Upstream Bio, Inc. (UPB)

Summary

Current Price
As of today, UPB price is $8.45, up +0.84% in the most recent trading session on
Current Price All-Time High
UPB price is currently -74.91% below its historical high of $33.68 set on
Market Cap
UPB current market cap is $457M, up +5.75% over the past 365 days
PE Ratio
UPB PE ratio is unknown
Revenue
UPB current annual revenue is $2.37M, down -0.42% year-over-year
Next Earnings
The next earnings release for UPB is on

Profile

Company profile for Upstream Bio, Inc. (UPB)
MetricValue
Full NameUpstream Bio, Inc.
TickerNASDAQ: UPB
ExchangeNASDAQ
SectorHealthcare
IndustryBiotechnology
CountryUnited States
IPO
IndexesNot included
Websiteupstreambio.com
Employees52

Key Metrics

Upstream Bio, Inc. Key Details
MetricDateValue
Price$8.45
Price, 1D Change+0.84%
$457M
-
-
0.84
$2M
Revenue, 1Y Change-0.42%
-$1.43
EPS, 1Y Change-99.69%

Chart

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Series
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Upstream Bio, Inc. chart

Events

Upstream Bio, Inc. Events
MetricDateValue
Next Earnings
Last Qtr. Earnings
Last Ann. Earnings
Last Ex-DividendN/AN/A
Next Ex-DividendN/AN/A
Last SplitN/AN/A
Next SplitN/AN/A
Last Ticker ChangeN/AN/A
Next Ticker ChangeN/AN/A

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Estimates

UPB Estimates
MetricDateValue
-$1.43
EPS Estimate-$2.58
EPS Est. Change-80.76%
$2.37M
Revenue Estimate$2.68M
Revenue Est. Change+13.23%
Current Price$8.45
Price Target-$44.00
Price Tgt. Change-+420.71%

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EPS

UPB EPS reported versus estimate values
YearEstimateReportedSurprise / Exp.
-$7.68-$1.43+81.43%
-$2.58N/A-80.76%
-$3.11N/A-118.39%
UPB EPS reported versus estimate values chart

Revenue

UPB revenue reported versus estimate values chart
YearEstimateReportedSurprise / Exp.
$2.14M$2.37M+10.66%
$2.68MN/A+13.23%
$1.31MN/A-44.55%
UPB revenue reported versus estimate values chart

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Performance

UPB Performance
MetricDateValue
Price, 1Y+4.97%
Price, 3Y-
+5.75%
-
-0.42%
+95.54%
-99.69%
-220.05%

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Technical Indicators

UPB Technical Indicators
MetricDateValue
Current Price$8.45
$19.12
SMA 200 vs Price+126.26%
$18.94
SMA 50 vs Price+124.16%
0.84
$1.07
30.66
105.73%
96.63%

Dividends

UPB Dividends
MetricDateValue
N/A-
UpcomingN/AN/A
-
-
$0.00
0.00%

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Income & Profitability

UPB Income & Profitability
MetricDateValue
$2.37M
-$1.43
$2.28M
96.24%
-$77.76M
-3,281.18%
-$62.81M
-2,650.04%
-$77.68M

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Financial Health

UPB Financial Health
MetricDateValue
0.00
44.63
44.63
-
2
23.17

Valuations

UPB Valuations
MetricDateValue
-
163.14
1.21
-0.61
N/A-

Balance Sheet

UPB Balance Sheet
MetricDateValue
$469.85M
$325.89M
$481.72M
$479.16M
$11.87M
$10.74M
$1.83M
$704.00K
$4.04M

Expenses

UPB Expenses
MetricDateValue
$80.13M
$80.13M
$89.00K
$17.17M
$89.00K
$0.00
$0.00

Cash Flow

UPB Cash Flow
MetricDateValue
-$59.17M
-$59.49M
$418.91M
$511.00K
-$59.68M

Recent analyst updates

UPB Recent analyst updates
MetricDateValue
Mizuho
LifeSci Capital
Evercore ISI Group
Truist Securities
William Blair
TD Cowen
Piper Sandler
JP Morgan

Analyst sentiment

Sentiment over the past month
UPB analyst sentiment distribution chart

Institutional ownership

Largest institutional holders by ownership percentage
UPB institutional ownership distribution chart

Screeners with UPB

FAQ

  • What is the ticker symbol for Upstream Bio, Inc.?

    The ticker symbol for Upstream Bio, Inc. is NASDAQ:UPB

  • Does Upstream Bio, Inc. pay dividends?

    No, Upstream Bio, Inc. does not pay dividends

  • What sector is Upstream Bio, Inc. in?

    Upstream Bio, Inc. is in the Healthcare sector

  • What industry is Upstream Bio, Inc. in?

    Upstream Bio, Inc. is in the Biotechnology industry

  • What country is Upstream Bio, Inc. based in?

    Upstream Bio, Inc. is headquartered in United States

  • When did Upstream Bio, Inc. go public?

    Upstream Bio, Inc. initial public offering (IPO) was on October 11, 2024

  • Is Upstream Bio, Inc. in the S&P 500?

    No, Upstream Bio, Inc. is not included in the S&P 500 index

  • Is Upstream Bio, Inc. in the NASDAQ 100?

    No, Upstream Bio, Inc. is not included in the NASDAQ 100 index

  • Is Upstream Bio, Inc. in the Dow Jones?

    No, Upstream Bio, Inc. is not included in the Dow Jones index

  • When was Upstream Bio, Inc. last earnings report?

    Upstream Bio, Inc.'s most recent earnings report was on November 5, 2025

  • When does Upstream Bio, Inc. report earnings?

    The next expected earnings date for Upstream Bio, Inc. is March 24, 2026

Data Sources & References

  1. UPB Official Website upstreambio.com
  2. Most Recent Quarterly Report (10-Q) www.sec.gov/Archives/edgar/data/2022626/000119312525265713/0001193125-25-265713-index.htm
  3. Most Recent Annual Report (10-K) www.sec.gov/Archives/edgar/data/2022626/000095017025037621/0000950170-25-037621-index.htm
  4. UPB Profile on Yahoo Finance finance.yahoo.com/quote/UPB
  5. UPB Profile on NASDAQ.com www.nasdaq.com/market-activity/stocks/upb