What is the current annual net margin of PFE?

As of today, PFE annual net margin is 12.44%

What is 1-year change in PFE annual net margin?

PFE annual net margin is down -1.66% year-over-year

What is 3-year change in PFE annual net margin?

PFE annual net margin is down -60.26% over the past 3 years

How far is PFE annual net margin from its all-time high?

PFE annual net margin is currently -69.39% below its historical high of 40.64% set on December 31, 2017

How does PFE annual net margin rank versus sector peers?

PFE annual net margin is higher than 90.24% of companies in Healthcare sector

When is PFE next annual earnings release?

As of today, the next annual earnings release for PFE has not been scheduled

What is the current quarterly net margin of PFE?

As of today, PFE quarterly net margin is -9.34%

What is PFE quarterly net margin most recent change?

PFE quarterly net margin was down -143.81% on December 31, 2025

What is 1-year change in PFE quarterly net margin?

PFE quarterly net margin is down -504.33% year-over-year

How far is PFE quarterly net margin from its all-time high?

PFE quarterly net margin is currently -110.42% below its historical high of 89.67% set on December 31, 2017

How does PFE quarterly net margin rank versus sector peers?

PFE quarterly net margin is higher than 57.66% of companies in Healthcare sector

When is PFE next earnings release?

The next earnings release for PFE is on April 28, 2026

Pfizer Inc. (PFE) Net Margin History & Chart Since 1980

Annual Net Margin

12.44%0.21%-1.66%

December 31, 2025

Summary

Current Value: As of today, PFE annual net margin is 12.44%, down -1.66% on December 31, 2025
Historical Performance: PFE annual net margin is down -60.26% over the past 3 years, down -22.25% over the past 5 years
All-Time High Comparison: PFE annual net margin is currently -69.39% below its historical high of 40.64% set on December 31, 2017
3-Year Low Comparison: PFE annual net margin is +240.82% above its 3-year low of 3.65% reached on December 31, 2023
Sector Comparison: PFE annual net margin is higher than 90.24% of companies in Healthcare sector

Net Margin Chart

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Series

Performance

PFE Performance
Metric	Date	Value	1Y	3Y	5Y	15Y
Annual Net Margin	Dec 31, 25	12.44%	-1.7%	-60.3%	-22.3%	+1.6%
Quarterly Net Margin	Dec 31, 25	-9.34%	-504.3%	-145.4%	-271.4%	-156.5%
Price	Feb 13, 26	$27.73	+8.2%	-37.0%	-20.1%	+55.2%
PE Ratio	Feb 13, 26	20.46	+12.2%	+154.5%	-4.0%	+18.0%
Annual Revenue	Dec 31, 25	$62.58B	-1.6%	-37.6%	+50.3%	-6.7%
Annual Net Income	Dec 31, 25	$7.79B	-3.3%	-75.2%	+16.8%	-5.2%
Annual Gross Margin	Dec 31, 25	74.33%	+13.0%	+20.1%	+3.6%	+7.5%
Annual Operating Margin	Dec 31, 25	27.82%	+7.4%	-25.7%	+27.6%	+5.2%

Net Margin Highs

PFE Annual Net Margin Highs Comparison
Period	High	Date	Current
3Y	31.30%	N/A	-60.3%
5Y	31.30%	Dec 31, 22	-60.3%
All	40.64%	Dec 31, 17	-69.4%

Net Margin Lows

PFE Annual Net Margin Lows Comparison
Period	Low	Date	Current
3Y	3.65%	Dec 31, 23	+240.8%
5Y	3.65%	Dec 31, 23	+240.8%
All	3.63%	Dec 31, 03	+242.7%

Net Margin History

Year	Value	Change
2025	12.44%	-1.7%
2024	12.65%	+246.6%
2023	3.65%	-88.3%
2022	31.30%	+13.3%
2021	27.63%	+72.7%
2020	16.00%	-39.4%
2019	26.39%	+26.6%
2018	20.84%	-48.7%
2017	40.64%	+196.9%
2016	13.69%	-4.1%
2015	14.28%	-22.3%
2014	18.38%	-16.9%
2013	22.12%	+34.1%
2012	16.50%	+28.1%
2011	12.88%	+5.2%
2010	12.24%	-29.1%
2009	17.26%	+3.5%
2008	16.67%	-2.2%
2007	17.05%	-25.3%
2006	22.82%	+41.9%
2005	16.08%	-25.6%
2004	21.60%	+495.0%
2003	3.63%	-87.2%

Year	Value	Change
2002	28.38%	+17.2%
2001	24.21%	+90.5%
2000	12.71%	-35.6%
1999	19.74%	+37.3%
1998	14.38%	-18.9%
1997	17.74%	+3.9%
1996	17.07%	+10.1%
1995	15.51%	-1.4%
1994	15.73%	+78.1%
1993	8.83%	-41.8%
1992	15.16%	+45.2%
1991	10.44%	-16.9%
1990	12.57%	+4.1%
1989	12.08%	-18.1%
1988	14.75%	+4.6%
1987	14.10%	-5.0%
1986	14.84%	+2.1%
1985	14.54%	+9.0%
1984	13.34%	+10.4%
1983	12.08%	+23.4%
1982	9.79%	+13.8%
1981	8.60%	-0.6%
1980	8.65%	-

FAQ

What is the current annual net margin of PFE?
As of today, PFE annual net margin is 12.44%
What is 1-year change in PFE annual net margin?
PFE annual net margin is down -1.66% year-over-year
What is 3-year change in PFE annual net margin?
PFE annual net margin is down -60.26% over the past 3 years
How far is PFE annual net margin from its all-time high?
PFE annual net margin is currently -69.39% below its historical high of 40.64% set on December 31, 2017
How does PFE annual net margin rank versus sector peers?
PFE annual net margin is higher than 90.24% of companies in Healthcare sector
When is PFE next annual earnings release?
As of today, the next annual earnings release for PFE has not been scheduled

Quarterly Net Margin

-9.34%30.66%-143.81%

December 31, 2025

Summary

Current Value: As of today, PFE quarterly net margin is -9.34%, down -143.81% on December 31, 2025
Historical Performance: PFE quarterly net margin is down -504.33% year-over-year, down -145.36% over the past 3 years
All-Time High Comparison: PFE quarterly net margin is currently -110.42% below its historical high of 89.67% set on December 31, 2017
3-Year Low Comparison: PFE quarterly net margin is +59.20% above its 3-year low of -22.89% reached on December 31, 2023
Sector Comparison: PFE quarterly net margin is higher than 57.66% of companies in Healthcare sector

Performance

PFE Performance
Metric	Date	Value	3M	1Y	3Y	5Y
Quarterly Net Margin	Dec 31, 25	-9.34%	-143.8%	-504.3%	-145.4%	-271.4%
Annual Net Margin	Dec 31, 25	12.44%	–	-1.7%	-60.3%	-22.3%
Price	Feb 13, 26	$27.73	+7.5%	+8.2%	-37.0%	-20.1%
PE Ratio	Feb 13, 26	20.46	+36.1%	+12.2%	+154.5%	-4.0%
Quarterly Revenue	Dec 31, 25	$17.56B	+5.4%	-1.2%	-27.7%	+50.9%
Quarterly Net Income	Dec 31, 25	-$1.64B	-146.2%	-499.0%	-132.8%	-358.7%
Quarterly Gross Margin	Dec 31, 25	69.97%	+4.2%	-4.2%	+26.9%	+2.5%
Quarterly Operating Margin	Dec 31, 25	21.01%	-36.7%	-34.8%	-4.6%	+165.3%

Quarterly Net Margin Highs

PFE Quarterly Net Margin Highs Comparison
Period	High	Date	Current
1Y	21.68%	Mar 30, 25	-143.1%
3Y	30.05%	Mar 31, 23	-131.1%
5Y	38.19%	Sep 1, 22	-124.5%
All	89.67%	Dec 31, 17	-110.4%

Quarterly Net Margin Lows

PFE Quarterly Net Margin Lows Comparison
Period	Low	Date	Current
1Y	-9.34%	Dec 31, 25	at low
3Y	-22.89%	Dec 31, 23	+59.2%
5Y	-22.89%	Dec 31, 23	+59.2%
All	-36.78%	Jun 29, 03	+74.6%

Quarterly Net Margin History

Month	Value	Change
Dec 2025	-9.34%	-143.8%
Sep 2025	21.32%	+7.6%
Jun 2025	19.81%	-8.6%
Mar 2025	21.68%	+838.5%
Dec 2024	2.31%	-90.9%
Sep 2024	25.31%	>+9,900.0%
Jun 2024	0.23%	-98.9%
Mar 2024	21.02%	+191.8%
Dec 2023	-22.89%	-29.3%
Sep 2023	-17.70%	-198.4%
Jun 2023	17.99%	-40.1%
Mar 2023	30.05%	+45.9%
Dec 2022	20.59%	-46.1%
Sep 2022	38.19%	+7.3%
Jun 2022	35.60%	+16.0%
Mar 2022	30.70%	+104.5%
Dec 2021	15.01%	-55.9%
Sep 2021	34.00%	+10.3%
Jun 2021	30.82%	-8.4%
Mar 2021	33.65%	+517.4%
Dec 2020	5.45%	-38.9%
Sep 2020	8.92%	-66.2%
Jun 2020	26.40%	+7.2%
Mar 2020	24.63%	+1,054.7%
Dec 2019	-2.58%	-104.3%
Sep 2019	60.57%	+58.9%
Jun 2019	38.12%	+28.6%
Mar 2019	29.65%	+1,182.1%
Dec 2018	-2.74%	-108.9%
Sep 2018	30.91%	+7.3%
Jun 2018	28.81%	+4.2%
Mar 2018	27.66%	-69.2%
Dec 2017	89.67%	+313.2%
Sep 2017	21.70%	-9.1%
Jun 2017	23.86%	-2.6%
Mar 2017	24.49%	+337.3%
Dec 2016	5.60%	-46.1%
Sep 2016	10.39%	-33.7%
Jun 2016	15.68%	-33.1%
Mar 2016	23.44%	+2,086.4%
Dec 2015	-1.18%	-106.7%
Sep 2015	17.62%	-20.7%
Jun 2015	22.23%	+1.6%
Mar 2015	21.87%	+128.3%
Dec 2014	9.58%	-55.8%
Sep 2014	21.65%	-5.3%
Jun 2014	22.87%	+14.6%
Mar 2014	19.95%	+2.8%
Dec 2013	19.41%	-5.2%
Sep 2013	20.47%	-25.7%
Jun 2013	27.56%	+34.8%
Mar 2013	20.45%	+106.8%
Dec 2012	9.89%	-55.6%
Sep 2012	22.25%	+4.9%
Jun 2012	21.21%	+81.3%
Mar 2012	11.70%	+31.2%
Dec 2011	8.92%	-37.0%
Sep 2011	14.16%	-7.1%
Jun 2011	15.24%	+13.1%
Mar 2011	13.48%	-18.5%
Dec 2010	16.53%	+205.0%
Sep 2010	5.42%	-62.2%
Jun 2010	14.35%	+18.2%
Mar 2010	12.14%	+164.5%
Dec 2009	4.59%	-81.5%
Sep 2009	24.77%	+20.2%
Jun 2009	20.60%	-18.0%
Mar 2009	25.11%	+1,242.8%
Dec 2008	1.87%	-90.1%
Sep 2008	18.87%	-17.2%
Jun 2008	22.80%	-3.3%
Mar 2008	23.58%	+10.5%
Dec 2007	21.34%	+220.9%
Sep 2007	6.65%	-45.3%
Jun 2007	12.15%	-54.9%
Mar 2007	26.97%	+128.0%
Dec 2006	11.83%	-55.2%
Sep 2006	26.42%	+35.3%
Jun 2006	19.53%	-42.8%
Mar 2006	34.14%	+68.3%
Dec 2005	20.28%	+54.1%
Sep 2005	13.16%	-52.9%
Jun 2005	27.96%	+1,231.4%
Mar 2005	2.10%	-89.3%

Month	Value	Change
Dec 2004	19.59%	-23.9%
Sep 2004	25.73%	+11.0%
Jun 2004	23.19%	+24.8%
Mar 2004	18.58%	+336.2%
Dec 2003	4.26%	-76.2%
Sep 2003	17.92%	+148.7%
Jun 2003	-36.78%	-227.4%
Mar 2003	28.86%	-0.7%
Dec 2002	29.06%	+7.8%
Sep 2002	26.95%	+10.6%
Jun 2002	24.36%	-13.6%
Mar 2002	28.20%	+30.0%
Dec 2001	21.69%	-17.6%
Sep 2001	26.31%	+12.3%
Jun 2001	23.43%	-7.4%
Mar 2001	25.30%	+45.3%
Dec 2000	17.41%	-8.0%
Sep 2000	18.93%	+15.5%
Jun 2000	16.39%	-40.1%
Mar 2000	27.37%	+27.1%
Dec 1999	21.53%	+22.4%
Sep 1999	17.59%	-3.7%
Jun 1999	18.26%	-12.1%
Mar 1999	20.78%	+165.4%
Dec 1998	7.83%	-49.4%
Sep 1998	15.47%	-10.6%
Jun 1998	17.31%	-16.6%
Mar 1998	20.75%	+14.3%
Dec 1997	18.16%	-16.3%
Sep 1997	21.70%	+38.3%
Jun 1997	15.69%	-21.7%
Mar 1997	20.05%	-31.7%
Dec 1996	29.34%	+60.0%
Sep 1996	18.34%	+23.8%
Jun 1996	14.81%	-23.2%
Mar 1996	19.28%	+28.8%
Dec 1995	14.97%	-10.6%
Sep 1995	16.75%	+31.5%
Jun 1995	12.74%	-27.2%
Mar 1995	17.50%	+20.5%
Dec 1994	14.52%	-10.5%
Sep 1994	16.22%	+21.3%
Jun 1994	13.37%	-28.5%
Mar 1994	18.69%	+28.7%
Dec 1993	14.52%	+226.9%
Sep 1993	-11.44%	-178.8%
Jun 1993	14.51%	-17.7%
Mar 1993	17.62%	+2,281.1%
Dec 1992	0.74%	-95.5%
Sep 1992	16.28%	+35.3%
Jun 1992	12.03%	-28.2%
Mar 1992	16.75%	>+9,900.0%
Dec 1991	0.05%	-99.7%
Sep 1991	15.49%	+41.1%
Jun 1991	10.98%	-30.4%
Mar 1991	15.77%	+81.9%
Dec 1990	8.67%	-41.5%
Sep 1990	14.81%	+46.5%
Jun 1990	10.11%	-40.5%
Mar 1990	17.00%	+191.6%
Dec 1989	5.83%	-61.4%
Sep 1989	15.12%	+45.1%
Jun 1989	10.42%	-37.9%
Mar 1989	16.77%	+62.0%
Dec 1988	10.35%	-34.0%
Sep 1988	15.68%	-1.7%
Jun 1988	15.95%	-5.8%
Mar 1988	16.94%	+58.2%
Dec 1987	10.71%	-25.2%
Sep 1987	14.32%	-0.1%
Jun 1987	14.33%	-16.4%
Mar 1987	17.15%	+25.9%
Dec 1986	13.62%	-10.3%
Sep 1986	15.18%	+8.7%
Jun 1986	13.96%	-14.7%
Mar 1986	16.36%	+24.2%
Dec 1985	13.17%	-14.2%
Sep 1985	15.35%	+11.9%
Jun 1985	13.72%	-11.9%
Mar 1985	15.58%	+16.4%
Dec 1984	13.38%	-1.0%
Sep 1984	13.51%	+12.8%
Jun 1984	11.98%	-13.7%
Mar 1984	13.88%	-

FAQ

What is the current quarterly net margin of PFE?
As of today, PFE quarterly net margin is -9.34%
What is PFE quarterly net margin most recent change?
PFE quarterly net margin was down -143.81% on December 31, 2025
What is 1-year change in PFE quarterly net margin?
PFE quarterly net margin is down -504.33% year-over-year
How far is PFE quarterly net margin from its all-time high?
PFE quarterly net margin is currently -110.42% below its historical high of 89.67% set on December 31, 2017
How does PFE quarterly net margin rank versus sector peers?
PFE quarterly net margin is higher than 57.66% of companies in Healthcare sector
When is PFE next earnings release?
The next earnings release for PFE is on April 28, 2026

Net Margin Formula

Net Margin = Net Income

Revenue × 100%

Data Sources & References

PFE Official Website www.pfizer.com
Most Recent Quarterly Report (10-Q) www.sec.gov/Archives/edgar/data/78003/000007800326000005/0000078003-26-000005-index.htm
Most Recent Annual Report (10-K) www.sec.gov/Archives/edgar/data/78003/000007800326000005/0000078003-26-000005-index.htm
PFE Profile on Yahoo Finance finance.yahoo.com/quote/PFE
PFE Profile on NASDAQ.com www.nasdaq.com/market-activity/stocks/pfe