What is the current MACD of IONS?

As of today, IONS MACD is -$2.80

What is the current MACD signal of IONS?

As of today, IONS MACD signal is -$3.24

What is the current MACD histogram of IONS?

As of today, IONS MACD histogram is $0.44

IONS Stock MACD History & Chart Since 1991

MACD

-$2.80$0.27+8.68%

October 9, 2026

Summary

Current Value: As of today, IONS MACD is -$2.80, up +8.68% on October 9, 2026
1-Month High: IONS MACD is currently -546.68% below its 1-month high of -$0.43 set on September 9, 2026
1-Year High: IONS MACD is currently -166.95% below its 1-year high of $4.18 set on October 9, 2025
1-Month Low: IONS MACD is +31.83% above its 1-month low of -$4.10 reached on September 24, 2026
1-Year Low: IONS MACD is +55.67% above its 1-year low of -$6.31 reached on July 22, 2026

MACD Chart

Performance

IONS Performance
Metric	Date	Value	1D	1M	3M	YTD	1Y	3Y	5Y
MACD	Oct 9, 26	-$2.80	+8.7%	-546.7%	-409.2%	-465.6%	-166.9%	-327.5%	-137.1%
MACD Signal	Oct 9, 26	-$3.24	+3.3%	-5324.3%	-337.9%	-392.7%	-177.3%	-395.2%	-194.2%
MACD Histogram	Oct 9, 26	$0.44	+54.9%	+218.0%	+196.5%	+229.1%	+3649.2%	+231.2%	+655.0%
Price	Oct 9, 26	$45.28	+4.6%	-19.2%	-29.6%	-42.8%	-35.6%	-2.5%	+32.8%
14-Day RSI	Oct 9, 26	40.57	+29.3%	+2.2%	+30.3%	-21.4%	-50.0%	-36.1%	-0.9%
ATR	Oct 9, 26	$1.93	+2.7%	-13.7%	-49.0%	-5.6%	+2.2%	+33.9%	+73.2%
Beta	Oct 9, 26	0.47	+2.2%	+27.0%	+135.0%	-34.7%	-42.0%	+6.8%	-52.0%
10-Day Volatility	Oct 9, 26	34.52%	+32.1%	+12.0%	-73.5%	+52.0%	+72.0%	-46.1%	+1.4%
50-Day SMA	Oct 9, 26	$52.81	-0.3%	-12.3%	-30.4%	-31.1%	-3.0%	+26.5%	+41.8%
20-Day SMA	Oct 9, 26	$45.08	-1.0%	-24.3%	-41.6%	-43.5%	-30.4%	+1.9%	+28.3%
50-Day EMA	Oct 9, 26	$52.02	-0.5%	-15.2%	-32.1%	-31.4%	-8.8%	+22.3%	+42.6%
20-Day EMA	Oct 9, 26	$46.43	-0.3%	-21.4%	-40.3%	-41.4%	-28.3%	+5.0%	+32.9%

MACD Highs

IONS MACD Highs Comparison
Period	High	Date	Current
1M	-$0.43	Sep 9, 26	-546.7%
3M	$0.91	Jul 9, 26	-409.2%
6M	$2.40	Jul 8, 26	-216.5%
1Y	$4.18	Oct 9, 25	-166.9%
3Y	$5.88	Sep 12, 25	-147.6%
5Y	$5.88	Sep 12, 25	-147.6%
All	$5.88	Sep 12, 25	-147.6%

MACD Lows

IONS MACD Lows Comparison
Period	Low	Date	Current
1M	-$4.10	Sep 24, 26	+31.8%
3M	-$6.31	Jul 22, 26	+55.7%
6M	-$6.31	Jul 22, 26	+55.7%
1Y	-$6.31	Jul 22, 26	+55.7%
3Y	-$6.31	Jul 22, 26	+55.7%
5Y	-$6.31	Jul 22, 26	+55.7%
All	-$6.31	Jul 22, 26	+55.7%

MACD History

Date	Value	Change
Oct 9, 2026	-$2.80	-465.6%
Dec 31, 2025	$0.77	+274.1%
Dec 31, 2024	-$0.44	-181.0%
Dec 31, 2023	$0.54	+155.6%
Dec 31, 2022	-$0.98	-1,666.3%
Dec 31, 2021	$0.06	-97.2%
Dec 31, 2020	$2.26	+9,820.2%
Dec 31, 2019	-$0.02	+93.2%
Dec 31, 2018	-$0.34	+66.5%
Dec 31, 2017	-$1.02	-142.8%
Dec 31, 2016	$2.38	+150.7%
Dec 31, 2015	$0.95	-67.4%
Dec 31, 2014	$2.91	+133.2%
Dec 31, 2013	$1.25	+378.4%
Dec 31, 2012	$0.26	+1,510.3%
Dec 31, 2011	-$0.02	-109.3%
Dec 31, 2010	$0.20	+284.5%
Dec 31, 2009	-$0.11	-129.9%

Date	Value	Change
Dec 31, 2008	$0.36	+280.3%
Dec 31, 2007	-$0.20	-174.2%
Dec 31, 2006	$0.27	+374.7%
Dec 31, 2005	$0.06	-75.7%
Dec 31, 2004	$0.23	+2.6%
Dec 31, 2003	$0.23	+140.4%
Dec 31, 2002	-$0.56	-8,732.3%
Dec 31, 2001	$0.01	+110.4%
Dec 31, 2000	-$0.06	+97.1%
Dec 31, 1999	-$2.20	-676.0%
Dec 31, 1998	$0.38	+151.2%
Dec 31, 1997	-$0.75	-392.6%
Dec 31, 1996	$0.25	-55.3%
Dec 31, 1995	$0.57	+587.8%
Dec 31, 1994	-$0.12	-201.0%
Dec 31, 1993	-$0.04	+77.0%
Dec 31, 1992	-$0.17	+70.0%
Dec 31, 1991	-$0.56	-

FAQ

What is the current MACD of IONS?: As of today, IONS MACD is -$2.80

MACD Formula

MACD = EMA(12) − EMA(26)

MACD Signal

-$3.24$0.11+3.29%

October 9, 2026

Summary

Current Value: As of today, IONS MACD signal is -$3.24, up +3.29% on October 9, 2026
1-Month High: IONS MACD signal is currently -5324.29% below its 1-month high of -$0.06 set on September 9, 2026
1-Year High: IONS MACD signal is currently -177.25% below its 1-year high of $4.19 set on October 9, 2025
1-Month Low: IONS MACD signal is +8.67% above its 1-month low of -$3.55 reached on October 1, 2026
1-Year Low: IONS MACD signal is +38.46% above its 1-year low of -$5.26 reached on July 31, 2026

Performance

IONS Performance
Metric	Date	Value	1D	1M	3M	YTD	1Y	3Y	5Y
MACD Signal	Oct 9, 26	-$3.24	+3.3%	-5324.3%	-337.9%	-392.7%	-177.3%	-395.2%	-194.2%
MACD	Oct 9, 26	-$2.80	+8.7%	-546.7%	-409.2%	-465.6%	-166.9%	-327.5%	-137.1%
MACD Histogram	Oct 9, 26	$0.44	+54.9%	+218.0%	+196.5%	+229.1%	+3649.2%	+231.2%	+655.0%
Price	Oct 9, 26	$45.28	+4.6%	-19.2%	-29.6%	-42.8%	-35.6%	-2.5%	+32.8%
14-Day RSI	Oct 9, 26	40.57	+29.3%	+2.2%	+30.3%	-21.4%	-50.0%	-36.1%	-0.9%
ATR	Oct 9, 26	$1.93	+2.7%	-13.7%	-49.0%	-5.6%	+2.2%	+33.9%	+73.2%
Beta	Oct 9, 26	0.47	+2.2%	+27.0%	+135.0%	-34.7%	-42.0%	+6.8%	-52.0%
10-Day Volatility	Oct 9, 26	34.52%	+32.1%	+12.0%	-73.5%	+52.0%	+72.0%	-46.1%	+1.4%
50-Day SMA	Oct 9, 26	$52.81	-0.3%	-12.3%	-30.4%	-31.1%	-3.0%	+26.5%	+41.8%
20-Day SMA	Oct 9, 26	$45.08	-1.0%	-24.3%	-41.6%	-43.5%	-30.4%	+1.9%	+28.3%
50-Day EMA	Oct 9, 26	$52.02	-0.5%	-15.2%	-32.1%	-31.4%	-8.8%	+22.3%	+42.6%
20-Day EMA	Oct 9, 26	$46.43	-0.3%	-21.4%	-40.3%	-41.4%	-28.3%	+5.0%	+32.9%

MACD Signal Highs

IONS MACD Signal Highs Comparison
Period	High	Date	Current
1M	-$0.06	Sep 9, 26	-5324.3%
3M	$1.36	Jul 9, 26	-337.9%
6M	$1.48	Jul 8, 26	-319.5%
1Y	$4.19	Oct 9, 25	-177.3%
3Y	$4.94	Sep 18, 25	-165.5%
5Y	$4.94	Sep 18, 25	-165.5%
All	$4.94	Sep 18, 25	-165.5%

MACD Signal Lows

IONS MACD Signal Lows Comparison
Period	Low	Date	Current
1M	-$3.55	Oct 1, 26	+8.7%
3M	-$5.26	Jul 31, 26	+38.5%
6M	-$5.26	Jul 31, 26	+38.5%
1Y	-$5.26	Jul 31, 26	+38.5%
3Y	-$5.26	Jul 31, 26	+38.5%
5Y	-$5.26	Jul 31, 26	+38.5%
All	-$5.26	Jul 31, 26	+38.5%

MACD Signal History

Date	Value	Change
Oct 9, 2026	-$3.24	-392.7%
Dec 31, 2025	$1.11	+501.9%
Dec 31, 2024	-$0.28	-149.2%
Dec 31, 2023	$0.56	+152.6%
Dec 31, 2022	-$1.07	-1,617.8%
Dec 31, 2021	$0.07	-96.1%
Dec 31, 2020	$1.80	+283.5%
Dec 31, 2019	$0.47	+275.1%
Dec 31, 2018	-$0.27	+70.2%
Dec 31, 2017	-$0.90	-131.6%
Dec 31, 2016	$2.85	+367.4%
Dec 31, 2015	$0.61	-80.0%
Dec 31, 2014	$3.05	+134.0%
Dec 31, 2013	$1.30	+566.0%
Dec 31, 2012	$0.20	+422.6%
Dec 31, 2011	-$0.06	-128.7%
Dec 31, 2010	$0.21	+165.5%
Dec 31, 2009	-$0.32	-373.2%

Date	Value	Change
Dec 31, 2008	$0.12	+188.7%
Dec 31, 2007	-$0.13	-130.4%
Dec 31, 2006	$0.44	+488.3%
Dec 31, 2005	$0.07	-73.3%
Dec 31, 2004	$0.28	+213.1%
Dec 31, 2003	$0.09	+114.3%
Dec 31, 2002	-$0.62	-833.4%
Dec 31, 2001	-$0.07	+68.0%
Dec 31, 2000	-$0.21	+89.4%
Dec 31, 1999	-$1.97	-1,019.9%
Dec 31, 1998	$0.21	+126.8%
Dec 31, 1997	-$0.80	-345.1%
Dec 31, 1996	$0.33	-41.3%
Dec 31, 1995	$0.56	+744.2%
Dec 31, 1994	-$0.09	+27.0%
Dec 31, 1993	-$0.12	-8.8%
Dec 31, 1992	-$0.11	+88.0%
Dec 31, 1991	-$0.90	-

FAQ

What is the current MACD signal of IONS?: As of today, IONS MACD signal is -$3.24

MACD Signal Formula

Signal = EMA(9) of MACD

MACD Histogram

$0.44$0.16+54.86%

October 9, 2026

Summary

Current Value: As of today, IONS MACD histogram is $0.44, up +54.86% on October 9, 2026
1-Month High: IONS MACD histogram is currently at its 1-month high
1-Year High: IONS MACD histogram is currently -66.78% below its 1-year high of $1.33 set on August 19, 2026
1-Month Low: IONS MACD histogram is +128.87% above its 1-month low of -$1.52 reached on September 18, 2026
1-Year Low: IONS MACD histogram is +114.06% above its 1-year low of -$3.13 reached on July 15, 2026

Performance

IONS Performance
Metric	Date	Value	1D	1M	3M	YTD	1Y	3Y	5Y
MACD Histogram	Oct 9, 26	$0.44	+54.9%	+218.0%	+196.5%	+229.1%	+3649.2%	+231.2%	+655.0%
MACD	Oct 9, 26	-$2.80	+8.7%	-546.7%	-409.2%	-465.6%	-166.9%	-327.5%	-137.1%
MACD Signal	Oct 9, 26	-$3.24	+3.3%	-5324.3%	-337.9%	-392.7%	-177.3%	-395.2%	-194.2%
Price	Oct 9, 26	$45.28	+4.6%	-19.2%	-29.6%	-42.8%	-35.6%	-2.5%	+32.8%
14-Day RSI	Oct 9, 26	40.57	+29.3%	+2.2%	+30.3%	-21.4%	-50.0%	-36.1%	-0.9%
ATR	Oct 9, 26	$1.93	+2.7%	-13.7%	-49.0%	-5.6%	+2.2%	+33.9%	+73.2%
Beta	Oct 9, 26	0.47	+2.2%	+27.0%	+135.0%	-34.7%	-42.0%	+6.8%	-52.0%
10-Day Volatility	Oct 9, 26	34.52%	+32.1%	+12.0%	-73.5%	+52.0%	+72.0%	-46.1%	+1.4%
50-Day SMA	Oct 9, 26	$52.81	-0.3%	-12.3%	-30.4%	-31.1%	-3.0%	+26.5%	+41.8%
20-Day SMA	Oct 9, 26	$45.08	-1.0%	-24.3%	-41.6%	-43.5%	-30.4%	+1.9%	+28.3%
50-Day EMA	Oct 9, 26	$52.02	-0.5%	-15.2%	-32.1%	-31.4%	-8.8%	+22.3%	+42.6%
20-Day EMA	Oct 9, 26	$46.43	-0.3%	-21.4%	-40.3%	-41.4%	-28.3%	+5.0%	+32.9%

MACD Histogram Highs

IONS MACD Histogram Highs Comparison
Period	High	Date	Current
1M	$0.44	Oct 9, 26	at high
3M	$1.33	Aug 19, 26	-66.8%
6M	$1.33	Aug 19, 26	-66.8%
1Y	$1.33	Aug 19, 26	-66.8%
3Y	$2.14	Sep 9, 25	-79.4%
5Y	$2.14	Sep 9, 25	-79.4%
All	$2.48	Nov 15, 16	-82.3%

MACD Histogram Lows

IONS MACD Histogram Lows Comparison
Period	Low	Date	Current
1M	-$1.52	Sep 18, 26	+128.9%
3M	-$3.13	Jul 15, 26	+114.1%
6M	-$3.13	Jul 15, 26	+114.1%
1Y	-$3.13	Jul 15, 26	+114.1%
3Y	-$3.13	Jul 15, 26	+114.1%
5Y	-$3.13	Jul 15, 26	+114.1%
All	-$3.13	Jul 15, 26	+114.1%

MACD Histogram History

Date	Value	Change
Oct 9, 2026	$0.44	+229.1%
Dec 31, 2025	-$0.34	-107.4%
Dec 31, 2024	-$0.16	-861.4%
Dec 31, 2023	-$0.02	-119.1%
Dec 31, 2022	$0.09	+1,235.4%
Dec 31, 2021	-$0.01	-101.7%
Dec 31, 2020	$0.46	+193.3%
Dec 31, 2019	-$0.49	-581.0%
Dec 31, 2018	-$0.07	+37.7%
Dec 31, 2017	-$0.12	+75.5%
Dec 31, 2016	-$0.47	-240.1%
Dec 31, 2015	$0.34	+341.2%
Dec 31, 2014	-$0.14	-151.6%
Dec 31, 2013	-$0.06	-185.7%
Dec 31, 2012	$0.07	+54.3%
Dec 31, 2011	$0.04	+417.3%
Dec 31, 2010	-$0.01	-106.2%
Dec 31, 2009	$0.22	-10.9%

Date	Value	Change
Dec 31, 2008	$0.24	+463.9%
Dec 31, 2007	-$0.07	+60.8%
Dec 31, 2006	-$0.17	-847.5%
Dec 31, 2005	-$0.02	+61.3%
Dec 31, 2004	-$0.05	-133.6%
Dec 31, 2003	$0.14	+120.5%
Dec 31, 2002	$0.06	-14.9%
Dec 31, 2001	$0.07	-49.8%
Dec 31, 2000	$0.15	+163.2%
Dec 31, 1999	-$0.23	-237.8%
Dec 31, 1998	$0.17	+214.2%
Dec 31, 1997	$0.05	+175.0%
Dec 31, 1996	-$0.07	-594.4%
Dec 31, 1995	$0.01	+147.1%
Dec 31, 1994	-$0.03	-138.6%
Dec 31, 1993	$0.08	+231.9%
Dec 31, 1992	-$0.06	-117.6%
Dec 31, 1991	$0.34	-

FAQ

What is the current MACD histogram of IONS?: As of today, IONS MACD histogram is $0.44

MACD Histogram Formula

Histogram = MACD − Signal

Data Sources & References

IONS Official Website www.ionis.com
Most Recent Annual Report (10-K) www.sec.gov/Archives/edgar/data/874015/000087401526000115/0000874015-26-000115-index.htm
IONS Profile on Yahoo Finance finance.yahoo.com/quote/IONS
IONS Profile on NASDAQ.com www.nasdaq.com/market-activity/stocks/ions