Annual Gross Profit
$928.00M$256.07M+38.11%
Summary
- Current Value
- As of today, IONS annual gross profit is $928.00M, up +38.11% on
- Historical Performance
- IONS annual gross profit is up +68.38% over the past 3 years, up +32.54% over the past 5 years
- All-Time High Comparison
- IONS annual gross profit is currently -15.81% below its historical high of $1.10B set on
- 3-Year Low Comparison
- IONS annual gross profit is +68.38% above its 3-year low of $551.15M reached on an earlier date
- Sector Comparison
- IONS annual gross profit is higher than 90.21% of companies in Healthcare sector
Gross Profit Chart
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Series
SUGGESTED SERIES
Performance
| Metric | Date | Value | 1Y | 3Y | 5Y | 15Y |
|---|---|---|---|---|---|---|
| Annual Gross Profit | $928.00M | +38.1% | +68.4% | +32.5% | +100.0% | |
| Quarterly Gross Profit | $195.00M | -10.4% | +38.3% | -31.0% | +100.0% | |
| TTM Gross Profit | $916.29M | +36.3% | +66.3% | +30.9% | +100.0% | |
| Price | $81.15 | +158.8% | +124.1% | +54.9% | +793.7% | |
| Annual Revenue | $944.00M | +33.9% | +60.7% | +29.4% | +770.3% | |
| PE Ratio | - | – | – | – | – | |
| Annual EPS | -$2.38 | +21.6% | -25.2% | +25.2% | -284.1% | |
| $16.00M | -51.8% | -55.8% | -45.0% | – | ||
| Annual Gross Margin | 98.31% | +3.2% | +4.8% | +2.4% | +100.0% |
Gross Profit Highs
| Period | High | Date | Current |
|---|---|---|---|
| 3Y | $928.00M | at high | |
| 5Y | $928.00M | at high | |
| All | $1.10B | -15.8% |
Gross Profit Lows
| Period | Low | Date | Current |
|---|---|---|---|
| 3Y | $551.15M | N/A | +68.4% |
| 5Y | $551.15M | +68.4% | |
| All | -$2.40M | >+9999.0% |
Gross Profit History
FAQ
What is the current annual gross profit of IONS?
As of today, IONS annual gross profit is $928.00M
What is 1-year change in IONS annual gross profit?
IONS annual gross profit is up +38.11% year-over-year
What is 3-year change in IONS annual gross profit?
IONS annual gross profit is up +68.38% over the past 3 years
How far is IONS annual gross profit from its all-time high?
IONS annual gross profit is currently -15.81% below its historical high of $1.10B set on December 31, 2019
How does IONS annual gross profit rank versus sector peers?
IONS annual gross profit is higher than 90.21% of companies in Healthcare sector
When is IONS next annual earnings release?
As of today, the next annual earnings release for IONS has not been scheduled
Quarterly Gross Profit
$195.00M$43.50M+28.71%
Summary
- Current Value
- As of today, IONS quarterly gross profit is $195.00M, up +28.71% on
- Historical Performance
- IONS quarterly gross profit is down -10.44% year-over-year, up +38.33% over the past 3 years
- All-Time High Comparison
- IONS quarterly gross profit is currently -60.09% below its historical high of $488.59M set on
- 3-Year Low Comparison
- IONS quarterly gross profit is +74.58% above its 3-year low of $111.70M reached on
- Sector Comparison
- IONS quarterly gross profit is higher than 88.45% of companies in Healthcare sector
Performance
| Metric | Date | Value | 3M | 1Y | 3Y | 5Y |
|---|---|---|---|---|---|---|
| Quarterly Gross Profit | $195.00M | +28.7% | -10.4% | +38.3% | -31.0% | |
| Annual Gross Profit | $928.00M | – | +38.1% | +68.4% | +32.5% | |
| TTM Gross Profit | $916.29M | -2.4% | +36.3% | +66.3% | +30.9% | |
| Price | $81.15 | -1.9% | +158.8% | +124.1% | +54.9% | |
| Quarterly Revenue | $203.00M | +29.5% | -10.6% | +33.5% | -30.0% | |
| PE Ratio | - | – | – | – | – | |
| Quarterly EPS | -$1.41 | -75.6% | -114.8% | -286.0% | +44.3% | |
| $8.00M | +53.4% | -13.7% | -27.5% | +5.8% | ||
| Quarterly Gross Margin | 96.06% | -0.6% | +0.1% | +3.6% | -1.4% |
Quarterly Gross Profit Highs
| Period | High | Date | Current |
|---|---|---|---|
| 1Y | $445.03M | -56.2% | |
| 3Y | $445.03M | -56.2% | |
| 5Y | $445.03M | -56.2% | |
| All | $488.59M | -60.1% |
Quarterly Gross Profit Lows
| Period | Low | Date | Current |
|---|---|---|---|
| 1Y | $124.75M | +56.3% | |
| 3Y | $111.70M | +74.6% | |
| 5Y | $104.17M | +87.2% | |
| All | -$19.13M | +1119.4% |
Quarterly Gross Profit History
FAQ
What is the current quarterly gross profit of IONS?
As of today, IONS quarterly gross profit is $195.00M
What is IONS quarterly gross profit most recent change?
IONS quarterly gross profit was up +28.71% on December 31, 2025
What is 1-year change in IONS quarterly gross profit?
IONS quarterly gross profit is down -10.44% year-over-year
How far is IONS quarterly gross profit from its all-time high?
IONS quarterly gross profit is currently -60.09% below its historical high of $488.59M set on December 31, 2019
How does IONS quarterly gross profit rank versus sector peers?
IONS quarterly gross profit is higher than 88.45% of companies in Healthcare sector
When is IONS next earnings release?
The next earnings release for IONS is on
TTM Gross Profit
$916.29M$22.73M-2.42%
Summary
- Current Value
- As of today, IONS TTM gross profit is $916.29M, down -2.42% on
- Historical Performance
- IONS TTM gross profit is up +36.32% year-over-year, up +66.31% over the past 3 years
- All-Time High Comparison
- IONS TTM gross profit is currently -16.95% below its historical high of $1.10B set on
- 3-Year Low Comparison
- IONS TTM gross profit is +69.16% above its 3-year low of $541.66M reached on
- Sector Comparison
- IONS TTM gross profit is higher than 89.17% of companies in Healthcare sector
Performance
| Metric | Date | Value | 3M | 1Y | 3Y | 5Y |
|---|---|---|---|---|---|---|
| TTM Gross Profit | $916.29M | -2.4% | +36.3% | +66.3% | +30.9% | |
| Annual Gross Profit | $928.00M | – | +38.1% | +68.4% | +32.5% | |
| Quarterly Gross Profit | $195.00M | +28.7% | -10.4% | +38.3% | -31.0% | |
| Price | $81.15 | -1.9% | +158.8% | +124.1% | +54.9% | |
| TTM Revenue | $943.38M | -2.5% | +33.7% | +60.6% | +29.4% | |
| PE Ratio | - | – | – | – | – | |
| TTM EPS | -$2.47 | -44.1% | +18.8% | -29.9% | +22.4% | |
| $27.09M | -4.5% | -18.8% | -25.9% | -6.0% | ||
| Quarterly Gross Margin | 96.06% | -0.6% | +0.1% | +3.6% | -1.4% |
TTM Gross Profit Highs
| Period | High | Date | Current |
|---|---|---|---|
| 1Y | $939.02M | -2.4% | |
| 3Y | $939.02M | -2.4% | |
| 5Y | $939.02M | -2.4% | |
| All | $1.10B | -16.9% |
TTM Gross Profit Lows
| Period | Low | Date | Current |
|---|---|---|---|
| 1Y | $672.19M | N/A | +36.3% |
| 3Y | $541.66M | +69.2% | |
| 5Y | $541.66M | +69.2% | |
| All | -$56.63M | +1718.0% |
TTM Gross Profit History
FAQ
What is the current TTM gross profit of IONS?
As of today, IONS TTM gross profit is $916.29M
What is IONS TTM gross profit most recent change?
IONS TTM gross profit was down -2.42% on December 31, 2025
What is 1-year change in IONS TTM gross profit?
IONS TTM gross profit is up +36.32% year-over-year
How far is IONS TTM gross profit from its all-time high?
IONS TTM gross profit is currently -16.95% below its historical high of $1.10B set on December 31, 2019
How does IONS TTM gross profit rank versus sector peers?
IONS TTM gross profit is higher than 89.17% of companies in Healthcare sector
When is IONS next earnings release?
The next earnings release for IONS is on
Gross Profit Formula
Gross Profit = Revenue −
Data Sources & References
- IONS Official Website www.ionis.com
- Most Recent Quarterly Report (10-Q) www.sec.gov/Archives/edgar/data/874015/000087401526000115/0000874015-26-000115-index.htm
- Most Recent Annual Report (10-K) www.sec.gov/Archives/edgar/data/874015/000087401526000115/0000874015-26-000115-index.htm
- IONS Profile on Yahoo Finance finance.yahoo.com/quote/IONS
- IONS Profile on NASDAQ.com www.nasdaq.com/market-activity/stocks/ions