Annual Net Margin
-64.37%17.87%-38.43%
Summary
- Current Value
- As of today, IONS annual net margin is -64.37%, down -38.43% on
- Historical Performance
- IONS annual net margin is down -1723.51% over the past 3 years, and down -336.39% over the past 5 years
- All-Time High Comparison
- IONS annual net margin is currently -276.99% below its historical high of 36.37% set on
- 3-Year Low Comparison
- IONS annual net margin is at its 3-year low
- Sector Comparison
- IONS annual net margin is higher than 47.57% of companies in Healthcare sector
Net Margin Chart
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Series
SUGGESTED SERIES
Performance
| Metric | Date | Value | 1Y | 3Y | 5Y | 15Y |
|---|---|---|---|---|---|---|
| Annual Net Margin | -64.37% | -38.4% | -1723.5% | -336.4% | -123.9% | |
| Quarterly Net Margin | -82.06% | +21.8% | -179.0% | -258.8% | -88.6% | |
| Price | $79.48 | +127.5% | +99.5% | +33.2% | +700.4% | |
| PE Ratio | - | – | – | – | – | |
| Annual Revenue | $705.14M | -10.5% | -13.0% | -37.2% | +479.9% | |
| Annual Net Income | -$453.90M | -23.9% | -1487.2% | -248.5% | -1198.5% | |
| Annual Gross Margin | 95.29% | -0.7% | -1.0% | -2.9% | +100.0% | |
| Annual Operating Margin | -67.38% | -50.0% | -3602.2% | -306.8% | -197.5% |
Net Margin Highs
| Period | High | Date | Current |
|---|---|---|---|
| 3Y | -45.92% | N/A | -40.2% |
| 5Y | -3.53% | -1723.5% | |
| All | 36.37% | -277.0% |
Net Margin Lows
| Period | Low | Date | Current |
|---|---|---|---|
| 3Y | -64.37% | at low | |
| 5Y | -65.78% | N/A | +2.1% |
| All | -334.33% | +80.8% |
Net Margin History
FAQ
What is the current annual net margin of IONS?
As of today, IONS annual net margin is -64.37%
What is 1-year change in IONS annual net margin?
IONS annual net margin is down -38.43% year-over-year
What is 3-year change in IONS annual net margin?
IONS annual net margin is down -1723.51% over the past 3 years
How far is IONS annual net margin from its all-time high?
IONS annual net margin is currently -276.99% below its historical high of 36.37% set on December 31, 2018
How does IONS annual net margin rank versus sector peers?
IONS annual net margin is higher than 47.57% of companies in Healthcare sector
When is IONS next annual earnings release?
The next annual earnings release for IONS is on
Quarterly Net Margin
-82.06%109.39%-400.26%
Summary
- Current Value
- As of today, IONS quarterly net margin is -82.06%, down -400.26% on
- Historical Performance
- IONS quarterly net margin is up +21.83% year-over-year, and down -179.02% over the past 3 years
- All-Time High Comparison
- IONS quarterly net margin is currently -187.56% below its historical high of 93.72% set on
- 3-Year Low Comparison
- IONS quarterly net margin is +31.33% above its 3-year low of -119.50% reached on
- Sector Comparison
- IONS quarterly net margin is higher than 39.12% of companies in Healthcare sector
Performance
| Metric | Date | Value | 3M | 1Y | 3Y | 5Y |
|---|---|---|---|---|---|---|
| Quarterly Net Margin | -82.06% | -400.3% | +21.8% | -179.0% | -258.8% | |
| Annual Net Margin | -64.37% | – | -38.4% | -1723.5% | -336.4% | |
| Price | $79.48 | +12.6% | +127.5% | +99.5% | +33.2% | |
| PE Ratio | - | – | – | – | – | |
| Quarterly Revenue | $156.72M | -65.3% | +17.1% | -1.9% | -2.1% | |
| Quarterly Net Income | -$128.61M | -204.1% | +8.4% | -173.7% | -251.3% | |
| Quarterly Gross Margin | 96.67% | -1.8% | +1.7% | +0.8% | +1.4% | |
| Quarterly Operating Margin | -102.21% | -430.5% | +8.0% | -176.0% | -347.9% |
Quarterly Net Margin Highs
| Period | High | Date | Current |
|---|---|---|---|
| 1Y | 27.33% | -400.3% | |
| 3Y | 27.33% | -400.3% | |
| 5Y | 51.07% | -260.7% | |
| All | 93.72% | -187.6% |
Quarterly Net Margin Lows
| Period | Low | Date | Current |
|---|---|---|---|
| 1Y | -111.64% | +26.5% | |
| 3Y | -119.50% | +31.3% | |
| 5Y | -122.76% | N/A | +33.1% |
| All | -883.33% | +90.7% |
Quarterly Net Margin History
FAQ
What is the current quarterly net margin of IONS?
As of today, IONS quarterly net margin is -82.06%
What is IONS quarterly net margin most recent change?
IONS quarterly net margin was down -400.26% on September 1, 2025
What is 1-year change in IONS quarterly net margin?
IONS quarterly net margin is up +21.83% year-over-year
How far is IONS quarterly net margin from its all-time high?
IONS quarterly net margin is currently -187.56% below its historical high of 93.72% set on September 30, 2007
How does IONS quarterly net margin rank versus sector peers?
IONS quarterly net margin is higher than 39.12% of companies in Healthcare sector
When is IONS next earnings release?
The next earnings release for IONS is on
Net Margin Formula
Net Margin = Net Income
Revenue × 100%
Revenue × 100%
Data Sources & References
- IONS Official Website www.ionis.com
- Most Recent Annual Report (10-K) www.sec.gov/Archives/edgar/data/874015/000087401525000089/0000874015-25-000089-index.htm
- IONS Profile on Yahoo Finance finance.yahoo.com/quote/IONS
- IONS Profile on NASDAQ.com www.nasdaq.com/market-activity/stocks/ions