annual net margin:
-64.37%-17.87%(-38.43%)Summary
- As of today (August 20, 2025), IONS annual net profit margin is -64.37%, with the most recent change of -17.87% (-38.43%) on December 31, 2024.
- During the last 3 years, IONS annual net margin has fallen by -60.84% (-1723.51%).
- IONS annual net margin is now -276.99% below its all-time high of 36.37%, reached on December 31, 2018.
Performance
IONS Net margin Chart
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Range
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Quarterly net margin:
27.33%+138.97%(+124.48%)Summary
- As of today (August 20, 2025), IONS quarterly net profit margin is 27.33%, with the most recent change of +138.97% (+124.48%) on June 30, 2025.
- Over the past year, IONS quarterly net margin has increased by +56.75% (+192.90%).
- IONS quarterly net margin is now -47.23% below its all-time high of 51.79%, reached on September 30, 2007.
Performance
IONS Quarterly net margin Chart
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Net margin Formula
Net Margin = Net Income
Revenue ✕ 100%
Revenue ✕ 100%
IONS Net margin Trends
| PeriodPeriod | AnnualAnnual | QuarterlyQuarterly |
|---|---|---|
| 1 y1 year | -38.4% | +192.9% |
| 3 y3 years | -1723.5% | +134.8% |
| 5 y5 years | -336.4% | +255.2% |
IONS Net margin Highs & Lows
| PeriodPeriod | Annual vs highAnnual vs high | Annual vs lowAnnual vs low | Quarter. vs highQuarter. vs high | Quarter. vs lowQuarter. vs low | |
|---|---|---|---|---|---|
| 3 y | 3-year | -1723.5% | at low | at high | +122.9% |
| 5 y | 5-year | -336.4% | +2.1% | -46.5% | +122.4% |
| alltime | all time | -277.0% | +80.8% | -47.2% | +103.1% |
IONS Net margin History
| Date | Annual | Quarterly |
|---|---|---|
| Jun 2025 | - | 27.33%(-124.5%) |
| Mar 2025 | - | -111.64%(+142.4%) |
| Dec 2024 | -64.37%(+38.4%) | -46.05%(-56.1%) |
| Sep 2024 | - | -104.98%(+256.8%) |
| Jun 2024 | - | -29.42%(-75.4%) |
| Mar 2024 | - | -119.50%(+4093.0%) |
| Dec 2023 | -46.50%(+1.3%) | -2.85%(-97.2%) |
| Sep 2023 | - | -102.22%(+125.8%) |
| Jun 2023 | - | -45.27%(-52.5%) |
| Mar 2023 | - | -95.25%(+175.9%) |
| Dec 2022 | -45.92%(+1200.8%) | -34.52%(+17.4%) |
| Sep 2022 | - | -29.41%(-62.6%) |
| Jun 2022 | - | -78.58%(+71.1%) |
| Mar 2022 | - | -45.92%(-190.0%) |
| Dec 2021 | -3.53%(-94.6%) | 51.05%(-182.4%) |
| Sep 2021 | - | -61.96%(-3.7%) |
| Jun 2021 | - | -64.31%(-20.1%) |
| Mar 2021 | - | -80.52%(-34.1%) |
| Dec 2020 | -65.78%(-341.6%) | -122.13%(+699.3%) |
| Sep 2020 | - | -15.28%(-13.2%) |
| Jun 2020 | - | -17.61%(-40.7%) |
| Mar 2020 | - | -29.71%(-187.1%) |
| Dec 2019 | 27.23%(-25.1%) | 34.11%(+118.9%) |
| Sep 2019 | - | 15.58%(-3039.6%) |
| Jun 2019 | - | -0.53%(-101.9%) |
| Mar 2019 | - | 28.41%(-1004.8%) |
| Dec 2018 | 36.37%(+2340.9%) | - |
| Sep 2018 | - | -3.14%(-90.8%) |
| Jun 2018 | - | -34.27%(+3396.9%) |
| Mar 2018 | - | -0.98%(-43.7%) |
| Dec 2017 | 1.49%(-106.0%) | -1.74%(-21.3%) |
| Sep 2017 | - | -2.21%(-19.6%) |
| Jun 2017 | - | -2.75%(-135.5%) |
| Mar 2017 | - | 7.74%(-72.2%) |
| Dec 2016 | -24.97%(-19.8%) | 27.89%(+320.7%) |
| Sep 2016 | - | 6.63%(-104.5%) |
| Jun 2016 | - | -147.79%(-13.4%) |
| Mar 2016 | - | -170.63%(+23.2%) |
| Dec 2015 | -31.12%(+71.0%) | -138.52%(+90.2%) |
| Sep 2015 | - | -72.83%(-346.0%) |
| Jun 2015 | - | 29.60%(-210.8%) |
| Mar 2015 | - | -26.71%(-173.0%) |
| Dec 2014 | -18.20%(-55.8%) | 36.59%(-160.4%) |
| Sep 2014 | - | -60.54%(+186.0%) |
| Jun 2014 | - | -21.17%(-80.9%) |
| Mar 2014 | - | -111.08%(+93.3%) |
| Dec 2013 | -41.17%(-35.8%) | -57.46%(-44.8%) |
| Sep 2013 | - | -104.18%(+291.9%) |
| Jun 2013 | - | -26.58%(+588.6%) |
| Mar 2013 | - | -3.86%(-70.9%) |
| Dec 2012 | -64.16%(-25.0%) | -13.27%(-95.9%) |
| Sep 2012 | - | -324.45%(>+9900.0%) |
| Jun 2012 | - | -2.55%(-97.5%) |
| Mar 2012 | - | -103.27%(+67.0%) |
| Dec 2011 | -85.58%(+51.5%) | -61.83%(-52.4%) |
| Sep 2011 | - | -129.78%(+80.1%) |
| Jun 2011 | - | -72.07%(-23.8%) |
| Mar 2011 | - | -94.55%(+78.6%) |
| Dec 2010 | -56.47%(+96.4%) | -52.94%(+21.7%) |
| Sep 2010 | - | -43.51%(-59.3%) |
| Jun 2010 | - | -107.02%(+231.6%) |
| Mar 2010 | - | -32.27%(-38.2%) |
| Dec 2009 | -28.75%(+271.0%) | -52.20%(+20.7%) |
| Sep 2009 | - | -43.26%(+391.0%) |
| Jun 2009 | - | -8.81%(-74.5%) |
| Dec 2008 | -7.75%(-84.5%) | -34.61%(-732.7%) |
| Sep 2008 | - | 5.47%(-143.5%) |
| Jun 2008 | - | -12.58%(-60.1%) |
| Mar 2008 | - | -31.49%(-39.1%) |
| Dec 2007 | -49.96% | -51.72%(-199.9%) |
| Date | Annual | Quarterly |
|---|---|---|
| Sep 2007 | - | 51.79%(-117.9%) |
| Jun 2007 | - | -289.12%(-45.6%) |
| Mar 2007 | - | -531.43%(-14.6%) |
| Dec 2006 | -280.96%(+55.7%) | -622.62%(+67.3%) |
| Sep 2006 | - | -372.12%(+649.5%) |
| Jun 2006 | - | -49.65%(-85.9%) |
| Mar 2006 | - | -352.56%(+552.3%) |
| Dec 2005 | -180.40%(-46.0%) | -54.05%(-73.4%) |
| Sep 2005 | - | -203.43%(+9.6%) |
| Jun 2005 | - | -185.60%(-53.4%) |
| Mar 2005 | - | -398.52%(-21.1%) |
| Dec 2004 | -334.33%(+75.9%) | -505.40%(+40.5%) |
| Sep 2004 | - | -359.71%(+36.4%) |
| Jun 2004 | - | -263.63%(+23.3%) |
| Mar 2004 | - | -213.82%(-18.3%) |
| Dec 2003 | -190.03%(+110.9%) | -261.62%(+33.1%) |
| Sep 2003 | - | -196.59%(+27.8%) |
| Jun 2003 | - | -153.82%(-11.6%) |
| Mar 2003 | - | -173.98%(+140.3%) |
| Dec 2002 | -90.10%(-35.0%) | -72.41%(-16.4%) |
| Sep 2002 | - | -86.58%(-16.8%) |
| Jun 2002 | - | -104.01%(+3.9%) |
| Mar 2002 | - | -100.07%(+39.3%) |
| Dec 2001 | -138.59%(-3.5%) | -71.86%(+12.6%) |
| Sep 2001 | - | -63.81%(-79.0%) |
| Jun 2001 | - | -303.52%(-38.5%) |
| Mar 2001 | - | -493.14%(+153.4%) |
| Dec 2000 | -143.56%(-17.8%) | -194.64%(+557.8%) |
| Sep 2000 | - | -29.59%(-85.5%) |
| Jun 2000 | - | -204.75%(-54.7%) |
| Mar 2000 | - | -452.07%(+144.0%) |
| Dec 1999 | -174.58%(+59.1%) | -185.26%(+58.4%) |
| Sep 1999 | - | -116.98%(-49.0%) |
| Jun 1999 | - | -229.17%(+20.0%) |
| Mar 1999 | - | -190.91%(-12.0%) |
| Dec 1998 | -109.73%(+14.7%) | -216.88%(+4211.7%) |
| Sep 1998 | - | -5.03%(-97.9%) |
| Jun 1998 | - | -237.93%(+20.0%) |
| Mar 1998 | - | -198.28%(+74.6%) |
| Dec 1997 | -95.68%(-18.6%) | -113.54%(+550.3%) |
| Sep 1997 | - | -17.46%(-89.2%) |
| Jun 1997 | - | -162.07%(-13.3%) |
| Mar 1997 | - | -186.96%(+50.0%) |
| Dec 1996 | -117.50%(-35.8%) | -124.62%(+5.9%) |
| Sep 1996 | - | -117.65%(-24.3%) |
| Jun 1996 | - | -155.32%(+94.9%) |
| Mar 1996 | - | -79.69%(-46.9%) |
| Dec 1995 | -182.88%(+1.5%) | -150.00%(-19.6%) |
| Sep 1995 | - | -186.49%(+4.3%) |
| Jun 1995 | - | -178.79%(-21.2%) |
| Mar 1995 | - | -226.92%(+34.5%) |
| Dec 1994 | -180.22%(+0.7%) | - |
| Sep 1994 | - | -168.75%(+2.6%) |
| Jun 1994 | - | -164.52%(+151.6%) |
| Mar 1994 | - | -65.38%(-58.8%) |
| Dec 1993 | -178.92%(-20.0%) | -158.62%(+13.8%) |
| Sep 1993 | - | -139.39%(-7.1%) |
| Jun 1993 | - | -150.00%(-20.6%) |
| Mar 1993 | - | -188.89%(-78.6%) |
| Dec 1992 | -223.56%(+60.2%) | -883.33%(+494.9%) |
| Sep 1992 | - | -148.48%(-20.6%) |
| Jun 1992 | - | -186.96%(-6.5%) |
| Mar 1992 | - | -200.00%(-50.0%) |
| Dec 1991 | -139.55%(-38.0%) | -400.00%(+233.3%) |
| Sep 1991 | - | -120.00%(-10.0%) |
| Jun 1991 | - | -133.33%(+81.8%) |
| Mar 1991 | - | -73.33%(-66.7%) |
| Dec 1990 | -225.00% | -220.00%(0.0%) |
| Sep 1990 | - | -220.00%(0.0%) |
| Jun 1990 | - | -220.00%(0.0%) |
| Mar 1990 | - | -220.00% |
FAQ
- What is Ionis Pharmaceuticals, Inc. annual net profit margin?
- What is the all time high annual net margin for Ionis Pharmaceuticals, Inc.?
- What is Ionis Pharmaceuticals, Inc. annual net margin year-on-year change?
- What is Ionis Pharmaceuticals, Inc. quarterly net profit margin?
- What is the all time high quarterly net margin for Ionis Pharmaceuticals, Inc.?
- What is Ionis Pharmaceuticals, Inc. quarterly net margin year-on-year change?
What is Ionis Pharmaceuticals, Inc. annual net profit margin?
The current annual net margin of IONS is -64.37%
What is the all time high annual net margin for Ionis Pharmaceuticals, Inc.?
Ionis Pharmaceuticals, Inc. all-time high annual net profit margin is 36.37%
What is Ionis Pharmaceuticals, Inc. annual net margin year-on-year change?
Over the past year, IONS annual net profit margin has changed by -17.87% (-38.43%)
What is Ionis Pharmaceuticals, Inc. quarterly net profit margin?
The current quarterly net margin of IONS is 27.33%
What is the all time high quarterly net margin for Ionis Pharmaceuticals, Inc.?
Ionis Pharmaceuticals, Inc. all-time high quarterly net profit margin is 51.79%
What is Ionis Pharmaceuticals, Inc. quarterly net margin year-on-year change?
Over the past year, IONS quarterly net profit margin has changed by +56.75% (+192.90%)