What is the current annual net margin of EXEL?

As of today, EXEL annual net margin is 33.73%

What is 1-year change in EXEL annual net margin?

EXEL annual net margin is up +40.31% year-over-year

What is 3-year change in EXEL annual net margin?

EXEL annual net margin is up +198.23% over the past 3 years

How far is EXEL annual net margin from its all-time high?

EXEL annual net margin is currently -58.27% below its historical high of 80.82% set on December 31, 2018

How does EXEL annual net margin rank versus sector peers?

EXEL annual net margin is higher than 97.81% of companies in Healthcare sector

When is EXEL next annual earnings release?

The next annual earnings release for EXEL is on February 9, 2027

What is the current quarterly net margin of EXEL?

As of today, EXEL quarterly net margin is 33.11%

What is EXEL quarterly net margin most recent change?

EXEL quarterly net margin was down -1.84% on September 1, 2026

What is 1-year change in EXEL quarterly net margin?

EXEL quarterly net margin is up +2.25% year-over-year

How far is EXEL quarterly net margin from its all-time high?

EXEL quarterly net margin is currently -45.45% below its historical high of 60.70% set on September 30, 2011

How does EXEL quarterly net margin rank versus sector peers?

EXEL quarterly net margin is higher than 96.45% of companies in Healthcare sector

When is EXEL next earnings release?

The next earnings release for EXEL is on February 9, 2027

Exelixis, Inc. (EXEL) Net Margin History & Chart Since 1998

Annual Net Margin

33.73%9.69%+40.31%

December 1, 2025

Summary

Current Value: As of today, EXEL annual net margin is 33.73%, up +40.31% on December 1, 2025
Historical Performance: EXEL annual net margin is up +198.23% over the past 3 years, up +197.97% over the past 5 years
All-Time High Comparison: EXEL annual net margin is currently -58.27% below its historical high of 80.82% set on December 31, 2018
3-Year Low Comparison: EXEL annual net margin is +198.23% above its 3-year low of 11.31% reached on an earlier date
Sector Comparison: EXEL annual net margin is higher than 97.81% of companies in Healthcare sector

Net Margin Chart

beforeafter

Performance

EXEL Performance
Metric	Date	Value	1Y	3Y	5Y	15Y
Annual Net Margin	Dec 1, 25	33.73%	+40.3%	+198.2%	+198.0%	+167.6%
Quarterly Net Margin	Sep 1, 26	33.11%	+2.3%	+10000.0%	+184.7%	-45.5%
Price	Nov 4, 26	$72.75	+92.0%	+246.4%	+284.3%	+1607.8%
PE Ratio	Nov 4, 26	21.77	+36.4%	-70.9%	-41.4%	-84.7%
Annual Revenue	Dec 1, 25	$2.32B	+7.0%	+44.0%	+134.9%	+1153.8%
Annual Net Income	Dec 1, 25	$782.57M	+50.1%	+329.3%	+600.1%	+947.6%
Annual Gross Margin	Dec 1, 25	96.39%	-0.1%	-0.0%	+0.1%	+100.0%
Annual Operating Margin	Dec 1, 25	38.48%	+21.0%	+207.6%	+245.4%	+221.4%

Net Margin Highs

EXEL Annual Net Margin Highs Comparison
Period	High	Date	Current
3Y	33.73%	Dec 1, 25	at high
5Y	33.73%	Dec 1, 25	at high
All	80.82%	Dec 31, 18	-58.3%

Net Margin Lows

EXEL Annual Net Margin Lows Comparison
Period	Low	Date	Current
3Y	11.31%	N/A	+198.2%
5Y	11.31%	Dec 30, 22	+198.2%
All	-1,091.15%	Dec 31, 14	+103.1%

Net Margin History

Year	Value	Change
2025	33.73%	+40.3%
2024	24.04%	+111.8%
2023	11.35%	+0.4%
2022	11.31%	-29.8%
2021	16.10%	+42.2%
2020	11.32%	-65.9%
2019	33.17%	-59.0%
2018	80.82%	+137.8%
2017	33.99%	+192.8%
2016	-36.64%	+91.5%
2015	-432.79%	+60.3%
2014	-1,091.15%	-39.7%
2013	-781.03%	-151.0%
2012	-311.16%	-1,290.4%

Year	Value	Change
2011	26.14%	+152.4%
2010	-49.90%	+45.7%
2009	-91.96%	+38.3%
2008	-148.97%	-52.3%
2007	-97.84%	+21.6%
2006	-124.85%	-0.0%
2005	-124.81%	+51.9%
2004	-259.65%	-41.2%
2003	-183.88%	+4.0%
2002	-191.51%	-10.3%
2001	-173.60%	+43.0%
2000	-304.58%	-71.0%
1999	-178.13%	+74.2%
1998	-689.52%	-

FAQ

What is the current annual net margin of EXEL?: As of today, EXEL annual net margin is 33.73%
What is 1-year change in EXEL annual net margin?: EXEL annual net margin is up +40.31% year-over-year
What is 3-year change in EXEL annual net margin?: EXEL annual net margin is up +198.23% over the past 3 years
How far is EXEL annual net margin from its all-time high?: EXEL annual net margin is currently -58.27% below its historical high of 80.82% set on December 31, 2018
How does EXEL annual net margin rank versus sector peers?: EXEL annual net margin is higher than 97.81% of companies in Healthcare sector
When is EXEL next annual earnings release?: The next annual earnings release for EXEL is on February 9, 2027

Net Margin Formula

Net Margin = Net Income

Revenue × 100%

Quarterly Net Margin

33.11%0.62%-1.84%

September 1, 2026

Summary

Current Value: As of today, EXEL quarterly net margin is 33.11%, down -1.84% on September 1, 2026
Historical Performance: EXEL quarterly net margin is up +2.25% year-over-year, up +14950.00% over the past 3 years
All-Time High Comparison: EXEL quarterly net margin is currently -45.45% below its historical high of 60.70% set on September 30, 2011
3-Year Low Comparison: EXEL quarterly net margin is +14950.00% above its 3-year low of 0.22% reached on an earlier date
Sector Comparison: EXEL quarterly net margin is higher than 96.45% of companies in Healthcare sector

Performance

EXEL Performance
Metric	Date	Value	3M	1Y	3Y	5Y
Quarterly Net Margin	Sep 1, 26	33.11%	-1.8%	+2.3%	+10000.0%	+184.7%
Annual Net Margin	Dec 1, 25	33.73%	–	+40.3%	+198.2%	+198.0%
Price	Nov 4, 26	$72.75	+29.9%	+92.0%	+246.4%	+284.3%
PE Ratio	Nov 4, 26	21.77	+23.8%	+36.4%	-70.9%	-41.4%
Quarterly Revenue	Sep 1, 26	$658.70M	+4.8%	+10.2%	+39.6%	+100.6%
Quarterly Net Income	Sep 1, 26	$218.10M	+2.9%	+12.7%	+10000.0%	+470.9%
Quarterly Gross Margin	Sep 1, 26	96.02%	-0.7%	-0.9%	0.0%	-0.4%
Quarterly Operating Margin	Sep 1, 26	40.75%	+3.1%	-5.0%	+1192.5%	+159.2%

Quarterly Net Margin Highs

EXEL Quarterly Net Margin Highs Comparison
Period	High	Date	Current
1Y	40.85%	Dec 1, 25	-18.9%
3Y	40.85%	Dec 1, 25	-18.9%
5Y	40.85%	Dec 1, 25	-18.9%
All	60.70%	Sep 30, 11	-45.5%

Quarterly Net Margin Lows

EXEL Quarterly Net Margin Lows Comparison
Period	Low	Date	Current
1Y	32.38%	N/A	+2.3%
3Y	0.22%	N/A	>+9999.0%
5Y	-7.12%	Dec 30, 22	+565.0%
All	-1,627.47%	Dec 31, 13	+102.0%

Quarterly Net Margin History

Month	Value	Change
Sep 2026	33.11%	-1.8%
Jun 2026	33.73%	-2.1%
Mar 2026	34.46%	-15.6%
Dec 2025	40.85%	+26.2%
Sep 2025	32.38%	-0.5%
Jun 2025	32.53%	+13.2%
Mar 2025	28.74%	+16.5%
Dec 2024	24.68%	+12.8%
Sep 2024	21.87%	-38.4%
Jun 2024	35.49%	+304.2%
Mar 2024	8.78%	-50.8%
Dec 2023	17.83%	+8,004.5%
Sep 2023	0.22%	-98.7%
Jun 2023	17.28%	+76.5%
Mar 2023	9.79%	+237.5%
Dec 2022	-7.12%	-140.0%
Sep 2022	17.78%	+5.5%
Jun 2022	16.85%	-12.5%
Mar 2022	19.26%	-8.7%
Dec 2021	21.09%	+81.3%
Sep 2021	11.63%	-53.4%
Jun 2021	24.95%	+4,128.8%
Mar 2021	0.59%	-94.4%
Dec 2020	10.51%	+175.8%
Sep 2020	-13.86%	-153.8%
Jun 2020	25.75%	+20.2%
Mar 2020	21.42%	-25.1%
Dec 2019	28.61%	-20.2%
Sep 2019	35.87%	+9.0%
Jun 2019	32.90%	-6.4%
Mar 2019	35.16%	-37.4%
Sep 2018	56.18%	+19.5%
Jun 2018	47.01%	-13.8%
Mar 2018	54.56%	+70.2%
Dec 2017	32.06%	-39.7%
Sep 2017	53.18%	+199.3%
Jun 2017	17.77%	-13.7%
Mar 2017	20.58%	-54.5%
Dec 2016	45.27%	+349.6%
Sep 2016	-18.14%	+81.1%
Jun 2016	-96.10%	+75.0%
Mar 2016	-383.89%	+8.2%
Dec 2015	-418.27%	+13.3%
Sep 2015	-482.69%	+11.0%
Jun 2015	-542.57%	-44.8%
Mar 2015	-374.63%	+52.5%
Dec 2014	-788.15%	+20.7%
Sep 2014	-994.44%	+11.1%
Jun 2014	-1,118.71%	+26.5%
Mar 2014	-1,521.28%	+6.5%
Dec 2013	-1,627.47%	-32.5%
Sep 2013	-1,228.03%	-134.2%
Jun 2013	-524.30%	-13.3%

Month	Value	Change
Mar 2013	-462.60%	+30.7%
Dec 2012	-667.94%	-171.0%
Sep 2012	-246.48%	+47.2%
Jun 2012	-467.00%	-230.5%
Mar 2012	-141.28%	-384.7%
Dec 2011	49.62%	-18.3%
Sep 2011	60.70%	+193.1%
Jun 2011	-65.22%	+14.8%
Mar 2011	-76.59%	-74.8%
Dec 2010	-43.81%	-177.5%
Sep 2010	-15.79%	+66.8%
Jun 2010	-47.51%	+53.6%
Mar 2010	-102.49%	-56.7%
Dec 2009	-65.41%	-41.3%
Sep 2009	-46.28%	+70.2%
Jun 2009	-155.39%	-2.6%
Mar 2009	-151.51%	-10.0%
Dec 2008	-137.79%	-0.1%
Sep 2008	-137.60%	+13.7%
Jun 2008	-159.37%	+1.4%
Mar 2008	-161.64%	-111.7%
Dec 2007	-76.34%	+6.4%
Sep 2007	-81.57%	+33.7%
Jun 2007	-123.11%	-12.5%
Mar 2007	-109.43%	-1.7%
Dec 2006	-107.64%	+17.6%
Sep 2006	-130.60%	-19.5%
Jun 2006	-109.25%	+35.4%
Mar 2006	-169.11%	+17.3%
Dec 2005	-204.58%	-66.5%
Sep 2005	-122.84%	-354.8%
Jun 2005	-27.01%	+87.3%
Mar 2005	-212.92%	+35.4%
Dec 2004	-329.79%	-53.6%
Sep 2004	-214.73%	+7.9%
Jun 2004	-233.23%	+3.8%
Mar 2004	-242.54%	-43.4%
Dec 2003	-169.11%	+15.8%
Sep 2003	-200.94%	-11.5%
Jun 2003	-180.25%	+3.6%
Mar 2003	-187.01%	-11.6%
Dec 2002	-167.51%	+23.8%
Sep 2002	-219.97%	+5.6%
Jun 2002	-233.07%	-46.3%
Mar 2002	-159.35%	-11.6%
Dec 2001	-142.80%	-3.3%
Sep 2001	-138.25%	+50.1%
Jun 2001	-277.25%	-68.6%
Mar 2001	-164.46%	+75.8%
Dec 2000	-680.70%	-362.8%
Sep 2000	-147.09%	+24.7%
Jun 2000	-195.37%	-59.6%
Mar 2000	-122.45%	-

FAQ

What is the current quarterly net margin of EXEL?: As of today, EXEL quarterly net margin is 33.11%
What is EXEL quarterly net margin most recent change?: EXEL quarterly net margin was down -1.84% on September 1, 2026
What is 1-year change in EXEL quarterly net margin?: EXEL quarterly net margin is up +2.25% year-over-year
How far is EXEL quarterly net margin from its all-time high?: EXEL quarterly net margin is currently -45.45% below its historical high of 60.70% set on September 30, 2011
How does EXEL quarterly net margin rank versus sector peers?: EXEL quarterly net margin is higher than 96.45% of companies in Healthcare sector
When is EXEL next earnings release?: The next earnings release for EXEL is on February 9, 2027

Net Margin Formula

Net Margin = Net Income

Revenue × 100%

Data Sources & References

EXEL Official Website www.exelixis.com
EXEL Profile on Yahoo Finance finance.yahoo.com/quote/EXEL
EXEL Profile on NASDAQ.com www.nasdaq.com/market-activity/stocks/exel