Annual Gross Profit
$671.93M$84.08M-11.12%
Summary
- Current Value
- As of today, IONS annual gross profit is $671.93M, down -11.12% on
- Historical Performance
- IONS annual gross profit is down -13.86% over the past 3 years, and down -39.04% over the past 5 years
- All-Time High Comparison
- IONS annual gross profit is currently -39.04% below its historical high of $1.10B set on
- 3-Year Low Comparison
- IONS annual gross profit is +21.92% above its 3-year low of $551.15M reached on an earlier date
- Sector Comparison
- IONS annual gross profit is higher than 88.73% of companies in Healthcare sector
Gross Profit Chart
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Series
SUGGESTED SERIES
Performance
| Metric | Date | Value | 1Y | 3Y | 5Y | 15Y |
|---|---|---|---|---|---|---|
| Annual Gross Profit | $671.93M | -11.1% | -13.9% | -39.0% | +100.0% | |
| Quarterly Gross Profit | $151.51M | +19.1% | -1.1% | -0.7% | +100.0% | |
| TTM Gross Profit | $939.02M | +21.8% | +11.4% | +3.6% | +100.0% | |
| Price | $79.48 | +127.5% | +99.5% | +33.2% | +700.4% | |
| Annual Revenue | $705.14M | -10.5% | -13.0% | -37.2% | +479.9% | |
| PE Ratio | - | – | – | – | – | |
| Annual EPS | -$3.04 | -18.7% | -1396.9% | -246.3% | -879.3% | |
| Annual Cost Of Goods Sold | $33.21M | +5.0% | +9.2% | +63.0% | – | |
| Annual Gross Margin | 95.29% | -0.7% | -1.0% | -2.9% | +100.0% |
Gross Profit Highs
| Period | High | Date | Current |
|---|---|---|---|
| 3Y | $756.02M | -11.1% | |
| 5Y | $780.05M | -13.9% | |
| All | $1.10B | -39.0% |
Gross Profit Lows
| Period | Low | Date | Current |
|---|---|---|---|
| 3Y | $551.15M | N/A | +21.9% |
| 5Y | $551.15M | +21.9% | |
| All | -$2.40M | >+9999.0% |
Gross Profit History
FAQ
What is the current annual gross profit of IONS?
As of today, IONS annual gross profit is $671.93M
What is 1-year change in IONS annual gross profit?
IONS annual gross profit is down -11.12% year-over-year
What is 3-year change in IONS annual gross profit?
IONS annual gross profit is down -13.86% over the past 3 years
How far is IONS annual gross profit from its all-time high?
IONS annual gross profit is currently -39.04% below its historical high of $1.10B set on December 31, 2019
How does IONS annual gross profit rank versus sector peers?
IONS annual gross profit is higher than 88.73% of companies in Healthcare sector
When is IONS next annual earnings release?
The next annual earnings release for IONS is on
Quarterly Gross Profit
$151.51M$293.53M-65.96%
Summary
- Current Value
- As of today, IONS quarterly gross profit is $151.51M, down -65.96% on
- Historical Performance
- IONS quarterly gross profit is up +19.06% year-over-year, and down -1.08% over the past 3 years
- All-Time High Comparison
- IONS quarterly gross profit is currently -68.99% below its historical high of $488.59M set on
- 3-Year Low Comparison
- IONS quarterly gross profit is +35.64% above its 3-year low of $111.70M reached on
- Sector Comparison
- IONS quarterly gross profit is higher than 86.99% of companies in Healthcare sector
Performance
| Metric | Date | Value | 3M | 1Y | 3Y | 5Y |
|---|---|---|---|---|---|---|
| Quarterly Gross Profit | $151.51M | -66.0% | +19.1% | -1.1% | -0.7% | |
| Annual Gross Profit | $671.93M | – | -11.1% | -13.9% | -39.0% | |
| TTM Gross Profit | $939.02M | +2.6% | +21.8% | +11.4% | +3.6% | |
| Price | $79.48 | +12.6% | +127.5% | +99.5% | +33.2% | |
| Quarterly Revenue | $156.72M | -65.3% | +17.1% | -1.9% | -2.1% | |
| PE Ratio | - | – | – | – | – | |
| Quarterly EPS | -$0.81 | -218.8% | +14.8% | -143.2% | -359.7% | |
| Quarterly Cost Of Goods Sold | $5.21M | -25.7% | -20.6% | -21.1% | -30.8% | |
| Quarterly Gross Margin | 96.67% | -1.8% | +1.7% | +0.8% | +1.4% |
Quarterly Gross Profit Highs
| Period | High | Date | Current |
|---|---|---|---|
| 1Y | $445.03M | -66.0% | |
| 3Y | $445.03M | -66.0% | |
| 5Y | $445.03M | -66.0% | |
| All | $488.59M | -69.0% |
Quarterly Gross Profit Lows
| Period | Low | Date | Current |
|---|---|---|---|
| 1Y | $124.75M | +21.4% | |
| 3Y | $111.70M | +35.6% | |
| 5Y | $104.17M | +45.4% | |
| All | -$19.13M | +892.0% |
Quarterly Gross Profit History
FAQ
What is the current quarterly gross profit of IONS?
As of today, IONS quarterly gross profit is $151.51M
What is IONS quarterly gross profit most recent change?
IONS quarterly gross profit was down -65.96% on September 1, 2025
What is 1-year change in IONS quarterly gross profit?
IONS quarterly gross profit is up +19.06% year-over-year
How far is IONS quarterly gross profit from its all-time high?
IONS quarterly gross profit is currently -68.99% below its historical high of $488.59M set on December 31, 2019
How does IONS quarterly gross profit rank versus sector peers?
IONS quarterly gross profit is higher than 86.99% of companies in Healthcare sector
When is IONS next earnings release?
The next earnings release for IONS is on
TTM Gross Profit
$939.02M$24.26M+2.65%
Summary
- Current Value
- As of today, IONS TTM gross profit is $939.02M, up +2.65% on
- Historical Performance
- IONS TTM gross profit is up +21.82% year-over-year, and up +11.39% over the past 3 years
- All-Time High Comparison
- IONS TTM gross profit is currently -14.89% below its historical high of $1.10B set on
- 3-Year Low Comparison
- IONS TTM gross profit is +73.36% above its 3-year low of $541.66M reached on
- Sector Comparison
- IONS TTM gross profit is higher than 89.70% of companies in Healthcare sector
Performance
| Metric | Date | Value | 3M | 1Y | 3Y | 5Y |
|---|---|---|---|---|---|---|
| TTM Gross Profit | $939.02M | +2.6% | +21.8% | +11.4% | +3.6% | |
| Annual Gross Profit | $671.93M | – | -11.1% | -13.9% | -39.0% | |
| Quarterly Gross Profit | $151.51M | -66.0% | +19.1% | -1.1% | -0.7% | |
| Price | $79.48 | +12.6% | +127.5% | +99.5% | +33.2% | |
| TTM Revenue | $967.38M | +2.4% | +20.4% | +10.5% | +3.7% | |
| PE Ratio | - | – | – | – | – | |
| TTM EPS | -$1.71 | +7.6% | +29.9% | -1233.8% | -406.7% | |
| TTM Cost Of Goods Sold | $28.36M | -4.5% | -13.3% | -12.7% | +7.7% | |
| Quarterly Gross Margin | 96.67% | -1.8% | +1.7% | +0.8% | +1.4% |
TTM Gross Profit Highs
| Period | High | Date | Current |
|---|---|---|---|
| 1Y | $939.02M | at high | |
| 3Y | $939.02M | at high | |
| 5Y | $939.02M | at high | |
| All | $1.10B | -14.9% |
TTM Gross Profit Lows
| Period | Low | Date | Current |
|---|---|---|---|
| 1Y | $672.19M | N/A | +39.7% |
| 3Y | $541.66M | +73.4% | |
| 5Y | $541.66M | +73.4% | |
| All | -$56.63M | +1758.2% |
TTM Gross Profit History
FAQ
What is the current TTM gross profit of IONS?
As of today, IONS TTM gross profit is $939.02M
What is IONS TTM gross profit most recent change?
IONS TTM gross profit was up +2.65% on September 1, 2025
What is 1-year change in IONS TTM gross profit?
IONS TTM gross profit is up +21.82% year-over-year
How far is IONS TTM gross profit from its all-time high?
IONS TTM gross profit is currently -14.89% below its historical high of $1.10B set on December 31, 2019
How does IONS TTM gross profit rank versus sector peers?
IONS TTM gross profit is higher than 89.70% of companies in Healthcare sector
When is IONS next earnings release?
The next earnings release for IONS is on
Gross Profit Formula
Gross Profit = Revenue −
Data Sources & References
- IONS Official Website www.ionis.com
- Most Recent Annual Report (10-K) www.sec.gov/Archives/edgar/data/874015/000087401525000089/0000874015-25-000089-index.htm
- IONS Profile on Yahoo Finance finance.yahoo.com/quote/IONS
- IONS Profile on NASDAQ.com www.nasdaq.com/market-activity/stocks/ions