Profile
| Metric | Value |
|---|---|
| Full Name | Upstream Bio, Inc. |
| Ticker | NASDAQ: UPB |
| Exchange | NASDAQ |
| Sector | Healthcare |
| Industry | Biotechnology |
| Country | United States |
| IPO | |
| Indexes | Not included |
| Website | upstreambio.com |
| Employees | 52 |
Key Metrics
| Metric | Date | Value |
|---|---|---|
| Price | $28.08 | |
| Price, 1D Change | +8.54% | |
| Market Cap | $2B | |
| - | ||
| PE Ratio | - | |
| Beta | 0.89 | |
| Revenue | $2M | |
| Revenue, 1Y Change | -0.42% | |
| EPS | -$1.43 | |
| EPS, 1Y Change | -99.69% |
Chart
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Series
SUGGESTED SERIES
Events
| Metric | Date | Value |
|---|---|---|
| Next Earnings | ||
| Last Qtr. Earnings | ||
| Last Ann. Earnings | ||
| Last Ex-Dividend | N/A | N/A |
| Next Ex-Dividend | N/A | N/A |
| Last Split | N/A | N/A |
| Next Split | N/A | N/A |
| Last Ticker Change | N/A | N/A |
| Next Ticker Change | N/A | N/A |
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Estimates
| Metric | Date | Value |
|---|---|---|
| EPS | -$1.43 | |
| EPS Estimate | -$2.58 | |
| EPS Est. Change | -80.74% | |
| Revenue | $2.37M | |
| Revenue Estimate | $2.67M | |
| Revenue Est. Change | +12.53% | |
| Current Price | $28.08 | |
| Price Target | - | $43.00 |
| Price Tgt. Change | - | +53.13% |
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EPS
| Year | Estimate | Reported | Surprise / Exp. |
|---|---|---|---|
| -$7.68 | -$1.43 | +81.43% | |
| -$2.58 | N/A | -80.74% | |
| -$3.20 | N/A | -124.45% |
Revenue
| Year | Estimate | Reported | Surprise / Exp. |
|---|---|---|---|
| $2.14M | $2.37M | +10.66% | |
| $2.67M | N/A | +12.53% | |
| $1.32M | N/A | -44.47% |
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Performance
| Metric | Date | Value |
|---|---|---|
| Price, 1Y | +73.65% | |
| Price, 3Y | - | |
| Market Cap, 1Y | +74.65% | |
| Market Cap, 3Y | - | |
| Revenue, 1Y | -0.42% | |
| Revenue, 3Y | +95.54% | |
| EPS, 1Y | -99.69% | |
| EPS, 3Y | -220.05% |
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Technical Indicators
| Metric | Date | Value |
|---|---|---|
| Current Price | $28.08 | |
| SMA 200 | $16.55 | |
| SMA 200 vs Price | -41.08% | |
| SMA 50 | $26.66 | |
| SMA 50 vs Price | -5.06% | |
| Beta | 0.89 | |
| ATR | $1.75 | |
| 14-Day RSI | 52.31 | |
| 10-Day Volatility | 64.70% | |
| 1-Year Volatility | 81.72% |
Dividends
| Metric | Date | Value |
|---|---|---|
| N/A | - | |
| Upcoming | N/A | N/A |
| - | ||
| - | ||
| Dividends Paid | $0.00 | |
| Payout Ratio | 0.00% |
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Income & Profitability
| Metric | Date | Value |
|---|---|---|
| Revenue | $2.37M | |
| EPS | -$1.43 | |
| Gross Profit | $2.28M | |
| Gross Margin | 96.24% | |
| Operating Profit | -$77.76M | |
| Operating Margin | -3,281.18% | |
| Net Income | -$62.81M | |
| Net Margin | -2,650.04% | |
| EBITDA | -$77.68M |
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Financial Health
| Metric | Date | Value |
|---|---|---|
| Debt To Equity | 0.00 | |
| Current Ratio | 44.63 | |
| Quick Ratio | 44.63 | |
| - | ||
| 2 | ||
| Altman Z-Score | 76.62 |
Valuations
| Metric | Date | Value |
|---|---|---|
| PE Ratio | - | |
| PS Ratio | 540.83 | |
| PB Ratio | 4.00 | |
| EV/EBITDA | -8.14 | |
| Enterprise Value | N/A | - |
Balance Sheet
| Metric | Date | Value |
|---|---|---|
| Book Value | $469.85M | |
| Cash & Equivalents | $325.89M | |
| Total Assets | $481.72M | |
| Current Assets | $479.16M | |
| Total Liabilities | $11.87M | |
| Current Liabilities | $10.74M | |
| Total Debt | $1.83M | |
| Short Term Debt | $704.00K | |
| Accounts Payable | $4.04M |
Expenses
| Metric | Date | Value |
|---|---|---|
| Total Expenses | $80.13M | |
| Operating Expenses | $80.13M | |
| Cost Of Goods Sold | $89.00K | |
| SG&A | $17.17M | |
| D&A | $89.00K | |
| Interest Expense | $0.00 | |
| Income Tax | $0.00 |
Cash Flow
| Metric | Date | Value |
|---|---|---|
| CFO | -$59.17M | |
| CFI | -$59.49M | |
| CFF | $418.91M | |
| Capex | $511.00K | |
| Free Cash Flow | -$59.68M |
Recent analyst updates
| Metric | Date | Value |
|---|---|---|
| Mizuho | ||
| LifeSci Capital | ||
| Evercore ISI Group | ||
| Truist Securities | ||
| William Blair | ||
| TD Cowen | ||
| Piper Sandler | ||
| JP Morgan |
Analyst sentiment
Institutional ownership
Screeners with UPB
Data Sources & References
- UPB Official Website upstreambio.com
- Most Recent Quarterly Report (10-Q) www.sec.gov/Archives/edgar/data/2022626/000119312525265713/0001193125-25-265713-index.htm
- Most Recent Annual Report (10-K) www.sec.gov/Archives/edgar/data/2022626/000095017025037621/0000950170-25-037621-index.htm
- UPB Profile on Yahoo Finance finance.yahoo.com/quote/UPB
- UPB Profile on NASDAQ.com www.nasdaq.com/market-activity/stocks/upb
FAQ
What is the ticker symbol for Upstream Bio, Inc.?
The ticker symbol for Upstream Bio, Inc. is NASDAQ:UPB
Does Upstream Bio, Inc. pay dividends?
No, Upstream Bio, Inc. does not pay dividends
What sector is Upstream Bio, Inc. in?
Upstream Bio, Inc. is in the Healthcare sector
What industry is Upstream Bio, Inc. in?
Upstream Bio, Inc. is in the Biotechnology industry
What country is Upstream Bio, Inc. based in?
Upstream Bio, Inc. is headquartered in United States
When did Upstream Bio, Inc. go public?
Upstream Bio, Inc. initial public offering (IPO) was on October 11, 2024
Is Upstream Bio, Inc. in the S&P 500?
No, Upstream Bio, Inc. is not included in the S&P 500 index
Is Upstream Bio, Inc. in the NASDAQ 100?
No, Upstream Bio, Inc. is not included in the NASDAQ 100 index
Is Upstream Bio, Inc. in the Dow Jones?
No, Upstream Bio, Inc. is not included in the Dow Jones index
When was Upstream Bio, Inc. last earnings report?
Upstream Bio, Inc.'s most recent earnings report was on November 5, 2025
When does Upstream Bio, Inc. report earnings?
The next expected earnings date for Upstream Bio, Inc. is March 11, 2026