Annual Operating Profit
-$77.76M$37.65M-93.86%
Summary
- Current Value
- As of today, UPB annual operating profit is -$77.76M, down -93.86% on
- Historical Performance
- UPB annual operating profit is down -225.25% over the past 3 years, and down -225.25% over the past 5 years
- All-Time High Comparison
- UPB annual operating profit is currently -225.25% below its historical high of -$23.91M set on
- 3-Year Low Comparison
- UPB annual operating profit is at its 3-year low
- Sector Comparison
- UPB annual operating profit is higher than 22.48% of companies in Healthcare sector
Operating Profit Chart
Add series to chart1/6
Series
SUGGESTED SERIES
Performance
| Metric | Date | Value | 1Y | 3Y | 5Y | 15Y |
|---|---|---|---|---|---|---|
| Annual Operating Profit | -$77.76M | -93.9% | -225.3% | -225.3% | -225.3% | |
| Quarterly Operating Profit | -$37.83M | -100.3% | -303.1% | -303.1% | -303.1% | |
| TTM Operating Profit | -$140.51M | -113.6% | -1397.0% | -1397.0% | -1397.0% | |
| Price | $27.54 | +70.1% | – | – | – | |
| PE Ratio | - | – | – | – | – | |
| Annual Revenue | $2.37M | -0.4% | +95.5% | +95.5% | +95.5% | |
| Annual EPS | -$1.43 | -99.7% | -220.1% | -220.1% | -220.1% | |
| Annual Gross Profit | $2.28M | -1.7% | +89.3% | +89.3% | +89.3% | |
| Annual Operating Expenses | $80.13M | +88.6% | +219.0% | +219.0% | +219.0% |
Operating Profit Highs
| Period | High | Date | Current |
|---|---|---|---|
| 3Y | -$23.91M | N/A | -225.3% |
| 5Y | -$23.91M | -225.3% | |
| All | -$23.91M | -225.3% |
Operating Profit Lows
| Period | Low | Date | Current |
|---|---|---|---|
| 3Y | -$77.76M | at low | |
| 5Y | -$77.76M | at low | |
| All | -$77.76M | at low |
Operating Profit History
| Year | Value | Change |
|---|---|---|
| -$77.76M | -93.9% | |
| -$40.11M | -67.8% |
| Year | Value | Change |
|---|---|---|
| -$23.91M | - |
FAQ
What is the current annual operating profit of UPB?
As of today, UPB annual operating profit is -$77.76M
What is 1-year change in UPB annual operating profit?
UPB annual operating profit is down -93.86% year-over-year
What is 3-year change in UPB annual operating profit?
UPB annual operating profit is down -225.25% over the past 3 years
How far is UPB annual operating profit from its all-time high?
UPB annual operating profit is currently -225.25% below its historical high of -$23.91M set on December 1, 2022
How does UPB annual operating profit rank versus sector peers?
UPB annual operating profit is higher than 22.48% of companies in Healthcare sector
When is UPB next annual earnings release?
The next annual earnings release for UPB is on
Quarterly Operating Profit
-$37.83M$6.51M+14.69%
Summary
- Current Value
- As of today, UPB quarterly operating profit is -$37.83M, up +14.69% on
- Historical Performance
- UPB quarterly operating profit is down -100.25% year-over-year, and down -303.09% over the past 3 years
- All-Time High Comparison
- UPB quarterly operating profit is currently -303.09% below its historical high of -$9.39M set on
- 3-Year Low Comparison
- UPB quarterly operating profit is +14.69% above its 3-year low of -$44.35M reached on
- Sector Comparison
- UPB quarterly operating profit is higher than 12.50% of companies in Healthcare sector
Performance
| Metric | Date | Value | 3M | 1Y | 3Y | 5Y |
|---|---|---|---|---|---|---|
| Quarterly Operating Profit | -$37.83M | +14.7% | -100.3% | -303.1% | -303.1% | |
| Annual Operating Profit | -$77.76M | – | -93.9% | -225.3% | -225.3% | |
| TTM Operating Profit | -$140.51M | -15.6% | -113.6% | -1397.0% | -1397.0% | |
| Price | $27.54 | +45.6% | +70.1% | – | – | |
| PE Ratio | - | – | – | – | – | |
| Quarterly Revenue | $683.00K | -27.1% | +12.5% | +10.0% | +10.0% | |
| Quarterly EPS | -$0.63 | +15.8% | -59.5% | -263.6% | -263.6% | |
| Quarterly Gross Profit | $652.00K | -25.9% | +9.9% | – | – | |
| Quarterly Operating Expenses | $38.49M | -14.9% | +97.5% | +284.6% | +284.6% |
Quarterly Operating Profit Highs
| Period | High | Date | Current |
|---|---|---|---|
| 1Y | -$26.32M | N/A | -43.8% |
| 3Y | -$9.39M | -303.1% | |
| 5Y | -$9.39M | -303.1% | |
| All | -$9.39M | -303.1% |
Quarterly Operating Profit Lows
| Period | Low | Date | Current |
|---|---|---|---|
| 1Y | -$44.35M | +14.7% | |
| 3Y | -$44.35M | +14.7% | |
| 5Y | -$44.35M | +14.7% | |
| All | -$44.35M | +14.7% |
Quarterly Operating Profit History
| Month | Value | Change |
|---|---|---|
| -$37.83M | +14.7% | |
| -$44.35M | -38.5% | |
| -$32.01M | -21.6% | |
| -$26.32M | -39.3% | |
| -$18.89M | -7.7% |
| Month | Value | Change |
|---|---|---|
| -$17.54M | -16.8% | |
| -$15.01M | -4.8% | |
| -$14.33M | -52.7% | |
| -$9.39M | - |
FAQ
What is the current quarterly operating profit of UPB?
As of today, UPB quarterly operating profit is -$37.83M
What is UPB quarterly operating profit most recent change?
UPB quarterly operating profit was up +14.69% on September 30, 2025
What is 1-year change in UPB quarterly operating profit?
UPB quarterly operating profit is down -100.25% year-over-year
How far is UPB quarterly operating profit from its all-time high?
UPB quarterly operating profit is currently -303.09% below its historical high of -$9.39M set on September 30, 2023
How does UPB quarterly operating profit rank versus sector peers?
UPB quarterly operating profit is higher than 12.50% of companies in Healthcare sector
When is UPB next earnings release?
The next earnings release for UPB is on
TTM Operating Profit
-$140.51M$18.94M-15.58%
Summary
- Current Value
- As of today, UPB TTM operating profit is -$140.51M, down -15.58% on
- Historical Performance
- UPB TTM operating profit is down -113.62% year-over-year, and down -1397.04% over the past 3 years
- All-Time High Comparison
- UPB TTM operating profit is currently -1397.04% below its historical high of -$9.39M set on
- 3-Year Low Comparison
- UPB TTM operating profit is at its 3-year low
- Sector Comparison
- UPB TTM operating profit is higher than 12.68% of companies in Healthcare sector
Performance
| Metric | Date | Value | 3M | 1Y | 3Y | 5Y |
|---|---|---|---|---|---|---|
| TTM Operating Profit | -$140.51M | -15.6% | -113.6% | -1397.0% | -1397.0% | |
| Annual Operating Profit | -$77.76M | – | -93.9% | -225.3% | -225.3% | |
| Quarterly Operating Profit | -$37.83M | +14.7% | -100.3% | -303.1% | -303.1% | |
| Price | $27.54 | +45.6% | +70.1% | – | – | |
| PE Ratio | - | – | – | – | – | |
| TTM Revenue | $2.80M | +2.8% | +26.8% | +350.7% | +350.7% | |
| TTM EPS | -$2.28 | -11.4% | -56.6% | -1227.1% | -1227.1% | |
| TTM Gross Profit | $2.62M | +2.3% | +341.6% | – | – | |
| Quarterly Operating Expenses | $38.49M | -14.9% | +97.5% | +284.6% | +284.6% |
TTM Operating Profit Highs
| Period | High | Date | Current |
|---|---|---|---|
| 1Y | -$77.76M | N/A | -80.7% |
| 3Y | -$9.39M | -1397.0% | |
| 5Y | -$9.39M | -1397.0% | |
| All | -$9.39M | -1397.0% |
TTM Operating Profit Lows
| Period | Low | Date | Current |
|---|---|---|---|
| 1Y | -$140.51M | at low | |
| 3Y | -$140.51M | at low | |
| 5Y | -$140.51M | at low | |
| All | -$140.51M | at low |
TTM Operating Profit History
| Month | Value | Change |
|---|---|---|
| -$140.51M | -15.6% | |
| -$121.57M | -28.3% | |
| -$94.76M | -21.9% | |
| -$77.76M | -18.2% | |
| -$65.78M | -16.9% |
| Month | Value | Change |
|---|---|---|
| -$56.27M | -45.3% | |
| -$38.73M | -63.3% | |
| -$23.72M | -152.7% | |
| -$9.39M | - |
FAQ
What is the current TTM operating profit of UPB?
As of today, UPB TTM operating profit is -$140.51M
What is UPB TTM operating profit most recent change?
UPB TTM operating profit was down -15.58% on September 30, 2025
What is 1-year change in UPB TTM operating profit?
UPB TTM operating profit is down -113.62% year-over-year
How far is UPB TTM operating profit from its all-time high?
UPB TTM operating profit is currently -1397.04% below its historical high of -$9.39M set on September 30, 2023
How does UPB TTM operating profit rank versus sector peers?
UPB TTM operating profit is higher than 12.68% of companies in Healthcare sector
When is UPB next earnings release?
The next earnings release for UPB is on
Operating Profit Formula
Operating Profit = −
Data Sources & References
- UPB Official Website upstreambio.com
- Most Recent Quarterly Report (10-Q) www.sec.gov/Archives/edgar/data/2022626/000119312525265713/0001193125-25-265713-index.htm
- Most Recent Annual Report (10-K) www.sec.gov/Archives/edgar/data/2022626/000095017025037621/0000950170-25-037621-index.htm
- UPB Profile on Yahoo Finance finance.yahoo.com/quote/UPB
- UPB Profile on NASDAQ.com www.nasdaq.com/market-activity/stocks/upb