What is the current annual operating margin of AMGN?

As of today, AMGN annual operating margin is 40.52%

What is 1-year change in AMGN annual operating margin?

AMGN annual operating margin is up +61.95% year-over-year

What is 3-year change in AMGN annual operating margin?

AMGN annual operating margin is up +13.25% over the past 3 years

How far is AMGN annual operating margin from its all-time high?

AMGN annual operating margin is currently -7.85% below its historical high of 43.97% set on December 31, 2017

How does AMGN annual operating margin rank versus sector peers?

AMGN annual operating margin is higher than 97.48% of companies in Healthcare sector

When is AMGN next annual earnings release?

The next annual earnings release for AMGN is on February 2, 2027

What is the current quarterly operating margin of AMGN?

As of today, AMGN quarterly operating margin is 35.77%

What is AMGN quarterly operating margin most recent change?

AMGN quarterly operating margin was up +2.08% on September 30, 2026

What is 1-year change in AMGN quarterly operating margin?

AMGN quarterly operating margin is up +34.22% year-over-year

How far is AMGN quarterly operating margin from its all-time high?

AMGN quarterly operating margin is currently -45.10% below its historical high of 65.16% set on December 31, 1992

How does AMGN quarterly operating margin rank versus sector peers?

AMGN quarterly operating margin is higher than 94.95% of companies in Healthcare sector

When is AMGN next earnings release?

The next earnings release for AMGN is on February 2, 2027

Amgen Inc. (AMGN) Operating Margin History & Chart

Annual Operating Margin

40.52%15.50%+61.95%

December 31, 2025

Summary

Current Value: As of today, AMGN annual operating margin is 40.52%, up +61.95% on December 31, 2025
Historical Performance: AMGN annual operating margin is up +13.25% over the past 3 years, up +14.17% over the past 5 years
All-Time High Comparison: AMGN annual operating margin is currently -7.85% below its historical high of 43.97% set on December 31, 2017
3-Year Low Comparison: AMGN annual operating margin is +61.95% above its 3-year low of 25.02% reached on December 31, 2024
Sector Comparison: AMGN annual operating margin is higher than 97.48% of companies in Healthcare sector

Operating Margin Chart

beforeafter

Performance

AMGN Performance
Metric	Date	Value	1Y	3Y	5Y	15Y
Annual Operating Margin	Dec 31, 25	40.52%	+62.0%	+13.3%	+14.2%	+9.7%
Quarterly Operating Margin	Sep 30, 26	35.77%	+34.2%	+23.6%	+0.7%	+0.8%
Price	Nov 12, 26	$467.06	+38.9%	+74.7%	+121.0%	+707.2%
PE Ratio	Nov 12, 26	27.09	+4.2%	+42.5%	+24.4%	+88.7%
Annual Revenue	Dec 31, 25	$36.74B	+10.6%	+40.8%	+45.5%	+144.8%
Annual Operating Profit	Dec 31, 25	$14.89B	+79.1%	+59.5%	+66.2%	+168.6%
Annual Gross Margin	Dec 31, 25	70.80%	+10.3%	-6.2%	-6.3%	-14.5%
Annual Net Margin	Dec 31, 25	20.98%	+70.4%	-16.4%	-27.1%	-31.9%

Operating Margin Highs

AMGN Annual Operating Margin Highs Comparison
Period	High	Date	Current
3Y	40.52%	Dec 31, 25	at high
5Y	40.52%	Dec 31, 25	at high
All	43.97%	Dec 31, 17	-7.8%

Operating Margin Lows

AMGN Annual Operating Margin Lows Comparison
Period	Low	Date	Current
3Y	25.02%	Dec 31, 24	+62.0%
5Y	25.02%	Dec 31, 24	+62.0%
All	-292.86%	Mar 1, 84	+113.8%

Operating Margin History

Year	Value	Change
2025	40.52%	+62.0%
2024	25.02%	-17.3%
2023	30.24%	-15.5%
2022	35.78%	+1.6%
2021	35.22%	-0.8%
2020	35.49%	-13.8%
2019	41.15%	-5.3%
2018	43.45%	-1.2%
2017	43.97%	+4.7%
2016	41.99%	+9.8%
2015	38.24%	+12.1%
2014	34.12%	+7.3%
2013	31.81%	-5.5%
2012	33.65%	+0.3%
2011	33.54%	-9.2%
2010	36.95%	-2.4%
2009	37.85%	+0.7%
2008	37.59%	+4.9%
2007	35.85%	+1.1%
2006	35.46%	-9.8%
2005	39.31%	+7.3%

Year	Value	Change
2004	36.64%	-0.3%
2003	36.76%	-1.1%
2002	37.18%	-14.1%
2001	43.26%	+1.4%
2000	42.68%	-2.4%
1999	43.74%	-0.5%
1998	43.94%	+7.0%
1997	41.05%	-4.0%
1996	42.76%	+4.1%
1995	41.08%	+11.0%
1994	37.02%	-10.8%
1993	41.49%	+4.5%
1992	39.69%	+6.3%
1991	37.35%	+97.1%
1990	18.95%	+383.4%
1989	3.92%	-38.7%
1988	6.39%	+236.0%
1987	-4.70%	-10.1%
1986	-4.27%	+97.0%
1985	-143.66%	+50.9%
1984	-292.86%	-

FAQ

What is the current annual operating margin of AMGN?: As of today, AMGN annual operating margin is 40.52%
What is 1-year change in AMGN annual operating margin?: AMGN annual operating margin is up +61.95% year-over-year
What is 3-year change in AMGN annual operating margin?: AMGN annual operating margin is up +13.25% over the past 3 years
How far is AMGN annual operating margin from its all-time high?: AMGN annual operating margin is currently -7.85% below its historical high of 43.97% set on December 31, 2017
How does AMGN annual operating margin rank versus sector peers?: AMGN annual operating margin is higher than 97.48% of companies in Healthcare sector
When is AMGN next annual earnings release?: The next annual earnings release for AMGN is on February 2, 2027

Operating Margin Formula

Operating Profit Margin = Operating Income

Revenue × 100%

Quarterly Operating Margin

35.77%0.73%+2.08%

September 30, 2026

Summary

Current Value: As of today, AMGN quarterly operating margin is 35.77%, up +2.08% on September 30, 2026
Historical Performance: AMGN quarterly operating margin is up +34.22% year-over-year, up +23.60% over the past 3 years
All-Time High Comparison: AMGN quarterly operating margin is currently -45.10% below its historical high of 65.16% set on December 31, 1992
3-Year Low Comparison: AMGN quarterly operating margin is +181.43% above its 3-year low of 12.71% reached on March 31, 2024
Sector Comparison: AMGN quarterly operating margin is higher than 94.95% of companies in Healthcare sector

Performance

AMGN Performance
Metric	Date	Value	3M	1Y	3Y	5Y
Quarterly Operating Margin	Sep 30, 26	35.77%	+2.1%	+34.2%	+23.6%	+0.7%
Annual Operating Margin	Dec 31, 25	40.52%	–	+62.0%	+13.3%	+14.2%
Price	Nov 12, 26	$467.06	+12.2%	+38.9%	+74.7%	+121.0%
PE Ratio	Nov 12, 26	27.09	+4.8%	+4.2%	+42.5%	+24.4%
Quarterly Revenue	Sep 30, 26	$10.36B	+2.9%	+8.1%	+50.8%	+54.4%
Quarterly Operating Profit	Sep 30, 26	$4.60B	+30.4%	+80.1%	+131.4%	+93.0%
Quarterly Gross Margin	Sep 30, 26	73.09%	+1.4%	+7.7%	-0.8%	-3.9%
Quarterly Net Margin	Sep 30, 26	37.28%	+58.0%	+11.1%	+48.0%	+32.8%

Quarterly Operating Margin Highs

AMGN Quarterly Operating Margin Highs Comparison
Period	High	Date	Current
1Y	39.83%	Dec 31, 25	-10.2%
3Y	43.46%	Dec 31, 24	-17.7%
5Y	43.46%	Dec 31, 24	-17.7%
All	65.16%	Dec 31, 92	-45.1%

Quarterly Operating Margin Lows

AMGN Quarterly Operating Margin Lows Comparison
Period	Low	Date	Current
1Y	26.65%	N/A	+34.2%
3Y	12.71%	Mar 31, 24	+181.4%
5Y	12.71%	Mar 31, 24	+181.4%
All	-1,471.43%	Mar 1, 84	+102.4%

Quarterly Operating Margin History

Month	Value	Change
Sep 2026	35.77%	+2.1%
Jun 2026	35.04%	+12.2%
Mar 2026	31.22%	-21.6%
Dec 2025	39.83%	+49.5%
Sep 2025	26.65%	-7.6%
Jun 2025	28.84%	+108.1%
Mar 2025	13.86%	-68.1%
Dec 2024	43.46%	+83.6%
Sep 2024	23.67%	+6.4%
Jun 2024	22.25%	+75.1%
Mar 2024	12.71%	-39.6%
Dec 2023	21.06%	-27.2%
Sep 2023	28.94%	-24.0%
Jun 2023	38.10%	+23.4%
Mar 2023	30.88%	-2.9%
Dec 2022	31.79%	-19.2%
Sep 2022	39.36%	+21.3%
Jun 2022	32.46%	-18.5%
Mar 2022	39.82%	+18.9%
Dec 2021	33.50%	-5.7%
Sep 2021	35.51%	-1.2%
Jun 2021	35.93%	-0.4%
Mar 2021	36.09%	+20.1%
Dec 2020	30.06%	-20.5%
Sep 2020	37.79%	+2.9%
Jun 2020	36.74%	-2.6%
Mar 2020	37.73%	+15.7%
Dec 2019	32.62%	-24.0%
Sep 2019	42.90%	-5.5%
Jun 2019	45.41%	+2.4%
Mar 2019	44.34%	+17.2%
Dec 2018	37.84%	-4.0%
Sep 2018	39.42%	-17.1%
Jun 2018	47.54%	-3.9%
Mar 2018	49.46%	+27.0%
Dec 2017	38.94%	-12.0%
Sep 2017	44.24%	-4.0%
Jun 2017	46.10%	-1.8%
Mar 2017	46.96%	+14.4%
Dec 2016	41.06%	-5.0%
Sep 2016	43.23%	+2.4%
Jun 2016	42.20%	-4.9%
Mar 2016	44.39%	+25.9%
Dec 2015	35.25%	-12.7%
Sep 2015	40.39%	+4.1%
Jun 2015	38.80%	-10.2%
Mar 2015	43.19%	+45.1%
Dec 2014	29.77%	-15.6%
Sep 2014	35.28%	-5.7%
Jun 2014	37.43%	+15.6%
Mar 2014	32.38%	+32.8%
Dec 2013	24.38%	-32.6%
Sep 2013	36.19%	+9.6%
Jun 2013	33.03%	-3.1%
Mar 2013	34.09%	+31.0%
Dec 2012	26.03%	-25.4%
Sep 2012	34.88%	-5.2%
Jun 2012	36.78%	+1.3%
Mar 2012	36.31%	+19.9%
Dec 2011	30.28%	-14.7%
Sep 2011	35.48%	+3.8%
Jun 2011	34.19%	-2.4%
Mar 2011	35.03%	+13.5%
Dec 2010	30.86%	-19.3%
Sep 2010	38.26%	-3.3%
Jun 2010	39.55%	-4.2%
Mar 2010	41.30%	+39.3%
Dec 2009	29.64%	-30.0%
Sep 2009	42.37%	+5.6%
Jun 2009	40.13%	+1.4%
Mar 2009	39.59%	+20.3%
Dec 2008	32.92%	-13.4%
Sep 2008	38.01%	-1.1%
Jun 2008	38.44%	-2.7%
Mar 2008	39.50%	+19.6%
Dec 2007	33.03%	-5.2%
Sep 2007	34.84%	-7.5%
Jun 2007	37.66%	-0.3%

Month	Value	Change
Mar 2007	37.78%	+31.6%
Dec 2006	28.71%	-23.5%
Sep 2006	37.54%	-2.0%
Jun 2006	38.29%	+0.8%
Mar 2006	37.99%	+14.4%
Dec 2005	33.20%	-21.4%
Sep 2005	42.23%	+1.0%
Jun 2005	41.80%	+2.5%
Mar 2005	40.80%	+30.7%
Dec 2004	31.21%	-19.2%
Sep 2004	38.63%	-0.8%
Jun 2004	38.95%	-1.7%
Mar 2004	39.61%	+12.2%
Dec 2003	35.31%	-12.7%
Sep 2003	40.45%	+5.8%
Jun 2003	38.25%	+3.2%
Mar 2003	37.05%	+13.8%
Dec 2002	32.56%	-1.3%
Sep 2002	33.00%	-26.8%
Jun 2002	45.08%	-0.2%
Mar 2002	45.19%	+12.3%
Dec 2001	40.25%	-12.6%
Sep 2001	46.03%	+0.3%
Jun 2001	45.91%	+1.1%
Mar 2001	45.40%	+49.8%
Dec 2000	30.30%	-33.7%
Sep 2000	45.73%	+3.3%
Jun 2000	44.27%	-2.3%
Mar 2000	45.31%	+14.0%
Dec 1999	39.73%	-13.7%
Sep 1999	46.03%	+4.6%
Jun 1999	44.02%	-0.4%
Mar 1999	44.19%	-2.5%
Dec 1998	45.31%	+2.7%
Sep 1998	44.11%	+0.5%
Jun 1998	43.90%	+4.4%
Mar 1998	42.05%	+11.7%
Dec 1997	37.64%	+1.1%
Sep 1997	37.23%	-12.8%
Jun 1997	42.69%	+4.0%
Mar 1997	41.04%	+1.9%
Dec 1996	40.29%	-4.4%
Sep 1996	42.13%	-0.6%
Jun 1996	42.40%	+8.8%
Mar 1996	38.98%	-2.1%
Dec 1995	39.80%	-7.4%
Sep 1995	42.96%	+6.7%
Jun 1995	40.26%	+10.5%
Mar 1995	36.45%	-16.8%
Dec 1994	43.82%	-0.4%
Sep 1994	43.98%	+3.6%
Jun 1994	42.46%	+1.0%
Mar 1994	42.04%	+9.7%
Dec 1993	38.33%	-9.9%
Sep 1993	42.56%	+3.3%
Jun 1993	41.19%	+1.1%
Mar 1993	40.76%	-37.4%
Dec 1992	65.16%	+64.6%
Sep 1992	39.58%	+5.2%
Jun 1992	37.62%	-2.5%
Mar 1992	38.57%	-1.3%
Dec 1991	39.07%	+9.1%
Sep 1991	35.81%	+173.7%
Jun 1991	-48.56%	-230.5%
Mar 1991	37.20%	+213.8%
Dec 1990	-32.68%	-265.1%
Sep 1990	19.80%	+5.9%
Jun 1990	18.69%	+0.5%
Mar 1990	18.60%	+3.8%
Dec 1989	17.92%	+44.9%
Sep 1989	12.37%	+106.5%
Jun 1989	5.99%	+101.2%
Mar 1989	-514.75%	+36.2%
Mar 1988	-807.27%	-253.4%
Mar 1987	-228.42%	+8.3%
Mar 1986	-249.21%	+51.9%
Mar 1985	-517.86%	+64.8%
Mar 1984	-1,471.43%	-

FAQ

What is the current quarterly operating margin of AMGN?: As of today, AMGN quarterly operating margin is 35.77%
What is AMGN quarterly operating margin most recent change?: AMGN quarterly operating margin was up +2.08% on September 30, 2026
What is 1-year change in AMGN quarterly operating margin?: AMGN quarterly operating margin is up +34.22% year-over-year
How far is AMGN quarterly operating margin from its all-time high?: AMGN quarterly operating margin is currently -45.10% below its historical high of 65.16% set on December 31, 1992
How does AMGN quarterly operating margin rank versus sector peers?: AMGN quarterly operating margin is higher than 94.95% of companies in Healthcare sector
When is AMGN next earnings release?: The next earnings release for AMGN is on February 2, 2027

Operating Margin Formula

Operating Profit Margin = Operating Income

Revenue × 100%

Data Sources & References

AMGN Official Website www.amgen.com
Most Recent Annual Report (10-K) www.sec.gov/Archives/edgar/data/318154/000031815426000003/0000318154-26-000003-index.htm
AMGN Profile on Yahoo Finance finance.yahoo.com/quote/AMGN
AMGN Profile on NASDAQ.com www.nasdaq.com/market-activity/stocks/amgn