What is the current annual ROE of VRTX?

As of today, VRTX annual ROE is 22.54%

What is 1-year change in VRTX annual ROE?

VRTX annual ROE is up +815.56% year-over-year

What is 3-year change in VRTX annual ROE?

VRTX annual ROE is down -18.54% over the past 3 years

How far is VRTX annual ROE from its all-time high?

VRTX annual ROE is currently -65.02% below its historical high of 64.43% set on December 31, 2018

How does VRTX annual ROE rank versus sector peers?

VRTX annual ROE is higher than 85.78% of companies in Healthcare sector

When is VRTX next annual earnings release?

As of today, the next annual earnings release for VRTX has not been scheduled

What is the current quarterly ROE of VRTX?

As of today, VRTX quarterly ROE is 23.74%

What is VRTX quarterly ROE most recent change?

VRTX quarterly ROE was down -2.59% on June 30, 2026

What is 1-year change in VRTX quarterly ROE?

VRTX quarterly ROE is up +5.04% year-over-year

How far is VRTX quarterly ROE from its all-time high?

VRTX quarterly ROE is currently -66.88% below its historical high of 71.67% set on December 31, 2018

How does VRTX quarterly ROE rank versus sector peers?

VRTX quarterly ROE is higher than 84.34% of companies in Healthcare sector

When is VRTX next earnings release?

The next earnings release for VRTX is on November 2, 2026

VRTX ROE History & Chart Since 1990

Annual ROE

22.54%25.69%+815.56%

December 31, 2025

Summary

Current Value: As of today, VRTX annual ROE is 22.54%, up +815.56% on December 31, 2025
Historical Performance: VRTX annual ROE is down -18.54% over the past 3 years, down -38.60% over the past 5 years
All-Time High Comparison: VRTX annual ROE is currently -65.02% below its historical high of 64.43% set on December 31, 2018
3-Year Low Comparison: VRTX annual ROE is +815.56% above its 3-year low of -3.15% reached on December 31, 2024
Sector Comparison: VRTX annual ROE is higher than 85.78% of companies in Healthcare sector

ROE Chart

beforeafter

Performance

VRTX Performance
Metric	Date	Value	1Y	3Y	5Y	15Y
Annual ROE	Dec 31, 25	22.54%	+815.6%	-18.5%	-38.6%	+123.9%
Quarterly ROE	Jun 30, 26	23.74%	+5.0%	-2.9%	+1.4%	+117.5%
Price	Aug 18, 26	$528.19	+35.5%	+53.2%	+171.2%	+1066.2%
PE Ratio	Aug 18, 26	30.73	+10.3%	+15.3%	+19.5%	–
Annual Revenue	Dec 31, 25	$12.07B	+9.9%	+38.0%	+94.5%	+8322.0%
Annual Net Income	Dec 31, 25	$3.95B	+838.1%	+19.0%	+45.8%	+623.9%
Annual Shareholders Equity	Dec 31, 25	$18.67B	+13.8%	+34.2%	+114.9%	+3603.7%
Annual ROA	Dec 31, 25	16.06%	+792.2%	-23.7%	-40.6%	+139.2%

ROE Highs

VRTX Annual ROE Highs Comparison
Period	High	Date	Current
3Y	27.67%	N/A	-18.5%
5Y	36.71%	N/A	-38.6%
All	64.43%	Dec 31, 18	-65.0%

ROE Lows

VRTX Annual ROE Lows Comparison
Period	Low	Date	Current
3Y	-3.15%	Dec 31, 24	+815.6%
5Y	-3.15%	Dec 31, 24	+815.6%
All	-180.27%	Dec 31, 08	+112.5%

ROE History

Year	Value	Change
2025	22.54%	+815.6%
2024	-3.15%	-113.7%
2023	22.99%	-16.9%
2022	27.67%	+11.0%
2021	24.93%	-32.1%
2020	36.71%	+64.1%
2019	22.37%	-65.3%
2018	64.43%	+1,093.1%
2017	5.40%	+178.1%
2016	-6.91%	+87.1%
2015	-53.72%	+11.2%
2014	-60.49%	-14.0%
2013	-53.08%	-1,041.5%
2012	-4.65%	-183.6%
2011	5.56%	+105.9%
2010	-94.31%	+2.0%
2009	-96.19%	+46.6%
2008	-180.27%	-79.0%

Year	Value	Change
2007	-100.69%	-80.4%
2006	-55.81%	+62.3%
2005	-148.15%	-1.7%
2004	-145.65%	-56.2%
2003	-93.25%	-266.5%
2002	-25.44%	-60.3%
2001	-15.87%	-29.7%
2000	-12.24%	+32.0%
1999	-17.99%	-42.0%
1998	-12.67%	-29.9%
1997	-9.75%	+73.7%
1996	-37.02%	-64.0%
1995	-22.57%	+0.6%
1994	-22.70%	-620.6%
1993	4.36%	+124.7%
1992	-17.67%	+0.6%
1991	-17.77%	+78.5%
1990	-82.69%	-

FAQ

What is the current annual ROE of VRTX?: As of today, VRTX annual ROE is 22.54%
What is 1-year change in VRTX annual ROE?: VRTX annual ROE is up +815.56% year-over-year
What is 3-year change in VRTX annual ROE?: VRTX annual ROE is down -18.54% over the past 3 years
How far is VRTX annual ROE from its all-time high?: VRTX annual ROE is currently -65.02% below its historical high of 64.43% set on December 31, 2018
How does VRTX annual ROE rank versus sector peers?: VRTX annual ROE is higher than 85.78% of companies in Healthcare sector
When is VRTX next annual earnings release?: As of today, the next annual earnings release for VRTX has not been scheduled

ROE Formula

ROE = Net Income

Shareholders Equity × 100%

Quarterly ROE

23.74%0.63%-2.59%

June 30, 2026

Summary

Current Value: As of today, VRTX quarterly ROE is 23.74%, down -2.59% on June 30, 2026
Historical Performance: VRTX quarterly ROE is up +5.04% year-over-year, down -2.94% over the past 3 years
All-Time High Comparison: VRTX quarterly ROE is currently -66.88% below its historical high of 71.67% set on December 31, 2018
3-Year Low Comparison: VRTX quarterly ROE is +493.05% above its 3-year low of -6.04% reached on March 31, 2025
Sector Comparison: VRTX quarterly ROE is higher than 84.34% of companies in Healthcare sector

Performance

VRTX Performance
Metric	Date	Value	3M	1Y	3Y	5Y
Quarterly ROE	Jun 30, 26	23.74%	-2.6%	+5.0%	-2.9%	+1.4%
Annual ROE	Dec 31, 25	22.54%	–	+815.6%	-18.5%	-38.6%
Price	Aug 18, 26	$528.19	+21.0%	+35.5%	+53.2%	+171.2%
PE Ratio	Aug 18, 26	30.73	+18.7%	+10.3%	+15.3%	+19.5%
Quarterly Revenue	Jun 30, 26	$3.34B	+11.0%	+12.0%	+34.6%	+84.7%
Quarterly Net Income	Jun 30, 26	$1.10B	+6.6%	+6.5%	+20.1%	+1543.4%
Quarterly Shareholders Equity	Jun 30, 26	$20.25B	+4.6%	+17.9%	+30.9%	+120.2%
Quarterly ROA	Jun 30, 26	17.08%	-2.1%	+5.6%	-8.9%	-1.2%

Quarterly ROE Highs

VRTX Quarterly ROE Highs Comparison
Period	High	Date	Current
1Y	24.37%	Mar 31, 26	-2.6%
3Y	24.46%	N/A	-2.9%
5Y	30.92%	Jun 30, 22	-23.2%
All	71.67%	Dec 31, 18	-66.9%

Quarterly ROE Lows

VRTX Quarterly ROE Lows Comparison
Period	Low	Date	Current
1Y	22.13%	Sep 30, 25	+7.3%
3Y	-6.04%	Mar 31, 25	+493.1%
5Y	-6.04%	Mar 31, 25	+493.1%
All	-290.95%	Sep 30, 05	+108.2%

Quarterly ROE History

Month	Value	Change
Jun 2026	23.74%	-2.6%
Mar 2026	24.37%	+6.1%
Dec 2025	22.97%	+3.8%
Sep 2025	22.13%	-2.1%
Jun 2025	22.60%	+474.2%
Mar 2025	-6.04%	-87.0%
Dec 2024	-3.23%	-11.8%
Sep 2024	-2.89%	+2.4%
Jun 2024	-2.96%	-112.2%
Mar 2024	24.35%	+4.8%
Dec 2023	23.23%	-1.8%
Sep 2023	23.65%	-3.3%
Jun 2023	24.46%	-3.6%
Mar 2023	25.38%	-8.5%
Dec 2022	27.74%	-5.9%
Sep 2022	29.49%	-4.6%
Jun 2022	30.92%	+22.9%
Mar 2022	25.16%	-0.1%
Dec 2021	25.19%	+3.1%
Sep 2021	24.44%	+4.4%
Jun 2021	23.42%	-32.5%
Mar 2021	34.72%	-5.5%
Dec 2020	36.76%	-8.6%
Sep 2020	40.22%	+17.5%
Jun 2020	34.24%	+25.1%
Mar 2020	27.38%	+19.0%
Dec 2019	23.01%	-51.3%
Sep 2019	47.25%	-14.2%
Jun 2019	55.07%	-10.8%
Mar 2019	61.72%	-13.9%
Dec 2018	71.67%	+157.4%
Sep 2018	27.84%	+147.5%
Jun 2018	11.25%	+219.6%
Mar 2018	3.52%	-32.6%
Dec 2017	5.22%	+392.5%
Sep 2017	1.06%	-94.3%
Jun 2017	18.48%	+19.7%
Mar 2017	15.44%	+317.8%
Dec 2016	-7.09%	+57.3%
Sep 2016	-16.62%	+24.6%
Jun 2016	-22.03%	+45.0%
Mar 2016	-40.07%	+27.8%
Dec 2015	-55.53%	+14.0%
Sep 2015	-64.58%	+8.3%
Jun 2015	-70.41%	-12.3%
Mar 2015	-62.69%	-1.5%
Dec 2014	-61.75%	-5.9%
Sep 2014	-58.29%	-12.4%
Jun 2014	-51.88%	-12.7%
Mar 2014	-46.02%	+11.6%
Dec 2013	-52.06%	-16.7%
Sep 2013	-44.62%	-16.8%
Jun 2013	-38.20%	+1.5%
Mar 2013	-38.77%	-765.4%
Dec 2012	-4.48%	-122.2%
Sep 2012	20.14%	-61.2%
Jun 2012	51.91%	+25.3%
Mar 2012	41.43%	+550.4%
Dec 2011	6.37%	+110.5%
Sep 2011	-60.44%	+55.4%
Jun 2011	-135.50%	-19.1%
Mar 2011	-113.79%	-22.7%
Dec 2010	-92.75%	-5.6%
Sep 2010	-87.81%	-10.9%
Jun 2010	-79.20%	-1.5%
Mar 2010	-78.03%	+17.9%
Dec 2009	-95.00%	+20.1%
Sep 2009	-118.83%	+11.2%
Jun 2009	-133.87%	+6.4%
Mar 2009	-143.05%	+12.6%
Dec 2008	-163.74%	-21.6%
Sep 2008	-134.66%	-10.6%

Month	Value	Change
Jun 2008	-121.71%	-9.1%
Mar 2008	-111.52%	-15.4%
Dec 2007	-96.61%	-31.3%
Sep 2007	-73.59%	-11.6%
Jun 2007	-65.96%	-6.8%
Mar 2007	-61.76%	+1.3%
Dec 2006	-62.60%	+26.3%
Sep 2006	-84.90%	+37.8%
Jun 2006	-136.44%	+6.4%
Mar 2006	-145.74%	+25.1%
Dec 2005	-194.70%	+33.1%
Sep 2005	-290.95%	-16.4%
Jun 2005	-249.98%	-8.1%
Mar 2005	-231.28%	-58.6%
Dec 2004	-145.83%	-36.3%
Sep 2004	-106.96%	-1.7%
Jun 2004	-105.21%	-6.0%
Mar 2004	-99.28%	-53.6%
Dec 2003	-64.65%	-19.2%
Sep 2003	-54.23%	-55.8%
Jun 2003	-34.80%	-118.9%
Mar 2003	-15.90%	+37.1%
Dec 2002	-25.27%	-26.0%
Sep 2002	-20.06%	-3.7%
Jun 2002	-19.35%	-9.3%
Mar 2002	-17.71%	-17.1%
Dec 2001	-15.12%	-7.6%
Sep 2001	-14.05%	+5.6%
Jun 2001	-14.88%	-83.3%
Mar 2001	-8.12%	+33.5%
Dec 2000	-12.21%	+2.2%
Sep 2000	-12.48%	-64.4%
Jun 2000	-7.59%	+59.1%
Mar 2000	-18.57%	-0.7%
Dec 1999	-18.45%	+22.6%
Sep 1999	-23.83%	-33.6%
Jun 1999	-17.84%	-6.7%
Mar 1999	-16.72%	-30.5%
Dec 1998	-12.81%	-26.2%
Sep 1998	-10.15%	+9.9%
Jun 1998	-11.27%	-39.0%
Mar 1998	-8.11%	-1.9%
Dec 1997	-7.96%	-3.6%
Sep 1997	-7.68%	+21.6%
Jun 1997	-9.80%	+65.2%
Mar 1997	-28.17%	+31.0%
Dec 1996	-40.82%	+1.6%
Sep 1996	-41.49%	+10.7%
Jun 1996	-46.48%	-70.0%
Mar 1996	-27.34%	-20.0%
Dec 1995	-22.78%	+14.4%
Sep 1995	-26.61%	-16.5%
Jun 1995	-22.84%	-21.4%
Mar 1995	-18.82%	+2.5%
Dec 1994	-19.30%	-284.5%
Sep 1994	-5.02%	-25.2%
Jun 1994	-4.01%	-211.7%
Mar 1994	3.59%	-17.7%
Dec 1993	4.36%	+119.7%
Sep 1993	-22.11%	-9.5%
Jun 1993	-20.20%	+7.9%
Mar 1993	-21.94%	-26.3%
Dec 1992	-17.37%	-12.0%
Sep 1992	-15.51%	+6.0%
Jun 1992	-16.50%	+17.0%
Mar 1992	-19.87%	+14.5%
Dec 1991	-23.23%	+43.7%
Sep 1991	-41.29%	+66.5%
Jun 1991	-123.08%	-42.2%
Mar 1991	-86.54%	-4.7%
Dec 1990	-82.69%	-

FAQ

What is the current quarterly ROE of VRTX?: As of today, VRTX quarterly ROE is 23.74%
What is VRTX quarterly ROE most recent change?: VRTX quarterly ROE was down -2.59% on June 30, 2026
What is 1-year change in VRTX quarterly ROE?: VRTX quarterly ROE is up +5.04% year-over-year
How far is VRTX quarterly ROE from its all-time high?: VRTX quarterly ROE is currently -66.88% below its historical high of 71.67% set on December 31, 2018
How does VRTX quarterly ROE rank versus sector peers?: VRTX quarterly ROE is higher than 84.34% of companies in Healthcare sector
When is VRTX next earnings release?: The next earnings release for VRTX is on November 2, 2026

ROE Formula

ROE = Net Income

Shareholders Equity × 100%

Data Sources & References

VRTX Official Website www.vrtx.com
Most Recent Annual Report (10-K) www.sec.gov/Archives/edgar/data/875320/000087532026000056/0000875320-26-000056-index.htm
VRTX Profile on Yahoo Finance finance.yahoo.com/quote/VRTX
VRTX Profile on NASDAQ.com www.nasdaq.com/market-activity/stocks/vrtx