Annual Net Margin:
-64.37%-17.87%(-38.43%)Summary
- As of today, IONS annual net profit margin is -64.37%, with the most recent change of -17.87% (-38.43%) on December 31, 2024.
- During the last 3 years, IONS annual net margin has fallen by -60.84% (-1723.51%).
- IONS annual net margin is now -276.99% below its all-time high of 36.37%, reached on December 31, 2018.
Performance
IONS Net Margin Chart
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Range
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Quarterly Net Margin:
27.33%+138.97%(+124.48%)Summary
- As of today, IONS quarterly net profit margin is 27.33%, with the most recent change of +138.97% (+124.48%) on June 30, 2025.
- Over the past year, IONS quarterly net margin has increased by +56.75% (+192.90%).
- IONS quarterly net margin is now -70.84% below its all-time high of 93.72%, reached on September 30, 2007.
Performance
IONS Quarterly Net Margin Chart
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Net Margin Formula
Net Margin = Net Income
Revenue ✕ 100%
Revenue ✕ 100%
IONS Net Margin Trends
| PeriodPeriod | AnnualAnnual | QuarterlyQuarterly |
|---|---|---|
| 1Y1 Year | -38.4% | +192.9% |
| 3Y3 Years | -1723.5% | +134.8% |
| 5Y5 Years | -336.4% | +205.9% |
IONS Net Margin Highs & Lows
| PeriodPeriod | Annual vs HighAnnual vs High | Annual vs LowAnnual vs Low | Quarter. vs HighQuarter. vs High | Quarter. vs LowQuarter. vs Low | |
|---|---|---|---|---|---|
| 3Y | 3-Year | -1723.5% | at low | at high | +122.9% |
| 5Y | 5-Year | -336.4% | +2.1% | -46.5% | +122.3% |
| All-Time | All-Time | -277.0% | +80.8% | -70.8% | +103.1% |
IONS Net Margin History
| Date | Annual | Quarterly |
|---|---|---|
| Jun 2025 | - | 27.33%(+124.5%) |
| Mar 2025 | - | -111.64%(-143.6%) |
| Dec 2024 | -64.37%(-38.4%) | -45.82%(+56.4%) |
| Sep 2024 | - | -104.98%(-256.8%) |
| Jun 2024 | - | -29.42%(+75.4%) |
| Mar 2024 | - | -119.50%(-4214.1%) |
| Dec 2023 | -46.50%(-1.3%) | -2.77%(+97.3%) |
| Sep 2023 | - | -102.22%(-125.8%) |
| Jun 2023 | - | -45.27%(+52.5%) |
| Mar 2023 | - | -95.25%(-178.4%) |
| Dec 2022 | -45.92%(-1200.8%) | -34.21%(-16.3%) |
| Sep 2022 | - | -29.41%(+62.6%) |
| Jun 2022 | - | -78.58%(-71.1%) |
| Mar 2022 | - | -45.92%(-189.9%) |
| Dec 2021 | -3.53%(+94.6%) | 51.07%(+182.4%) |
| Sep 2021 | - | -61.96%(+3.7%) |
| Jun 2021 | - | -64.31%(+20.1%) |
| Mar 2021 | - | -80.52%(+34.4%) |
| Dec 2020 | -65.78%(-341.6%) | -122.76%(-436.8%) |
| Sep 2020 | - | -22.87%(+11.4%) |
| Jun 2020 | - | -25.81%(+31.0%) |
| Mar 2020 | - | -37.40%(-190.8%) |
| Dec 2019 | 27.23%(-25.1%) | 41.19%(+275.1%) |
| Sep 2019 | - | 10.98%(+278.5%) |
| Jun 2019 | - | -6.15%(-119.4%) |
| Mar 2019 | - | 31.62%(+325.7%) |
| Dec 2018 | 36.37%(+2340.9%) | - |
| Sep 2018 | - | -14.01%(+70.8%) |
| Jun 2018 | - | -48.05%(-541.5%) |
| Mar 2018 | - | -7.49%(-232.9%) |
| Dec 2017 | 1.49%(+106.0%) | -2.25%(+64.5%) |
| Sep 2017 | - | -6.33%(-130.2%) |
| Jun 2017 | - | -2.75%(-135.5%) |
| Mar 2017 | - | 7.74%(-52.0%) |
| Dec 2016 | -24.97%(+19.8%) | 16.13%(+143.3%) |
| Sep 2016 | - | 6.63%(+104.5%) |
| Jun 2016 | - | -147.79%(+13.4%) |
| Mar 2016 | - | -170.63%(-23.2%) |
| Dec 2015 | -31.12%(-71.0%) | -138.51%(-90.2%) |
| Sep 2015 | - | -72.83%(-346.0%) |
| Jun 2015 | - | 29.60%(+210.8%) |
| Mar 2015 | - | -26.71%(-173.0%) |
| Dec 2014 | -18.20%(+55.8%) | 36.59%(+160.4%) |
| Sep 2014 | - | -60.54%(-186.0%) |
| Jun 2014 | - | -21.17%(+80.9%) |
| Mar 2014 | - | -111.08%(-93.3%) |
| Dec 2013 | -41.17%(+35.8%) | -57.46%(+44.8%) |
| Sep 2013 | - | -104.18%(-291.9%) |
| Jun 2013 | - | -26.58%(-588.6%) |
| Mar 2013 | - | -3.86%(+70.9%) |
| Dec 2012 | -64.16%(+25.0%) | -13.27%(+95.9%) |
| Sep 2012 | - | -324.45%(>-9900.0%) |
| Jun 2012 | - | -2.55%(+97.5%) |
| Mar 2012 | - | -103.27%(-67.0%) |
| Dec 2011 | -85.58%(-51.5%) | -61.83%(+52.4%) |
| Sep 2011 | - | -129.78%(-80.1%) |
| Jun 2011 | - | -72.07%(+23.8%) |
| Mar 2011 | - | -94.55%(-78.6%) |
| Dec 2010 | -56.47%(-96.4%) | -52.93%(-21.7%) |
| Sep 2010 | - | -43.51%(+59.3%) |
| Jun 2010 | - | -107.02%(-231.6%) |
| Mar 2010 | - | -32.27%(+38.1%) |
| Dec 2009 | -28.75%(-271.0%) | -52.17%(-141.3%) |
| Sep 2009 | - | -21.62%(-228.6%) |
| Jun 2009 | - | -6.58%(-115.7%) |
| Dec 2008 | -7.75%(+84.5%) | 42.02%(+689.8%) |
| Sep 2008 | - | 5.32%(+144.2%) |
| Jun 2008 | - | -12.03%(+51.3%) |
| Mar 2008 | - | -24.69%(+95.4%) |
| Dec 2007 | -49.96% | -537.08%(-673.1%) |
| Date | Annual | Quarterly |
|---|---|---|
| Sep 2007 | - | 93.72%(+119.2%) |
| Jun 2007 | - | -488.51%(+39.6%) |
| Mar 2007 | - | -809.22%(-743.0%) |
| Dec 2006 | -280.96%(-55.7%) | -95.99%(+41.9%) |
| Sep 2006 | - | -165.14%(+54.2%) |
| Jun 2006 | - | -360.69%(-2.3%) |
| Mar 2006 | - | -352.56%(-552.4%) |
| Dec 2005 | -180.40%(+46.0%) | -54.04%(+73.4%) |
| Sep 2005 | - | -203.43%(-9.6%) |
| Jun 2005 | - | -185.60%(+53.4%) |
| Mar 2005 | - | -398.52%(+21.1%) |
| Dec 2004 | -334.33%(-75.9%) | -505.40%(-40.5%) |
| Sep 2004 | - | -359.71%(-36.4%) |
| Jun 2004 | - | -263.63%(-23.3%) |
| Mar 2004 | - | -213.82%(+18.3%) |
| Dec 2003 | -190.03%(-110.9%) | -261.62%(-33.1%) |
| Sep 2003 | - | -196.59%(-27.8%) |
| Jun 2003 | - | -153.82%(+11.6%) |
| Mar 2003 | - | -173.98%(-140.3%) |
| Dec 2002 | -90.10%(+35.0%) | -72.41%(+16.4%) |
| Sep 2002 | - | -86.58%(+16.8%) |
| Jun 2002 | - | -104.01%(-3.9%) |
| Mar 2002 | - | -100.07%(-39.3%) |
| Dec 2001 | -138.59%(+3.5%) | -71.86%(-12.6%) |
| Sep 2001 | - | -63.81%(+79.0%) |
| Jun 2001 | - | -303.52%(+38.5%) |
| Mar 2001 | - | -493.14%(-153.4%) |
| Dec 2000 | -143.56%(+17.8%) | -194.64%(-557.8%) |
| Sep 2000 | - | -29.59%(+85.5%) |
| Jun 2000 | - | -204.75%(+54.7%) |
| Mar 2000 | - | -452.07%(-143.2%) |
| Dec 1999 | -174.58%(-59.1%) | -185.92%(-59.1%) |
| Sep 1999 | - | -116.85%(+49.0%) |
| Jun 1999 | - | -229.23%(-19.6%) |
| Mar 1999 | - | -191.67%(+49.9%) |
| Dec 1998 | -109.73%(-14.7%) | -382.74%(-8256.8%) |
| Sep 1998 | - | -4.58%(+97.7%) |
| Jun 1998 | - | -196.47%(-17.5%) |
| Mar 1998 | - | -167.16%(-47.2%) |
| Dec 1997 | -95.68%(+18.6%) | -113.54%(-550.3%) |
| Sep 1997 | - | -17.46%(+89.2%) |
| Jun 1997 | - | -162.07%(+13.3%) |
| Mar 1997 | - | -186.96%(-50.0%) |
| Dec 1996 | -117.50%(+35.8%) | -124.62%(-5.9%) |
| Sep 1996 | - | -117.65%(+24.3%) |
| Jun 1996 | - | -155.32%(-94.9%) |
| Mar 1996 | - | -79.69%(+46.9%) |
| Dec 1995 | -182.88%(-1.5%) | -150.00%(+19.6%) |
| Sep 1995 | - | -186.49%(-4.3%) |
| Jun 1995 | - | -178.79%(+21.2%) |
| Mar 1995 | - | -226.92%(-34.5%) |
| Dec 1994 | -180.22%(-0.7%) | - |
| Sep 1994 | - | -168.75%(-2.6%) |
| Jun 1994 | - | -164.52%(-151.6%) |
| Mar 1994 | - | -65.38%(+58.8%) |
| Dec 1993 | -178.92%(+20.0%) | -158.62%(-13.8%) |
| Sep 1993 | - | -139.39%(+7.1%) |
| Jun 1993 | - | -150.00%(+20.6%) |
| Mar 1993 | - | -188.89%(+78.6%) |
| Dec 1992 | -223.56%(-60.2%) | -883.33%(-494.9%) |
| Sep 1992 | - | -148.48%(+20.6%) |
| Jun 1992 | - | -186.96%(+6.5%) |
| Mar 1992 | - | -200.00%(+50.0%) |
| Dec 1991 | -139.55%(+38.0%) | -400.00%(-233.3%) |
| Sep 1991 | - | -120.00%(+10.0%) |
| Jun 1991 | - | -133.33%(-81.8%) |
| Mar 1991 | - | -73.33%(+66.7%) |
| Dec 1990 | -225.00% | -220.00%(0.0%) |
| Sep 1990 | - | -220.00%(0.0%) |
| Jun 1990 | - | -220.00%(0.0%) |
| Mar 1990 | - | -220.00% |
FAQ
- What is Ionis Pharmaceuticals, Inc. annual net profit margin?
- What is the all-time high annual net margin for Ionis Pharmaceuticals, Inc.?
- What is Ionis Pharmaceuticals, Inc. annual net margin year-on-year change?
- What is Ionis Pharmaceuticals, Inc. quarterly net profit margin?
- What is the all-time high quarterly net margin for Ionis Pharmaceuticals, Inc.?
- What is Ionis Pharmaceuticals, Inc. quarterly net margin year-on-year change?
What is Ionis Pharmaceuticals, Inc. annual net profit margin?
The current annual net margin of IONS is -64.37%
What is the all-time high annual net margin for Ionis Pharmaceuticals, Inc.?
Ionis Pharmaceuticals, Inc. all-time high annual net profit margin is 36.37%
What is Ionis Pharmaceuticals, Inc. annual net margin year-on-year change?
Over the past year, IONS annual net profit margin has changed by -17.87% (-38.43%)
What is Ionis Pharmaceuticals, Inc. quarterly net profit margin?
The current quarterly net margin of IONS is 27.33%
What is the all-time high quarterly net margin for Ionis Pharmaceuticals, Inc.?
Ionis Pharmaceuticals, Inc. all-time high quarterly net profit margin is 93.72%
What is Ionis Pharmaceuticals, Inc. quarterly net margin year-on-year change?
Over the past year, IONS quarterly net profit margin has changed by +56.75% (+192.90%)