What is the current annual operating margin of PFE?

As of today, PFE annual operating margin is 27.82%

What is 1-year change in PFE annual operating margin?

PFE annual operating margin is up +7.37% year-over-year

What is 3-year change in PFE annual operating margin?

PFE annual operating margin is down -25.67% over the past 3 years

How far is PFE annual operating margin from its all-time high?

PFE annual operating margin is currently -26.87% below its historical high of 38.04% set on December 31, 2002

How does PFE annual operating margin rank versus sector peers?

PFE annual operating margin is higher than 93.66% of companies in Healthcare sector

When is PFE next annual earnings release?

As of today, the next annual earnings release for PFE has not been scheduled

When is PFE next earnings release?

The next earnings release for PFE is on November 3, 2026

Pfizer Inc. (PFE) Operating Margin History & Chart

Annual Operating Margin

27.82%1.91%+7.37%

December 31, 2025

Summary

Current Value: As of today, PFE annual operating margin is 27.82%, up +7.37% on December 31, 2025
Historical Performance: PFE annual operating margin is down -25.67% over the past 3 years, up +27.56% over the past 5 years
All-Time High Comparison: PFE annual operating margin is currently -26.87% below its historical high of 38.04% set on December 31, 2002
3-Year Low Comparison: PFE annual operating margin is +212.94% above its 3-year low of 8.89% reached on December 31, 2023
Sector Comparison: PFE annual operating margin is higher than 93.66% of companies in Healthcare sector

Operating Margin Chart

beforeafter

Performance

PFE Performance
Metric	Date	Value	1Y	3Y	5Y	15Y
Annual Operating Margin	Dec 31, 25	27.82%	+7.4%	-25.7%	+27.6%	+5.2%
Quarterly Operating Margin	Jun 28, 26	-	–	–	–	–
Price	Aug 10, 26	$27.05	+10.1%	-24.3%	-43.9%	+67.2%
PE Ratio	Aug 10, 26	35.82	+173.8%	+276.3%	+70.4%	+139.1%
Annual Revenue	Dec 31, 25	$62.58B	-1.6%	-37.6%	+50.3%	-6.7%
Annual Operating Profit	Dec 31, 25	$17.41B	+5.6%	-53.6%	+91.6%	-1.8%
Annual Gross Margin	Dec 31, 25	74.33%	+13.0%	+20.1%	+3.6%	+7.5%
Annual Net Margin	Dec 31, 25	12.44%	-1.7%	-60.3%	-22.3%	+1.6%

Operating Margin Highs

PFE Annual Operating Margin Highs Comparison
Period	High	Date	Current
3Y	37.43%	N/A	-25.7%
5Y	37.43%	Dec 31, 22	-25.7%
All	38.04%	Dec 31, 02	-26.9%

Operating Margin Lows

PFE Annual Operating Margin Lows Comparison
Period	Low	Date	Current
3Y	8.89%	Dec 31, 23	+212.9%
5Y	8.89%	Dec 31, 23	+212.9%
All	8.89%	Dec 31, 23	+212.9%

Operating Margin History

Year	Value	Change
2025	27.82%	+7.4%
2024	25.91%	+191.5%
2023	8.89%	-76.2%
2022	37.43%	+46.3%
2021	25.58%	+17.3%
2020	21.81%	+19.6%
2019	18.24%	-36.0%
2018	28.50%	+4.1%
2017	27.39%	+1.4%
2016	27.02%	-0.7%
2015	27.22%	-3.7%
2014	28.28%	-13.6%
2013	32.74%	-0.8%
2012	33.00%	+9.6%
2011	30.12%	+13.9%
2010	26.44%	-17.4%
2009	32.01%	-7.0%
2008	34.42%	+19.7%
2007	28.75%	-7.9%
2006	31.20%	+1.8%
2005	30.65%	-5.8%
2004	32.54%	+7.5%
2003	30.28%	-20.4%

Year	Value	Change
2002	38.04%	+13.0%
2001	33.66%	+15.3%
2000	29.19%	+4.5%
1999	27.92%	+4.4%
1998	26.75%	+1.4%
1997	26.37%	-1.6%
1996	26.81%	+5.6%
1995	25.39%	+6.6%
1994	23.82%	+7.0%
1993	22.27%	+11.6%
1992	19.96%	+10.6%
1991	18.04%	+9.7%
1990	16.45%	-3.6%
1989	17.07%	-9.2%
1988	18.79%	-1.7%
1987	19.12%	-10.8%
1986	21.44%	-2.0%
1985	21.87%	+1.2%
1984	21.62%	+7.0%
1983	20.20%	+15.8%
1982	17.45%	+11.1%
1981	15.71%	-2.2%
1980	16.07%	-

FAQ

What is the current annual operating margin of PFE?: As of today, PFE annual operating margin is 27.82%
What is 1-year change in PFE annual operating margin?: PFE annual operating margin is up +7.37% year-over-year
What is 3-year change in PFE annual operating margin?: PFE annual operating margin is down -25.67% over the past 3 years
How far is PFE annual operating margin from its all-time high?: PFE annual operating margin is currently -26.87% below its historical high of 38.04% set on December 31, 2002
How does PFE annual operating margin rank versus sector peers?: PFE annual operating margin is higher than 93.66% of companies in Healthcare sector
When is PFE next annual earnings release?: As of today, the next annual earnings release for PFE has not been scheduled

Operating Margin Formula

Operating Profit Margin = Operating Income

Revenue × 100%

Quarterly Operating Margin

N/A

June 28, 2026

Performance

PFE Performance
Metric	Date	Value	3M	1Y	3Y	5Y
Quarterly Operating Margin	Jun 28, 26	-	–	–	–	–
Annual Operating Margin	Dec 31, 25	27.82%	–	+7.4%	-25.7%	+27.6%
Price	Aug 10, 26	$27.05	+5.3%	+10.1%	-24.3%	-43.9%
PE Ratio	Aug 10, 26	35.82	+81.9%	+173.8%	+276.3%	+70.4%
Quarterly Revenue	Jun 28, 26	$15.03B	+4.0%	+2.6%	+15.6%	-20.4%
Quarterly Operating Profit	Jun 28, 26	-	–	–	–	–
Quarterly Gross Margin	Jun 28, 26	0.00%	-100.0%	-100.0%	-100.0%	-100.0%
Quarterly Net Margin	Jun 28, 26	-	–	–	–	–

Quarterly Operating Margin Highs

PFE Quarterly Operating Margin Highs Comparison
Period	High	Date	Current
1Y	33.21%	Sep 28, 25	N/A
3Y	33.71%	Mar 30, 25	N/A
5Y	46.67%	Jun 1, 22	N/A
All	46.67%	Jun 1, 22	N/A

Quarterly Operating Margin Lows

PFE Quarterly Operating Margin Lows Comparison
Period	Low	Date	Current
1Y	21.58%	Dec 31, 25	N/A
3Y	-22.28%	Sep 30, 23	N/A
5Y	-22.28%	Sep 30, 23	N/A
All	-219.65%	Dec 31, 88	N/A

Quarterly Operating Margin History

Month	Value	Change
Mar 2026	29.42%	+36.3%
Dec 2025	21.58%	-35.0%
Sep 2025	33.21%	+36.1%
Jun 2025	24.40%	-27.6%
Mar 2025	33.71%	+4.6%
Dec 2024	32.23%	+14.9%
Sep 2024	28.06%	+98.3%
Jun 2024	14.15%	-53.8%
Mar 2024	30.64%	+453.4%
Dec 2023	-8.67%	+61.1%
Sep 2023	-22.28%	-223.3%
Jun 2023	18.07%	-50.0%
Mar 2023	36.16%	+64.2%
Dec 2022	22.02%	-48.6%
Sep 2022	42.84%	-8.2%
Jun 2022	46.67%	+19.2%
Mar 2022	39.14%	+184.4%
Dec 2021	13.76%	-57.3%
Sep 2021	32.24%	+1.8%
Jun 2021	31.68%	-4.4%
Mar 2021	33.14%	+318.4%
Dec 2020	7.92%	-67.4%
Sep 2020	24.33%	-4.4%
Jun 2020	25.46%	-17.3%
Mar 2020	30.78%	+91.1%
Dec 2019	16.11%	-39.4%
Sep 2019	26.57%	-16.2%
Jun 2019	31.69%	-7.6%
Mar 2019	34.30%	+47.3%
Dec 2018	23.29%	-20.5%
Sep 2018	29.30%	-2.9%
Jun 2018	30.17%	-3.8%
Mar 2018	31.37%	+73.0%
Dec 2017	18.13%	-38.5%
Sep 2017	29.47%	-1.9%
Jun 2017	30.03%	-7.6%
Mar 2017	32.49%	+73.8%
Dec 2016	18.69%	-33.7%
Sep 2016	28.18%	-5.2%
Jun 2016	29.73%	-6.7%
Mar 2016	31.85%	+88.0%
Dec 2015	16.94%	-48.9%
Sep 2015	33.13%	+4.6%
Jun 2015	31.67%	+8.8%
Mar 2015	29.11%	+59.3%
Dec 2014	18.27%	-40.4%
Sep 2014	30.64%	-7.0%
Jun 2014	32.95%	+2.9%
Mar 2014	32.01%	+13.6%
Dec 2013	28.18%	-17.3%
Sep 2013	34.07%	-3.6%
Jun 2013	35.34%	+8.4%
Mar 2013	32.61%	+23.8%
Dec 2012	26.35%	-17.2%
Sep 2012	31.82%	-12.2%
Jun 2012	36.24%	+7.2%
Mar 2012	33.81%	+36.7%
Dec 2011	24.74%	-23.8%
Sep 2011	32.46%	+11.5%
Jun 2011	29.12%	-5.6%
Mar 2011	30.86%	+55.4%
Dec 2010	19.86%	-30.0%
Sep 2010	28.37%	-8.0%
Jun 2010	30.85%	+15.7%
Mar 2010	26.66%	+30.4%
Dec 2009	20.45%	-46.0%
Sep 2009	37.89%	+10.6%
Jun 2009	34.25%	-16.6%
Mar 2009	41.07%	+12.2%
Dec 2008	36.59%	+4.4%
Sep 2008	35.05%	+13.3%
Jun 2008	30.93%	-11.9%
Mar 2008	35.10%	+46.1%
Dec 2007	24.03%	+139.3%
Sep 2007	10.04%	-56.6%
Jun 2007	23.12%	-41.4%

Month	Value	Change
Mar 2007	39.44%	+75.1%
Dec 2006	22.52%	-31.7%
Sep 2006	32.98%	+4.5%
Jun 2006	31.57%	-14.0%
Mar 2006	36.72%	+29.7%
Dec 2005	28.32%	-10.2%
Sep 2005	31.55%	+14.6%
Jun 2005	27.53%	-14.7%
Mar 2005	32.29%	-13.4%
Dec 2004	37.28%	+8.1%
Sep 2004	34.48%	+27.2%
Jun 2004	27.10%	-20.7%
Mar 2004	34.18%	+27.6%
Dec 2003	26.78%	+28.5%
Sep 2003	20.84%	-15.9%
Jun 2003	24.78%	-39.6%
Mar 2003	41.03%	+14.8%
Dec 2002	35.73%	-2.6%
Sep 2002	36.70%	+13.6%
Jun 2002	32.32%	-14.5%
Mar 2002	37.80%	+35.7%
Dec 2001	27.86%	-23.1%
Sep 2001	36.24%	+6.7%
Jun 2001	33.96%	-7.7%
Mar 2001	36.80%	+35.7%
Dec 2000	27.11%	-14.6%
Sep 2000	31.76%	+17.7%
Jun 2000	26.98%	-19.1%
Mar 2000	33.37%	+53.6%
Dec 1999	21.72%	-34.7%
Sep 1999	33.24%	+17.3%
Jun 1999	28.34%	-3.7%
Mar 1999	29.44%	+39.2%
Dec 1998	21.15%	-28.4%
Sep 1998	29.52%	+10.2%
Jun 1998	26.78%	-6.6%
Mar 1998	28.66%	+19.3%
Dec 1997	24.02%	-20.1%
Sep 1997	30.07%	+25.7%
Jun 1997	23.93%	-22.8%
Mar 1997	30.98%	+14.7%
Dec 1996	27.01%	-9.3%
Sep 1996	29.79%	+38.1%
Jun 1996	21.57%	-28.5%
Mar 1996	30.16%	+22.9%
Dec 1995	24.55%	-9.9%
Sep 1995	27.24%	+26.1%
Jun 1995	21.61%	-17.7%
Mar 1995	26.26%	+20.1%
Dec 1994	21.86%	-10.5%
Sep 1994	24.43%	+18.3%
Jun 1994	20.65%	-27.6%
Mar 1994	28.52%	+264.2%
Dec 1993	-17.37%	-172.6%
Sep 1993	23.94%	-24.4%
Jun 1993	31.66%	+21.2%
Mar 1993	26.12%	+42.3%
Dec 1992	18.35%	-16.8%
Sep 1992	22.05%	+36.1%
Jun 1992	16.20%	-30.2%
Mar 1992	23.21%	+64.6%
Dec 1991	14.10%	-33.0%
Sep 1991	21.06%	+39.3%
Jun 1991	15.12%	-31.2%
Mar 1991	21.98%	+86.3%
Dec 1990	11.80%	-41.0%
Sep 1990	19.99%	+42.9%
Jun 1990	13.99%	-32.1%
Mar 1990	20.61%	+109.6%
Dec 1989	-214.81%	+2.2%
Dec 1988	-219.65%	-3.6%
Dec 1987	-212.03%	-4.8%
Dec 1986	-202.37%	-2.6%
Dec 1985	-197.24%	+7.2%
Dec 1984	-212.64%	-

FAQ

When is PFE next earnings release?: The next earnings release for PFE is on November 3, 2026

Operating Margin Formula

Operating Profit Margin = Operating Income

Revenue × 100%

Data Sources & References

PFE Official Website www.pfizer.com
Most Recent Annual Report (10-K) www.sec.gov/Archives/edgar/data/78003/000007800326000005/0000078003-26-000005-index.htm
PFE Profile on Yahoo Finance finance.yahoo.com/quote/PFE
PFE Profile on NASDAQ.com www.nasdaq.com/market-activity/stocks/pfe