Annual Gross Margin
95.29%0.69%-0.72%
Summary
- Current Value
- As of today, IONS annual gross margin is 95.29%, down -0.72% on
- Historical Performance
- IONS annual gross margin is down -1.00% over the past 3 years, and down -2.94% over the past 5 years
- All-Time High Comparison
- IONS annual gross margin is currently -3.14% below its historical high of 98.38% set on
- 3-Year Low Comparison
- IONS annual gross margin is +1.56% above its 3-year low of 93.83% reached on an earlier date
- Sector Comparison
- IONS annual gross margin is higher than 92.61% of companies in Healthcare sector
Gross Margin Chart
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Series
SUGGESTED SERIES
Performance
| Metric | Date | Value | 1Y | 3Y | 5Y | 15Y |
|---|---|---|---|---|---|---|
| Annual Gross Margin | 95.29% | -0.7% | -1.0% | -2.9% | +100.0% | |
| Quarterly Gross Margin | 96.67% | +1.7% | +0.8% | +1.4% | +100.0% | |
| Price | $79.48 | +127.5% | +99.5% | +33.2% | +700.4% | |
| PE Ratio | - | – | – | – | – | |
| Annual Revenue | $705.14M | -10.5% | -13.0% | -37.2% | +479.9% | |
| Annual Gross Profit | $671.93M | -11.1% | -13.9% | -39.0% | +100.0% | |
| Annual Operating Margin | -67.38% | -50.0% | -3602.2% | -306.8% | -197.5% | |
| Annual Net Margin | -64.37% | -38.4% | -1723.5% | -336.4% | -123.9% |
Gross Margin Highs
| Period | High | Date | Current |
|---|---|---|---|
| 3Y | 95.98% | -0.7% | |
| 5Y | 96.25% | -1.0% | |
| All | 98.38% | -3.1% |
Gross Margin Lows
| Period | Low | Date | Current |
|---|---|---|---|
| 3Y | 93.83% | N/A | +1.6% |
| 5Y | 93.83% | +1.6% | |
| All | -120.00% | +179.4% |
Gross Margin History
FAQ
What is the current annual gross margin of IONS?
As of today, IONS annual gross margin is 95.29%
What is 1-year change in IONS annual gross margin?
IONS annual gross margin is down -0.72% year-over-year
What is 3-year change in IONS annual gross margin?
IONS annual gross margin is down -1.00% over the past 3 years
How far is IONS annual gross margin from its all-time high?
IONS annual gross margin is currently -3.14% below its historical high of 98.38% set on December 31, 2017
How does IONS annual gross margin rank versus sector peers?
IONS annual gross margin is higher than 92.61% of companies in Healthcare sector
When is IONS next annual earnings release?
The next annual earnings release for IONS is on
Quarterly Gross Margin
96.67%1.78%-1.81%
Summary
- Current Value
- As of today, IONS quarterly gross margin is 96.67%, down -1.81% on
- Historical Performance
- IONS quarterly gross margin is up +1.66% year-over-year, and up +0.84% over the past 3 years
- All-Time High Comparison
- IONS quarterly gross margin is currently -96.91% below its historical high of 3,133.33% set on
- 3-Year Low Comparison
- IONS quarterly gross margin is +4.24% above its 3-year low of 92.74% reached on an earlier date
- Sector Comparison
- IONS quarterly gross margin is higher than 94.83% of companies in Healthcare sector
Performance
| Metric | Date | Value | 3M | 1Y | 3Y | 5Y |
|---|---|---|---|---|---|---|
| Quarterly Gross Margin | 96.67% | -1.8% | +1.7% | +0.8% | +1.4% | |
| Annual Gross Margin | 95.29% | – | -0.7% | -1.0% | -2.9% | |
| Price | $79.48 | +12.6% | +127.5% | +99.5% | +33.2% | |
| PE Ratio | - | – | – | – | – | |
| Quarterly Revenue | $156.72M | -65.3% | +17.1% | -1.9% | -2.1% | |
| Quarterly Gross Profit | $151.51M | -66.0% | +19.1% | -1.1% | -0.7% | |
| Quarterly Operating Margin | -102.21% | -430.5% | +8.0% | -176.0% | -347.9% | |
| Quarterly Net Margin | -82.06% | -400.3% | +21.8% | -179.0% | -258.8% |
Quarterly Gross Margin Highs
| Period | High | Date | Current |
|---|---|---|---|
| 1Y | 98.45% | -1.8% | |
| 3Y | 98.45% | -1.8% | |
| 5Y | 98.45% | -1.8% | |
| All | 3,133.33% | -96.9% |
Quarterly Gross Margin Lows
| Period | Low | Date | Current |
|---|---|---|---|
| 1Y | 94.79% | +2.0% | |
| 3Y | 92.74% | N/A | +4.2% |
| 5Y | 92.65% | +4.3% | |
| All | -412.50% | +123.4% |
Quarterly Gross Margin History
FAQ
What is the current quarterly gross margin of IONS?
As of today, IONS quarterly gross margin is 96.67%
What is IONS quarterly gross margin most recent change?
IONS quarterly gross margin was down -1.81% on September 1, 2025
What is 1-year change in IONS quarterly gross margin?
IONS quarterly gross margin is up +1.66% year-over-year
How far is IONS quarterly gross margin from its all-time high?
IONS quarterly gross margin is currently -96.91% below its historical high of 3,133.33% set on December 31, 1992
How does IONS quarterly gross margin rank versus sector peers?
IONS quarterly gross margin is higher than 94.83% of companies in Healthcare sector
When is IONS next earnings release?
The next earnings release for IONS is on
Gross Margin Formula
Gross Margin = Gross Profit
Revenue × 100%
Revenue × 100%
Data Sources & References
- IONS Official Website www.ionis.com
- Most Recent Annual Report (10-K) www.sec.gov/Archives/edgar/data/874015/000087401525000089/0000874015-25-000089-index.htm
- IONS Profile on Yahoo Finance finance.yahoo.com/quote/IONS
- IONS Profile on NASDAQ.com www.nasdaq.com/market-activity/stocks/ions