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Karyopharm Therapeutics Inc. (KPTI)

Profile

Full Name

Karyopharm Therapeutics Inc.

Ticker

NASDAQ: KPTI

Exchange

NASDAQ

Sector

Healthcare

Industry

Biotechnology

Country

United States

IPO

November 6, 2013

Indexes

Not included

Website

http://www.karyopharm.com

Employees

279

Key Details

Price

$4.43(-8.85%)

Market cap

Last Dividend

-

TTM Dividend yield

-

Annual revenue

$145.24M(-0.55% YoY)

Annual EPS

-$13.95(+25.60% YoY)

PE ratio

-

Next earnings date

Aug 6, 2025

Next ex-dividend date

N/A

Next split date

N/A

Quick Search

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    Analyst ratings

    Price

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    Current Price

    $4.43
    KPTI price is $4.43

    30-Day Relative Volume

    1.28
    KPTI 30-day relative volume is 1.28

    Price Performance

    Price Most recent change

    -8.85%
    KPTI price was down -8.85% on Jul 24, 2025

    Price YTD change

    -56.31%
    KPTI price is down -56.31% since January 1st

    Price 1-year change

    -68.81%
    KPTI price is down -68.81% year-on-year

    Price 3-year change

    -93.36%
    KPTI price is down -93.36% over the past 3 years

    Price Range

    Price All-time high

    $735.08
    KPTI price is currently -99.40% below its historical high of $735.08

    Price 3-year low

    $3.51
    KPTI price is currently +26.21% above its 3-year low

    Capitalization

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    Market cap

    Market cap

    $38.27M
    KPTI market capitalization is $38.27 million

    Market cap 3-year change

    -89.22%
    KPTI market capitalization is down -89.22% over the past 3 years

    Market cap All-time high

    $1.85B
    KPTI market capitalization is currently -97.93% below its historical high of $1.85 billion

    Market cap sector rank

    29.76%
    KPTI market capitalization is higher than 29.76% of companies in Healthcare sector

    Shares Outstanding

    Shares Outstanding 1-Year Change

    +3.98%
    KPTI shares outstanding is up +3.98% year-on-year

    Shares Outstanding 3-Year Change

    +62.41%
    KPTI shares outstanding is up +62.41% over the past 3 years

    Technical Indicators

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    Beta

    0.79
    KPTI beta is 0.79

    200-day SMA

    $8.14
    KPTI price is currently -45.55% below its 200-day simple moving average

    50-day SMA

    $4.50
    KPTI price is currently -1.57% below its 50-day simple moving average

    RSI

    50.00
    KPTI 14-day relative strength index is 50.00

    Volume

    1.28
    KPTI 30-day relative volume is 1.28

    ATR

    $0.49
    KPTI average true range is $0.49

    10-day Historical Volatility

    166.56%
    KPTI 10-day historical volatility is 166.56%

    Dividend

    Income Statement

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    Revenue

    Revenue

    $145.24M
    KPTI annual revenue is $145.24 million

    Revenue Analysts estimate

    $147.43M
    KPTI annual revenue is currently -1.49% lower than the consensus analysts' forecast

    Revenue 1-year change

    -0.55%
    KPTI annual revenue is down -0.55% year-on-year

    Revenue Sector rank

    60.07%
    KPTI annual revenue is higher than 60.07% of companies in Healthcare sector

    EPS

    EPS

    -$13.95
    KPTI annual earnings per share is -$13.95

    EPS Analysts estimate

    -$8.83
    KPTI annual earnings per share is currently +57.98% higher than the consensus analysts' forecast

    EPS 1-year change

    +25.6%
    KPTI annual earnings per share is up +25.6% year-on-year

    EPS Sector rank

    10.3%
    KPTI annual earnings per share is higher than 10.3% of companies in Healthcare sector

    Profit

    Gross profit

    $139.23M
    KPTI annual gross profit is $139.23 million

    Gross margin

    95.86%
    KPTI annual gross profit margin is 95.86%

    Operating profit

    -$119.44M
    KPTI annual operating income is -$119.44 million

    Operating margin

    -82.24%
    KPTI annual operating profit margin is -82.24%

    Net income

    -$76.42M
    KPTI annual net profit is -$76.42 million

    Net margin

    -52.62%
    KPTI annual net profit margin is -52.62%

    Expenses

    Total expenses

    $264.68M
    KPTI annual total expenses is $264.68 million

    Operating expenses

    $258.67M
    KPTI annual total operating expenses is $258.67 million

    Cost of goods sold

    $6.01M
    KPTI annual cost of goods sold is $6.01 million

    Selling, general & administrative expenses

    $115.44M
    KPTI annual SGA is $115.44 million

    Depreciation and amortization

    $340.00K
    KPTI annual depreciation & amortization is $340.00 thousand

    Interest expense

    $37.42M
    KPTI annual interest expense is $37.42 million

    Income tax

    $57.00K
    KPTI annual income tax is $57.00 thousand

    EBIT & EBITDA

    EBIT

    -$38.94M
    KPTI annual earnings before interest & taxes is -$38.94 million

    EBITDA

    -$38.60M
    KPTI annual EBITDA is -$38.60 million

    Balance Sheet

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    Assets

    Total assets

    $164.42M
    KPTI annual total assets is $164.42 million

    Non current assets

    $7.93M
    KPTI annual long term assets is $7.93 million

    Current assets

    $156.49M
    KPTI annual total current assets is $156.49 million

    Cash and cash equivalents

    $62.48M
    KPTI annual cash & cash equivalents is $62.48 million

    Accounts receivable

    $30.77M
    KPTI annual accounts receivable is $30.77 million

    Inventory

    $4.74M
    KPTI annual inventory is $4.74 million

    Liabilities

    Total liabilities

    $350.44M
    KPTI annual total liabilities is $350.44 million

    Long term liabilities

    $258.17M
    KPTI annual total long term liabilities is $258.17 million

    Current liabilities

    $92.26M
    KPTI annual total current liabilities is $92.26 million

    Accounts payable

    $5.11M
    KPTI annual accounts payable is $5.11 million

    Debt

    Total debt

    $194.52M
    KPTI annual total debt is $194.52 million

    Total debt 1-year change

    +9.89%
    KPTI annual total debt is up +9.89% year-on-year

    Long term debt

    $169.66M
    KPTI annual long term debt is $169.66 million

    Short term debt

    $24.86M
    KPTI annual short term debt is $24.86 million

    Equity & Capital

    Shareholders equity

    -$186.02M
    KPTI annual stockholders equity is -$186.02 million

    Book value

    -$186.02M
    KPTI annual book value is -$186.02 million

    Retained earnings

    -$1.56B
    KPTI annual retained earnings is -$1.56 billion

    Working capital

    $64.23M
    KPTI annual working capital is $64.23 million

    Cash Flow Statement

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    Cashflow Activities

    Cash from operations

    -$127.49M
    KPTI annual cash flow from operations is -$127.49 million

    Cash from operations 1-year change

    -37.49%
    KPTI annual cash flow from operations is down -37.49% year-on-year

    Cash from investing

    $95.47M
    KPTI annual cash flow from investing activities is $95.47 million

    Cash from investing 1-year change

    +1102.43%
    KPTI annual cash flow from investing activities is up +1102.43% year-on-year

    Cash from financing

    $41.65M
    KPTI annual cash flow from financing activities is $41.65 million

    Cash from financing 1-year change

    +3605.16%
    KPTI annual cash flow from financing activities is up +3605.16% year-on-year

    CAPEX

    CAPEX

    $142.00K
    KPTI annual capital expenditures is $142.00 thousand

    CAPEX 1-year change

    -
    KPTI annual capital expenditures 1-year change is unknown

    Free Cash Flow

    Free cash flow

    -$127.63M
    KPTI annual free cash flow is -$127.63 million

    Free cash flow 1-year change

    -37.64%
    KPTI annual free cash flow is down -37.64% year-on-year

    Profitability Ratios

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    Margins

    Gross margin

    95.86%
    KPTI annual gross profit margin is 95.86%

    Operating margin

    -82.24%
    KPTI annual operating profit margin is -82.24%

    Net margin

    -52.62%
    KPTI annual net profit margin is -52.62%

    ROA & ROE

    ROA

    -37.75%
    KPTI annual return on assets is -37.75%

    ROE

    41.08%
    KPTI annual return on equity is 41.08%

    Valuation

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    PE Ratio

    PE ratio

    -
    KPTI price to earnings ratio value is unknown

    PE ratio Sector rank

    -
    KPTI price to earnings ratio is unknown

    PB Ratio

    PB ratio

    -0.19
    KPTI price to book ratio is -0.19

    PB ratio Sector rank

    12.4%
    KPTI price to book ratio is higher than 12.4% of companies in Healthcare sector

    PS Ratio

    PS ratio

    0.27
    KPTI price to sales ratio is 0.27

    PS ratio Sector rank

    7.87%
    KPTI price to sales ratio is higher than 7.87% of companies in Healthcare sector

    Enterprise value

    Enterprise value

    $186.19M
    KPTI enterprise value is $186.19 million

    Enterprise value Sector rank

    52.08%
    KPTI enterprise value is higher than 52.08% of companies in Healthcare sector

    EV/EBITDA

    EV/EBITDA

    -9.48
    KPTI EV/EBITDA is -9.48

    EV/EBITDA Sector rank

    15.13%
    KPTI EV/EBITDA is higher than 15.13% of companies in Healthcare sector

    Financial Health

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    Liquidity

    Current ratio

    1.70
    KPTI annual current ratio is 1.70

    Quick ratio

    1.64
    KPTI annual quick ratio is 1.64

    Leverage

    Debt to equity

    -1.01
    KPTI annual debt to equity ratio is -1.01

    Interest coverage ratio

    -1.04
    KPTI annual interest coverage ratio is -1.04

    Risk & Stability

    Piotroski F-Score

    3
    KPTI piotroski f-score is 3

    Altman Z-Score

    -12.68
    KPTI altman z-score is -12.68

    Analyst ratings

    Recent major analysts updates

    Jul 16, 25 HC Wainwright & Co.
    Neutral
    May 13, 25 RBC Capital
    Outperform
    May 13, 25 Barclays
    Overweight
    May 13, 25 Baird
    Outperform
    Mar 3, 25 Baird
    Outperform
    Feb 26, 25 HC Wainwright & Co.
    Buy
    Feb 20, 25 RBC Capital
    Outperform
    Feb 20, 25 HC Wainwright & Co.
    Buy
    Feb 10, 25 RBC Capital
    Outperform
    Jan 15, 25 HC Wainwright & Co.
    Buy

    Institutional Ownership

    Screeners with KPTI included

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    • What is the ticker symbol for Karyopharm Therapeutics Inc.?
    • Does Karyopharm Therapeutics Inc. pay dividends?
    • What sector is Karyopharm Therapeutics Inc. in?
    • What industry is Karyopharm Therapeutics Inc. in?
    • What country is Karyopharm Therapeutics Inc. based in?
    • When did Karyopharm Therapeutics Inc. go public?
    • Is Karyopharm Therapeutics Inc. in the S&P 500?
    • Is Karyopharm Therapeutics Inc. in the NASDAQ 100?
    • Is Karyopharm Therapeutics Inc. in the Dow Jones?
    • When was Karyopharm Therapeutics Inc.'s last earnings report?
    • When does Karyopharm Therapeutics Inc. report earnings?

    What is the ticker symbol for Karyopharm Therapeutics Inc.?

    The ticker symbol for Karyopharm Therapeutics Inc. is NASDAQ:KPTI

    Does Karyopharm Therapeutics Inc. pay dividends?

    No, Karyopharm Therapeutics Inc. does not pay dividends

    What sector is Karyopharm Therapeutics Inc. in?

    Karyopharm Therapeutics Inc. is in the Healthcare sector

    What industry is Karyopharm Therapeutics Inc. in?

    Karyopharm Therapeutics Inc. is in the Biotechnology industry

    What country is Karyopharm Therapeutics Inc. based in?

    Karyopharm Therapeutics Inc. is headquartered in United States

    When did Karyopharm Therapeutics Inc. go public?

    Karyopharm Therapeutics Inc.'s initial public offering (IPO) was on November 6, 2013

    Is Karyopharm Therapeutics Inc. in the S&P 500?

    No, Karyopharm Therapeutics Inc. is not included in the S&P 500 index

    Is Karyopharm Therapeutics Inc. in the NASDAQ 100?

    No, Karyopharm Therapeutics Inc. is not included in the NASDAQ 100 index

    Is Karyopharm Therapeutics Inc. in the Dow Jones?

    No, Karyopharm Therapeutics Inc. is not included in the Dow Jones index

    When was Karyopharm Therapeutics Inc.'s last earnings report?

    Karyopharm Therapeutics Inc.'s most recent earnings report was on May 12, 2025

    When does Karyopharm Therapeutics Inc. report earnings?

    The next expected earnings date for Karyopharm Therapeutics Inc. is August 6, 2025
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