Upstream Bio, Inc. (UPB) Gross margin

annual gross margin:

96.24%-1.24%(-1.27%)
December 31, 2024

Summary

  • As of today (September 16, 2025), UPB annual gross profit margin is 96.24%, with the most recent change of -1.24% (-1.27%) on December 31, 2024.
  • During the last 3 years, UPB annual gross margin has fallen by -3.18% (-3.20%).
  • UPB annual gross margin is now -3.20% below its all-time high of 99.42%, reached on December 1, 2022.

Performance

UPB Gross margin Chart

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OtherUPBprofitability metrics

quarterly gross margin:

93.92%+1.52%(+1.65%)
June 30, 2025

Summary

  • As of today (September 16, 2025), UPB quarterly gross profit margin is 93.92%, with the most recent change of +1.52% (+1.65%) on June 30, 2025.
  • UPB quarterly gross margin is now -3.86% below its all-time high of 97.69%, reached on September 30, 2024.

Performance

UPB quarterly gross margin Chart

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Gross margin Formula

Gross Margin =  Gross Profit
Revenue
✕ 100%

UPB Gross margin Trends

PeriodPeriodAnnualAnnualQuarterlyQuarterly
1 y1 year-1.3%-
3 y3 years-3.2%-
5 y5 years-3.2%-

UPB Gross margin Highs & Lows

PeriodPeriodAnnual vs highAnnual vs highAnnual vs lowAnnual vs lowQuarter. vs highQuarter. vs highQuarter. vs lowQuarter. vs low
3 y3-year-3.2%at low-3.9%+2.1%
5 y5-year-3.2%at low-3.9%+2.1%
alltimeall time-3.2%at low-3.9%+2.1%

UPB Gross margin History

DateAnnualQuarterly
Jun 2025
-
93.92%(+1.6%)
Mar 2025
-
92.40%(+0.4%)
Dec 2024
96.24%
92.01%(-5.8%)
DateAnnualQuarterly
Sep 2024
-
97.69%
Dec 2023
97.48%(-2.0%)
-
Dec 2022
99.42%
-

FAQ

  • What is Upstream Bio, Inc. annual gross profit margin?
  • What is the all time high annual gross margin for Upstream Bio, Inc.?
  • What is Upstream Bio, Inc. annual gross margin year-on-year change?
  • What is Upstream Bio, Inc. quarterly gross profit margin?
  • What is the all time high quarterly gross margin for Upstream Bio, Inc.?

What is Upstream Bio, Inc. annual gross profit margin?

The current annual gross margin of UPB is 96.24%

What is the all time high annual gross margin for Upstream Bio, Inc.?

Upstream Bio, Inc. all-time high annual gross profit margin is 99.42%

What is Upstream Bio, Inc. annual gross margin year-on-year change?

Over the past year, UPB annual gross profit margin has changed by -1.24% (-1.27%)

What is Upstream Bio, Inc. quarterly gross profit margin?

The current quarterly gross margin of UPB is 93.92%

What is the all time high quarterly gross margin for Upstream Bio, Inc.?

Upstream Bio, Inc. all-time high quarterly gross profit margin is 97.69%
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