Annual CFO:
-$500.95M-$193.43M(-62.90%)Summary
- As of today, IONS annual cash from operations is -$500.95 million, with the most recent change of -$193.43 million (-62.90%) on December 31, 2024.
- During the last 3 years, IONS annual cash from operations has fallen by -$531.75 million (-1726.50%).
- IONS annual cash from operations is now -183.09% below its all-time high of $602.89 million, reached on December 31, 2018.
Performance
IONS Cash From Operations Chart
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Range
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Quarterly CFO:
-$131.44M-$282.77M(-186.85%)Summary
- As of today, IONS quarterly cash from operations is -$131.44 million, with the most recent change of -$282.77 million (-186.85%) on September 1, 2025.
- Over the past year, IONS quarterly cash from operations has dropped by -$16.45 million (-14.30%).
- IONS quarterly cash from operations is now -126.27% below its all-time high of $500.24 million, reached on June 30, 2018.
Performance
IONS Quarterly Cash From Operations Chart
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TTM CFO:
-$247.01M-$16.45M(-7.13%)Summary
- As of today, IONS TTM cash from operations is -$247.01 million, with the most recent change of -$16.45 million (-7.13%) on September 1, 2025.
- Over the past year, IONS TTM cash from operations has increased by +$104.93 million (+29.81%).
- IONS TTM cash from operations is now -135.42% below its all-time high of $697.43 million, reached on March 31, 2019.
Performance
IONS TTM Cash From Operations Chart
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Cash From Operations Formula
CFO = Net Income + Non Cash Expenses + Changes In Working Capital
IONS Cash From Operations Trends
| PeriodPeriod | AnnualAnnual | QuarterlyQuarterly | TTMTTM |
|---|---|---|---|
| 1Y1 Year | -62.9% | -14.3% | +29.8% |
| 3Y3 Years | -1726.5% | -438.0% | -290.7% |
| 5Y5 Years | -244.9% | -1179.2% | -214.4% |
IONS Cash From Operations Highs & Lows
| PeriodPeriod | Annual vs HighAnnual vs High | Annual vs LowAnnual vs Low | Quarter. vs HighQuarter. vs High | Quarter. vs LowQuarter. vs Low | TTM vs HighTTM vs High | TTM vs LowTTM vs Low | |
|---|---|---|---|---|---|---|---|
| 3Y | 3-Year | -1726.5% | at low | -186.8% | +34.4% | -290.7% | +54.3% |
| 5Y | 5-Year | -244.9% | at low | -164.5% | +34.4% | -214.4% | +54.3% |
| All-Time | All-Time | -183.1% | at low | -126.3% | +34.4% | -135.4% | +54.3% |
IONS Cash From Operations History
| Date | Annual | Quarterly | TTM |
|---|---|---|---|
| Sep 2025 | - | -$131.44M(-186.8%) | -$247.01M(-7.1%) |
| Jun 2025 | - | $151.34M(+200.4%) | -$230.57M(+54.1%) |
| Mar 2025 | - | -$150.78M(-29.8%) | -$501.78M(-0.2%) |
| Dec 2024 | -$500.95M(-62.9%) | -$116.14M(-1.0%) | -$500.95M(-42.3%) |
| Sep 2024 | - | -$114.99M(+4.1%) | -$351.94M(-1.7%) |
| Jun 2024 | - | -$119.88M(+20.0%) | -$345.98M(-7.0%) |
| Mar 2024 | - | -$149.94M(-556.2%) | -$323.46M(-5.2%) |
| Dec 2023 | -$307.51M(-12.1%) | $32.87M(+130.1%) | -$307.51M(+43.1%) |
| Sep 2023 | - | -$109.02M(-12.0%) | -$540.57M(-18.6%) |
| Jun 2023 | - | -$97.36M(+27.3%) | -$455.98M(-21.0%) |
| Mar 2023 | - | -$133.99M(+33.1%) | -$376.71M(-37.3%) |
| Dec 2022 | -$274.37M(-990.8%) | -$200.19M(-719.5%) | -$274.37M(-311.8%) |
| Sep 2022 | - | -$24.43M(-35.0%) | $129.51M(+31.7%) |
| Jun 2022 | - | -$18.10M(+42.8%) | $98.37M(+82.8%) |
| Mar 2022 | - | -$31.65M(-115.5%) | $53.81M(+74.7%) |
| Dec 2021 | $30.80M(-14.2%) | $203.69M(+466.5%) | $30.80M(+141.1%) |
| Sep 2021 | - | -$55.57M(+11.3%) | -$74.91M(-153.0%) |
| Jun 2021 | - | -$62.65M(-14.6%) | -$29.61M(-164.9%) |
| Mar 2021 | - | -$54.66M(-155.8%) | -$11.18M(-131.1%) |
| Dec 2020 | $35.89M(-89.6%) | $97.98M(+1053.5%) | $35.89M(-83.4%) |
| Sep 2020 | - | -$10.28M(+76.8%) | $215.85M(+1.2%) |
| Jun 2020 | - | -$44.22M(-482.4%) | $213.32M(-7.4%) |
| Mar 2020 | - | -$7.59M(-102.7%) | $230.42M(-33.3%) |
| Dec 2019 | $345.72M(-42.7%) | $277.93M(+2270.3%) | $345.72M(+88.6%) |
| Sep 2019 | - | -$12.81M(+52.8%) | $183.28M(+7.8%) |
| Jun 2019 | - | -$27.11M(-125.2%) | $170.08M(-75.6%) |
| Mar 2019 | - | $107.70M(-6.7%) | $697.43M(+15.7%) |
| Dec 2018 | $602.89M(+246.2%) | $115.49M(+544.1%) | $602.89M(+18.7%) |
| Sep 2018 | - | -$26.00M(-105.2%) | $507.80M(-9.7%) |
| Jun 2018 | - | $500.24M(+3699.7%) | $562.52M(+770.1%) |
| Mar 2018 | - | $13.16M(-35.5%) | $64.65M(-62.9%) |
| Dec 2017 | $174.15M(+255.3%) | $20.40M(-29.0%) | $174.15M(+36.3%) |
| Sep 2017 | - | $28.72M(+1115.4%) | $127.79M(+4.3%) |
| Jun 2017 | - | $2.36M(-98.1%) | $122.47M(+41.9%) |
| Mar 2017 | - | $122.67M(+572.5%) | $86.33M(+177.0%) |
| Dec 2016 | -$112.11M(-630.7%) | -$25.96M(-210.9%) | -$112.11M(+9.3%) |
| Sep 2016 | - | $23.41M(+169.3%) | -$123.62M(-11.6%) |
| Jun 2016 | - | -$33.78M(+55.4%) | -$110.81M(-837.7%) |
| Mar 2016 | - | -$75.77M(-102.2%) | -$11.82M(-155.9%) |
| Dec 2015 | $21.13M(+236.1%) | -$37.47M(-203.5%) | $21.13M(-83.7%) |
| Sep 2015 | - | $36.22M(-44.5%) | $129.28M(+36.1%) |
| Jun 2015 | - | $65.21M(+252.3%) | $95.01M(+2355.1%) |
| Mar 2015 | - | -$42.83M(-160.6%) | -$4.21M(-167.0%) |
| Dec 2014 | $6.29M(-90.1%) | $70.68M(+3536.0%) | $6.29M(+108.0%) |
| Sep 2014 | - | $1.94M(+105.7%) | -$78.89M(-425.4%) |
| Jun 2014 | - | -$34.02M(-5.2%) | -$15.01M(-136.0%) |
| Mar 2014 | - | -$32.33M(-123.1%) | $41.74M(-34.3%) |
| Dec 2013 | $63.49M(+3284.5%) | -$14.49M(-122.0%) | $63.49M(-44.3%) |
| Sep 2013 | - | $65.82M(+189.5%) | $114.02M(+388.8%) |
| Jun 2013 | - | $22.74M(+315.0%) | $23.33M(+1272.9%) |
| Mar 2013 | - | -$10.58M(-129.3%) | -$1.99M(-206.0%) |
| Dec 2012 | $1.88M(+101.6%) | $36.03M(+244.9%) | $1.88M(+103.2%) |
| Sep 2012 | - | -$24.87M(-865.1%) | -$58.49M(-0.7%) |
| Jun 2012 | - | -$2.58M(+61.6%) | -$58.07M(+28.9%) |
| Mar 2012 | - | -$6.71M(+72.4%) | -$81.67M(+28.9%) |
| Dec 2011 | -$114.80M(-80.5%) | -$24.33M(+0.5%) | -$114.80M(+1.0%) |
| Sep 2011 | - | -$24.45M(+6.6%) | -$115.97M(-2.7%) |
| Jun 2011 | - | -$26.18M(+34.3%) | -$112.95M(-38.2%) |
| Mar 2011 | - | -$39.84M(-56.2%) | -$81.74M(-28.5%) |
| Dec 2010 | -$63.59M(+41.4%) | -$25.50M(-19.0%) | -$63.59M(+8.7%) |
| Sep 2010 | - | -$21.43M(-526.0%) | -$69.62M(+13.4%) |
| Jun 2010 | - | $5.03M(+123.2%) | -$80.39M(+16.1%) |
| Mar 2010 | - | -$21.69M(+31.2%) | -$95.79M(+11.7%) |
| Dec 2009 | -$108.44M(-151.1%) | -$31.53M(+2.1%) | -$108.44M(-12.9%) |
| Sep 2009 | - | -$32.19M(-210.4%) | -$96.08M(-12.5%) |
| Jun 2009 | - | -$10.37M(+69.8%) | -$85.44M(-183.3%) |
| Mar 2009 | - | -$34.35M(-79.1%) | $102.57M(-51.6%) |
| Dec 2008 | $212.03M | -$19.18M(+11.0%) | $212.03M(-23.5%) |
| Sep 2008 | - | -$21.55M(-112.1%) | $277.06M(-10.9%) |
| Date | Annual | Quarterly | TTM |
|---|---|---|---|
| Jun 2008 | - | $177.64M(+136.5%) | $311.02M(+135.6%) |
| Mar 2008 | - | $75.11M(+63.8%) | $132.00M(+265.7%) |
| Dec 2007 | $36.09M(+167.8%) | $45.86M(+269.7%) | $36.09M(+293.7%) |
| Sep 2007 | - | $12.40M(+1004.7%) | -$18.63M(+58.6%) |
| Jun 2007 | - | -$1.37M(+93.4%) | -$44.99M(+22.4%) |
| Mar 2007 | - | -$20.80M(-134.4%) | -$57.96M(-8.9%) |
| Dec 2006 | -$53.23M(+13.8%) | -$8.87M(+36.4%) | -$53.23M(+9.4%) |
| Sep 2006 | - | -$13.96M(+2.6%) | -$58.72M(-15.7%) |
| Jun 2006 | - | -$14.33M(+10.8%) | -$50.74M(+9.0%) |
| Mar 2006 | - | -$16.06M(-11.8%) | -$55.77M(+9.7%) |
| Dec 2005 | -$61.74M(+39.3%) | -$14.37M(-140.2%) | -$61.74M(+14.4%) |
| Sep 2005 | - | -$5.98M(+69.1%) | -$72.15M(+18.3%) |
| Jun 2005 | - | -$19.36M(+12.1%) | -$88.26M(+12.0%) |
| Mar 2005 | - | -$22.03M(+11.1%) | -$100.32M(+1.4%) |
| Dec 2004 | -$101.75M(-6.6%) | -$24.78M(-12.2%) | -$101.75M(+7.0%) |
| Sep 2004 | - | -$22.09M(+29.7%) | -$109.38M(+0.6%) |
| Jun 2004 | - | -$31.42M(-33.9%) | -$110.05M(-9.0%) |
| Mar 2004 | - | -$23.47M(+27.6%) | -$100.94M(-5.7%) |
| Dec 2003 | -$95.47M(-1.2%) | -$32.41M(-42.4%) | -$95.47M(-30.6%) |
| Sep 2003 | - | -$22.76M(-2.0%) | -$73.08M(-14.3%) |
| Jun 2003 | - | -$22.30M(-23.9%) | -$63.91M(+33.9%) |
| Mar 2003 | - | -$18.00M(-79.7%) | -$96.66M(-2.4%) |
| Dec 2002 | -$94.38M(-1432.7%) | -$10.02M(+26.3%) | -$94.38M(+1.0%) |
| Sep 2002 | - | -$13.59M(+75.3%) | -$95.30M(-80.8%) |
| Jun 2002 | - | -$55.05M(-249.9%) | -$52.71M(-992.3%) |
| Mar 2002 | - | -$15.73M(-43.9%) | -$4.83M(+21.6%) |
| Dec 2001 | -$6.16M(+73.4%) | -$10.93M(-137.7%) | -$6.16M(-438.3%) |
| Sep 2001 | - | $29.00M(+505.0%) | -$1.14M(+95.9%) |
| Jun 2001 | - | -$7.16M(+58.0%) | -$28.02M(+4.0%) |
| Mar 2001 | - | -$17.06M(-188.3%) | -$29.20M(-25.9%) |
| Dec 2000 | -$23.19M(+52.1%) | -$5.92M(-379.5%) | -$23.19M(+17.8%) |
| Sep 2000 | - | $2.12M(+125.4%) | -$28.21M(+28.4%) |
| Jun 2000 | - | -$8.33M(+24.6%) | -$39.40M(+13.2%) |
| Mar 2000 | - | -$11.05M(-1.0%) | -$45.38M(+6.2%) |
| Dec 1999 | -$48.36M(-39.3%) | -$10.94M(-20.6%) | -$48.36M(-1.8%) |
| Sep 1999 | - | -$9.07M(+36.6%) | -$47.49M(+1.0%) |
| Jun 1999 | - | -$14.31M(-1.9%) | -$47.96M(-51.9%) |
| Mar 1999 | - | -$14.04M(-39.4%) | -$31.58M(+9.0%) |
| Dec 1998 | -$34.72M(-68.9%) | -$10.07M(-5.6%) | -$34.72M(-12.5%) |
| Sep 1998 | - | -$9.54M(-560.7%) | -$30.85M(-28.5%) |
| Jun 1998 | - | $2.07M(+112.0%) | -$24.01M(+29.5%) |
| Mar 1998 | - | -$17.18M(-177.1%) | -$34.08M(-65.4%) |
| Dec 1997 | -$20.55M(+2.8%) | -$6.20M(-129.6%) | -$20.60M(-0.5%) |
| Sep 1997 | - | -$2.70M(+66.3%) | -$20.50M(+13.5%) |
| Jun 1997 | - | -$8.00M(-116.2%) | -$23.70M(-0.9%) |
| Mar 1997 | - | -$3.70M(+39.3%) | -$23.50M(-10.8%) |
| Dec 1996 | -$21.15M(-40.3%) | -$6.10M(-3.4%) | -$21.20M(+3.6%) |
| Sep 1996 | - | -$5.90M(+24.4%) | -$22.00M(-43.8%) |
| Jun 1996 | - | -$7.80M(-457.1%) | -$15.30M(-39.1%) |
| Mar 1996 | - | -$1.40M(+79.7%) | -$11.00M(+27.2%) |
| Dec 1995 | -$15.08M(+1.0%) | -$6.90M(-962.5%) | -$15.10M(-34.8%) |
| Sep 1995 | - | $800.00K(+122.9%) | -$11.20M(+20.0%) |
| Jun 1995 | - | -$3.50M(+36.4%) | -$14.00M(-0.7%) |
| Mar 1995 | - | -$5.50M(-83.3%) | -$13.90M(+8.6%) |
| Dec 1994 | -$15.23M(+0.5%) | -$3.00M(-50.0%) | -$15.20M(-7.0%) |
| Sep 1994 | - | -$2.00M(+41.2%) | -$14.20M(+2.1%) |
| Jun 1994 | - | -$3.40M(+50.0%) | -$14.50M(+15.7%) |
| Mar 1994 | - | -$6.80M(-240.0%) | -$17.20M(-12.4%) |
| Dec 1993 | -$15.30M(+21.0%) | -$2.00M(+13.0%) | -$15.30M(+13.6%) |
| Sep 1993 | - | -$2.30M(+62.3%) | -$17.70M(+7.3%) |
| Jun 1993 | - | -$6.10M(-24.5%) | -$19.10M(-9.8%) |
| Mar 1993 | - | -$4.90M(-11.4%) | -$17.40M(+10.3%) |
| Dec 1992 | -$19.37M(-1201.1%) | -$4.40M(-18.9%) | -$19.40M(-23.6%) |
| Sep 1992 | - | -$3.70M(+15.9%) | -$15.70M(-4.7%) |
| Jun 1992 | - | -$4.40M(+36.2%) | -$15.00M(-38.9%) |
| Mar 1992 | - | -$6.90M(-885.7%) | -$10.80M(-620.0%) |
| Dec 1991 | -$1.49M | -$700.00K(+76.7%) | -$1.50M(-87.5%) |
| Sep 1991 | - | -$3.00M(-1400.0%) | -$800.00K(-136.4%) |
| Jun 1991 | - | -$200.00K(-108.3%) | $2.20M(-8.3%) |
| Mar 1991 | - | $2.40M | $2.40M |
FAQ
- What is Ionis Pharmaceuticals, Inc. annual cash from operations?
- What is the all-time high annual cash from operations for Ionis Pharmaceuticals, Inc.?
- What is Ionis Pharmaceuticals, Inc. annual cash from operations year-on-year change?
- What is Ionis Pharmaceuticals, Inc. quarterly cash from operations?
- What is the all-time high quarterly cash from operations for Ionis Pharmaceuticals, Inc.?
- What is Ionis Pharmaceuticals, Inc. quarterly cash from operations year-on-year change?
- What is Ionis Pharmaceuticals, Inc. TTM cash from operations?
- What is the all-time high TTM cash from operations for Ionis Pharmaceuticals, Inc.?
- What is Ionis Pharmaceuticals, Inc. TTM cash from operations year-on-year change?
What is Ionis Pharmaceuticals, Inc. annual cash from operations?
The current annual cash from operations of IONS is -$500.95M
What is the all-time high annual cash from operations for Ionis Pharmaceuticals, Inc.?
Ionis Pharmaceuticals, Inc. all-time high annual cash from operations is $602.89M
What is Ionis Pharmaceuticals, Inc. annual cash from operations year-on-year change?
Over the past year, IONS annual cash from operations has changed by -$193.43M (-62.90%)
What is Ionis Pharmaceuticals, Inc. quarterly cash from operations?
The current quarterly cash from operations of IONS is -$131.44M
What is the all-time high quarterly cash from operations for Ionis Pharmaceuticals, Inc.?
Ionis Pharmaceuticals, Inc. all-time high quarterly cash from operations is $500.24M
What is Ionis Pharmaceuticals, Inc. quarterly cash from operations year-on-year change?
Over the past year, IONS quarterly cash from operations has changed by -$16.45M (-14.30%)
What is Ionis Pharmaceuticals, Inc. TTM cash from operations?
The current TTM cash from operations of IONS is -$247.01M
What is the all-time high TTM cash from operations for Ionis Pharmaceuticals, Inc.?
Ionis Pharmaceuticals, Inc. all-time high TTM cash from operations is $697.43M
What is Ionis Pharmaceuticals, Inc. TTM cash from operations year-on-year change?
Over the past year, IONS TTM cash from operations has changed by +$104.93M (+29.81%)