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Ionis Pharmaceuticals, Inc. (IONS) Gross profit

Annual gross profit:

$671.93M-$84.08M(-11.12%)
December 31, 2024

Summary

  • As of today (August 20, 2025), IONS annual gross profit is $671.93 million, with the most recent change of -$84.08 million (-11.12%) on December 31, 2024.
  • During the last 3 years, IONS annual gross profit has fallen by -$108.12 million (-13.86%).
  • IONS annual gross profit is now -39.04% below its all-time high of $1.10 billion, reached on December 31, 2019.

Performance

1-year change

-11.12%

3-year change

-13.86%

5-year change

-39.04%

15-year change

+32.84%

IONS Gross profit Chart

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Highlights

Sector rank

88.94%
IONS annual gross profit is higher than 88.94% of companies in Healthcare sector

Range

All-time high

$1.10B
IONS annual gross profit is currently -39.04% below its historical high of $1.10 billion

3-year low

$551.15M
IONS annual gross profit is currently +21.92% above its 3-year low

Earnings dates

Last annual earnings report date

Dec 31, 2024
IONS previous annual earnings announcement was published on Dec 31, 2024

Next annual earnings report date

N/A
IONS next annual earnings announcement has not yet been scheduled

OtherIONSincome statement metrics

annual gross margin

95.29%
IONS annual gross profit margin is 95.29%

Annual revenue

$705.14M
IONS annual revenue is $705.14 million

annual net income

-$453.90M
IONS annual net profit is -$453.90 million

Annual EPS

-$3.04
IONS annual earnings per share is -$3.04

quarterly gross profit:

$445.03M+$320.28M(+256.73%)
June 30, 2025

Summary

  • As of today (August 20, 2025), IONS quarterly gross profit is $445.03 million, with the most recent change of +$320.28 million (+256.73%) on June 30, 2025.
  • Over the past year, IONS quarterly gross profit has increased by +$229.53 million (+106.51%).
  • IONS quarterly gross profit is now -8.92% below its all-time high of $488.59 million, reached on December 31, 2019.

Performance

3-month change

+256.73%

1-year change

+106.51%

3-year change

+259.01%

5-year change

+221.34%

IONS quarterly gross profit Chart

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Highlights

Sector rank

92.52%
IONS quarterly gross profit is higher than 92.52% of companies in Healthcare sector

Range

All-time high

$488.59M
IONS quarterly gross profit is currently -8.92% below its historical high of $488.59 million

3-year low

$111.69M
IONS quarterly gross profit is currently +298.44% above its 3-year low

Earnings dates

Last quarterly earnings report date

Jun 30, 2025
IONS previous earnings announcement was published on Jun 30, 2025

Next quarterly earnings report date

Nov 5, 2025
IONS next earnings announcement is scheduled for Nov 5, 2025

OtherIONSincome statement metrics

quarterly gross margin

98.45%
IONS quarterly gross profit margin is 98.45%

Quarterly revenue

$452.05M
IONS quarterly revenue is $452.05 million

quarterly net income

$123.55M
IONS quarterly net profit is $123.55 million

Quarterly EPS

$0.70
IONS quarterly earnings per share is $0.70

TTM gross profit:

$914.77M+$229.53M(+33.50%)
June 30, 2025

Summary

  • As of today (August 20, 2025), IONS TTM gross profit is $914.77 million, with the most recent change of +$229.53 million (+33.50%) on June 30, 2025.
  • Over the past year, IONS TTM gross profit has increased by +$134.75 million (+17.28%).
  • IONS TTM gross profit is now -17.08% below its all-time high of $1.10 billion, reached on December 31, 2019.

Performance

3-month change

+33.5%

1-year change

+17.28%

3-year change

+12.22%

5-year change

-0.25%

IONS TTM gross profit Chart

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Highlights

Sector rank

89.89%
IONS TTM gross profit is higher than 89.89% of companies in Healthcare sector

Range

All-time high

$1.10B
IONS TTM gross profit is currently -17.08% below its historical high of $1.10 billion

3-year low

$541.66M
IONS TTM gross profit is currently +68.88% above its 3-year low

Earnings dates

Last quarterly earnings report date

Jun 30, 2025
IONS previous earnings announcement was published on Jun 30, 2025

Next quarterly earnings report date

Nov 5, 2025
IONS next earnings announcement is scheduled for Nov 5, 2025

OtherIONSincome statement metrics

annual gross margin

95.29%
IONS annual gross profit margin is 95.29%

TTM revenue

$944.48M
IONS TTM revenue is $944.48 million

TTM net income

-$267.87M
IONS TTM net profit is -$267.87 million

TTM EPS

-$1.84
IONS TTM earnings per share is -$1.84

Gross profit Formula

Gross Profit = Revenue − Cost Of Goods Sold

Annual gross profit

$671.93M
IONS annual gross profit is $671.93 million

Annual revenue

$705.14M
IONS annual revenue is $705.14 million

annual cost of goods sold

$33.20M
IONS annual cost of goods sold is $33.20 million

IONS Gross profit Trends

PeriodPeriodAnnualAnnualQuarterlyQuarterlyTTMTTM
1 y1 year-11.1%+106.5%+17.3%
3 y3 years-13.9%+259.0%+12.2%
5 y5 years-39.0%+221.3%-0.3%

IONS Gross profit Highs & Lows

PeriodPeriodAnnual vs highAnnual vs highAnnual vs lowAnnual vs lowQuarter. vs highQuarter. vs highQuarter. vs lowQuarter. vs lowTTM vs highTTM vs highTTM vs lowTTM vs low
3 y3-year-13.9%+21.9%at high+298.4%at high+68.9%
5 y5-year-39.0%+21.9%at high+327.2%-0.3%+68.9%
alltimeall time-39.0%>+9999.0%-8.9%+2426.5%-17.1%+1715.3%

IONS Gross profit History

DateAnnualQuarterlyTTM
Jun 2025
-
$445.03M(+256.7%)
$914.77M(+33.5%)
Mar 2025
-
$124.75M(-42.7%)
$685.24M(+1.9%)
Dec 2024
$671.93M(-11.1%)
$217.73M(+71.1%)
$672.18M(-12.8%)
Sep 2024
-
$127.25M(-41.0%)
$770.84M(-1.2%)
Jun 2024
-
$215.51M(+92.9%)
$780.01M(+4.7%)
Mar 2024
-
$111.69M(-64.7%)
$744.69M(-1.6%)
Dec 2023
$756.02M(+37.2%)
$316.39M(+131.9%)
$756.57M(+30.2%)
Sep 2023
-
$136.43M(-24.3%)
$581.16M(-2.8%)
Jun 2023
-
$180.19M(+45.8%)
$597.89M(+10.4%)
Mar 2023
-
$123.58M(-12.3%)
$541.66M(-1.7%)
Dec 2022
$551.15M(-29.3%)
$140.97M(-8.0%)
$550.94M(-34.6%)
Sep 2022
-
$153.16M(+23.6%)
$842.99M(+3.4%)
Jun 2022
-
$123.96M(-6.7%)
$815.14M(+0.8%)
Mar 2022
-
$132.85M(-69.3%)
$808.96M(+3.7%)
Dec 2021
$780.05M(+11.4%)
$433.02M(+245.6%)
$780.27M(+23.9%)
Sep 2021
-
$125.31M(+6.4%)
$629.69M(-4.1%)
Jun 2021
-
$117.78M(+13.1%)
$656.93M(-3.1%)
Mar 2021
-
$104.17M(-63.1%)
$677.64M(-3.2%)
Dec 2020
$700.16M(-36.5%)
$282.44M(+85.2%)
$700.18M(-22.7%)
Sep 2020
-
$152.54M(+10.1%)
$906.34M(-1.2%)
Jun 2020
-
$138.49M(+9.3%)
$917.04M(-2.2%)
Mar 2020
-
$126.71M(-74.1%)
$937.34M(-15.0%)
Dec 2019
$1.10B(+88.3%)
$488.59M(+199.3%)
$1.10B(+37.5%)
Sep 2019
-
$163.24M(+2.8%)
$802.48M(+25.5%)
Jun 2019
-
$158.79M(-45.7%)
$639.24M(+33.1%)
Mar 2019
-
$292.63M(+55.8%)
$480.44M(+155.8%)
Dec 2018
$585.33M(+15.7%)
$187.81M(>+9900.0%)
$187.81M(+9.6%)
Sep 2018
-
$0.00(0.0%)
$171.30M(0.0%)
Jun 2018
-
$0.00(0.0%)
$171.30M(0.0%)
Mar 2018
-
$0.00(-100.0%)
$171.30M(0.0%)
Dec 2017
$505.83M(>+9900.0%)
$171.30M(>+9900.0%)
$171.30M(>+9900.0%)
Sep 2017
-
$0.00(0.0%)
$0.00(0.0%)
Jun 2017
-
$0.00(0.0%)
$0.00(0.0%)
Mar 2017
-
$0.00(0.0%)
$0.00(0.0%)
Dec 2016
$0.00(0.0%)
$0.00(0.0%)
$0.00(0.0%)
Sep 2016
-
$0.00(0.0%)
$0.00(0.0%)
Jun 2016
-
$0.00(0.0%)
$0.00(0.0%)
Mar 2016
-
$0.00(0.0%)
$0.00(0.0%)
Dec 2015
$0.00(0.0%)
$0.00(0.0%)
$0.00(0.0%)
Sep 2015
-
$0.00(0.0%)
$0.00(0.0%)
Jun 2015
-
$0.00(0.0%)
$0.00(0.0%)
Mar 2015
-
$0.00(0.0%)
$0.00(0.0%)
Dec 2014
$0.00(0.0%)
$0.00(0.0%)
$0.00(0.0%)
Sep 2014
-
$0.00(0.0%)
$0.00(0.0%)
Jun 2014
-
$0.00(0.0%)
$0.00(0.0%)
Mar 2014
-
$0.00(0.0%)
$0.00(0.0%)
Dec 2013
$0.00(0.0%)
$0.00(0.0%)
$0.00(0.0%)
Sep 2013
-
$0.00(0.0%)
$0.00(0.0%)
Jun 2013
-
$0.00(0.0%)
$0.00(0.0%)
Mar 2013
-
$0.00(0.0%)
$0.00(0.0%)
Dec 2012
$0.00(0.0%)
$0.00(0.0%)
$0.00(-100.0%)
Sep 2012
-
$0.00(0.0%)
-$13.80M(-58.1%)
Jun 2012
-
$0.00(0.0%)
-$32.93M(-25.4%)
Mar 2012
-
$0.00(-100.0%)
-$44.11M(-22.1%)
Dec 2011
$0.00(0.0%)
-$13.80M(-27.9%)
-$56.63M(+32.2%)
Sep 2011
-
-$19.13M(+71.0%)
-$42.83M(+80.7%)
Jun 2011
-
-$11.19M(-10.6%)
-$23.70M(+89.4%)
Mar 2011
-
-$12.52M(<-9900.0%)
-$12.52M(<-9900.0%)
Dec 2010
$0.00(0.0%)
$0.00(0.0%)
$0.00(0.0%)
Sep 2010
-
$0.00(0.0%)
$0.00(0.0%)
Jun 2010
-
$0.00(0.0%)
$0.00(0.0%)
Mar 2010
-
$0.00(0.0%)
$0.00(0.0%)
DateAnnualQuarterlyTTM
Dec 2009
$0.00(0.0%)
$0.00(0.0%)
$0.00(0.0%)
Sep 2009
-
$0.00(0.0%)
$0.00(0.0%)
Jun 2009
-
$0.00(0.0%)
$0.00(0.0%)
Mar 2009
-
$0.00(0.0%)
$0.00(0.0%)
Dec 2008
$0.00(0.0%)
$0.00(0.0%)
$0.00(0.0%)
Sep 2008
-
$0.00(0.0%)
$0.00(0.0%)
Jun 2008
-
$0.00(0.0%)
$0.00(0.0%)
Mar 2008
-
$0.00(0.0%)
$0.00(0.0%)
Dec 2007
$0.00(0.0%)
$0.00(0.0%)
$0.00(0.0%)
Sep 2007
-
$0.00(0.0%)
$0.00(0.0%)
Jun 2007
-
$0.00(0.0%)
$0.00(0.0%)
Mar 2007
-
$0.00(0.0%)
$0.00(0.0%)
Dec 2006
$0.00(0.0%)
$0.00(0.0%)
$0.00(0.0%)
Sep 2006
-
$0.00(0.0%)
$0.00(0.0%)
Jun 2006
-
$0.00(0.0%)
$0.00(0.0%)
Mar 2006
-
$0.00(0.0%)
$0.00(0.0%)
Dec 2005
$0.00(0.0%)
$0.00(0.0%)
$0.00(0.0%)
Sep 2005
-
$0.00(0.0%)
$0.00(0.0%)
Jun 2005
-
$0.00(0.0%)
$0.00(0.0%)
Mar 2005
-
$0.00(0.0%)
$0.00(0.0%)
Dec 2004
$0.00(0.0%)
$0.00(0.0%)
$0.00(0.0%)
Sep 2004
-
$0.00(0.0%)
$0.00(0.0%)
Jun 2004
-
$0.00(0.0%)
$0.00(0.0%)
Mar 2004
-
$0.00(0.0%)
$0.00(0.0%)
Dec 2003
$0.00(0.0%)
$0.00(0.0%)
$0.00(0.0%)
Sep 2003
-
$0.00(0.0%)
$0.00(0.0%)
Jun 2003
-
$0.00(0.0%)
$0.00(0.0%)
Mar 2003
-
$0.00(0.0%)
$0.00(0.0%)
Dec 2002
$0.00(0.0%)
$0.00(0.0%)
$0.00(0.0%)
Sep 2002
-
$0.00(0.0%)
$0.00(0.0%)
Jun 2002
-
$0.00(0.0%)
$0.00(0.0%)
Mar 2002
-
$0.00(0.0%)
$0.00(0.0%)
Dec 2001
$0.00(0.0%)
$0.00(0.0%)
$0.00(0.0%)
Sep 2001
-
$0.00(0.0%)
$0.00(0.0%)
Jun 2001
-
$0.00(0.0%)
$0.00(0.0%)
Mar 2001
-
$0.00(0.0%)
$0.00(0.0%)
Dec 2000
$0.00(0.0%)
$0.00(0.0%)
$0.00(0.0%)
Sep 2000
-
$0.00(0.0%)
$0.00(0.0%)
Jun 2000
-
$0.00(0.0%)
$0.00(0.0%)
Mar 2000
-
$0.00(0.0%)
$0.00(0.0%)
Dec 1999
$0.00(0.0%)
$0.00(0.0%)
$0.00(0.0%)
Sep 1999
-
$0.00(0.0%)
$0.00(0.0%)
Jun 1999
-
$0.00(0.0%)
$0.00(0.0%)
Mar 1999
-
$0.00(0.0%)
$0.00(0.0%)
Dec 1998
$0.00(0.0%)
$0.00(0.0%)
$0.00(0.0%)
Sep 1998
-
$0.00(0.0%)
$0.00(0.0%)
Jun 1998
-
$0.00(0.0%)
$0.00(0.0%)
Mar 1998
-
$0.00(-100.0%)
$0.00(-100.0%)
Dec 1997
$0.00(0.0%)
-
-
Dec 1996
$0.00(0.0%)
-
-
Dec 1995
$0.00(0.0%)
-
-
Dec 1994
$0.00(0.0%)
-
-
Dec 1993
$0.00(0.0%)
-
-
Dec 1992
$0.00(0.0%)
$18.80M(-726.7%)
$10.50M(-190.5%)
Sep 1992
-
-$3.00M(+30.4%)
-$11.60M(+18.4%)
Jun 1992
-
-$2.30M(-23.3%)
-$9.80M(+69.0%)
Mar 1992
-
-$3.00M(-9.1%)
-$5.80M(+81.3%)
Dec 1991
$0.00(-100.0%)
-$3.30M(+175.0%)
-$3.20M(-3300.0%)
Sep 1991
-
-$1.20M(-170.6%)
$100.00K(-92.3%)
Jun 1991
-
$1.70M(-525.0%)
$1.30M(-425.0%)
Mar 1991
-
-$400.00K
-$400.00K
Dec 1990
-$2.40M
-
-

FAQ

  • What is Ionis Pharmaceuticals, Inc. annual gross profit?
  • What is the all time high annual gross profit for Ionis Pharmaceuticals, Inc.?
  • What is Ionis Pharmaceuticals, Inc. annual gross profit year-on-year change?
  • What is Ionis Pharmaceuticals, Inc. quarterly gross profit?
  • What is the all time high quarterly gross profit for Ionis Pharmaceuticals, Inc.?
  • What is Ionis Pharmaceuticals, Inc. quarterly gross profit year-on-year change?
  • What is Ionis Pharmaceuticals, Inc. TTM gross profit?
  • What is the all time high TTM gross profit for Ionis Pharmaceuticals, Inc.?
  • What is Ionis Pharmaceuticals, Inc. TTM gross profit year-on-year change?

What is Ionis Pharmaceuticals, Inc. annual gross profit?

The current annual gross profit of IONS is $671.93M

What is the all time high annual gross profit for Ionis Pharmaceuticals, Inc.?

Ionis Pharmaceuticals, Inc. all-time high annual gross profit is $1.10B

What is Ionis Pharmaceuticals, Inc. annual gross profit year-on-year change?

Over the past year, IONS annual gross profit has changed by -$84.08M (-11.12%)

What is Ionis Pharmaceuticals, Inc. quarterly gross profit?

The current quarterly gross profit of IONS is $445.03M

What is the all time high quarterly gross profit for Ionis Pharmaceuticals, Inc.?

Ionis Pharmaceuticals, Inc. all-time high quarterly gross profit is $488.59M

What is Ionis Pharmaceuticals, Inc. quarterly gross profit year-on-year change?

Over the past year, IONS quarterly gross profit has changed by +$229.53M (+106.51%)

What is Ionis Pharmaceuticals, Inc. TTM gross profit?

The current TTM gross profit of IONS is $914.77M

What is the all time high TTM gross profit for Ionis Pharmaceuticals, Inc.?

Ionis Pharmaceuticals, Inc. all-time high TTM gross profit is $1.10B

What is Ionis Pharmaceuticals, Inc. TTM gross profit year-on-year change?

Over the past year, IONS TTM gross profit has changed by +$134.75M (+17.28%)
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