Annual Operating Margin
-40.47%26.90%+39.93%
Summary
- Current Value
- As of today, IONS annual operating margin is -40.47%, up +39.93% on
- Historical Performance
- IONS annual operating margin is up +42.05% over the past 3 years, down -71.48% over the past 5 years
- All-Time High Comparison
- IONS annual operating margin is currently -224.18% below its historical high of 32.59% set on
- 3-Year Low Comparison
- IONS annual operating margin is +42.05% above its 3-year low of -69.84% reached on an earlier date
- Sector Comparison
- IONS annual operating margin is higher than 51.08% of companies in Healthcare sector
Operating Margin Chart
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Series
SUGGESTED SERIES
Performance
| Metric | Date | Value | 1Y | 3Y | 5Y | 15Y |
|---|---|---|---|---|---|---|
| Annual Operating Margin | -40.47% | +39.9% | +42.0% | -71.5% | +6.3% | |
| Quarterly Operating Margin | -105.91% | -118.5% | +22.6% | -1235.6% | -76.5% | |
| Price | $81.15 | +158.8% | +124.1% | +54.9% | +793.7% | |
| PE Ratio | - | – | – | – | – | |
| Annual Revenue | $944.00M | +33.9% | +60.7% | +29.4% | +770.3% | |
| Annual Operating Profit | -$382.00M | +19.6% | +6.9% | -122.0% | -715.3% | |
| Annual Gross Margin | 98.31% | +3.2% | +4.8% | +2.4% | +100.0% | |
| Annual Net Margin | -40.36% | +37.3% | +12.1% | +38.6% | +28.5% |
Operating Margin Highs
| Period | High | Date | Current |
|---|---|---|---|
| 3Y | -40.47% | at high | |
| 5Y | -3.72% | -987.9% | |
| All | 32.59% | -224.2% |
Operating Margin Lows
| Period | Low | Date | Current |
|---|---|---|---|
| 3Y | -69.84% | N/A | +42.0% |
| 5Y | -69.84% | +42.0% | |
| All | -279.85% | +85.5% |
Operating Margin History
FAQ
What is the current annual operating margin of IONS?
As of today, IONS annual operating margin is -40.47%
What is 1-year change in IONS annual operating margin?
IONS annual operating margin is up +39.93% year-over-year
What is 3-year change in IONS annual operating margin?
IONS annual operating margin is up +42.05% over the past 3 years
How far is IONS annual operating margin from its all-time high?
IONS annual operating margin is currently -224.18% below its historical high of 32.59% set on December 31, 2019
How does IONS annual operating margin rank versus sector peers?
IONS annual operating margin is higher than 51.08% of companies in Healthcare sector
When is IONS next annual earnings release?
As of today, the next annual earnings release for IONS has not been scheduled
Quarterly Operating Margin
-105.91%3.70%-3.62%
Summary
- Current Value
- As of today, IONS quarterly operating margin is -105.91%, down -3.62% on
- Historical Performance
- IONS quarterly operating margin is down -118.55% year-over-year, up +22.60% over the past 3 years
- All-Time High Comparison
- IONS quarterly operating margin is currently -300.59% below its historical high of 52.80% set on
- 3-Year Low Comparison
- IONS quarterly operating margin is +22.60% above its 3-year low of -136.84% reached on an earlier date
- Sector Comparison
- IONS quarterly operating margin is higher than 35.99% of companies in Healthcare sector
Performance
| Metric | Date | Value | 3M | 1Y | 3Y | 5Y |
|---|---|---|---|---|---|---|
| Quarterly Operating Margin | -105.91% | -3.6% | -118.5% | +22.6% | -1235.6% | |
| Annual Operating Margin | -40.47% | – | +39.9% | +42.0% | -71.5% | |
| Price | $81.15 | -1.9% | +158.8% | +124.1% | +54.9% | |
| PE Ratio | - | – | – | – | – | |
| Quarterly Revenue | $203.00M | +29.5% | -10.6% | +33.5% | -30.0% | |
| Quarterly Operating Profit | -$215.00M | -34.2% | -95.5% | -3.4% | -834.8% | |
| Quarterly Gross Margin | 96.06% | -0.6% | +0.1% | +3.6% | -1.4% | |
| Quarterly Net Margin | -112.81% | -37.5% | -146.2% | -229.8% | +8.1% |
Quarterly Operating Margin Highs
| Period | High | Date | Current |
|---|---|---|---|
| 1Y | 30.93% | -442.4% | |
| 3Y | 30.93% | -442.4% | |
| 5Y | 50.23% | -310.9% | |
| All | 52.80% | -300.6% |
Quarterly Operating Margin Lows
| Period | Low | Date | Current |
|---|---|---|---|
| 1Y | -111.59% | +5.1% | |
| 3Y | -136.84% | N/A | +22.6% |
| 5Y | -136.84% | +22.6% | |
| All | -1,233.33% | +91.4% |
Quarterly Operating Margin History
FAQ
What is the current quarterly operating margin of IONS?
As of today, IONS quarterly operating margin is -105.91%
What is IONS quarterly operating margin most recent change?
IONS quarterly operating margin was down -3.62% on December 31, 2025
What is 1-year change in IONS quarterly operating margin?
IONS quarterly operating margin is down -118.55% year-over-year
How far is IONS quarterly operating margin from its all-time high?
IONS quarterly operating margin is currently -300.59% below its historical high of 52.80% set on December 31, 2019
How does IONS quarterly operating margin rank versus sector peers?
IONS quarterly operating margin is higher than 35.99% of companies in Healthcare sector
When is IONS next earnings release?
The next earnings release for IONS is on
Operating Margin Formula
Operating Profit Margin = Operating Profit
Revenue × 100%
Revenue × 100%
Data Sources & References
- IONS Official Website www.ionis.com
- Most Recent Quarterly Report (10-Q) www.sec.gov/Archives/edgar/data/874015/000087401526000115/0000874015-26-000115-index.htm
- Most Recent Annual Report (10-K) www.sec.gov/Archives/edgar/data/874015/000087401526000115/0000874015-26-000115-index.htm
- IONS Profile on Yahoo Finance finance.yahoo.com/quote/IONS
- IONS Profile on NASDAQ.com www.nasdaq.com/market-activity/stocks/ions