What is the current MACD of IONS?

As of today, IONS MACD is -$5.99

What is the current MACD signal of IONS?

As of today, IONS MACD signal is -$3.35

What is the current MACD histogram of IONS?

As of today, IONS MACD histogram is -$2.64

IONS Stock MACD History & Chart Since 1991

MACD

-$5.99$0.45-8.09%

July 20, 2026

Summary

Current Value: As of today, IONS MACD is -$5.99, down -8.09% on July 20, 2026
1-Month High: IONS MACD is currently -349.34% below its 1-month high of $2.40 set on July 8, 2026
1-Year High: IONS MACD is currently -201.89% below its 1-year high of $5.88 set on September 12, 2025
1-Month Low: IONS MACD is at its 1-month low
1-Year Low: IONS MACD is at its 1-year low

MACD Chart

Performance

IONS Performance
Metric	Date	Value	1D	1M	3M	YTD	1Y	3Y	5Y
MACD	Jul 20, 26	-$5.99	-8.1%	-1512.1%	-10000.0%	-882.6%	-501.6%	-2104.8%	-1119.0%
MACD Signal	Jul 20, 26	-$3.35	-24.6%	-946.7%	-1273.9%	-402.7%	-290.1%	-792.3%	-1235.5%
MACD Histogram	Jul 20, 26	-$2.64	+7.4%	-5018.0%	-1242.8%	-674.5%	-877.8%	-1327.5%	-997.6%
Price	Jul 20, 26	$52.95	-2.6%	-28.6%	-29.2%	-33.1%	+27.4%	+30.3%	+44.2%
14-Day RSI	Jul 20, 26	22.76	-4.7%	-53.0%	-52.9%	-55.9%	-60.9%	-49.2%	-49.7%
ATR	Jul 20, 26	$3.21	-2.9%	+51.1%	+41.8%	+56.9%	+140.8%	+188.2%	+144.6%
Beta	Jul 20, 26	0.17	+6.3%	-59.5%	-67.9%	-76.4%	-80.0%	-75.7%	-81.1%
10-Day Volatility	Jul 20, 26	122.24%	-2.7%	+537.7%	+415.4%	+438.3%	+325.0%	+680.6%	+216.9%
50-Day SMA	Jul 20, 26	$73.18	-0.7%	-2.3%	-4.6%	-4.5%	+96.9%	+80.4%	+96.7%
20-Day SMA	Jul 20, 26	$70.69	-1.5%	-5.3%	-5.1%	-11.5%	+71.2%	+70.9%	+86.1%
50-Day EMA	Jul 20, 26	$71.33	-1.0%	-4.7%	-6.1%	-6.0%	+87.8%	+76.2%	+85.6%
20-Day EMA	Jul 20, 26	$66.26	-2.1%	-10.8%	-11.7%	-16.4%	+62.1%	+59.7%	+77.6%

MACD Highs

IONS MACD Highs Comparison
Period	High	Date	Current
1M	$2.40	Jul 8, 26	-349.3%
3M	$2.40	Jul 8, 26	-349.3%
6M	$2.40	Jul 8, 26	-349.3%
1Y	$5.88	Sep 12, 25	-201.9%
3Y	$5.88	Sep 12, 25	-201.9%
5Y	$5.88	Sep 12, 25	-201.9%
All	$5.88	Sep 12, 25	-201.9%

MACD Lows

IONS MACD Lows Comparison
Period	Low	Date	Current
1M	-$5.99	Jul 20, 26	at low
3M	-$5.99	Jul 20, 26	at low
6M	-$5.99	Jul 20, 26	at low
1Y	-$5.99	Jul 20, 26	at low
3Y	-$5.99	Jul 20, 26	at low
5Y	-$5.99	Jul 20, 26	at low
All	-$5.99	Jul 20, 26	at low

MACD History

Date	Value	Change
Jul 21, 2026	-$5.99	-882.6%
Dec 31, 2025	$0.77	+274.1%
Dec 31, 2024	-$0.44	-181.0%
Dec 31, 2023	$0.54	+155.6%
Dec 31, 2022	-$0.98	-1,666.3%
Dec 31, 2021	$0.06	-97.2%
Dec 31, 2020	$2.26	+9,820.2%
Dec 31, 2019	-$0.02	+93.2%
Dec 31, 2018	-$0.34	+66.5%
Dec 31, 2017	-$1.02	-142.8%
Dec 31, 2016	$2.38	+150.7%
Dec 31, 2015	$0.95	-67.4%
Dec 31, 2014	$2.91	+133.2%
Dec 31, 2013	$1.25	+378.4%
Dec 31, 2012	$0.26	+1,510.3%
Dec 31, 2011	-$0.02	-109.3%
Dec 31, 2010	$0.20	+284.5%
Dec 31, 2009	-$0.11	-129.9%

Date	Value	Change
Dec 31, 2008	$0.36	+280.3%
Dec 31, 2007	-$0.20	-174.2%
Dec 31, 2006	$0.27	+374.7%
Dec 31, 2005	$0.06	-75.7%
Dec 31, 2004	$0.23	+2.6%
Dec 31, 2003	$0.23	+140.4%
Dec 31, 2002	-$0.56	-8,732.3%
Dec 31, 2001	$0.01	+110.4%
Dec 31, 2000	-$0.06	+97.1%
Dec 31, 1999	-$2.20	-676.0%
Dec 31, 1998	$0.38	+151.2%
Dec 31, 1997	-$0.75	-392.6%
Dec 31, 1996	$0.25	-55.3%
Dec 31, 1995	$0.57	+587.8%
Dec 31, 1994	-$0.12	-201.0%
Dec 31, 1993	-$0.04	+77.0%
Dec 31, 1992	-$0.17	+70.0%
Dec 31, 1991	-$0.56	-

FAQ

What is the current MACD of IONS?
As of today, IONS MACD is -$5.99

MACD Formula

MACD = EMA(12) − EMA(26)

MACD Signal

-$3.35$0.66-24.55%

July 20, 2026

Summary

Current Value: As of today, IONS MACD signal is -$3.35, down -24.55% on July 20, 2026
1-Month High: IONS MACD signal is currently -327.04% below its 1-month high of $1.48 set on July 8, 2026
1-Year High: IONS MACD signal is currently -167.79% below its 1-year high of $4.94 set on September 18, 2025
1-Month Low: IONS MACD signal is at its 1-month low
1-Year Low: IONS MACD signal is at its 1-year low

Performance

IONS Performance
Metric	Date	Value	1D	1M	3M	YTD	1Y	3Y	5Y
MACD Signal	Jul 20, 26	-$3.35	-24.6%	-946.7%	-1273.9%	-402.7%	-290.1%	-792.3%	-1235.5%
MACD	Jul 20, 26	-$5.99	-8.1%	-1512.1%	-10000.0%	-882.6%	-501.6%	-2104.8%	-1119.0%
MACD Histogram	Jul 20, 26	-$2.64	+7.4%	-5018.0%	-1242.8%	-674.5%	-877.8%	-1327.5%	-997.6%
Price	Jul 20, 26	$52.95	-2.6%	-28.6%	-29.2%	-33.1%	+27.4%	+30.3%	+44.2%
14-Day RSI	Jul 20, 26	22.76	-4.7%	-53.0%	-52.9%	-55.9%	-60.9%	-49.2%	-49.7%
ATR	Jul 20, 26	$3.21	-2.9%	+51.1%	+41.8%	+56.9%	+140.8%	+188.2%	+144.6%
Beta	Jul 20, 26	0.17	+6.3%	-59.5%	-67.9%	-76.4%	-80.0%	-75.7%	-81.1%
10-Day Volatility	Jul 20, 26	122.24%	-2.7%	+537.7%	+415.4%	+438.3%	+325.0%	+680.6%	+216.9%
50-Day SMA	Jul 20, 26	$73.18	-0.7%	-2.3%	-4.6%	-4.5%	+96.9%	+80.4%	+96.7%
20-Day SMA	Jul 20, 26	$70.69	-1.5%	-5.3%	-5.1%	-11.5%	+71.2%	+70.9%	+86.1%
50-Day EMA	Jul 20, 26	$71.33	-1.0%	-4.7%	-6.1%	-6.0%	+87.8%	+76.2%	+85.6%
20-Day EMA	Jul 20, 26	$66.26	-2.1%	-10.8%	-11.7%	-16.4%	+62.1%	+59.7%	+77.6%

MACD Signal Highs

IONS MACD Signal Highs Comparison
Period	High	Date	Current
1M	$1.48	Jul 8, 26	-327.0%
3M	$1.48	Jul 8, 26	-327.0%
6M	$1.48	Jul 8, 26	-327.0%
1Y	$4.94	Sep 18, 25	-167.8%
3Y	$4.94	Sep 18, 25	-167.8%
5Y	$4.94	Sep 18, 25	-167.8%
All	$4.94	Sep 18, 25	-167.8%

MACD Signal Lows

IONS MACD Signal Lows Comparison
Period	Low	Date	Current
1M	-$3.35	Jul 20, 26	at low
3M	-$3.35	Jul 20, 26	at low
6M	-$3.35	Jul 20, 26	at low
1Y	-$3.35	Jul 20, 26	at low
3Y	-$3.35	Jul 20, 26	at low
5Y	-$3.35	Jul 20, 26	at low
All	-$4.89	Feb 11, 16	+31.4%

MACD Signal History

Date	Value	Change
Jul 21, 2026	-$3.35	-402.7%
Dec 31, 2025	$1.11	+501.9%
Dec 31, 2024	-$0.28	-149.2%
Dec 31, 2023	$0.56	+152.6%
Dec 31, 2022	-$1.07	-1,617.8%
Dec 31, 2021	$0.07	-96.1%
Dec 31, 2020	$1.80	+283.5%
Dec 31, 2019	$0.47	+275.1%
Dec 31, 2018	-$0.27	+70.2%
Dec 31, 2017	-$0.90	-131.6%
Dec 31, 2016	$2.85	+367.4%
Dec 31, 2015	$0.61	-80.0%
Dec 31, 2014	$3.05	+134.0%
Dec 31, 2013	$1.30	+566.0%
Dec 31, 2012	$0.20	+422.6%
Dec 31, 2011	-$0.06	-128.7%
Dec 31, 2010	$0.21	+165.5%
Dec 31, 2009	-$0.32	-373.2%

Date	Value	Change
Dec 31, 2008	$0.12	+188.7%
Dec 31, 2007	-$0.13	-130.4%
Dec 31, 2006	$0.44	+488.3%
Dec 31, 2005	$0.07	-73.3%
Dec 31, 2004	$0.28	+213.1%
Dec 31, 2003	$0.09	+114.3%
Dec 31, 2002	-$0.62	-833.4%
Dec 31, 2001	-$0.07	+68.0%
Dec 31, 2000	-$0.21	+89.4%
Dec 31, 1999	-$1.97	-1,019.9%
Dec 31, 1998	$0.21	+126.8%
Dec 31, 1997	-$0.80	-345.1%
Dec 31, 1996	$0.33	-41.3%
Dec 31, 1995	$0.56	+744.2%
Dec 31, 1994	-$0.09	+27.0%
Dec 31, 1993	-$0.12	-8.8%
Dec 31, 1992	-$0.11	+88.0%
Dec 31, 1991	-$0.90	-

FAQ

What is the current MACD signal of IONS?
As of today, IONS MACD signal is -$3.35

MACD Signal Formula

Signal = EMA(9) of MACD

MACD Histogram

-$2.64$0.21+7.42%

July 20, 2026

Summary

Current Value: As of today, IONS MACD histogram is -$2.64, up +7.42% on July 20, 2026
1-Month High: IONS MACD histogram is currently -369.53% below its 1-month high of $0.98 set on July 7, 2026
1-Year High: IONS MACD histogram is currently -223.54% below its 1-year high of $2.14 set on September 9, 2025
1-Month Low: IONS MACD histogram is +15.65% above its 1-month low of -$3.13 reached on July 15, 2026
1-Year Low: IONS MACD histogram is +15.65% above its 1-year low of -$3.13 reached on July 15, 2026

Performance

IONS Performance
Metric	Date	Value	1D	1M	3M	YTD	1Y	3Y	5Y
MACD Histogram	Jul 20, 26	-$2.64	+7.4%	-5018.0%	-1242.8%	-674.5%	-877.8%	-1327.5%	-997.6%
MACD	Jul 20, 26	-$5.99	-8.1%	-1512.1%	-10000.0%	-882.6%	-501.6%	-2104.8%	-1119.0%
MACD Signal	Jul 20, 26	-$3.35	-24.6%	-946.7%	-1273.9%	-402.7%	-290.1%	-792.3%	-1235.5%
Price	Jul 20, 26	$52.95	-2.6%	-28.6%	-29.2%	-33.1%	+27.4%	+30.3%	+44.2%
14-Day RSI	Jul 20, 26	22.76	-4.7%	-53.0%	-52.9%	-55.9%	-60.9%	-49.2%	-49.7%
ATR	Jul 20, 26	$3.21	-2.9%	+51.1%	+41.8%	+56.9%	+140.8%	+188.2%	+144.6%
Beta	Jul 20, 26	0.17	+6.3%	-59.5%	-67.9%	-76.4%	-80.0%	-75.7%	-81.1%
10-Day Volatility	Jul 20, 26	122.24%	-2.7%	+537.7%	+415.4%	+438.3%	+325.0%	+680.6%	+216.9%
50-Day SMA	Jul 20, 26	$73.18	-0.7%	-2.3%	-4.6%	-4.5%	+96.9%	+80.4%	+96.7%
20-Day SMA	Jul 20, 26	$70.69	-1.5%	-5.3%	-5.1%	-11.5%	+71.2%	+70.9%	+86.1%
50-Day EMA	Jul 20, 26	$71.33	-1.0%	-4.7%	-6.1%	-6.0%	+87.8%	+76.2%	+85.6%
20-Day EMA	Jul 20, 26	$66.26	-2.1%	-10.8%	-11.7%	-16.4%	+62.1%	+59.7%	+77.6%

MACD Histogram Highs

IONS MACD Histogram Highs Comparison
Period	High	Date	Current
1M	$0.98	Jul 7, 26	-369.5%
3M	$0.98	Jul 7, 26	-369.5%
6M	$0.98	Jul 7, 26	-369.5%
1Y	$2.14	Sep 9, 25	-223.5%
3Y	$2.14	Sep 9, 25	-223.5%
5Y	$2.14	Sep 9, 25	-223.5%
All	$2.48	Nov 15, 16	-206.4%

MACD Histogram Lows

IONS MACD Histogram Lows Comparison
Period	Low	Date	Current
1M	-$3.13	Jul 15, 26	+15.7%
3M	-$3.13	Jul 15, 26	+15.7%
6M	-$3.13	Jul 15, 26	+15.7%
1Y	-$3.13	Jul 15, 26	+15.7%
3Y	-$3.13	Jul 15, 26	+15.7%
5Y	-$3.13	Jul 15, 26	+15.7%
All	-$3.13	Jul 15, 26	+15.7%

MACD Histogram History

Date	Value	Change
Jul 21, 2026	-$2.64	-674.5%
Dec 31, 2025	-$0.34	-107.4%
Dec 31, 2024	-$0.16	-861.4%
Dec 31, 2023	-$0.02	-119.1%
Dec 31, 2022	$0.09	+1,235.4%
Dec 31, 2021	-$0.01	-101.7%
Dec 31, 2020	$0.46	+193.3%
Dec 31, 2019	-$0.49	-581.0%
Dec 31, 2018	-$0.07	+37.7%
Dec 31, 2017	-$0.12	+75.5%
Dec 31, 2016	-$0.47	-240.1%
Dec 31, 2015	$0.34	+341.2%
Dec 31, 2014	-$0.14	-151.6%
Dec 31, 2013	-$0.06	-185.7%
Dec 31, 2012	$0.07	+54.3%
Dec 31, 2011	$0.04	+417.3%
Dec 31, 2010	-$0.01	-106.2%
Dec 31, 2009	$0.22	-10.9%

Date	Value	Change
Dec 31, 2008	$0.24	+463.9%
Dec 31, 2007	-$0.07	+60.8%
Dec 31, 2006	-$0.17	-847.5%
Dec 31, 2005	-$0.02	+61.3%
Dec 31, 2004	-$0.05	-133.6%
Dec 31, 2003	$0.14	+120.5%
Dec 31, 2002	$0.06	-14.9%
Dec 31, 2001	$0.07	-49.8%
Dec 31, 2000	$0.15	+163.2%
Dec 31, 1999	-$0.23	-237.8%
Dec 31, 1998	$0.17	+214.2%
Dec 31, 1997	$0.05	+175.0%
Dec 31, 1996	-$0.07	-594.4%
Dec 31, 1995	$0.01	+147.1%
Dec 31, 1994	-$0.03	-138.6%
Dec 31, 1993	$0.08	+231.9%
Dec 31, 1992	-$0.06	-117.6%
Dec 31, 1991	$0.34	-

FAQ

What is the current MACD histogram of IONS?
As of today, IONS MACD histogram is -$2.64

MACD Histogram Formula

Histogram = MACD − Signal

Data Sources & References

IONS Official Website www.ionis.com
Most Recent Annual Report (10-K) www.sec.gov/Archives/edgar/data/874015/000087401526000115/0000874015-26-000115-index.htm
IONS Profile on Yahoo Finance finance.yahoo.com/quote/IONS
IONS Profile on NASDAQ.com www.nasdaq.com/market-activity/stocks/ions