Annual Net Margin
-40.36%24.01%+37.30%
Summary
- Current Value
- As of today, IONS annual net margin is -40.36%, up +37.30% on
- Historical Performance
- IONS annual net margin is up +12.11% over the past 3 years, up +38.64% over the past 5 years
- All-Time High Comparison
- IONS annual net margin is currently -210.97% below its historical high of 36.37% set on
- 3-Year Low Comparison
- IONS annual net margin is +37.30% above its 3-year low of -64.37% reached on
- Sector Comparison
- IONS annual net margin is higher than 51.78% of companies in Healthcare sector
Net Margin Chart
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Series
SUGGESTED SERIES
Performance
| Metric | Date | Value | 1Y | 3Y | 5Y | 15Y |
|---|---|---|---|---|---|---|
| Annual Net Margin | -40.36% | +37.3% | +12.1% | +38.6% | +28.5% | |
| Quarterly Net Margin | -112.81% | -146.2% | -229.8% | +8.1% | -113.1% | |
| Price | $81.15 | +158.8% | +124.1% | +54.9% | +793.7% | |
| PE Ratio | - | – | – | – | – | |
| Annual Revenue | $944.00M | +33.9% | +60.7% | +29.4% | +770.3% | |
| Annual Net Income | -$381.00M | +16.1% | -41.3% | +20.6% | -522.0% | |
| Annual Gross Margin | 98.31% | +3.2% | +4.8% | +2.4% | +100.0% | |
| Annual Operating Margin | -40.47% | +39.9% | +42.0% | -71.5% | +6.3% |
Net Margin Highs
| Period | High | Date | Current |
|---|---|---|---|
| 3Y | -40.36% | at high | |
| 5Y | -3.53% | -1043.3% | |
| All | 36.37% | -211.0% |
Net Margin Lows
| Period | Low | Date | Current |
|---|---|---|---|
| 3Y | -64.37% | +37.3% | |
| 5Y | -65.78% | N/A | +38.6% |
| All | -334.33% | +87.9% |
Net Margin History
FAQ
What is the current annual net margin of IONS?
As of today, IONS annual net margin is -40.36%
What is 1-year change in IONS annual net margin?
IONS annual net margin is up +37.30% year-over-year
What is 3-year change in IONS annual net margin?
IONS annual net margin is up +12.11% over the past 3 years
How far is IONS annual net margin from its all-time high?
IONS annual net margin is currently -210.97% below its historical high of 36.37% set on December 31, 2018
How does IONS annual net margin rank versus sector peers?
IONS annual net margin is higher than 51.78% of companies in Healthcare sector
When is IONS next annual earnings release?
As of today, the next annual earnings release for IONS has not been scheduled
Quarterly Net Margin
-112.81%30.75%-37.47%
Summary
- Current Value
- As of today, IONS quarterly net margin is -112.81%, down -37.47% on
- Historical Performance
- IONS quarterly net margin is down -146.20% year-over-year, down -229.76% over the past 3 years
- All-Time High Comparison
- IONS quarterly net margin is currently -220.37% below its historical high of 93.72% set on
- 3-Year Low Comparison
- IONS quarterly net margin is +5.60% above its 3-year low of -119.50% reached on
- Sector Comparison
- IONS quarterly net margin is higher than 35.56% of companies in Healthcare sector
Performance
| Metric | Date | Value | 3M | 1Y | 3Y | 5Y |
|---|---|---|---|---|---|---|
| Quarterly Net Margin | -112.81% | -37.5% | -146.2% | -229.8% | +8.1% | |
| Annual Net Margin | -40.36% | – | +37.3% | +12.1% | +38.6% | |
| Price | $81.15 | -1.9% | +158.8% | +124.1% | +54.9% | |
| PE Ratio | - | – | – | – | – | |
| Quarterly Revenue | $203.00M | +29.5% | -10.6% | +33.5% | -30.0% | |
| Quarterly Net Income | -$229.00M | -78.1% | -120.2% | -340.4% | +35.7% | |
| Quarterly Gross Margin | 96.06% | -0.6% | +0.1% | +3.6% | -1.4% | |
| Quarterly Operating Margin | -105.91% | -3.6% | -118.5% | +22.6% | -1235.6% |
Quarterly Net Margin Highs
| Period | High | Date | Current |
|---|---|---|---|
| 1Y | 27.33% | -512.8% | |
| 3Y | 27.33% | -512.8% | |
| 5Y | 51.07% | -320.9% | |
| All | 93.72% | -220.4% |
Quarterly Net Margin Lows
| Period | Low | Date | Current |
|---|---|---|---|
| 1Y | -112.81% | at low | |
| 3Y | -119.50% | +5.6% | |
| 5Y | -122.76% | N/A | +8.1% |
| All | -883.33% | +87.2% |
Quarterly Net Margin History
FAQ
What is the current quarterly net margin of IONS?
As of today, IONS quarterly net margin is -112.81%
What is IONS quarterly net margin most recent change?
IONS quarterly net margin was down -37.47% on December 31, 2025
What is 1-year change in IONS quarterly net margin?
IONS quarterly net margin is down -146.20% year-over-year
How far is IONS quarterly net margin from its all-time high?
IONS quarterly net margin is currently -220.37% below its historical high of 93.72% set on September 30, 2007
How does IONS quarterly net margin rank versus sector peers?
IONS quarterly net margin is higher than 35.56% of companies in Healthcare sector
When is IONS next earnings release?
As of today, the next earnings release for IONS has not been scheduled
Net Margin Formula
Net Margin = Net Income
Revenue × 100%
Revenue × 100%
Data Sources & References
- IONS Official Website www.ionis.com
- Most Recent Quarterly Report (10-Q) www.sec.gov/Archives/edgar/data/874015/000087401526000115/0000874015-26-000115-index.htm
- Most Recent Annual Report (10-K) www.sec.gov/Archives/edgar/data/874015/000087401526000115/0000874015-26-000115-index.htm
- IONS Profile on Yahoo Finance finance.yahoo.com/quote/IONS
- IONS Profile on NASDAQ.com www.nasdaq.com/market-activity/stocks/ions