What is the current MACD of IONS?

As of today, IONS MACD is -$3.49

What is the current MACD signal of IONS?

As of today, IONS MACD signal is -$1.96

What is the current MACD histogram of IONS?

As of today, IONS MACD histogram is -$1.52

IONS Stock MACD History & Chart Since 1991

MACD

-$3.49$0.43-13.90%

September 18, 2026

Summary

Current Value: As of today, IONS MACD is -$3.49, down -13.90% on September 18, 2026
1-Month High: IONS MACD is currently -702.54% below its 1-month high of $0.58 set on August 28, 2026
1-Year High: IONS MACD is currently -168.74% below its 1-year high of $5.07 set on September 18, 2025
1-Month Low: IONS MACD is at its 1-month low
1-Year Low: IONS MACD is +44.79% above its 1-year low of -$6.31 reached on July 22, 2026

MACD Chart

Performance

IONS Performance
Metric	Date	Value	1D	1M	3M	YTD	1Y	3Y	5Y
MACD	Sep 18, 26	-$3.49	-13.9%	-126.7%	-837.9%	-555.3%	-168.7%	-545.4%	-554.2%
MACD Signal	Sep 18, 26	-$1.96	-24.1%	+29.2%	-512.8%	-277.2%	-139.7%	-528.0%	-555.4%
MACD Histogram	Sep 18, 26	-$1.52	-3.0%	-223.8%	-2854.1%	-347.0%	-1280.7%	-570.0%	-552.8%
Price	Sep 18, 26	$44.44	-4.9%	-25.5%	-40.0%	-43.8%	-28.0%	+3.5%	+19.4%
14-Day RSI	Sep 18, 26	25.37	-10.0%	-52.0%	-47.7%	-50.8%	-65.1%	-59.4%	-44.9%
ATR	Sep 18, 26	$2.50	-0.1%	+11.2%	+17.9%	+22.4%	+18.5%	+127.0%	+106.5%
Beta	Sep 18, 26	0.45	+2.3%	+150.0%	+7.1%	-37.5%	-43.8%	-19.6%	-54.1%
10-Day Volatility	Sep 18, 26	54.99%	-0.6%	+67.8%	+186.8%	+142.1%	+42.2%	+53.3%	+60.8%
50-Day SMA	Sep 18, 26	$55.97	-0.7%	-13.7%	-25.3%	-27.0%	+18.3%	+37.6%	+47.7%
20-Day SMA	Sep 18, 26	$56.36	-1.3%	+1.4%	-24.5%	-29.4%	+2.6%	+37.5%	+47.3%
50-Day EMA	Sep 18, 26	$58.29	-1.0%	-6.7%	-22.1%	-23.2%	+18.0%	+43.1%	+52.8%
20-Day EMA	Sep 18, 26	$53.71	-1.8%	-6.5%	-27.7%	-32.2%	-5.0%	+29.6%	+42.5%

MACD Highs

IONS MACD Highs Comparison
Period	High	Date	Current
1M	$0.58	Aug 28, 26	-702.5%
3M	$2.40	Jul 8, 26	-245.1%
6M	$2.40	Jul 8, 26	-245.1%
1Y	$5.07	Sep 18, 25	-168.7%
3Y	$5.88	Sep 12, 25	-159.3%
5Y	$5.88	Sep 12, 25	-159.3%
All	$5.88	Sep 12, 25	-159.3%

MACD Lows

IONS MACD Lows Comparison
Period	Low	Date	Current
1M	-$3.49	Sep 18, 26	at low
3M	-$6.31	Jul 22, 26	+44.8%
6M	-$6.31	Jul 22, 26	+44.8%
1Y	-$6.31	Jul 22, 26	+44.8%
3Y	-$6.31	Jul 22, 26	+44.8%
5Y	-$6.31	Jul 22, 26	+44.8%
All	-$6.31	Jul 22, 26	+44.8%

MACD History

Date	Value	Change
Sep 18, 2026	-$3.49	-555.3%
Dec 31, 2025	$0.77	+274.1%
Dec 31, 2024	-$0.44	-181.0%
Dec 31, 2023	$0.54	+155.6%
Dec 31, 2022	-$0.98	-1,666.3%
Dec 31, 2021	$0.06	-97.2%
Dec 31, 2020	$2.26	+9,820.2%
Dec 31, 2019	-$0.02	+93.2%
Dec 31, 2018	-$0.34	+66.5%
Dec 31, 2017	-$1.02	-142.8%
Dec 31, 2016	$2.38	+150.7%
Dec 31, 2015	$0.95	-67.4%
Dec 31, 2014	$2.91	+133.2%
Dec 31, 2013	$1.25	+378.4%
Dec 31, 2012	$0.26	+1,510.3%
Dec 31, 2011	-$0.02	-109.3%
Dec 31, 2010	$0.20	+284.5%
Dec 31, 2009	-$0.11	-129.9%

Date	Value	Change
Dec 31, 2008	$0.36	+280.3%
Dec 31, 2007	-$0.20	-174.2%
Dec 31, 2006	$0.27	+374.7%
Dec 31, 2005	$0.06	-75.7%
Dec 31, 2004	$0.23	+2.6%
Dec 31, 2003	$0.23	+140.4%
Dec 31, 2002	-$0.56	-8,732.3%
Dec 31, 2001	$0.01	+110.4%
Dec 31, 2000	-$0.06	+97.1%
Dec 31, 1999	-$2.20	-676.0%
Dec 31, 1998	$0.38	+151.2%
Dec 31, 1997	-$0.75	-392.6%
Dec 31, 1996	$0.25	-55.3%
Dec 31, 1995	$0.57	+587.8%
Dec 31, 1994	-$0.12	-201.0%
Dec 31, 1993	-$0.04	+77.0%
Dec 31, 1992	-$0.17	+70.0%
Dec 31, 1991	-$0.56	-

FAQ

What is the current MACD of IONS?: As of today, IONS MACD is -$3.49

MACD Formula

MACD = EMA(12) − EMA(26)

MACD Signal

-$1.96$0.38-24.12%

September 18, 2026

Summary

Current Value: As of today, IONS MACD signal is -$1.96, down -24.12% on September 18, 2026
1-Month High: IONS MACD signal is currently -2278.67% below its 1-month high of $0.09 set on September 3, 2026
1-Year High: IONS MACD signal is currently -139.69% below its 1-year high of $4.94 set on September 18, 2025
1-Month Low: IONS MACD signal is +29.19% above its 1-month low of -$2.77 reached on August 18, 2026
1-Year Low: IONS MACD signal is +62.74% above its 1-year low of -$5.26 reached on July 31, 2026

Performance

IONS Performance
Metric	Date	Value	1D	1M	3M	YTD	1Y	3Y	5Y
MACD Signal	Sep 18, 26	-$1.96	-24.1%	+29.2%	-512.8%	-277.2%	-139.7%	-528.0%	-555.4%
MACD	Sep 18, 26	-$3.49	-13.9%	-126.7%	-837.9%	-555.3%	-168.7%	-545.4%	-554.2%
MACD Histogram	Sep 18, 26	-$1.52	-3.0%	-223.8%	-2854.1%	-347.0%	-1280.7%	-570.0%	-552.8%
Price	Sep 18, 26	$44.44	-4.9%	-25.5%	-40.0%	-43.8%	-28.0%	+3.5%	+19.4%
14-Day RSI	Sep 18, 26	25.37	-10.0%	-52.0%	-47.7%	-50.8%	-65.1%	-59.4%	-44.9%
ATR	Sep 18, 26	$2.50	-0.1%	+11.2%	+17.9%	+22.4%	+18.5%	+127.0%	+106.5%
Beta	Sep 18, 26	0.45	+2.3%	+150.0%	+7.1%	-37.5%	-43.8%	-19.6%	-54.1%
10-Day Volatility	Sep 18, 26	54.99%	-0.6%	+67.8%	+186.8%	+142.1%	+42.2%	+53.3%	+60.8%
50-Day SMA	Sep 18, 26	$55.97	-0.7%	-13.7%	-25.3%	-27.0%	+18.3%	+37.6%	+47.7%
20-Day SMA	Sep 18, 26	$56.36	-1.3%	+1.4%	-24.5%	-29.4%	+2.6%	+37.5%	+47.3%
50-Day EMA	Sep 18, 26	$58.29	-1.0%	-6.7%	-22.1%	-23.2%	+18.0%	+43.1%	+52.8%
20-Day EMA	Sep 18, 26	$53.71	-1.8%	-6.5%	-27.7%	-32.2%	-5.0%	+29.6%	+42.5%

MACD Signal Highs

IONS MACD Signal Highs Comparison
Period	High	Date	Current
1M	$0.09	Sep 3, 26	-2278.7%
3M	$1.48	Jul 8, 26	-232.9%
6M	$1.48	Jul 8, 26	-232.9%
1Y	$4.94	Sep 18, 25	-139.7%
3Y	$4.94	Sep 18, 25	-139.7%
5Y	$4.94	Sep 18, 25	-139.7%
All	$4.94	Sep 18, 25	-139.7%

MACD Signal Lows

IONS MACD Signal Lows Comparison
Period	Low	Date	Current
1M	-$2.77	Aug 18, 26	+29.2%
3M	-$5.26	Jul 31, 26	+62.7%
6M	-$5.26	Jul 31, 26	+62.7%
1Y	-$5.26	Jul 31, 26	+62.7%
3Y	-$5.26	Jul 31, 26	+62.7%
5Y	-$5.26	Jul 31, 26	+62.7%
All	-$5.26	Jul 31, 26	+62.7%

MACD Signal History

Date	Value	Change
Sep 18, 2026	-$1.96	-277.2%
Dec 31, 2025	$1.11	+501.9%
Dec 31, 2024	-$0.28	-149.2%
Dec 31, 2023	$0.56	+152.6%
Dec 31, 2022	-$1.07	-1,617.8%
Dec 31, 2021	$0.07	-96.1%
Dec 31, 2020	$1.80	+283.5%
Dec 31, 2019	$0.47	+275.1%
Dec 31, 2018	-$0.27	+70.2%
Dec 31, 2017	-$0.90	-131.6%
Dec 31, 2016	$2.85	+367.4%
Dec 31, 2015	$0.61	-80.0%
Dec 31, 2014	$3.05	+134.0%
Dec 31, 2013	$1.30	+566.0%
Dec 31, 2012	$0.20	+422.6%
Dec 31, 2011	-$0.06	-128.7%
Dec 31, 2010	$0.21	+165.5%
Dec 31, 2009	-$0.32	-373.2%

Date	Value	Change
Dec 31, 2008	$0.12	+188.7%
Dec 31, 2007	-$0.13	-130.4%
Dec 31, 2006	$0.44	+488.3%
Dec 31, 2005	$0.07	-73.3%
Dec 31, 2004	$0.28	+213.1%
Dec 31, 2003	$0.09	+114.3%
Dec 31, 2002	-$0.62	-833.4%
Dec 31, 2001	-$0.07	+68.0%
Dec 31, 2000	-$0.21	+89.4%
Dec 31, 1999	-$1.97	-1,019.9%
Dec 31, 1998	$0.21	+126.8%
Dec 31, 1997	-$0.80	-345.1%
Dec 31, 1996	$0.33	-41.3%
Dec 31, 1995	$0.56	+744.2%
Dec 31, 1994	-$0.09	+27.0%
Dec 31, 1993	-$0.12	-8.8%
Dec 31, 1992	-$0.11	+88.0%
Dec 31, 1991	-$0.90	-

FAQ

What is the current MACD signal of IONS?: As of today, IONS MACD signal is -$1.96

MACD Signal Formula

Signal = EMA(9) of MACD

MACD Histogram

-$1.52$0.04-2.99%

September 18, 2026

Summary

Current Value: As of today, IONS MACD histogram is -$1.52, down -2.99% on September 18, 2026
1-Month High: IONS MACD histogram is currently -215.04% below its 1-month high of $1.33 set on August 19, 2026
1-Year High: IONS MACD histogram is currently -215.04% below its 1-year high of $1.33 set on August 19, 2026
1-Month Low: IONS MACD histogram is at its 1-month low
1-Year Low: IONS MACD histogram is +51.32% above its 1-year low of -$3.13 reached on July 15, 2026

Performance

IONS Performance
Metric	Date	Value	1D	1M	3M	YTD	1Y	3Y	5Y
MACD Histogram	Sep 18, 26	-$1.52	-3.0%	-223.8%	-2854.1%	-347.0%	-1280.7%	-570.0%	-552.8%
MACD	Sep 18, 26	-$3.49	-13.9%	-126.7%	-837.9%	-555.3%	-168.7%	-545.4%	-554.2%
MACD Signal	Sep 18, 26	-$1.96	-24.1%	+29.2%	-512.8%	-277.2%	-139.7%	-528.0%	-555.4%
Price	Sep 18, 26	$44.44	-4.9%	-25.5%	-40.0%	-43.8%	-28.0%	+3.5%	+19.4%
14-Day RSI	Sep 18, 26	25.37	-10.0%	-52.0%	-47.7%	-50.8%	-65.1%	-59.4%	-44.9%
ATR	Sep 18, 26	$2.50	-0.1%	+11.2%	+17.9%	+22.4%	+18.5%	+127.0%	+106.5%
Beta	Sep 18, 26	0.45	+2.3%	+150.0%	+7.1%	-37.5%	-43.8%	-19.6%	-54.1%
10-Day Volatility	Sep 18, 26	54.99%	-0.6%	+67.8%	+186.8%	+142.1%	+42.2%	+53.3%	+60.8%
50-Day SMA	Sep 18, 26	$55.97	-0.7%	-13.7%	-25.3%	-27.0%	+18.3%	+37.6%	+47.7%
20-Day SMA	Sep 18, 26	$56.36	-1.3%	+1.4%	-24.5%	-29.4%	+2.6%	+37.5%	+47.3%
50-Day EMA	Sep 18, 26	$58.29	-1.0%	-6.7%	-22.1%	-23.2%	+18.0%	+43.1%	+52.8%
20-Day EMA	Sep 18, 26	$53.71	-1.8%	-6.5%	-27.7%	-32.2%	-5.0%	+29.6%	+42.5%

MACD Histogram Highs

IONS MACD Histogram Highs Comparison
Period	High	Date	Current
1M	$1.33	Aug 19, 26	-215.0%
3M	$1.33	Aug 19, 26	-215.0%
6M	$1.33	Aug 19, 26	-215.0%
1Y	$1.33	Aug 19, 26	-215.0%
3Y	$2.14	Sep 9, 25	-171.3%
5Y	$2.14	Sep 9, 25	-171.3%
All	$2.48	Nov 15, 16	-161.4%

MACD Histogram Lows

IONS MACD Histogram Lows Comparison
Period	Low	Date	Current
1M	-$1.52	Sep 18, 26	at low
3M	-$3.13	Jul 15, 26	+51.3%
6M	-$3.13	Jul 15, 26	+51.3%
1Y	-$3.13	Jul 15, 26	+51.3%
3Y	-$3.13	Jul 15, 26	+51.3%
5Y	-$3.13	Jul 15, 26	+51.3%
All	-$3.13	Jul 15, 26	+51.3%

MACD Histogram History

Date	Value	Change
Sep 18, 2026	-$1.52	-347.0%
Dec 31, 2025	-$0.34	-107.4%
Dec 31, 2024	-$0.16	-861.4%
Dec 31, 2023	-$0.02	-119.1%
Dec 31, 2022	$0.09	+1,235.4%
Dec 31, 2021	-$0.01	-101.7%
Dec 31, 2020	$0.46	+193.3%
Dec 31, 2019	-$0.49	-581.0%
Dec 31, 2018	-$0.07	+37.7%
Dec 31, 2017	-$0.12	+75.5%
Dec 31, 2016	-$0.47	-240.1%
Dec 31, 2015	$0.34	+341.2%
Dec 31, 2014	-$0.14	-151.6%
Dec 31, 2013	-$0.06	-185.7%
Dec 31, 2012	$0.07	+54.3%
Dec 31, 2011	$0.04	+417.3%
Dec 31, 2010	-$0.01	-106.2%
Dec 31, 2009	$0.22	-10.9%

Date	Value	Change
Dec 31, 2008	$0.24	+463.9%
Dec 31, 2007	-$0.07	+60.8%
Dec 31, 2006	-$0.17	-847.5%
Dec 31, 2005	-$0.02	+61.3%
Dec 31, 2004	-$0.05	-133.6%
Dec 31, 2003	$0.14	+120.5%
Dec 31, 2002	$0.06	-14.9%
Dec 31, 2001	$0.07	-49.8%
Dec 31, 2000	$0.15	+163.2%
Dec 31, 1999	-$0.23	-237.8%
Dec 31, 1998	$0.17	+214.2%
Dec 31, 1997	$0.05	+175.0%
Dec 31, 1996	-$0.07	-594.4%
Dec 31, 1995	$0.01	+147.1%
Dec 31, 1994	-$0.03	-138.6%
Dec 31, 1993	$0.08	+231.9%
Dec 31, 1992	-$0.06	-117.6%
Dec 31, 1991	$0.34	-

FAQ

What is the current MACD histogram of IONS?: As of today, IONS MACD histogram is -$1.52

MACD Histogram Formula

Histogram = MACD − Signal

Data Sources & References

IONS Official Website www.ionis.com
Most Recent Annual Report (10-K) www.sec.gov/Archives/edgar/data/874015/000087401526000115/0000874015-26-000115-index.htm
IONS Profile on Yahoo Finance finance.yahoo.com/quote/IONS
IONS Profile on NASDAQ.com www.nasdaq.com/market-activity/stocks/ions