What is the current annual net margin of NBIX?

As of today, NBIX annual net margin is 16.73%

What is 1-year change in NBIX annual net margin?

NBIX annual net margin is up +15.46% year-over-year

What is 3-year change in NBIX annual net margin?

NBIX annual net margin is up +61.18% over the past 3 years

How far is NBIX annual net margin from its all-time high?

NBIX annual net margin is currently -65.53% below its historical high of 48.53% set on December 31, 2011

How does NBIX annual net margin rank versus sector peers?

NBIX annual net margin is higher than 91.38% of companies in Healthcare sector

When is NBIX next annual earnings release?

The next annual earnings release for NBIX is on February 11, 2027

What is the current quarterly net margin of NBIX?

As of today, NBIX quarterly net margin is 18.39%

What is NBIX quarterly net margin most recent change?

NBIX quarterly net margin was up +22.11% on September 30, 2026

What is 1-year change in NBIX quarterly net margin?

NBIX quarterly net margin is down -30.24% year-over-year

How far is NBIX quarterly net margin from its all-time high?

NBIX quarterly net margin is currently -75.60% below its historical high of 75.38% set on September 30, 2011

How does NBIX quarterly net margin rank versus sector peers?

NBIX quarterly net margin is higher than 89.23% of companies in Healthcare sector

When is NBIX next earnings release?

The next earnings release for NBIX is on February 11, 2027

NBIX Net Margin History & Chart Since 1996

Annual Net Margin

16.73%2.24%+15.46%

December 31, 2025

Summary

Current Value: As of today, NBIX annual net margin is 16.73%, up +15.46% on December 31, 2025
Historical Performance: NBIX annual net margin is up +61.18% over the past 3 years, down -57.04% over the past 5 years
All-Time High Comparison: NBIX annual net margin is currently -65.53% below its historical high of 48.53% set on December 31, 2011
3-Year Low Comparison: NBIX annual net margin is +61.18% above its 3-year low of 10.38% reached on an earlier date
Sector Comparison: NBIX annual net margin is higher than 91.38% of companies in Healthcare sector

Net Margin Chart

beforeafter

Performance

NBIX Performance
Metric	Date	Value	1Y	3Y	5Y	15Y
Annual Net Margin	Dec 31, 25	16.73%	+15.5%	+61.2%	-57.0%	+170.3%
Quarterly Net Margin	Sep 30, 26	18.39%	-30.2%	+10.4%	+142.0%	-75.6%
Price	Nov 5, 26	$159.76	+3.9%	+42.1%	+71.4%	+2134.4%
PE Ratio	Nov 5, 26	23.69	-35.5%	-60.6%	+16.1%	+132.0%
Annual Revenue	Dec 31, 25	$2.86B	+21.4%	+92.2%	+173.5%	+8438.5%
Annual Net Income	Dec 31, 25	$478.60M	+40.2%	+209.8%	+17.5%	+6106.5%
Annual Gross Margin	Dec 31, 25	98.18%	+0.6%	+0.8%	-0.0%	+2.6%
Annual Operating Margin	Dec 31, 25	22.25%	-12.2%	+32.1%	-28.9%	+168.2%

Net Margin Highs

NBIX Annual Net Margin Highs Comparison
Period	High	Date	Current
3Y	16.73%	Dec 31, 25	at high
5Y	38.94%	N/A	-57.0%
All	48.53%	Dec 31, 11	-65.5%

Net Margin Lows

NBIX Annual Net Margin Lows Comparison
Period	Low	Date	Current
3Y	10.38%	N/A	+61.2%
5Y	7.90%	Dec 31, 21	+111.8%
All	-16.94%	Dec 31, 07	+100.1%

Net Margin History

Year	Value	Change
2025	16.73%	+15.5%
2024	14.49%	+9.5%
2023	13.23%	+27.5%
2022	10.38%	+31.4%
2021	7.90%	-79.7%
2020	38.94%	+728.5%
2019	4.70%	+0.4%
2018	4.68%	+105.3%
2017	-88.19%	+90.6%
2016	-940.60%	-109.1%
2015	-449.84%	+71.5%
2013	-1,578.97%	>-9,900.0%
2012	9.46%	-80.5%
2011	48.53%	+304.1%
2010	-23.78%	+98.6%

Year	Value	Change
2009	-1,728.34%	+22.5%
2008	-2,229.26%	+86.8%
2007	-16.94%	-6,098.1%
2006	-273.25%	-1,425.7%
2005	-17.91%	+66.7%
2004	-53.74%	-147.1%
2003	-21.75%	+95.8%
2002	-523.89%	-485.4%
2001	-89.50%	+54.7%
2000	-197.48%	-97.1%
1999	-100.18%	+19.5%
1998	-124.43%	-734.5%
1997	19.61%	-35.9%
1996	30.57%	-

FAQ

What is the current annual net margin of NBIX?: As of today, NBIX annual net margin is 16.73%
What is 1-year change in NBIX annual net margin?: NBIX annual net margin is up +15.46% year-over-year
What is 3-year change in NBIX annual net margin?: NBIX annual net margin is up +61.18% over the past 3 years
How far is NBIX annual net margin from its all-time high?: NBIX annual net margin is currently -65.53% below its historical high of 48.53% set on December 31, 2011
How does NBIX annual net margin rank versus sector peers?: NBIX annual net margin is higher than 91.38% of companies in Healthcare sector
When is NBIX next annual earnings release?: The next annual earnings release for NBIX is on February 11, 2027

Net Margin Formula

Net Margin = Net Income

Revenue × 100%

Quarterly Net Margin

18.39%3.33%+22.11%

September 30, 2026

Summary

Current Value: As of today, NBIX quarterly net margin is 18.39%, up +22.11% on September 30, 2026
Historical Performance: NBIX quarterly net margin is down -30.24% year-over-year, up +10.38% over the past 3 years
All-Time High Comparison: NBIX quarterly net margin is currently -75.60% below its historical high of 75.38% set on September 30, 2011
3-Year Low Comparison: NBIX quarterly net margin is +1232.61% above its 3-year low of 1.38% reached on March 31, 2025
Sector Comparison: NBIX quarterly net margin is higher than 89.23% of companies in Healthcare sector

Performance

NBIX Performance
Metric	Date	Value	3M	1Y	3Y	5Y
Quarterly Net Margin	Sep 30, 26	18.39%	+22.1%	-30.2%	+10.4%	+142.0%
Annual Net Margin	Dec 31, 25	16.73%	–	+15.5%	+61.2%	-57.0%
Price	Nov 5, 26	$159.76	-1.1%	+3.9%	+42.1%	+71.4%
PE Ratio	Nov 5, 26	23.69	+0.1%	-35.5%	-60.6%	+16.1%
Quarterly Revenue	Sep 30, 26	$1.12B	+17.1%	+41.2%	+125.1%	+279.3%
Quarterly Net Income	Sep 30, 26	$206.50M	+43.0%	-1.4%	+148.5%	+817.8%
Quarterly Gross Margin	Sep 30, 26	94.51%	-1.4%	-3.8%	-2.4%	-3.2%
Quarterly Operating Margin	Sep 30, 26	30.55%	+91.5%	+1.5%	+7.9%	+103.3%

Quarterly Net Margin Highs

NBIX Quarterly Net Margin Highs Comparison
Period	High	Date	Current
1Y	26.36%	N/A	-30.2%
3Y	28.67%	Dec 31, 23	-35.9%
5Y	28.67%	Dec 31, 23	-35.9%
All	75.38%	Sep 30, 11	-75.6%

Quarterly Net Margin Lows

NBIX Quarterly Net Margin Lows Comparison
Period	Low	Date	Current
1Y	15.06%	Jun 30, 26	+22.1%
3Y	1.38%	Mar 31, 25	+1232.6%
5Y	-18.22%	Mar 31, 23	+200.9%
All	-54.93%	Jun 30, 07	+100.0%

Quarterly Net Margin History

Month	Value	Change
Sep 2026	18.39%	+22.1%
Jun 2026	15.06%	-38.0%
Mar 2026	24.30%	+27.4%
Dec 2025	19.08%	-27.6%
Sep 2025	26.36%	+68.5%
Jun 2025	15.64%	+1,033.3%
Mar 2025	1.38%	-91.6%
Dec 2024	16.43%	-21.2%
Sep 2024	20.86%	+89.5%
Jun 2024	11.01%	+30.8%
Mar 2024	8.42%	-70.6%
Dec 2023	28.67%	+72.1%
Sep 2023	16.66%	-21.0%
Jun 2023	21.10%	+215.8%
Mar 2023	-18.22%	-184.4%
Dec 2022	21.60%	+22.3%
Sep 2022	17.66%	+495.1%
Jun 2022	-4.47%	-199.8%
Mar 2022	4.48%	+291.5%
Dec 2021	-2.34%	-130.8%
Sep 2021	7.60%	-48.1%
Jun 2021	14.64%	+7.9%
Mar 2021	13.57%	+160.9%
Sep 2020	-22.28%	-184.7%
Jun 2020	26.32%	+66.9%
Mar 2020	15.77%	+13.2%
Dec 2019	13.93%	-42.5%
Sep 2019	24.22%	-13.4%
Jun 2019	27.96%	+137.9%
Mar 2019	-73.78%	-636.6%
Dec 2018	13.75%	-58.9%
Sep 2018	33.45%	+648.4%
Jun 2018	-6.10%	+89.6%
Mar 2018	-58.83%	-907.0%
Dec 2017	7.29%	+139.8%
Sep 2017	-18.31%	+98.1%
Jun 2017	-946.88%	-637.3%
Mar 2016	-128.43%	-2,029.9%
Mar 2015	-6.03%	+99.6%
Dec 2013	-1,457.81%	+4.5%
Sep 2013	-1,526.89%	+9.0%
Jun 2013	-1,676.99%	-1.4%
Mar 2013	-1,654.11%	-3,925.4%
Dec 2012	43.24%	+231.4%
Sep 2012	-32.90%	-594.1%
Jun 2012	-4.74%	+39.7%
Mar 2012	-7.86%	-165.6%
Dec 2011	11.98%	-84.1%
Sep 2011	75.38%	+363.9%
Jun 2011	16.25%	-29.4%
Mar 2011	23.03%	+26.5%
Dec 2010	18.21%	-21.1%
Sep 2010	23.07%	+120.8%
Jun 2010	-110.96%	+90.3%
Mar 2010	-1,146.88%	-7.2%

Month	Value	Change
Dec 2009	-1,069.73%	+4.1%
Sep 2009	-1,115.55%	+46.5%
Jun 2009	-2,084.58%	+20.8%
Mar 2009	-2,632.53%	+33.5%
Dec 2008	-3,958.02%	-70.1%
Sep 2008	-2,327.33%	+18.5%
Jun 2008	-2,857.08%	-137.4%
Mar 2008	-1,203.71%	+95.0%
Dec 2007	-24.06%	-376.9%
Sep 2007	-5,044.44%	+90.8%
Jun 2007	-54.93%	-122.1%
Mar 2007	-24.73%	>-9,900.0%
Dec 2006	-155.85%	+95.7%
Sep 2006	-3,644.60%	-1,127.4%
Jun 2006	-296.94%	-123.3%
Mar 2006	-132.99%	+21.5%
Dec 2005	-169.43%	-519.5%
Sep 2005	40.39%	+339.0%
Jun 2005	-16.90%	+89.4%
Mar 2005	-158.72%	-42.3%
Dec 2004	-111.52%	-2,247.8%
Sep 2004	-4.75%	+93.6%
Jun 2004	-73.97%	-1.2%
Mar 2004	-73.08%	-720.9%
Dec 2003	11.77%	+135.0%
Sep 2003	-33.61%	-47.8%
Jun 2003	-22.74%	+35.9%
Mar 2003	-35.50%	+96.5%
Dec 2002	-1,000.18%	-146.3%
Sep 2002	-406.06%	+13.1%
Jun 2002	-467.26%	-46.9%
Mar 2002	-318.01%	-179.3%
Dec 2001	-113.85%	-1,080.6%
Sep 2001	11.61%	+102.9%
Jun 2001	-400.96%	-22.0%
Mar 2001	-328.64%	-223.9%
Dec 2000	-101.47%	+33.6%
Sep 2000	-152.83%	+13.4%
Jun 2000	-176.48%	+18.9%
Mar 2000	-217.67%	-147.8%
Dec 1999	-87.85%	-4.3%
Sep 1999	-84.25%	+30.8%
Jun 1999	-121.71%	-5.7%
Mar 1999	-115.15%	+22.4%
Dec 1998	-148.31%	-85.7%
Sep 1998	-79.88%	+77.1%
Jun 1998	-348.17%	-1,115.3%
Mar 1998	-28.65%	>-9,900.0%
Dec 1997	0.00%	-100.0%
Sep 1997	12.90%	+520.2%
Jun 1997	2.08%	-95.5%
Mar 1997	46.07%	-4.8%
Dec 1996	48.39%	+366.2%
Sep 1996	-18.18%	-155.5%
Jun 1996	32.73%	-

FAQ

What is the current quarterly net margin of NBIX?: As of today, NBIX quarterly net margin is 18.39%
What is NBIX quarterly net margin most recent change?: NBIX quarterly net margin was up +22.11% on September 30, 2026
What is 1-year change in NBIX quarterly net margin?: NBIX quarterly net margin is down -30.24% year-over-year
How far is NBIX quarterly net margin from its all-time high?: NBIX quarterly net margin is currently -75.60% below its historical high of 75.38% set on September 30, 2011
How does NBIX quarterly net margin rank versus sector peers?: NBIX quarterly net margin is higher than 89.23% of companies in Healthcare sector
When is NBIX next earnings release?: The next earnings release for NBIX is on February 11, 2027

Net Margin Formula

Net Margin = Net Income

Revenue × 100%

Data Sources & References

NBIX Official Website www.neurocrine.com
Most Recent Annual Report (10-K) www.sec.gov/Archives/edgar/data/914475/000091447526000007/0000914475-26-000007-index.htm
NBIX Profile on Yahoo Finance finance.yahoo.com/quote/NBIX
NBIX Profile on NASDAQ.com www.nasdaq.com/market-activity/stocks/nbix