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Ionis Pharmaceuticals (IONS) Operating profit

annual operating profit:

-$475.11M-$121.40M(-34.32%)
December 31, 2024

Summary

  • As of today (May 29, 2025), IONS annual operating income is -$475.11 million, with the most recent change of -$121.40 million (-34.32%) on December 31, 2024.
  • During the last 3 years, IONS annual operating profit has fallen by -$460.37 million (-3123.47%).
  • IONS annual operating profit is now -229.85% below its all-time high of $365.88 million, reached on December 31, 2019.

Performance

IONS Operating profit Chart

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quarterly operating profit:

-$146.95M-$36.10M(-32.57%)
March 31, 2025

Summary

  • As of today (May 29, 2025), IONS quarterly operating income is -$146.95 million, with the most recent change of -$36.10 million (-32.57%) on March 31, 2025.
  • Over the past year, IONS quarterly operating profit has increased by +$2.57 million (+1.72%).
  • IONS quarterly operating profit is now -156.38% below its all-time high of $260.65 million, reached on December 31, 2019.

Performance

IONS quarterly operating profit Chart

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TTM operating profit:

-$472.50M+$2.57M(+0.54%)
March 31, 2025

Summary

  • As of today (May 29, 2025), IONS TTM operating income is -$472.50 million, with the most recent change of +$2.57 million (+0.54%) on March 31, 2025.
  • Over the past year, IONS TTM operating profit has dropped by -$83.36 million (-21.42%).
  • IONS TTM operating profit is now -229.14% below its all-time high of $365.88 million, reached on December 31, 2019.

Performance

IONS TTM operating profit Chart

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Operating profit Formula

Operating Profit = Gross Profit − Operating Expenses

IONS Operating profit Trends

PeriodPeriodAnnualAnnualQuarterlyQuarterlyTTMTTM
1 y1 year-34.3%+1.7%-21.4%
3 y3 years-3123.5%-155.5%-3122.8%
5 y5 years-229.8%-140.4%-357.9%

IONS Operating profit Highs & Lows

PeriodPeriodAnnual vs highAnnual vs highAnnual vs lowAnnual vs lowQuarter. vs highQuarter. vs highQuarter. vs lowQuarter. vs lowTTM vs highTTM vs highTTM vs lowTTM vs low
3 y3-year-3123.5%at low-2304.2%+29.3%-2807.6%+15.0%
5 y5-year-229.8%at low-166.9%+29.3%-357.9%+15.0%
alltimeall time-229.8%at low-156.4%+29.3%-229.1%+15.0%

IONS Operating profit History

DateAnnualQuarterlyTTM
Mar 2025
-
-$146.95M(+32.6%)
-$472.50M(-0.5%)
Dec 2024
-$475.11M(+34.3%)
-$110.84M(-25.4%)
-$475.07M(+28.3%)
Sep 2024
-
-$148.62M(+124.9%)
-$370.34M(+1.5%)
Jun 2024
-
-$66.09M(-55.8%)
-$365.04M(-6.2%)
Mar 2024
-
-$149.52M(+2346.3%)
-$389.14M(+10.0%)
Dec 2023
-$353.71M(-13.8%)
-$6.11M(-95.7%)
-$353.77M(-36.3%)
Sep 2023
-
-$143.31M(+58.9%)
-$555.62M(+17.9%)
Jun 2023
-
-$90.19M(-21.0%)
-$471.44M(+1.0%)
Mar 2023
-
-$114.15M(-45.1%)
-$466.76M(+13.8%)
Dec 2022
-$410.19M(+2683.0%)
-$207.96M(+251.7%)
-$410.12M(-2450.1%)
Sep 2022
-
-$59.14M(-30.8%)
$17.45M(-311.1%)
Jun 2022
-
-$85.51M(+48.7%)
-$8.27M(-152.9%)
Mar 2022
-
-$57.50M(-126.2%)
$15.63M(-206.1%)
Dec 2021
-$14.74M(-90.2%)
$219.60M(-358.8%)
-$14.74M(-93.7%)
Sep 2021
-
-$84.86M(+37.7%)
-$234.84M(+25.9%)
Jun 2021
-
-$61.61M(-29.9%)
-$186.47M(+5.6%)
Mar 2021
-
-$87.87M(>+9900.0%)
-$176.62M(+17.8%)
Dec 2020
-$149.96M(-141.0%)
-$499.00K(-98.6%)
-$149.88M(-234.7%)
Sep 2020
-
-$36.49M(-29.5%)
$111.28M(-26.0%)
Jun 2020
-
-$51.75M(-15.3%)
$150.29M(-18.0%)
Mar 2020
-
-$61.13M(-123.5%)
$183.22M(-49.9%)
Dec 2019
$365.88M(-696.2%)
$260.65M(>+9900.0%)
$365.88M(+215.4%)
Sep 2019
-
$2.52M(-113.4%)
$116.02M(+22.2%)
Jun 2019
-
-$18.83M(-115.5%)
$94.92M(+49.6%)
Mar 2019
-
$121.53M(+1026.9%)
$63.47M(-203.4%)
Dec 2018
-$61.37M(-297.7%)
$10.79M(-158.1%)
-$61.37M(-21.7%)
Sep 2018
-
-$18.57M(-63.1%)
-$78.35M(+61.7%)
Jun 2018
-
-$50.28M(+1423.2%)
-$48.47M(-686.7%)
Mar 2018
-
-$3.30M(-46.8%)
$8.26M(-73.4%)
Dec 2017
$31.05M(-254.0%)
-$6.20M(-154.8%)
$31.05M(-70.3%)
Sep 2017
-
$11.31M(+75.4%)
$104.56M(-4.4%)
Jun 2017
-
$6.45M(-66.9%)
$109.35M(+102.6%)
Mar 2017
-
$19.48M(-71.1%)
$53.98M(-367.7%)
Dec 2016
-$20.16M(-73.4%)
$67.31M(+317.9%)
-$20.16M(-86.6%)
Sep 2016
-
$16.11M(-132.9%)
-$150.41M(-29.9%)
Jun 2016
-
-$48.93M(-10.5%)
-$214.66M(+77.3%)
Mar 2016
-
-$54.65M(-13.2%)
-$121.08M(+59.8%)
Dec 2015
-$75.76M(+58.7%)
-$62.94M(+30.8%)
-$75.76M(+2664.1%)
Sep 2015
-
-$48.14M(-207.8%)
-$2.74M(-111.5%)
Jun 2015
-
$44.65M(-578.5%)
$23.90M(-187.3%)
Mar 2015
-
-$9.33M(-192.6%)
-$27.39M(-42.6%)
Dec 2014
-$47.73M(-7.6%)
$10.08M(-146.9%)
-$47.73M(-38.5%)
Sep 2014
-
-$21.49M(+223.2%)
-$77.67M(-4.9%)
Jun 2014
-
-$6.65M(-77.6%)
-$81.68M(-1.5%)
Mar 2014
-
-$29.67M(+49.4%)
-$82.96M(+60.6%)
Dec 2013
-$51.67M(-25.0%)
-$19.86M(-22.1%)
-$51.67M(-10.8%)
Sep 2013
-
-$25.50M(+221.7%)
-$57.93M(-4.2%)
Jun 2013
-
-$7.93M(-587.9%)
-$60.47M(+23.8%)
Mar 2013
-
$1.63M(-106.2%)
-$48.84M(-29.1%)
Dec 2012
-$68.92M(-3.1%)
-$26.12M(-6.9%)
-$68.92M(+12.2%)
Sep 2012
-
-$28.05M(-858.8%)
-$61.42M(+10.3%)
Jun 2012
-
$3.70M(-120.0%)
-$55.69M(-24.2%)
Mar 2012
-
-$18.45M(-0.9%)
-$73.45M(+3.3%)
Dec 2011
-$71.10M(+47.0%)
-$18.62M(-16.6%)
-$71.10M(+4.0%)
Sep 2011
-
-$22.32M(+58.7%)
-$68.34M(+24.3%)
Jun 2011
-
-$14.06M(-12.7%)
-$54.97M(-7.7%)
Mar 2011
-
-$16.11M(+1.6%)
-$59.59M(+23.2%)
Dec 2010
-$48.36M(+75.6%)
-$15.86M(+77.2%)
-$48.36M(+9.5%)
Sep 2010
-
-$8.95M(-52.1%)
-$44.17M(-3.2%)
Jun 2010
-
-$18.67M(+282.6%)
-$45.62M(+43.6%)
Mar 2010
-
-$4.88M(-58.2%)
-$31.78M(+15.4%)
Dec 2009
-$27.54M(+110.9%)
-$11.67M(+12.3%)
-$27.54M(+15.0%)
Sep 2009
-
-$10.40M(+115.4%)
-$23.94M(+79.1%)
Jun 2009
-
-$4.83M(+651.9%)
-$13.37M(+79.2%)
Mar 2009
-
-$642.00K(-92.1%)
-$7.46M(-42.9%)
Dec 2008
-$13.06M(-60.3%)
-$8.08M(-4688.6%)
-$13.06M(+76.5%)
Sep 2008
-
$176.00K(-83.7%)
-$7.40M(-397.9%)
Jun 2008
-
$1.08M(-117.3%)
$2.48M(-113.6%)
Mar 2008
-
-$6.24M(+158.5%)
-$18.26M(-44.5%)
Dec 2007
-$32.92M
-$2.41M(-124.0%)
-$32.92M(-25.9%)
DateAnnualQuarterlyTTM
Sep 2007
-
$10.06M(-151.2%)
-$44.42M(-39.2%)
Jun 2007
-
-$19.66M(-5.9%)
-$73.02M(+3.3%)
Mar 2007
-
-$20.90M(+50.2%)
-$70.68M(+7.5%)
Dec 2006
-$65.75M(+30.9%)
-$13.91M(-25.0%)
-$65.75M(+8.0%)
Sep 2006
-
-$18.54M(+7.1%)
-$60.87M(+11.0%)
Jun 2006
-
-$17.32M(+8.4%)
-$54.82M(+10.1%)
Mar 2006
-
-$15.98M(+76.9%)
-$49.78M(-0.9%)
Dec 2005
-$50.22M(-41.2%)
-$9.03M(-27.7%)
-$50.22M(-17.1%)
Sep 2005
-
-$12.49M(+1.8%)
-$60.56M(-14.0%)
Jun 2005
-
-$12.27M(-25.3%)
-$70.45M(-11.4%)
Mar 2005
-
-$16.42M(-15.2%)
-$79.51M(-6.9%)
Dec 2004
-$85.43M(+10.7%)
-$19.37M(-13.4%)
-$85.43M(-2.4%)
Sep 2004
-
-$22.38M(+4.9%)
-$87.53M(+3.9%)
Jun 2004
-
-$21.34M(-4.5%)
-$84.22M(+4.5%)
Mar 2004
-
-$22.34M(+4.0%)
-$80.60M(+4.4%)
Dec 2003
-$77.17M(+56.1%)
-$21.48M(+12.7%)
-$77.18M(+17.7%)
Sep 2003
-
-$19.07M(+7.6%)
-$65.57M(+2.4%)
Jun 2003
-
-$17.72M(-6.3%)
-$64.01M(+9.2%)
Mar 2003
-
-$18.91M(+91.6%)
-$58.63M(+18.6%)
Dec 2002
-$49.44M(+7.2%)
-$9.87M(-43.6%)
-$49.44M(+4.6%)
Sep 2002
-
-$17.51M(+41.9%)
-$47.26M(+37.1%)
Jun 2002
-
-$12.34M(+27.0%)
-$34.46M(-10.7%)
Mar 2002
-
-$9.72M(+26.3%)
-$38.59M(-16.3%)
Dec 2001
-$46.10M(+59.0%)
-$7.70M(+63.5%)
-$46.10M(-4.8%)
Sep 2001
-
-$4.71M(-71.4%)
-$48.42M(+11.3%)
Jun 2001
-
-$16.46M(-4.5%)
-$43.50M(+23.5%)
Mar 2001
-
-$17.23M(+72.1%)
-$35.22M(+21.5%)
Dec 2000
-$28.99M(-32.7%)
-$10.01M(-4960.2%)
-$28.99M(-7.9%)
Sep 2000
-
$206.00K(-102.5%)
-$31.48M(-20.9%)
Jun 2000
-
-$8.18M(-25.7%)
-$39.78M(-8.8%)
Mar 2000
-
-$11.01M(-11.9%)
-$43.61M(+1.2%)
Dec 1999
-$43.10M(+32.6%)
-$12.50M(+54.3%)
-$43.10M(+6.9%)
Sep 1999
-
-$8.10M(-32.5%)
-$40.30M(+29.6%)
Jun 1999
-
-$12.00M(+14.3%)
-$31.10M(-3.1%)
Mar 1999
-
-$10.50M(+8.2%)
-$32.10M(-1.5%)
Dec 1998
-$32.50M(+3.8%)
-$9.70M(-981.8%)
-$32.60M(-1.8%)
Sep 1998
-
$1.10M(-108.5%)
-$33.20M(-10.0%)
Jun 1998
-
-$13.00M(+18.2%)
-$36.90M(+9.8%)
Mar 1998
-
-$11.00M(+6.8%)
-$33.60M(+6.7%)
Dec 1997
-$31.30M(+7.6%)
-$10.30M(+296.2%)
-$31.50M(+2.6%)
Sep 1997
-
-$2.60M(-73.2%)
-$30.70M(-11.8%)
Jun 1997
-
-$9.70M(+9.0%)
-$34.80M(+4.8%)
Mar 1997
-
-$8.90M(-6.3%)
-$33.20M(+14.1%)
Dec 1996
-$29.10M(+13.7%)
-$9.50M(+41.8%)
-$29.10M(+12.8%)
Sep 1996
-
-$6.70M(-17.3%)
-$25.80M(-2.6%)
Jun 1996
-
-$8.10M(+68.8%)
-$26.50M(+8.6%)
Mar 1996
-
-$4.80M(-22.6%)
-$24.40M(-5.1%)
Dec 1995
-$25.60M(+13.8%)
-$6.20M(-16.2%)
-$25.70M(-16.3%)
Sep 1995
-
-$7.40M(+23.3%)
-$30.70M(+8.5%)
Jun 1995
-
-$6.00M(-1.6%)
-$28.30M(+4.4%)
Mar 1995
-
-$6.10M(-45.5%)
-$27.10M(+6.3%)
Dec 1994
-$22.50M(+23.0%)
-$11.20M(+124.0%)
-$25.50M(+36.4%)
Sep 1994
-
-$5.00M(+4.2%)
-$18.70M(+3.3%)
Jun 1994
-
-$4.80M(+6.7%)
-$18.10M(+1.1%)
Mar 1994
-
-$4.50M(+2.3%)
-$17.90M(-3.2%)
Dec 1993
-$18.30M(-15.3%)
-$4.40M(0.0%)
-$18.50M(-14.0%)
Sep 1993
-
-$4.40M(-4.3%)
-$21.50M(-2.3%)
Jun 1993
-
-$4.60M(-9.8%)
-$22.00M(+1.9%)
Mar 1993
-
-$5.10M(-31.1%)
-$21.60M(+0.5%)
Dec 1992
-$21.60M(+105.7%)
-$7.40M(+51.0%)
-$21.50M(+12.6%)
Sep 1992
-
-$4.90M(+16.7%)
-$19.10M(+15.1%)
Jun 1992
-
-$4.20M(-16.0%)
-$16.60M(+12.9%)
Mar 1992
-
-$5.00M(0.0%)
-$14.70M(+33.6%)
Dec 1991
-$10.50M(+133.3%)
-$5.00M(+108.3%)
-$11.00M(-8.3%)
Sep 1991
-
-$2.40M(+4.3%)
-$12.00M(+31.9%)
Jun 1991
-
-$2.30M(+76.9%)
-$9.10M(+44.4%)
Mar 1991
-
-$1.30M(-78.3%)
-$6.30M(+40.0%)
Dec 1990
-$4.50M
-$6.00M(-1300.0%)
-$4.50M(-400.0%)
Sep 1990
-
$500.00K(0.0%)
$1.50M(+50.0%)
Jun 1990
-
$500.00K(0.0%)
$1.00M(+100.0%)
Mar 1990
-
$500.00K
$500.00K

FAQ

  • What is Ionis Pharmaceuticals annual operating income?
  • What is the all time high annual operating profit for Ionis Pharmaceuticals?
  • What is Ionis Pharmaceuticals annual operating profit year-on-year change?
  • What is Ionis Pharmaceuticals quarterly operating income?
  • What is the all time high quarterly operating profit for Ionis Pharmaceuticals?
  • What is Ionis Pharmaceuticals quarterly operating profit year-on-year change?
  • What is Ionis Pharmaceuticals TTM operating income?
  • What is the all time high TTM operating profit for Ionis Pharmaceuticals?
  • What is Ionis Pharmaceuticals TTM operating profit year-on-year change?

What is Ionis Pharmaceuticals annual operating income?

The current annual operating profit of IONS is -$475.11M

What is the all time high annual operating profit for Ionis Pharmaceuticals?

Ionis Pharmaceuticals all-time high annual operating income is $365.88M

What is Ionis Pharmaceuticals annual operating profit year-on-year change?

Over the past year, IONS annual operating income has changed by -$121.40M (-34.32%)

What is Ionis Pharmaceuticals quarterly operating income?

The current quarterly operating profit of IONS is -$146.95M

What is the all time high quarterly operating profit for Ionis Pharmaceuticals?

Ionis Pharmaceuticals all-time high quarterly operating income is $260.65M

What is Ionis Pharmaceuticals quarterly operating profit year-on-year change?

Over the past year, IONS quarterly operating income has changed by +$2.57M (+1.72%)

What is Ionis Pharmaceuticals TTM operating income?

The current TTM operating profit of IONS is -$472.50M

What is the all time high TTM operating profit for Ionis Pharmaceuticals?

Ionis Pharmaceuticals all-time high TTM operating income is $365.88M

What is Ionis Pharmaceuticals TTM operating profit year-on-year change?

Over the past year, IONS TTM operating income has changed by -$83.36M (-21.42%)
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