What is the current 10-day volatility of IONS?

As of today, IONS 10-day volatility is 54.99%

What 10-day volatility category does IONS fall into?

Based on its current 10-day historical volatility, IONS falls into the high volatility category

What is IONS 10-day volatility 1-year high?

IONS 10-day volatility reached a 1-year high of 134.22% on July 10, 2026

What is IONS 10-day volatility 1-year low?

IONS 10-day volatility reached a 1-year low of 10.35% on October 20, 2025

What is the current 1-month volatility of IONS?

As of today, IONS 1-month volatility is 51.38%

What 1-month volatility category does IONS fall into?

Based on its current 1-month historical volatility, IONS falls into the high volatility category

What is IONS 1-month volatility 1-year high?

IONS 1-month volatility reached a 1-year high of 127.70% on September 19, 2025

What is IONS 1-month volatility 1-year low?

IONS 1-month volatility reached a 1-year low of 18.28% on October 20, 2025

What is the current 3-month volatility of IONS?

As of today, IONS 3-month volatility is 66.12%

What 3-month volatility category does IONS fall into?

Based on its current 3-month historical volatility, IONS falls into the extreme volatility category

What is IONS 3-month volatility 1-year high?

IONS 3-month volatility reached a 1-year high of 78.44% on September 19, 2025

What is IONS 3-month volatility 1-year low?

IONS 3-month volatility reached a 1-year low of 24.02% on July 1, 2026

What is the current 1-year volatility of IONS?

As of today, IONS 1-year volatility is 41.82%

What 1-year volatility category does IONS fall into?

Based on its current 1-year historical volatility, IONS falls into the high volatility category

What is IONS 1-year volatility 1-year high?

IONS 1-year volatility reached a 1-year high of 53.73% on November 14, 2025

What is IONS 1-year volatility 1-year low?

IONS 1-year volatility reached a 1-year low of 39.87% on September 9, 2026

IONS Stock Volatility History & Chart Since 1991

10-Day

54.99%

September 18, 2026

Summary

Current Value: As of today, IONS 10-day volatility is 54.99%, down -0.63% on September 18, 2026
Value Category: Based on its current 10-day historical volatility, IONS falls into the high volatility category
1-Year High: IONS 10-day volatility reached a 1-year high of 134.22% on July 10, 2026
1-Year Low: IONS 10-day volatility reached a 1-year low of 10.35% on October 20, 2025

10-Day Volatility Chart

Performance

IONS Performance
Metric	Date	Value	1D	1M	3M	YTD	1Y	3Y	5Y
10-Day Volatility	Sep 18, 26	54.99%	-0.6%	+67.8%	+186.8%	+142.1%	+42.2%	+53.3%	+60.8%
1-Month Volatility	Sep 18, 26	51.38%	+1.4%	+41.8%	+134.4%	+130.4%	-57.9%	+95.0%	+59.2%
3-Month Volatility	Sep 18, 26	66.12%	+0.8%	+10.0%	+162.6%	+120.5%	-15.6%	+147.1%	+109.4%
1-Year Volatility	Sep 18, 26	41.82%	+0.8%	-21.0%	-10.4%	-20.3%	-21.8%	+23.1%	-3.1%
14-Day RSI	Sep 18, 26	25.37	-10.0%	-52.0%	-47.7%	-50.8%	-65.1%	-59.4%	-44.9%
Beta	Sep 18, 26	0.45	+2.3%	+150.0%	+7.1%	-37.5%	-43.8%	-19.6%	-54.1%
ATR	Sep 18, 26	$2.50	-0.1%	+11.2%	+17.9%	+22.4%	+18.5%	+127.0%	+106.5%
Price	Sep 18, 26	$44.44	-4.9%	-25.5%	-40.0%	-43.8%	-28.0%	+3.5%	+19.4%
200-Day SMA	Sep 18, 26	$72.18	-0.3%	-2.7%	-3.8%	+40.2%	+94.6%	+86.1%	+59.1%
50-Day SMA	Sep 18, 26	$55.97	-0.7%	-13.7%	-25.3%	-27.0%	+18.3%	+37.6%	+47.7%
20-Day SMA	Sep 18, 26	$56.36	-1.3%	+1.4%	-24.5%	-29.4%	+2.6%	+37.5%	+47.3%

10-Day Volatility History

Date	Value	Change
Sep 18, 2026	54.99%	+142.1%
Dec 31, 2025	22.71%	-12.9%
Dec 31, 2024	26.06%	-27.4%
Dec 31, 2023	35.91%	+45.3%
Dec 31, 2022	24.71%	-53.7%
Dec 31, 2021	53.37%	+7.2%
Dec 31, 2020	49.77%	+183.9%
Dec 31, 2019	17.53%	-64.4%
Dec 31, 2018	49.29%	+157.8%
Dec 31, 2017	19.12%	-68.5%
Dec 31, 2016	60.75%	+235.5%
Dec 31, 2015	18.11%	-78.4%
Dec 31, 2014	83.81%	+101.7%
Dec 31, 2013	41.55%	+69.0%
Dec 31, 2012	24.58%	-18.5%
Dec 31, 2011	30.16%	+85.1%
Dec 31, 2010	16.29%	-62.3%
Dec 31, 2009	43.25%	-23.1%

Date	Value	Change
Dec 31, 2008	56.25%	+46.5%
Dec 31, 2007	38.39%	+63.4%
Dec 31, 2006	23.50%	-14.9%
Dec 31, 2005	27.62%	-1.5%
Dec 31, 2004	28.05%	-51.8%
Dec 31, 2003	58.16%	+24.6%
Dec 31, 2002	46.68%	-2.7%
Dec 31, 2001	47.99%	-36.1%
Dec 31, 2000	75.14%	-67.1%
Dec 31, 1999	228.58%	+401.7%
Dec 31, 1998	45.56%	-18.0%
Dec 31, 1997	55.57%	+64.7%
Dec 31, 1996	33.73%	+11.2%
Dec 31, 1995	30.32%	-47.4%
Dec 31, 1994	57.64%	+19.4%
Dec 31, 1993	48.27%	-22.9%
Dec 31, 1992	62.59%	+14.5%
Dec 31, 1991	54.65%	-

FAQ

What is the current 10-day volatility of IONS?: As of today, IONS 10-day volatility is 54.99%
What 10-day volatility category does IONS fall into?: Based on its current 10-day historical volatility, IONS falls into the high volatility category
What is IONS 10-day volatility 1-year high?: IONS 10-day volatility reached a 1-year high of 134.22% on July 10, 2026
What is IONS 10-day volatility 1-year low?: IONS 10-day volatility reached a 1-year low of 10.35% on October 20, 2025

1-Month

51.38%

September 18, 2026

Summary

Current Value: As of today, IONS 1-month volatility is 51.38%, up +1.38% on September 18, 2026
Value Category: Based on its current 1-month historical volatility, IONS falls into the high volatility category
1-Year High: IONS 1-month volatility reached a 1-year high of 127.70% on September 19, 2025
1-Year Low: IONS 1-month volatility reached a 1-year low of 18.28% on October 20, 2025

Performance

IONS Performance
Metric	Date	Value	1D	1M	3M	YTD	1Y	3Y	5Y
1-Month Volatility	Sep 18, 26	51.38%	+1.4%	+41.8%	+134.4%	+130.4%	-57.9%	+95.0%	+59.2%
10-Day Volatility	Sep 18, 26	54.99%	-0.6%	+67.8%	+186.8%	+142.1%	+42.2%	+53.3%	+60.8%
3-Month Volatility	Sep 18, 26	66.12%	+0.8%	+10.0%	+162.6%	+120.5%	-15.6%	+147.1%	+109.4%
1-Year Volatility	Sep 18, 26	41.82%	+0.8%	-21.0%	-10.4%	-20.3%	-21.8%	+23.1%	-3.1%
14-Day RSI	Sep 18, 26	25.37	-10.0%	-52.0%	-47.7%	-50.8%	-65.1%	-59.4%	-44.9%
Beta	Sep 18, 26	0.45	+2.3%	+150.0%	+7.1%	-37.5%	-43.8%	-19.6%	-54.1%
ATR	Sep 18, 26	$2.50	-0.1%	+11.2%	+17.9%	+22.4%	+18.5%	+127.0%	+106.5%
Price	Sep 18, 26	$44.44	-4.9%	-25.5%	-40.0%	-43.8%	-28.0%	+3.5%	+19.4%
200-Day SMA	Sep 18, 26	$72.18	-0.3%	-2.7%	-3.8%	+40.2%	+94.6%	+86.1%	+59.1%
50-Day SMA	Sep 18, 26	$55.97	-0.7%	-13.7%	-25.3%	-27.0%	+18.3%	+37.6%	+47.7%
20-Day SMA	Sep 18, 26	$56.36	-1.3%	+1.4%	-24.5%	-29.4%	+2.6%	+37.5%	+47.3%

1-Month Volatility History

Date	Value	Change
Sep 18, 2026	51.45%	+134.9%
Dec 31, 2025	21.90%	-34.6%
Dec 31, 2024	33.47%	+2.5%
Dec 31, 2023	32.66%	+36.9%
Dec 31, 2022	23.85%	-63.0%
Dec 31, 2021	64.49%	+24.2%
Dec 31, 2020	51.93%	+128.0%
Dec 31, 2019	22.78%	-56.4%
Dec 31, 2018	52.26%	+34.6%
Dec 31, 2017	38.83%	-35.3%
Dec 31, 2016	60.02%	+20.6%
Dec 31, 2015	49.76%	-32.7%
Dec 31, 2014	73.89%	+96.8%
Dec 31, 2013	37.55%	+31.8%
Dec 31, 2012	28.48%	-9.3%
Dec 31, 2011	31.39%	+57.6%
Dec 31, 2010	19.92%	-40.1%
Dec 31, 2009	33.25%	-52.5%

Date	Value	Change
Dec 31, 2008	70.02%	+89.6%
Dec 31, 2007	36.94%	-33.6%
Dec 31, 2006	55.67%	+130.7%
Dec 31, 2005	24.13%	-70.0%
Dec 31, 2004	80.54%	+49.3%
Dec 31, 2003	53.93%	-45.9%
Dec 31, 2002	99.69%	+17.8%
Dec 31, 2001	84.66%	+2.0%
Dec 31, 2000	82.96%	-69.3%
Dec 31, 1999	270.65%	+473.2%
Dec 31, 1998	47.22%	+14.3%
Dec 31, 1997	41.30%	-8.6%
Dec 31, 1996	45.20%	+9.5%
Dec 31, 1995	41.27%	-34.2%
Dec 31, 1994	62.76%	+26.3%
Dec 31, 1993	49.71%	-18.1%
Dec 31, 1992	60.69%	-23.8%
Dec 31, 1991	79.66%	-

FAQ

What is the current 1-month volatility of IONS?: As of today, IONS 1-month volatility is 51.38%
What 1-month volatility category does IONS fall into?: Based on its current 1-month historical volatility, IONS falls into the high volatility category
What is IONS 1-month volatility 1-year high?: IONS 1-month volatility reached a 1-year high of 127.70% on September 19, 2025
What is IONS 1-month volatility 1-year low?: IONS 1-month volatility reached a 1-year low of 18.28% on October 20, 2025

3-Month

66.12%

September 18, 2026

Summary

Current Value: As of today, IONS 3-month volatility is 66.12%, up +0.84% on September 18, 2026
Value Category: Based on its current 3-month historical volatility, IONS falls into the extreme volatility category
1-Year High: IONS 3-month volatility reached a 1-year high of 78.44% on September 19, 2025
1-Year Low: IONS 3-month volatility reached a 1-year low of 24.02% on July 1, 2026

Performance

IONS Performance
Metric	Date	Value	1D	1M	3M	YTD	1Y	3Y	5Y
3-Month Volatility	Sep 18, 26	66.12%	+0.8%	+10.0%	+162.6%	+120.5%	-15.6%	+147.1%	+109.4%
10-Day Volatility	Sep 18, 26	54.99%	-0.6%	+67.8%	+186.8%	+142.1%	+42.2%	+53.3%	+60.8%
1-Month Volatility	Sep 18, 26	51.38%	+1.4%	+41.8%	+134.4%	+130.4%	-57.9%	+95.0%	+59.2%
1-Year Volatility	Sep 18, 26	41.82%	+0.8%	-21.0%	-10.4%	-20.3%	-21.8%	+23.1%	-3.1%
14-Day RSI	Sep 18, 26	25.37	-10.0%	-52.0%	-47.7%	-50.8%	-65.1%	-59.4%	-44.9%
Beta	Sep 18, 26	0.45	+2.3%	+150.0%	+7.1%	-37.5%	-43.8%	-19.6%	-54.1%
ATR	Sep 18, 26	$2.50	-0.1%	+11.2%	+17.9%	+22.4%	+18.5%	+127.0%	+106.5%
Price	Sep 18, 26	$44.44	-4.9%	-25.5%	-40.0%	-43.8%	-28.0%	+3.5%	+19.4%
200-Day SMA	Sep 18, 26	$72.18	-0.3%	-2.7%	-3.8%	+40.2%	+94.6%	+86.1%	+59.1%
50-Day SMA	Sep 18, 26	$55.97	-0.7%	-13.7%	-25.3%	-27.0%	+18.3%	+37.6%	+47.7%
20-Day SMA	Sep 18, 26	$56.36	-1.3%	+1.4%	-24.5%	-29.4%	+2.6%	+37.5%	+47.3%

3-Month Volatility History

Date	Value	Change
Sep 18, 2026	66.12%	+122.3%
Dec 31, 2025	29.75%	-15.4%
Dec 31, 2024	35.17%	-11.3%
Dec 31, 2023	39.65%	+20.3%
Dec 31, 2022	32.96%	-40.4%
Dec 31, 2021	55.32%	+36.6%
Dec 31, 2020	40.50%	+35.6%
Dec 31, 2019	29.87%	-38.9%
Dec 31, 2018	48.92%	-2.0%
Dec 31, 2017	49.94%	-38.4%
Dec 31, 2016	81.03%	+36.2%
Dec 31, 2015	59.49%	+2.0%
Dec 31, 2014	58.33%	+14.8%
Dec 31, 2013	50.83%	-24.5%
Dec 31, 2012	67.34%	+33.7%
Dec 31, 2011	50.36%	+82.1%
Dec 31, 2010	27.65%	-43.7%
Dec 31, 2009	49.13%	-38.2%

Date	Value	Change
Dec 31, 2008	79.49%	+95.3%
Dec 31, 2007	40.71%	-42.5%
Dec 31, 2006	70.81%	+53.5%
Dec 31, 2005	46.12%	-17.8%
Dec 31, 2004	56.08%	+23.4%
Dec 31, 2003	45.44%	-35.1%
Dec 31, 2002	70.01%	+2.3%
Dec 31, 2001	68.41%	-14.3%
Dec 31, 2000	79.85%	-52.8%
Dec 31, 1999	169.34%	+104.6%
Dec 31, 1998	82.78%	+101.3%
Dec 31, 1997	41.13%	-31.1%
Dec 31, 1996	59.73%	+4.9%
Dec 31, 1995	56.94%	-33.5%
Dec 31, 1994	85.67%	+29.4%
Dec 31, 1993	66.18%	-28.1%
Dec 31, 1992	92.02%	+24.5%
Dec 31, 1991	73.93%	-

FAQ

What is the current 3-month volatility of IONS?: As of today, IONS 3-month volatility is 66.12%
What 3-month volatility category does IONS fall into?: Based on its current 3-month historical volatility, IONS falls into the extreme volatility category
What is IONS 3-month volatility 1-year high?: IONS 3-month volatility reached a 1-year high of 78.44% on September 19, 2025
What is IONS 3-month volatility 1-year low?: IONS 3-month volatility reached a 1-year low of 24.02% on July 1, 2026

1-Year

41.82%

September 18, 2026

Summary

Current Value: As of today, IONS 1-year volatility is 41.82%, up +0.84% on September 18, 2026
Value Category: Based on its current 1-year historical volatility, IONS falls into the high volatility category
1-Year High: IONS 1-year volatility reached a 1-year high of 53.73% on November 14, 2025
1-Year Low: IONS 1-year volatility reached a 1-year low of 39.87% on September 9, 2026

Performance

IONS Performance
Metric	Date	Value	1D	1M	3M	YTD	1Y	3Y	5Y
1-Year Volatility	Sep 18, 26	41.82%	+0.8%	-21.0%	-10.4%	-20.3%	-21.8%	+23.1%	-3.1%
10-Day Volatility	Sep 18, 26	54.99%	-0.6%	+67.8%	+186.8%	+142.1%	+42.2%	+53.3%	+60.8%
1-Month Volatility	Sep 18, 26	51.38%	+1.4%	+41.8%	+134.4%	+130.4%	-57.9%	+95.0%	+59.2%
3-Month Volatility	Sep 18, 26	66.12%	+0.8%	+10.0%	+162.6%	+120.5%	-15.6%	+147.1%	+109.4%
1-Year Volatility	Sep 18, 26	41.82%	+0.8%	-21.0%	-10.4%	-20.3%	-21.8%	+23.1%	-3.1%
14-Day RSI	Sep 18, 26	25.37	-10.0%	-52.0%	-47.7%	-50.8%	-65.1%	-59.4%	-44.9%
Beta	Sep 18, 26	0.45	+2.3%	+150.0%	+7.1%	-37.5%	-43.8%	-19.6%	-54.1%
ATR	Sep 18, 26	$2.50	-0.1%	+11.2%	+17.9%	+22.4%	+18.5%	+127.0%	+106.5%
Price	Sep 18, 26	$44.44	-4.9%	-25.5%	-40.0%	-43.8%	-28.0%	+3.5%	+19.4%
200-Day SMA	Sep 18, 26	$72.18	-0.3%	-2.7%	-3.8%	+40.2%	+94.6%	+86.1%	+59.1%
50-Day SMA	Sep 18, 26	$55.97	-0.7%	-13.7%	-25.3%	-27.0%	+18.3%	+37.6%	+47.7%
20-Day SMA	Sep 18, 26	$56.36	-1.3%	+1.4%	-24.5%	-29.4%	+2.6%	+37.5%	+47.3%

1-Year Volatility History

Date	Value	Change
Sep 18, 2026	41.75%	-20.4%
Dec 31, 2025	52.46%	+44.0%
Dec 31, 2024	36.42%	+1.3%
Dec 31, 2023	35.95%	-21.4%
Dec 31, 2022	45.74%	-2.9%
Dec 31, 2021	47.09%	+8.5%
Dec 31, 2020	43.41%	+13.9%
Dec 31, 2019	38.12%	-21.0%
Dec 31, 2018	48.23%	-1.0%
Dec 31, 2017	48.72%	-42.0%
Dec 31, 2016	84.01%	+60.8%
Dec 31, 2015	52.24%	-17.0%
Dec 31, 2014	62.92%	+2.5%
Dec 31, 2013	61.39%	+17.5%
Dec 31, 2012	52.26%	+25.8%
Dec 31, 2011	41.54%	-2.9%
Dec 31, 2010	42.80%	-8.1%
Dec 31, 2009	46.59%	-33.8%

Date	Value	Change
Dec 31, 2008	70.42%	+53.2%
Dec 31, 2007	45.96%	-19.4%
Dec 31, 2006	57.00%	+9.5%
Dec 31, 2005	52.05%	-15.4%
Dec 31, 2004	61.50%	-7.4%
Dec 31, 2003	66.43%	-14.1%
Dec 31, 2002	77.34%	-9.1%
Dec 31, 2001	85.04%	-24.9%
Dec 31, 2000	113.29%	+17.9%
Dec 31, 1999	96.12%	+37.1%
Dec 31, 1998	70.13%	+62.1%
Dec 31, 1997	43.27%	-39.9%
Dec 31, 1996	71.98%	-0.5%
Dec 31, 1995	72.31%	+6.3%
Dec 31, 1994	68.02%	+24.9%
Dec 31, 1993	54.46%	-24.9%
Dec 31, 1992	72.49%	-4.4%
Dec 31, 1991	75.86%	-

FAQ

What is the current 1-year volatility of IONS?: As of today, IONS 1-year volatility is 41.82%
What 1-year volatility category does IONS fall into?: Based on its current 1-year historical volatility, IONS falls into the high volatility category
What is IONS 1-year volatility 1-year high?: IONS 1-year volatility reached a 1-year high of 53.73% on November 14, 2025
What is IONS 1-year volatility 1-year low?: IONS 1-year volatility reached a 1-year low of 39.87% on September 9, 2026

Data Sources & References

IONS Official Website www.ionis.com
Most Recent Annual Report (10-K) www.sec.gov/Archives/edgar/data/874015/000087401526000115/0000874015-26-000115-index.htm
IONS Profile on Yahoo Finance finance.yahoo.com/quote/IONS
IONS Profile on NASDAQ.com www.nasdaq.com/market-activity/stocks/ions