What is the current MACD of IONS?

As of today, IONS MACD is -$1.21

What is the current MACD signal of IONS?

As of today, IONS MACD signal is -$1.70

What is the current MACD histogram of IONS?

As of today, IONS MACD histogram is $0.50

IONS Stock MACD History & Chart Since 1991

MACD

-$1.21$0.18+13.16%

October 28, 2026

Summary

Current Value: As of today, IONS MACD is -$1.21, up +13.16% on October 28, 2026
1-Month High: IONS MACD is currently at its 1-month high
1-Year High: IONS MACD is currently -139.80% below its 1-year high of $3.03 set on December 3, 2025
1-Month Low: IONS MACD is +69.34% above its 1-month low of -$3.93 reached on September 28, 2026
1-Year Low: IONS MACD is +80.91% above its 1-year low of -$6.31 reached on July 22, 2026

MACD Chart

Performance

IONS Performance
Metric	Date	Value	1D	1M	3M	YTD	1Y	3Y	5Y
MACD	Oct 28, 26	-$1.21	+13.2%	+69.3%	+78.1%	-257.4%	-141.2%	-402.3%	+17.7%
MACD Signal	Oct 28, 26	-$1.70	+6.8%	+50.6%	+67.2%	-254.0%	-150.4%	-299.9%	-23.1%
MACD Histogram	Oct 28, 26	$0.50	+13.2%	+203.4%	+265.5%	+246.2%	+209.5%	+209.9%	+724.0%
Price	Oct 28, 26	$44.90	+2.1%	-1.5%	-18.8%	-43.2%	-39.0%	+1.9%	+43.9%
14-Day RSI	Oct 28, 26	48.07	+8.7%	+42.6%	+55.4%	-6.8%	-34.7%	+6.8%	+16.4%
ATR	Oct 28, 26	$1.68	+1.0%	-28.1%	-43.2%	-17.7%	-12.1%	+12.2%	+28.8%
Beta	Oct 28, 26	0.51	-1.9%	+10.9%	+264.3%	-29.2%	-34.6%	-7.3%	-51.0%
10-Day Volatility	Oct 28, 26	37.85%	+2.8%	-41.8%	+42.6%	+66.7%	+61.4%	-9.5%	-52.6%
50-Day SMA	Oct 28, 26	$49.65	-0.6%	-9.2%	-29.8%	-35.2%	-20.1%	+14.1%	+40.4%
20-Day SMA	Oct 28, 26	$43.84	+0.0%	-14.3%	-31.3%	-45.1%	-38.1%	-4.6%	+35.9%
50-Day EMA	Oct 28, 26	$48.70	-0.3%	-12.1%	-28.3%	-35.8%	-22.9%	+10.4%	+41.7%
20-Day EMA	Oct 28, 26	$44.58	+0.1%	-10.2%	-27.3%	-43.8%	-36.5%	-2.2%	+38.6%

MACD Highs

IONS MACD Highs Comparison
Period	High	Date	Current
1M	-$1.21	Oct 28, 26	at high
3M	$0.58	Aug 28, 26	-308.3%
6M	$2.40	Jul 8, 26	-150.2%
1Y	$3.03	Dec 3, 25	-139.8%
3Y	$5.88	Sep 12, 25	-120.5%
5Y	$5.88	Sep 12, 25	-120.5%
All	$5.88	Sep 12, 25	-120.5%

MACD Lows

IONS MACD Lows Comparison
Period	Low	Date	Current
1M	-$3.93	Sep 28, 26	+69.3%
3M	-$5.50	Jul 28, 26	+78.1%
6M	-$6.31	Jul 22, 26	+80.9%
1Y	-$6.31	Jul 22, 26	+80.9%
3Y	-$6.31	Jul 22, 26	+80.9%
5Y	-$6.31	Jul 22, 26	+80.9%
All	-$6.31	Jul 22, 26	+80.9%

MACD History

Date	Value	Change
Oct 28, 2026	-$1.21	-257.4%
Dec 31, 2025	$0.77	+274.1%
Dec 31, 2024	-$0.44	-181.0%
Dec 31, 2023	$0.54	+155.6%
Dec 31, 2022	-$0.98	-1,666.3%
Dec 31, 2021	$0.06	-97.2%
Dec 31, 2020	$2.26	+9,820.2%
Dec 31, 2019	-$0.02	+93.2%
Dec 31, 2018	-$0.34	+66.5%
Dec 31, 2017	-$1.02	-142.8%
Dec 31, 2016	$2.38	+150.7%
Dec 31, 2015	$0.95	-67.4%
Dec 31, 2014	$2.91	+133.2%
Dec 31, 2013	$1.25	+378.4%
Dec 31, 2012	$0.26	+1,510.3%
Dec 31, 2011	-$0.02	-109.3%
Dec 31, 2010	$0.20	+284.5%
Dec 31, 2009	-$0.11	-129.9%

Date	Value	Change
Dec 31, 2008	$0.36	+280.3%
Dec 31, 2007	-$0.20	-174.2%
Dec 31, 2006	$0.27	+374.7%
Dec 31, 2005	$0.06	-75.7%
Dec 31, 2004	$0.23	+2.6%
Dec 31, 2003	$0.23	+140.4%
Dec 31, 2002	-$0.56	-8,732.3%
Dec 31, 2001	$0.01	+110.4%
Dec 31, 2000	-$0.06	+97.1%
Dec 31, 1999	-$2.20	-676.0%
Dec 31, 1998	$0.38	+151.2%
Dec 31, 1997	-$0.75	-392.6%
Dec 31, 1996	$0.25	-55.3%
Dec 31, 1995	$0.57	+587.8%
Dec 31, 1994	-$0.12	-201.0%
Dec 31, 1993	-$0.04	+77.0%
Dec 31, 1992	-$0.17	+70.0%
Dec 31, 1991	-$0.56	-

FAQ

What is the current MACD of IONS?: As of today, IONS MACD is -$1.21

MACD Formula

MACD = EMA(12) − EMA(26)

MACD Signal

-$1.70$0.12+6.82%

October 28, 2026

Summary

Current Value: As of today, IONS MACD signal is -$1.70, up +6.82% on October 28, 2026
1-Month High: IONS MACD signal is currently at its 1-month high
1-Year High: IONS MACD signal is currently -150.44% below its 1-year high of $3.38 set on October 28, 2025
1-Month Low: IONS MACD signal is +51.95% above its 1-month low of -$3.55 reached on October 1, 2026
1-Year Low: IONS MACD signal is +67.63% above its 1-year low of -$5.26 reached on July 31, 2026

Performance

IONS Performance
Metric	Date	Value	1D	1M	3M	YTD	1Y	3Y	5Y
MACD Signal	Oct 28, 26	-$1.70	+6.8%	+50.6%	+67.2%	-254.0%	-150.4%	-299.9%	-23.1%
MACD	Oct 28, 26	-$1.21	+13.2%	+69.3%	+78.1%	-257.4%	-141.2%	-402.3%	+17.7%
MACD Histogram	Oct 28, 26	$0.50	+13.2%	+203.4%	+265.5%	+246.2%	+209.5%	+209.9%	+724.0%
Price	Oct 28, 26	$44.90	+2.1%	-1.5%	-18.8%	-43.2%	-39.0%	+1.9%	+43.9%
14-Day RSI	Oct 28, 26	48.07	+8.7%	+42.6%	+55.4%	-6.8%	-34.7%	+6.8%	+16.4%
ATR	Oct 28, 26	$1.68	+1.0%	-28.1%	-43.2%	-17.7%	-12.1%	+12.2%	+28.8%
Beta	Oct 28, 26	0.51	-1.9%	+10.9%	+264.3%	-29.2%	-34.6%	-7.3%	-51.0%
10-Day Volatility	Oct 28, 26	37.85%	+2.8%	-41.8%	+42.6%	+66.7%	+61.4%	-9.5%	-52.6%
50-Day SMA	Oct 28, 26	$49.65	-0.6%	-9.2%	-29.8%	-35.2%	-20.1%	+14.1%	+40.4%
20-Day SMA	Oct 28, 26	$43.84	+0.0%	-14.3%	-31.3%	-45.1%	-38.1%	-4.6%	+35.9%
50-Day EMA	Oct 28, 26	$48.70	-0.3%	-12.1%	-28.3%	-35.8%	-22.9%	+10.4%	+41.7%
20-Day EMA	Oct 28, 26	$44.58	+0.1%	-10.2%	-27.3%	-43.8%	-36.5%	-2.2%	+38.6%

MACD Signal Highs

IONS MACD Signal Highs Comparison
Period	High	Date	Current
1M	-$1.70	Oct 28, 26	at high
3M	$0.09	Sep 3, 26	-1992.9%
6M	$1.48	Jul 8, 26	-215.5%
1Y	$3.38	Oct 28, 25	-150.4%
3Y	$4.94	Sep 18, 25	-134.5%
5Y	$4.94	Sep 18, 25	-134.5%
All	$4.94	Sep 18, 25	-134.5%

MACD Signal Lows

IONS MACD Signal Lows Comparison
Period	Low	Date	Current
1M	-$3.55	Oct 1, 26	+52.0%
3M	-$5.26	Jul 31, 26	+67.6%
6M	-$5.26	Jul 31, 26	+67.6%
1Y	-$5.26	Jul 31, 26	+67.6%
3Y	-$5.26	Jul 31, 26	+67.6%
5Y	-$5.26	Jul 31, 26	+67.6%
All	-$5.26	Jul 31, 26	+67.6%

MACD Signal History

Date	Value	Change
Oct 28, 2026	-$1.70	-254.0%
Dec 31, 2025	$1.11	+501.9%
Dec 31, 2024	-$0.28	-149.2%
Dec 31, 2023	$0.56	+152.6%
Dec 31, 2022	-$1.07	-1,617.8%
Dec 31, 2021	$0.07	-96.1%
Dec 31, 2020	$1.80	+283.5%
Dec 31, 2019	$0.47	+275.1%
Dec 31, 2018	-$0.27	+70.2%
Dec 31, 2017	-$0.90	-131.6%
Dec 31, 2016	$2.85	+367.4%
Dec 31, 2015	$0.61	-80.0%
Dec 31, 2014	$3.05	+134.0%
Dec 31, 2013	$1.30	+566.0%
Dec 31, 2012	$0.20	+422.6%
Dec 31, 2011	-$0.06	-128.7%
Dec 31, 2010	$0.21	+165.5%
Dec 31, 2009	-$0.32	-373.2%

Date	Value	Change
Dec 31, 2008	$0.12	+188.7%
Dec 31, 2007	-$0.13	-130.4%
Dec 31, 2006	$0.44	+488.3%
Dec 31, 2005	$0.07	-73.3%
Dec 31, 2004	$0.28	+213.1%
Dec 31, 2003	$0.09	+114.3%
Dec 31, 2002	-$0.62	-833.4%
Dec 31, 2001	-$0.07	+68.0%
Dec 31, 2000	-$0.21	+89.4%
Dec 31, 1999	-$1.97	-1,019.9%
Dec 31, 1998	$0.21	+126.8%
Dec 31, 1997	-$0.80	-345.1%
Dec 31, 1996	$0.33	-41.3%
Dec 31, 1995	$0.56	+744.2%
Dec 31, 1994	-$0.09	+27.0%
Dec 31, 1993	-$0.12	-8.8%
Dec 31, 1992	-$0.11	+88.0%
Dec 31, 1991	-$0.90	-

FAQ

What is the current MACD signal of IONS?: As of today, IONS MACD signal is -$1.70

MACD Signal Formula

Signal = EMA(9) of MACD

MACD Histogram

$0.50$0.06+13.16%

October 28, 2026

Summary

Current Value: As of today, IONS MACD histogram is $0.50, up +13.16% on October 28, 2026
1-Month High: IONS MACD histogram is currently -19.14% below its 1-month high of $0.62 set on October 20, 2026
1-Year High: IONS MACD histogram is currently -62.37% below its 1-year high of $1.33 set on August 19, 2026
1-Month Low: IONS MACD histogram is +203.40% above its 1-month low of -$0.48 reached on September 28, 2026
1-Year Low: IONS MACD histogram is +115.92% above its 1-year low of -$3.13 reached on July 15, 2026

Performance

IONS Performance
Metric	Date	Value	1D	1M	3M	YTD	1Y	3Y	5Y
MACD Histogram	Oct 28, 26	$0.50	+13.2%	+203.4%	+265.5%	+246.2%	+209.5%	+209.9%	+724.0%
MACD	Oct 28, 26	-$1.21	+13.2%	+69.3%	+78.1%	-257.4%	-141.2%	-402.3%	+17.7%
MACD Signal	Oct 28, 26	-$1.70	+6.8%	+50.6%	+67.2%	-254.0%	-150.4%	-299.9%	-23.1%
Price	Oct 28, 26	$44.90	+2.1%	-1.5%	-18.8%	-43.2%	-39.0%	+1.9%	+43.9%
14-Day RSI	Oct 28, 26	48.07	+8.7%	+42.6%	+55.4%	-6.8%	-34.7%	+6.8%	+16.4%
ATR	Oct 28, 26	$1.68	+1.0%	-28.1%	-43.2%	-17.7%	-12.1%	+12.2%	+28.8%
Beta	Oct 28, 26	0.51	-1.9%	+10.9%	+264.3%	-29.2%	-34.6%	-7.3%	-51.0%
10-Day Volatility	Oct 28, 26	37.85%	+2.8%	-41.8%	+42.6%	+66.7%	+61.4%	-9.5%	-52.6%
50-Day SMA	Oct 28, 26	$49.65	-0.6%	-9.2%	-29.8%	-35.2%	-20.1%	+14.1%	+40.4%
20-Day SMA	Oct 28, 26	$43.84	+0.0%	-14.3%	-31.3%	-45.1%	-38.1%	-4.6%	+35.9%
50-Day EMA	Oct 28, 26	$48.70	-0.3%	-12.1%	-28.3%	-35.8%	-22.9%	+10.4%	+41.7%
20-Day EMA	Oct 28, 26	$44.58	+0.1%	-10.2%	-27.3%	-43.8%	-36.5%	-2.2%	+38.6%

MACD Histogram Highs

IONS MACD Histogram Highs Comparison
Period	High	Date	Current
1M	$0.62	Oct 20, 26	-19.1%
3M	$1.33	Aug 19, 26	-62.4%
6M	$1.33	Aug 19, 26	-62.4%
1Y	$1.33	Aug 19, 26	-62.4%
3Y	$2.14	Sep 9, 25	-76.7%
5Y	$2.14	Sep 9, 25	-76.7%
All	$2.48	Nov 15, 16	-79.9%

MACD Histogram Lows

IONS MACD Histogram Lows Comparison
Period	Low	Date	Current
1M	-$0.48	Sep 28, 26	+203.4%
3M	-$1.52	Sep 18, 26	+132.7%
6M	-$3.13	Jul 15, 26	+115.9%
1Y	-$3.13	Jul 15, 26	+115.9%
3Y	-$3.13	Jul 15, 26	+115.9%
5Y	-$3.13	Jul 15, 26	+115.9%
All	-$3.13	Jul 15, 26	+115.9%

MACD Histogram History

Date	Value	Change
Oct 28, 2026	$0.50	+246.2%
Dec 31, 2025	-$0.34	-107.4%
Dec 31, 2024	-$0.16	-861.4%
Dec 31, 2023	-$0.02	-119.1%
Dec 31, 2022	$0.09	+1,235.4%
Dec 31, 2021	-$0.01	-101.7%
Dec 31, 2020	$0.46	+193.3%
Dec 31, 2019	-$0.49	-581.0%
Dec 31, 2018	-$0.07	+37.7%
Dec 31, 2017	-$0.12	+75.5%
Dec 31, 2016	-$0.47	-240.1%
Dec 31, 2015	$0.34	+341.2%
Dec 31, 2014	-$0.14	-151.6%
Dec 31, 2013	-$0.06	-185.7%
Dec 31, 2012	$0.07	+54.3%
Dec 31, 2011	$0.04	+417.3%
Dec 31, 2010	-$0.01	-106.2%
Dec 31, 2009	$0.22	-10.9%

Date	Value	Change
Dec 31, 2008	$0.24	+463.9%
Dec 31, 2007	-$0.07	+60.8%
Dec 31, 2006	-$0.17	-847.5%
Dec 31, 2005	-$0.02	+61.3%
Dec 31, 2004	-$0.05	-133.6%
Dec 31, 2003	$0.14	+120.5%
Dec 31, 2002	$0.06	-14.9%
Dec 31, 2001	$0.07	-49.8%
Dec 31, 2000	$0.15	+163.2%
Dec 31, 1999	-$0.23	-237.8%
Dec 31, 1998	$0.17	+214.2%
Dec 31, 1997	$0.05	+175.0%
Dec 31, 1996	-$0.07	-594.4%
Dec 31, 1995	$0.01	+147.1%
Dec 31, 1994	-$0.03	-138.6%
Dec 31, 1993	$0.08	+231.9%
Dec 31, 1992	-$0.06	-117.6%
Dec 31, 1991	$0.34	-

FAQ

What is the current MACD histogram of IONS?: As of today, IONS MACD histogram is $0.50

MACD Histogram Formula

Histogram = MACD − Signal

Data Sources & References

IONS Official Website www.ionis.com
Most Recent Annual Report (10-K) www.sec.gov/Archives/edgar/data/874015/000087401526000115/0000874015-26-000115-index.htm
IONS Profile on Yahoo Finance finance.yahoo.com/quote/IONS
IONS Profile on NASDAQ.com www.nasdaq.com/market-activity/stocks/ions