010
-
0.00%(0.0%)
Mar 2010
-
0.00%(0.0%)
DateAnnualQuarterly
Dec 2009
0.00%(0.0%)
0.00%(0.0%)
Sep 2009
-
0.00%(0.0%)
Jun 2009
-
0.00%(0.0%)
Mar 2009
-
0.00%(0.0%)
Dec 2008
0.00%(0.0%)
0.00%(0.0%)
Sep 2008
-
0.00%(0.0%)
Jun 2008
-
0.00%(0.0%)
Mar 2008
-
0.00%(0.0%)
Dec 2007
0.00%(0.0%)
0.00%(0.0%)
Sep 2007
-
0.00%(0.0%)
Jun 2007
-
0.00%(0.0%)
Mar 2007
-
0.00%(0.0%)
Dec 2006
0.00%(0.0%)
0.00%(0.0%)
Sep 2006
-
0.00%(0.0%)
Jun 2006
-
0.00%(0.0%)
Mar 2006
-
0.00%(0.0%)
Dec 2005
0.00%(0.0%)
0.00%(0.0%)
Sep 2005
-
0.00%(0.0%)
Jun 2005
-
0.00%(0.0%)
Mar 2005
-
0.00%(0.0%)
Dec 2004
0.00%(0.0%)
0.00%(0.0%)
Sep 2004
-
0.00%(0.0%)
Jun 2004
-
0.00%(0.0%)
Mar 2004
-
0.00%(0.0%)
Dec 2003
0.00%(0.0%)
0.00%(0.0%)
Sep 2003
-
0.00%(0.0%)
Jun 2003
-
0.00%(0.0%)
Mar 2003
-
0.00%(0.0%)
Dec 2002
0.00%(0.0%)
0.00%(0.0%)
Sep 2002
-
0.00%(0.0%)
Jun 2002
-
0.00%(0.0%)
Mar 2002
-
0.00%(0.0%)
Dec 2001
0.00%(0.0%)
0.00%(0.0%)
Sep 2001
-
0.00%(0.0%)
Jun 2001
-
0.00%(0.0%)
Mar 2001
-
0.00%(0.0%)
Dec 2000
0.00%(0.0%)
0.00%(0.0%)
Sep 2000
-
0.00%(0.0%)
Jun 2000
-
0.00%(0.0%)
Mar 2000
-
0.00%(0.0%)
Dec 1999
0.00%(0.0%)
0.00%(0.0%)
Sep 1999
-
0.00%(0.0%)
Jun 1999
-
0.00%(0.0%)
Mar 1999
-
0.00%(0.0%)
Dec 1998
0.00%(0.0%)
0.00%(0.0%)
Sep 1998
-
0.00%(0.0%)
Jun 1998
-
0.00%(0.0%)
Mar 1998
-
0.00%(-100.0%)
Dec 1997
0.00%(0.0%)
-
Dec 1996
0.00%(0.0%)
-
Dec 1995
0.00%(0.0%)
-
Dec 1994
0.00%(0.0%)
-
Dec 1993
0.00%(0.0%)
-
Dec 1992
0.00%(0.0%)
3133.33%(-3546.6%)
Sep 1992
-
-90.91%(-9.1%)
Jun 1992
-
-100.00%(-16.7%)
Mar 1992
-
-120.00%(-70.9%)
Dec 1991
0.00%(-100.0%)
-412.50%(+587.5%)
Sep 1991
-
-60.00%(-152.9%)
Jun 1991
-
113.33%(-524.9%)
Mar 1991
-
-26.67%
Dec 1990
-120.00%
-

FAQ

  • What is Ionis Pharmaceuticals, Inc. annual gross profit margin?
  • What is the all time high annual gross margin for Ionis Pharmaceuticals, Inc.?
  • What is Ionis Pharmaceuticals, Inc. annual gross margin year-on-year change?
  • What is Ionis Pharmaceuticals, Inc. quarterly gross profit margin?
  • What is the all time high quarterly gross margin for Ionis Pharmaceuticals, Inc.?
  • What is Ionis Pharmaceuticals, Inc. quarterly gross margin year-on-year change?

What is Ionis Pharmaceuticals, Inc. annual gross profit margin?

The current annual gross margin of IONS is 95.29%

What is the all time high annual gross margin for Ionis Pharmaceuticals, Inc.?

Ionis Pharmaceuticals, Inc. all-time high annual gross profit margin is 98.38%

What is Ionis Pharmaceuticals, Inc. annual gross margin year-on-year change?

Over the past year, IONS annual gross profit margin has changed by -0.69% (-0.72%)

What is Ionis Pharmaceuticals, Inc. quarterly gross profit margin?

The current quarterly gross margin of IONS is 98.45%

What is the all time high quarterly gross margin for Ionis Pharmaceuticals, Inc.?

Ionis Pharmaceuticals, Inc. all-time high quarterly gross profit margin is 3133.33%

What is Ionis Pharmaceuticals, Inc. quarterly gross margin year-on-year change?

Over the past year, IONS quarterly gross profit margin has changed by +2.78% (+2.91%)
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