Annual Operating Margin
-40.47%26.90%+39.93%
Summary
- Current Value
- As of today, IONS annual operating margin is -40.47%, up +39.93% on
- Historical Performance
- IONS annual operating margin is up +42.05% over the past 3 years, down -71.48% over the past 5 years
- All-Time High Comparison
- IONS annual operating margin is currently -224.18% below its historical high of 32.59% set on
- 3-Year Low Comparison
- IONS annual operating margin is +42.05% above its 3-year low of -69.84% reached on an earlier date
- Sector Comparison
- IONS annual operating margin is higher than 48.31% of companies in Healthcare sector
Operating Margin Chart
SUGGESTED SERIES
Performance
| Metric | Date | Value | 1Y | 3Y | 5Y | 15Y |
|---|---|---|---|---|---|---|
| Annual Operating Margin | -40.47% | +39.9% | +42.0% | -71.5% | +6.3% | |
| Quarterly Operating Margin | -47.72% | +57.2% | +45.4% | +42.1% | +32.5% | |
| Price | $75.06 | +117.8% | +91.5% | +105.3% | +762.8% | |
| PE Ratio | - | – | – | – | – | |
| Annual Revenue | $943.71M | +33.8% | +60.7% | +29.4% | +770.0% | |
| Annual Operating Profit | -$382.00M | +19.6% | +6.9% | -122.0% | -715.3% | |
| Annual Gross Margin | 98.31% | +3.2% | +4.8% | +2.4% | +100.0% | |
| Annual Net Margin | -40.36% | +37.3% | +12.1% | +38.6% | +28.5% |
Operating Margin Highs
| Period | High | Date | Current |
|---|---|---|---|
| 3Y | -40.47% | at high | |
| 5Y | -3.72% | -987.9% | |
| All | 32.59% | -224.2% |
Operating Margin Lows
| Period | Low | Date | Current |
|---|---|---|---|
| 3Y | -69.84% | N/A | +42.0% |
| 5Y | -69.84% | +42.0% | |
| All | -279.85% | +85.5% |
Operating Margin History
FAQ
What is the current annual operating margin of IONS?
As of today, IONS annual operating margin is -40.47%
What is 1-year change in IONS annual operating margin?
IONS annual operating margin is up +39.93% year-over-year
What is 3-year change in IONS annual operating margin?
IONS annual operating margin is up +42.05% over the past 3 years
How far is IONS annual operating margin from its all-time high?
IONS annual operating margin is currently -224.18% below its historical high of 32.59% set on December 31, 2019
How does IONS annual operating margin rank versus sector peers?
IONS annual operating margin is higher than 48.31% of companies in Healthcare sector
When is IONS next annual earnings release?
As of today, the next annual earnings release for IONS has not been scheduled
Quarterly Operating Margin
-47.72%58.19%+54.94%
Summary
- Current Value
- As of today, IONS quarterly operating margin is -47.72%, up +54.94% on
- Historical Performance
- IONS quarterly operating margin is up +57.24% year-over-year, up +45.43% over the past 3 years
- All-Time High Comparison
- IONS quarterly operating margin is currently -190.38% below its historical high of 52.80% set on
- 3-Year Low Comparison
- IONS quarterly operating margin is +61.86% above its 3-year low of -125.12% reached on
- Sector Comparison
- IONS quarterly operating margin is higher than 43.54% of companies in Healthcare sector
Performance
| Metric | Date | Value | 3M | 1Y | 3Y | 5Y |
|---|---|---|---|---|---|---|
| Quarterly Operating Margin | -47.72% | +54.9% | +57.2% | +45.4% | +42.1% | |
| Annual Operating Margin | -40.47% | – | +39.9% | +42.0% | -71.5% | |
| Price | $75.06 | -9.7% | +117.8% | +91.5% | +105.3% | |
| PE Ratio | - | – | – | – | – | |
| Quarterly Revenue | $246.09M | +21.2% | +87.0% | +88.5% | +120.5% | |
| Quarterly Operating Profit | -$117.42M | +45.4% | +20.0% | -2.9% | -27.7% | |
| Quarterly Gross Margin | 95.76% | +1.7% | +1.0% | +1.1% | +2.6% | |
| Quarterly Net Margin | -37.60% | +66.7% | +66.3% | +60.5% | +53.3% |
Quarterly Operating Margin Highs
| Period | High | Date | Current |
|---|---|---|---|
| 1Y | 30.93% | -254.3% | |
| 3Y | 30.93% | -254.3% | |
| 5Y | 50.23% | -195.0% | |
| All | 52.80% | -190.4% |
Quarterly Operating Margin Lows
| Period | Low | Date | Current |
|---|---|---|---|
| 1Y | -111.59% | N/A | +57.2% |
| 3Y | -125.12% | +61.9% | |
| 5Y | -136.84% | +65.1% | |
| All | -1,233.33% | +96.1% |
Quarterly Operating Margin History
FAQ
What is the current quarterly operating margin of IONS?
As of today, IONS quarterly operating margin is -47.72%
What is IONS quarterly operating margin most recent change?
IONS quarterly operating margin was up +54.94% on March 31, 2026
What is 1-year change in IONS quarterly operating margin?
IONS quarterly operating margin is up +57.24% year-over-year
How far is IONS quarterly operating margin from its all-time high?
IONS quarterly operating margin is currently -190.38% below its historical high of 52.80% set on December 31, 2019
How does IONS quarterly operating margin rank versus sector peers?
IONS quarterly operating margin is higher than 43.54% of companies in Healthcare sector
When is IONS next earnings release?
The next earnings release for IONS is on
Operating Margin Formula
Operating Profit Margin = Operating Profit
Revenue × 100%
Revenue × 100%
Data Sources & References
- IONS Official Website www.ionis.com
- Most Recent Annual Report (10-K) www.sec.gov/Archives/edgar/data/874015/000087401526000115/0000874015-26-000115-index.htm
- IONS Profile on Yahoo Finance finance.yahoo.com/quote/IONS
- IONS Profile on NASDAQ.com www.nasdaq.com/market-activity/stocks/ions