Ionis Pharmaceuticals, Inc. company logo
Ionis Pharmaceuticals, Inc. logo

Ionis Pharmaceuticals, Inc. (IONS) EV/EBITDA

EV/EBITDA

-49.411.38+2.72%

Summary

Current Value
As of today, IONS EV/EBITDA is -49.41, up +2.72% on
All-time High
IONS EV/EBITDA is currently -113.80% below its historical high of 358.10 set on
1-Year High
IONS EV/EBITDA reached a 1-year high of -10.87 on
1-Year Low
IONS EV/EBITDA reached a 1-year low of -51.74 on
1-Year Change
IONS EV/EBITDA is down -236.35% year-over-year
Sector rank
IONS EV/EBITDA is higher than 2.46% of companies in Healthcare sector

Chart

Add series to chart
Add series to chart1/6
Series
SUGGESTED SERIES

Performance

IONS Performance
MetricDateValue1D1M3MYTD1Y3Y5Y
EV/EBITDA-49.41+2.7%+1.7%-13.4%-0.5%-236.3%-123.6%+25.4%
Price$79.48-2.7%-1.7%+12.6%+0.5%+127.5%+99.5%+33.2%
PE Ratio-
TTM Revenue$967.38M+2.4%+2.4%+20.4%+10.5%+3.7%
TTM EPS-$1.71+7.6%+7.6%+29.9%-1233.8%-406.7%
Enterprise Value$12.68B-2.7%-1.7%+13.4%+0.5%+145.1%+151.9%+71.0%
TTM EBITDA-$256.61M-5.1%-5.1%+26.3%-759.9%-300.6%
Market Cap$13B-2.7%-1.7%+13.2%+0.5%+133.3%+127.4%+53.8%

Highs

IONS EV/EBITDA Highs Comparison
PeriodHighDateCurrent
1M-47.90-3.1%
3M-43.14-14.5%
6M-25.73-92.0%
1Y-10.87-354.6%
3Y-10.87-354.6%
5Y268.94-118.4%
All358.10-113.8%

Lows

IONS EV/EBITDA Lows Comparison
PeriodLowDateCurrent
1M-51.74+4.5%
3M-51.74+4.5%
6M-51.74+4.5%
1Y-51.74+4.5%
3Y-51.74+4.5%
5Y-2,185.18+97.7%
All-3,014.77+98.4%

History

DateValueChange
-49.41-0.5%
-49.18-234.6%
-14.70+50.3%
-29.56-42.1%
-20.80+96.7%
-634.72-918.0%
-62.35-438.9%
18.40+105.8%
-319.46-297.7%
161.56+127.1%
-595.49-241.9%
-174.19+43.0%
-305.56-174.6%
-111.27-576.8%
-16.44-58.1%
DateValueChange
-10.40-59.0%
-6.54+9.5%
-7.23+24.9%
-9.63+63.0%
-26.06-56.8%
-16.62-182.7%
-5.88+52.5%
-12.38-11.7%
-11.08+30.0%
-15.83-38.1%
-11.46-275.7%
-3.05+47.1%
-5.77+8.8%
-6.33+60.4%
-15.98-

FAQ

  • What is the current EV/EBITDA of IONS?

    As of today, IONS EV/EBITDA is -49.41

  • What is IONS EV/EBITDA 1-year high?

    IONS EV/EBITDA reached a 1-year high of -10.87 on April 8, 2025

  • What is IONS EV/EBITDA 1-year low?

    IONS EV/EBITDA reached a 1-year low of -51.74 on January 7, 2026

  • What is 1-year change in IONS EV/EBITDA?

    IONS EV/EBITDA is down -236.35% year-over-year

  • What is 3-year change in IONS EV/EBITDA?

    IONS EV/EBITDA is down -123.57% over the past 3 years

  • How far is IONS EV/EBITDA from its all-time high?

    IONS EV/EBITDA is currently -113.80% below its historical high of 358.10 set on April 23, 2018

  • How does IONS EV/EBITDA rank versus sector peers?

    IONS EV/EBITDA is higher than 2.46% of companies in Healthcare sector

EV/EBITDA Formula

EV/EBITDA =  

EBITDA

Data Sources & References

  1. IONS Official Website www.ionis.com
  2. Most Recent Annual Report (10-K) www.sec.gov/Archives/edgar/data/874015/000087401525000089/0000874015-25-000089-index.htm
  3. IONS Profile on Yahoo Finance finance.yahoo.com/quote/IONS
  4. IONS Profile on NASDAQ.com www.nasdaq.com/market-activity/stocks/ions