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Ionis Pharmaceuticals, Inc. (IONS) Cash from operations

annual CFO:

-$500.95M-$193.43M(-62.90%)
December 31, 2024

Summary

  • As of today (August 20, 2025), IONS annual cash flow from operations is -$500.95 million, with the most recent change of -$193.43 million (-62.90%) on December 31, 2024.
  • During the last 3 years, IONS annual CFO has fallen by -$531.75 million (-1726.50%).
  • IONS annual CFO is now -183.09% below its all-time high of $602.89 million, reached on December 31, 2018.

Performance

IONS Cash from operations Chart

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quarterly CFO:

$151.34M+$302.11M(+200.37%)
June 30, 2025

Summary

  • As of today (August 20, 2025), IONS quarterly cash flow from operations is $151.34 million, with the most recent change of +$302.11 million (+200.37%) on June 30, 2025.
  • Over the past year, IONS quarterly CFO has increased by +$271.22 million (+226.24%).
  • IONS quarterly CFO is now -69.75% below its all-time high of $500.24 million, reached on June 30, 2018.

Performance

IONS quarterly CFO Chart

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TTM CFO:

-$230.57M+$271.22M(+54.05%)
June 30, 2025

Summary

  • As of today (August 20, 2025), IONS TTM cash flow from operations is -$230.57 million, with the most recent change of +$271.22 million (+54.05%) on June 30, 2025.
  • Over the past year, IONS TTM CFO has increased by +$115.41 million (+33.36%).
  • IONS TTM CFO is now -133.06% below its all-time high of $697.43 million, reached on March 31, 2019.

Performance

IONS TTM CFO Chart

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Cash from operations Formula

CFO = Net Income + Non Cash Expenses + Changes In Working Capital

IONS Cash from operations Trends

PeriodPeriodAnnualAnnualQuarterlyQuarterlyTTMTTM
1 y1 year-62.9%+226.2%+33.4%
3 y3 years-1726.5%+936.3%-334.4%
5 y5 years-244.9%+442.3%-208.1%

IONS Cash from operations Highs & Lows

PeriodPeriodAnnual vs highAnnual vs highAnnual vs lowAnnual vs lowQuarter. vs highQuarter. vs highQuarter. vs lowQuarter. vs lowTTM vs highTTM vs highTTM vs lowTTM vs low
3 y3-year-1726.5%at lowat high+175.6%-278.0%+57.4%
5 y5-year-244.9%at low-25.7%+175.6%-206.8%+57.4%
alltimeall time-183.1%at low-69.8%+175.6%-133.1%+57.4%

IONS Cash from operations History

DateAnnualQuarterlyTTM
Jun 2025
-
$151.34M(-200.4%)
-$230.57M(-54.1%)
Mar 2025
-
-$150.78M(+29.8%)
-$501.78M(+0.2%)
Dec 2024
-$500.95M(+62.9%)
-$116.14M(+1.0%)
-$500.95M(+42.3%)
Sep 2024
-
-$114.99M(-4.1%)
-$351.94M(+1.7%)
Jun 2024
-
-$119.88M(-20.0%)
-$345.98M(+7.0%)
Mar 2024
-
-$149.94M(-556.2%)
-$323.46M(+5.2%)
Dec 2023
-$307.51M(+12.1%)
$32.87M(-130.1%)
-$307.51M(-43.1%)
Sep 2023
-
-$109.02M(+12.0%)
-$540.57M(+18.6%)
Jun 2023
-
-$97.36M(-27.3%)
-$455.98M(+21.0%)
Mar 2023
-
-$133.99M(-33.1%)
-$376.71M(+37.3%)
Dec 2022
-$274.37M(-990.8%)
-$200.19M(+719.5%)
-$274.37M(-311.8%)
Sep 2022
-
-$24.43M(+35.0%)
$129.51M(+31.7%)
Jun 2022
-
-$18.10M(-42.8%)
$98.37M(+82.8%)
Mar 2022
-
-$31.65M(-115.5%)
$53.81M(+74.7%)
Dec 2021
$30.80M(-14.2%)
$203.69M(-466.5%)
$30.80M(-141.1%)
Sep 2021
-
-$55.57M(-11.3%)
-$74.91M(+153.0%)
Jun 2021
-
-$62.65M(+14.6%)
-$29.61M(+164.9%)
Mar 2021
-
-$54.66M(-155.8%)
-$11.18M(-131.1%)
Dec 2020
$35.89M(-89.6%)
$97.98M(-1053.5%)
$35.89M(-83.4%)
Sep 2020
-
-$10.28M(-76.8%)
$215.85M(+1.2%)
Jun 2020
-
-$44.22M(+482.4%)
$213.32M(-7.4%)
Mar 2020
-
-$7.59M(-102.7%)
$230.42M(-33.3%)
Dec 2019
$345.72M(-42.7%)
$277.93M(-2270.3%)
$345.72M(+88.6%)
Sep 2019
-
-$12.81M(-52.8%)
$183.28M(+7.8%)
Jun 2019
-
-$27.11M(-125.2%)
$170.08M(-75.6%)
Mar 2019
-
$107.70M(-6.7%)
$697.43M(+15.7%)
Dec 2018
$602.89M(+246.2%)
$115.49M(-544.1%)
$602.89M(+18.7%)
Sep 2018
-
-$26.00M(-105.2%)
$507.80M(-9.7%)
Jun 2018
-
$500.24M(+3699.7%)
$562.52M(+770.1%)
Mar 2018
-
$13.16M(-35.5%)
$64.65M(-62.9%)
Dec 2017
$174.15M(-255.3%)
$20.40M(-29.0%)
$174.15M(+36.3%)
Sep 2017
-
$28.72M(+1115.4%)
$127.79M(+4.3%)
Jun 2017
-
$2.36M(-98.1%)
$122.47M(+41.9%)
Mar 2017
-
$122.67M(-572.5%)
$86.33M(-177.0%)
Dec 2016
-$112.11M(-630.7%)
-$25.96M(-210.9%)
-$112.11M(-9.3%)
Sep 2016
-
$23.41M(-169.3%)
-$123.62M(+11.6%)
Jun 2016
-
-$33.78M(-55.4%)
-$110.81M(+837.7%)
Mar 2016
-
-$75.77M(+102.2%)
-$11.82M(-155.9%)
Dec 2015
$21.13M(+236.1%)
-$37.47M(-203.5%)
$21.13M(-83.7%)
Sep 2015
-
$36.22M(-44.5%)
$129.28M(+36.1%)
Jun 2015
-
$65.21M(-252.3%)
$95.01M(-2355.1%)
Mar 2015
-
-$42.83M(-160.6%)
-$4.21M(-167.0%)
Dec 2014
$6.29M(-90.1%)
$70.68M(+3536.0%)
$6.29M(-108.0%)
Sep 2014
-
$1.94M(-105.7%)
-$78.89M(+425.4%)
Jun 2014
-
-$34.02M(+5.2%)
-$15.01M(-136.0%)
Mar 2014
-
-$32.33M(+123.1%)
$41.74M(-34.3%)
Dec 2013
$63.49M(+3284.5%)
-$14.49M(-122.0%)
$63.49M(-44.3%)
Sep 2013
-
$65.82M(+189.5%)
$114.02M(+388.8%)
Jun 2013
-
$22.74M(-315.0%)
$23.33M(-1272.9%)
Mar 2013
-
-$10.58M(-129.3%)
-$1.99M(-206.0%)
Dec 2012
$1.88M(-101.6%)
$36.03M(-244.9%)
$1.88M(-103.2%)
Sep 2012
-
-$24.87M(+865.1%)
-$58.49M(+0.7%)
Jun 2012
-
-$2.58M(-61.6%)
-$58.07M(-28.9%)
Mar 2012
-
-$6.71M(-72.4%)
-$81.67M(-28.9%)
Dec 2011
-$114.80M(+80.5%)
-$24.33M(-0.5%)
-$114.80M(-1.0%)
Sep 2011
-
-$24.45M(-6.6%)
-$115.97M(+2.7%)
Jun 2011
-
-$26.18M(-34.3%)
-$112.95M(+38.2%)
Mar 2011
-
-$39.84M(+56.2%)
-$81.74M(+28.5%)
Dec 2010
-$63.59M(-41.4%)
-$25.50M(+19.0%)
-$63.59M(-8.7%)
Sep 2010
-
-$21.43M(-526.0%)
-$69.62M(-13.4%)
Jun 2010
-
$5.03M(-123.2%)
-$80.39M(-16.1%)
Mar 2010
-
-$21.69M(-31.2%)
-$95.79M(-11.7%)
Dec 2009
-$108.44M(-151.1%)
-$31.53M(-2.1%)
-$108.44M(+12.9%)
Sep 2009
-
-$32.19M(+210.4%)
-$96.08M(+12.5%)
Jun 2009
-
-$10.37M(-69.8%)
-$85.44M(-183.3%)
Mar 2009
-
-$34.35M(+79.1%)
$102.57M(-51.6%)
Dec 2008
$212.03M
-$19.18M(-11.0%)
$212.03M(-23.5%)
Sep 2008
-
-$21.55M(-112.1%)
$277.06M(-10.9%)
Jun 2008
-
$177.64M(+136.5%)
$311.02M(+135.6%)
DateAnnualQuarterlyTTM
Mar 2008
-
$75.11M(+63.8%)
$132.00M(+265.7%)
Dec 2007
$36.09M(-167.8%)
$45.86M(+269.7%)
$36.09M(-293.7%)
Sep 2007
-
$12.40M(-1004.7%)
-$18.63M(-58.6%)
Jun 2007
-
-$1.37M(-93.4%)
-$44.99M(-22.4%)
Mar 2007
-
-$20.80M(+134.4%)
-$57.96M(+8.9%)
Dec 2006
-$53.23M(-13.8%)
-$8.87M(-36.4%)
-$53.23M(-9.4%)
Sep 2006
-
-$13.96M(-2.6%)
-$58.72M(+15.7%)
Jun 2006
-
-$14.33M(-10.8%)
-$50.74M(-9.0%)
Mar 2006
-
-$16.06M(+11.8%)
-$55.77M(-9.7%)
Dec 2005
-$61.74M(-39.3%)
-$14.37M(+140.2%)
-$61.74M(-14.4%)
Sep 2005
-
-$5.98M(-69.1%)
-$72.15M(-18.3%)
Jun 2005
-
-$19.36M(-12.1%)
-$88.26M(-12.0%)
Mar 2005
-
-$22.03M(-11.1%)
-$100.32M(-1.4%)
Dec 2004
-$101.75M(+6.6%)
-$24.78M(+12.2%)
-$101.75M(-7.0%)
Sep 2004
-
-$22.09M(-29.7%)
-$109.38M(-0.6%)
Jun 2004
-
-$31.42M(+33.9%)
-$110.05M(+9.0%)
Mar 2004
-
-$23.47M(-27.6%)
-$100.94M(+5.7%)
Dec 2003
-$95.47M(+1.2%)
-$32.41M(+42.4%)
-$95.47M(+30.6%)
Sep 2003
-
-$22.76M(+2.0%)
-$73.08M(+14.3%)
Jun 2003
-
-$22.30M(+23.9%)
-$63.91M(-33.9%)
Mar 2003
-
-$18.00M(+79.7%)
-$96.66M(+2.4%)
Dec 2002
-$94.38M(+1432.7%)
-$10.02M(-26.3%)
-$94.38M(-1.0%)
Sep 2002
-
-$13.59M(-75.3%)
-$95.30M(+80.8%)
Jun 2002
-
-$55.05M(+249.9%)
-$52.71M(+992.3%)
Mar 2002
-
-$15.73M(+43.9%)
-$4.83M(-21.6%)
Dec 2001
-$6.16M(-73.4%)
-$10.93M(-137.7%)
-$6.16M(+438.3%)
Sep 2001
-
$29.00M(-505.0%)
-$1.14M(-95.9%)
Jun 2001
-
-$7.16M(-58.0%)
-$28.02M(-4.0%)
Mar 2001
-
-$17.06M(+188.3%)
-$29.20M(+25.9%)
Dec 2000
-$23.19M(-52.1%)
-$5.92M(-379.5%)
-$23.19M(-17.8%)
Sep 2000
-
$2.12M(-125.4%)
-$28.21M(-28.4%)
Jun 2000
-
-$8.33M(-24.6%)
-$39.40M(-13.2%)
Mar 2000
-
-$11.05M(+1.0%)
-$45.38M(-6.2%)
Dec 1999
-$48.36M(+39.3%)
-$10.94M(+20.6%)
-$48.36M(+1.8%)
Sep 1999
-
-$9.07M(-36.6%)
-$47.49M(-1.0%)
Jun 1999
-
-$14.31M(+1.9%)
-$47.96M(+51.9%)
Mar 1999
-
-$14.04M(+39.4%)
-$31.58M(-9.0%)
Dec 1998
-$34.72M(+68.9%)
-$10.07M(+5.6%)
-$34.72M(+12.5%)
Sep 1998
-
-$9.54M(-560.7%)
-$30.85M(+28.5%)
Jun 1998
-
$2.07M(-112.0%)
-$24.01M(-29.5%)
Mar 1998
-
-$17.18M(+177.1%)
-$34.08M(+65.4%)
Dec 1997
-$20.55M(-2.8%)
-$6.20M(+129.6%)
-$20.60M(+0.5%)
Sep 1997
-
-$2.70M(-66.3%)
-$20.50M(-13.5%)
Jun 1997
-
-$8.00M(+116.2%)
-$23.70M(+0.9%)
Mar 1997
-
-$3.70M(-39.3%)
-$23.50M(+10.8%)
Dec 1996
-$21.15M(+40.3%)
-$6.10M(+3.4%)
-$21.20M(-3.6%)
Sep 1996
-
-$5.90M(-24.4%)
-$22.00M(+43.8%)
Jun 1996
-
-$7.80M(+457.1%)
-$15.30M(+39.1%)
Mar 1996
-
-$1.40M(-79.7%)
-$11.00M(-27.2%)
Dec 1995
-$15.08M(-1.0%)
-$6.90M(-962.5%)
-$15.10M(+34.8%)
Sep 1995
-
$800.00K(-122.9%)
-$11.20M(-20.0%)
Jun 1995
-
-$3.50M(-36.4%)
-$14.00M(+0.7%)
Mar 1995
-
-$5.50M(+83.3%)
-$13.90M(-8.6%)
Dec 1994
-$15.23M(-0.5%)
-$3.00M(+50.0%)
-$15.20M(+7.0%)
Sep 1994
-
-$2.00M(-41.2%)
-$14.20M(-2.1%)
Jun 1994
-
-$3.40M(-50.0%)
-$14.50M(-15.7%)
Mar 1994
-
-$6.80M(+240.0%)
-$17.20M(+12.4%)
Dec 1993
-$15.30M(-21.0%)
-$2.00M(-13.0%)
-$15.30M(-13.6%)
Sep 1993
-
-$2.30M(-62.3%)
-$17.70M(-7.3%)
Jun 1993
-
-$6.10M(+24.5%)
-$19.10M(+9.8%)
Mar 1993
-
-$4.90M(+11.4%)
-$17.40M(-10.3%)
Dec 1992
-$19.37M(+1201.1%)
-$4.40M(+18.9%)
-$19.40M(+23.6%)
Sep 1992
-
-$3.70M(-15.9%)
-$15.70M(+4.7%)
Jun 1992
-
-$4.40M(-36.2%)
-$15.00M(+38.9%)
Mar 1992
-
-$6.90M(+885.7%)
-$10.80M(+620.0%)
Dec 1991
-$1.49M
-$700.00K(-76.7%)
-$1.50M(+87.5%)
Sep 1991
-
-$3.00M(+1400.0%)
-$800.00K(-136.4%)
Jun 1991
-
-$200.00K(-108.3%)
$2.20M(-8.3%)
Mar 1991
-
$2.40M
$2.40M

FAQ

  • What is Ionis Pharmaceuticals, Inc. annual cash flow from operations?
  • What is the all time high annual CFO for Ionis Pharmaceuticals, Inc.?
  • What is Ionis Pharmaceuticals, Inc. annual CFO year-on-year change?
  • What is Ionis Pharmaceuticals, Inc. quarterly cash flow from operations?
  • What is the all time high quarterly CFO for Ionis Pharmaceuticals, Inc.?
  • What is Ionis Pharmaceuticals, Inc. quarterly CFO year-on-year change?
  • What is Ionis Pharmaceuticals, Inc. TTM cash flow from operations?
  • What is the all time high TTM CFO for Ionis Pharmaceuticals, Inc.?
  • What is Ionis Pharmaceuticals, Inc. TTM CFO year-on-year change?

What is Ionis Pharmaceuticals, Inc. annual cash flow from operations?

The current annual CFO of IONS is -$500.95M

What is the all time high annual CFO for Ionis Pharmaceuticals, Inc.?

Ionis Pharmaceuticals, Inc. all-time high annual cash flow from operations is $602.89M

What is Ionis Pharmaceuticals, Inc. annual CFO year-on-year change?

Over the past year, IONS annual cash flow from operations has changed by -$193.43M (-62.90%)

What is Ionis Pharmaceuticals, Inc. quarterly cash flow from operations?

The current quarterly CFO of IONS is $151.34M

What is the all time high quarterly CFO for Ionis Pharmaceuticals, Inc.?

Ionis Pharmaceuticals, Inc. all-time high quarterly cash flow from operations is $500.24M

What is Ionis Pharmaceuticals, Inc. quarterly CFO year-on-year change?

Over the past year, IONS quarterly cash flow from operations has changed by +$271.22M (+226.24%)

What is Ionis Pharmaceuticals, Inc. TTM cash flow from operations?

The current TTM CFO of IONS is -$230.57M

What is the all time high TTM CFO for Ionis Pharmaceuticals, Inc.?

Ionis Pharmaceuticals, Inc. all-time high TTM cash flow from operations is $697.43M

What is Ionis Pharmaceuticals, Inc. TTM CFO year-on-year change?

Over the past year, IONS TTM cash flow from operations has changed by +$115.41M (+33.36%)
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