Annual Gross Profit
$928.00M$256.07M+38.11%
Summary
- Current Value
- As of today, IONS annual gross profit is $928.00M, up +38.11% on
- Historical Performance
- IONS annual gross profit is up +68.38% over the past 3 years, up +32.54% over the past 5 years
- All-Time High Comparison
- IONS annual gross profit is currently -15.81% below its historical high of $1.10B set on
- 3-Year Low Comparison
- IONS annual gross profit is +68.38% above its 3-year low of $551.15M reached on an earlier date
- Sector Comparison
- IONS annual gross profit is higher than 90.55% of companies in Healthcare sector
Gross Profit Chart
SUGGESTED SERIES
Performance
| Metric | Date | Value | 1Y | 3Y | 5Y | 15Y |
|---|---|---|---|---|---|---|
| Annual Gross Profit | $928.00M | +38.1% | +68.4% | +32.5% | +100.0% | |
| Quarterly Gross Profit | $235.66M | +88.9% | +90.7% | +126.2% | +1982.9% | |
| TTM Gross Profit | $1.02B | +49.3% | +88.9% | +51.0% | +8276.0% | |
| Price | $74.48 | +111.3% | +76.2% | +115.6% | +747.3% | |
| Annual Revenue | $943.71M | +33.8% | +60.7% | +29.4% | +770.0% | |
| PE Ratio | - | – | – | – | – | |
| Annual EPS | -$2.38 | +21.5% | -25.4% | +25.1% | -284.4% | |
| $28.36M | -14.6% | -21.7% | -2.6% | – | ||
| Annual Gross Margin | 98.31% | +3.2% | +4.8% | +2.4% | +100.0% |
Gross Profit Highs
| Period | High | Date | Current |
|---|---|---|---|
| 3Y | $928.00M | at high | |
| 5Y | $928.00M | at high | |
| All | $1.10B | -15.8% |
Gross Profit Lows
| Period | Low | Date | Current |
|---|---|---|---|
| 3Y | $551.15M | N/A | +68.4% |
| 5Y | $551.15M | +68.4% | |
| All | -$2.40M | >+9999.0% |
Gross Profit History
FAQ
What is the current annual gross profit of IONS?
As of today, IONS annual gross profit is $928.00M
What is 1-year change in IONS annual gross profit?
IONS annual gross profit is up +38.11% year-over-year
What is 3-year change in IONS annual gross profit?
IONS annual gross profit is up +68.38% over the past 3 years
How far is IONS annual gross profit from its all-time high?
IONS annual gross profit is currently -15.81% below its historical high of $1.10B set on December 31, 2019
How does IONS annual gross profit rank versus sector peers?
IONS annual gross profit is higher than 90.55% of companies in Healthcare sector
When is IONS next annual earnings release?
As of today, the next annual earnings release for IONS has not been scheduled
Gross Profit Formula
Gross Profit = Revenue −
Quarterly Gross Profit
$235.66M$44.56M+23.32%
Summary
- Current Value
- As of today, IONS quarterly gross profit is $235.66M, up +23.32% on
- Historical Performance
- IONS quarterly gross profit is up +88.90% year-over-year, up +90.70% over the past 3 years
- All-Time High Comparison
- IONS quarterly gross profit is currently -51.77% below its historical high of $488.59M set on
- 3-Year Low Comparison
- IONS quarterly gross profit is +110.99% above its 3-year low of $111.70M reached on
- Sector Comparison
- IONS quarterly gross profit is higher than 89.62% of companies in Healthcare sector
Performance
| Metric | Date | Value | 3M | 1Y | 3Y | 5Y |
|---|---|---|---|---|---|---|
| Quarterly Gross Profit | $235.66M | +23.3% | +88.9% | +90.7% | +126.2% | |
| Annual Gross Profit | $928.00M | – | +38.1% | +68.4% | +32.5% | |
| TTM Gross Profit | $1.02B | +12.2% | +49.3% | +88.9% | +51.0% | |
| Price | $74.48 | -0.9% | +111.3% | +76.2% | +115.6% | |
| Quarterly Revenue | $246.09M | +21.2% | +87.0% | +88.5% | +120.5% | |
| PE Ratio | - | – | – | – | – | |
| Quarterly EPS | -$0.56 | +60.3% | +39.4% | +35.6% | +12.1% | |
| $10.43M | -12.3% | +52.0% | +50.1% | +40.3% | ||
| Quarterly Gross Margin | 95.76% | +1.7% | +1.0% | +1.1% | +2.6% |
Quarterly Gross Profit Highs
| Period | High | Date | Current |
|---|---|---|---|
| 1Y | $445.03M | -47.0% | |
| 3Y | $445.03M | -47.0% | |
| 5Y | $445.03M | -47.0% | |
| All | $488.59M | -51.8% |
Quarterly Gross Profit Lows
| Period | Low | Date | Current |
|---|---|---|---|
| 1Y | $124.75M | N/A | +88.9% |
| 3Y | $111.70M | +111.0% | |
| 5Y | $104.17M | N/A | +126.2% |
| All | -$19.13M | +1332.0% |
Quarterly Gross Profit History
FAQ
What is the current quarterly gross profit of IONS?
As of today, IONS quarterly gross profit is $235.66M
What is IONS quarterly gross profit most recent change?
IONS quarterly gross profit was up +23.32% on March 31, 2026
What is 1-year change in IONS quarterly gross profit?
IONS quarterly gross profit is up +88.90% year-over-year
How far is IONS quarterly gross profit from its all-time high?
IONS quarterly gross profit is currently -51.77% below its historical high of $488.59M set on December 31, 2019
How does IONS quarterly gross profit rank versus sector peers?
IONS quarterly gross profit is higher than 89.62% of companies in Healthcare sector
When is IONS next earnings release?
The next earnings release for IONS is on
Gross Profit Formula
Gross Profit = Revenue −
TTM Gross Profit
$1.02B$110.91M+12.16%
Summary
- Current Value
- As of today, IONS TTM gross profit is $1.02B, up +12.16% on
- Historical Performance
- IONS TTM gross profit is up +49.33% year-over-year, up +88.92% over the past 3 years
- All-Time High Comparison
- IONS TTM gross profit is currently -7.25% below its historical high of $1.10B set on
- 3-Year Low Comparison
- IONS TTM gross profit is +88.92% above its 3-year low of $541.66M reached on an earlier date
- Sector Comparison
- IONS TTM gross profit is higher than 90.27% of companies in Healthcare sector
Performance
| Metric | Date | Value | 3M | 1Y | 3Y | 5Y |
|---|---|---|---|---|---|---|
| TTM Gross Profit | $1.02B | +12.2% | +49.3% | +88.9% | +51.0% | |
| Annual Gross Profit | $928.00M | – | +38.1% | +68.4% | +32.5% | |
| Quarterly Gross Profit | $235.66M | +23.3% | +88.9% | +90.7% | +126.2% | |
| Price | $74.48 | -0.9% | +111.3% | +76.2% | +115.6% | |
| TTM Revenue | $1.06B | +12.1% | +47.4% | +83.6% | +49.6% | |
| PE Ratio | - | – | – | – | – | |
| TTM EPS | -$2.10 | +14.8% | +29.5% | +9.0% | +40.5% | |
| $34.56M | +11.5% | +6.5% | +0.4% | +16.8% | ||
| Quarterly Gross Margin | 95.76% | +1.7% | +1.0% | +1.1% | +2.6% |
TTM Gross Profit Highs
| Period | High | Date | Current |
|---|---|---|---|
| 1Y | $1.02B | at high | |
| 3Y | $1.02B | at high | |
| 5Y | $1.02B | at high | |
| All | $1.10B | -7.3% |
TTM Gross Profit Lows
| Period | Low | Date | Current |
|---|---|---|---|
| 1Y | $685.24M | N/A | +49.3% |
| 3Y | $541.66M | N/A | +88.9% |
| 5Y | $541.66M | +88.9% | |
| All | -$56.63M | +1907.0% |
TTM Gross Profit History
FAQ
What is the current TTM gross profit of IONS?
As of today, IONS TTM gross profit is $1.02B
What is IONS TTM gross profit most recent change?
IONS TTM gross profit was up +12.16% on March 31, 2026
What is 1-year change in IONS TTM gross profit?
IONS TTM gross profit is up +49.33% year-over-year
How far is IONS TTM gross profit from its all-time high?
IONS TTM gross profit is currently -7.25% below its historical high of $1.10B set on December 31, 2019
How does IONS TTM gross profit rank versus sector peers?
IONS TTM gross profit is higher than 90.27% of companies in Healthcare sector
When is IONS next earnings release?
The next earnings release for IONS is on
Gross Profit Formula
Gross Profit = Revenue −
Data Sources & References
- IONS Official Website www.ionis.com
- Most Recent Annual Report (10-K) www.sec.gov/Archives/edgar/data/874015/000087401526000115/0000874015-26-000115-index.htm
- IONS Profile on Yahoo Finance finance.yahoo.com/quote/IONS
- IONS Profile on NASDAQ.com www.nasdaq.com/market-activity/stocks/ions