What is the current annual operating margin of RGEN?

As of today, RGEN annual operating margin is 8.07%

What is 1-year change in RGEN annual operating margin?

RGEN annual operating margin is up +126.05% year-over-year

What is 3-year change in RGEN annual operating margin?

RGEN annual operating margin is down -66.99% over the past 3 years

How far is RGEN annual operating margin from its all-time high?

RGEN annual operating margin is currently -76.05% below its historical high of 33.69% set on December 31, 2013

How does RGEN annual operating margin rank versus sector peers?

RGEN annual operating margin is higher than 76.54% of companies in Healthcare sector

When is RGEN next annual earnings release?

The next annual earnings release for RGEN is on February 23, 2027

What is the current quarterly operating margin of RGEN?

As of today, RGEN quarterly operating margin is 6.19%

What is RGEN quarterly operating margin most recent change?

RGEN quarterly operating margin was down -35.52% on September 30, 2026

What is 1-year change in RGEN quarterly operating margin?

RGEN quarterly operating margin is down -20.95% year-over-year

How far is RGEN quarterly operating margin from its all-time high?

RGEN quarterly operating margin is currently -99.85% below its historical high of 4,100.00% set on March 31, 1991

How does RGEN quarterly operating margin rank versus sector peers?

RGEN quarterly operating margin is higher than 69.44% of companies in Healthcare sector

When is RGEN next earnings release?

The next earnings release for RGEN is on February 23, 2027

RGEN Operating Margin History & Chart Since 1985

Annual Operating Margin

8.07%4.50%+126.05%

December 31, 2025

Summary

Current Value: As of today, RGEN annual operating margin is 8.07%, up +126.05% on December 31, 2025
Historical Performance: RGEN annual operating margin is down -66.99% over the past 3 years, down -63.63% over the past 5 years
All-Time High Comparison: RGEN annual operating margin is currently -76.05% below its historical high of 33.69% set on December 31, 2013
3-Year Low Comparison: RGEN annual operating margin is +126.05% above its 3-year low of 3.57% reached on December 31, 2024
Sector Comparison: RGEN annual operating margin is higher than 76.54% of companies in Healthcare sector

Operating Margin Chart

beforeafter

Performance

RGEN Performance
Metric	Date	Value	1Y	3Y	5Y	15Y
Annual Operating Margin	Dec 31, 25	8.07%	+126.0%	-67.0%	-63.6%	+1036.6%
Quarterly Operating Margin	Sep 30, 26	6.19%	-20.9%	+308.4%	-77.6%	-6.9%
Price	Oct 30, 26	$176.94	+22.4%	+55.0%	-39.1%	+5119.5%
PE Ratio	Oct 30, 26	-	–	–	–	–
Annual Revenue	Dec 31, 25	$738.26M	+16.4%	-7.9%	+101.6%	+2261.1%
Annual Operating Profit	Dec 31, 25	$59.58M	+163.1%	-69.6%	-26.7%	+10000.0%
Annual Gross Margin	Dec 31, 25	47.50%	+6.1%	-11.2%	-10.5%	-33.9%
Annual Net Margin	Dec 31, 25	6.62%	+264.7%	-71.5%	-59.5%	+196.2%

Operating Margin Highs

RGEN Annual Operating Margin Highs Comparison
Period	High	Date	Current
3Y	24.45%	N/A	-67.0%
5Y	28.82%	Dec 31, 21	-72.0%
All	33.69%	Dec 31, 13	-76.0%

Operating Margin Lows

RGEN Annual Operating Margin Lows Comparison
Period	Low	Date	Current
3Y	3.57%	Dec 31, 24	+126.0%
5Y	3.57%	Dec 31, 24	+126.0%
All	-325.16%	Mar 31, 01	+102.5%

Operating Margin History

Year	Value	Change
2025	8.07%	+126.1%
2024	3.57%	-54.2%
2023	7.80%	-68.1%
2022	24.45%	-15.2%
2021	28.82%	+29.9%
2020	22.19%	+49.6%
2019	14.83%	-0.4%
2018	14.89%	+45.7%
2017	10.22%	-50.1%
2016	20.50%	-4.0%
2015	21.36%	-0.0%
2014	21.37%	-36.6%
2013	33.69%	+94.9%
2012	17.29%	+2,335.2%
2011	0.71%	+102.6%
2010	-27.50%	-308.2%
2009	13.21%	+159.6%
2008	-22.17%	-70.9%
2007	-12.97%	-37.2%
2006	-9.45%	+78.7%
2005	-44.46%	+59.2%

Year	Value	Change
2004	-108.87%	-66.1%
2003	-65.55%	+49.4%
2002	-129.67%	+60.1%
2001	-325.16%	-150.2%
2000	-129.97%	-79.5%
1999	-72.40%	-53.2%
1998	-47.26%	-91.7%
1997	-24.65%	+83.2%
1996	-146.90%	-5.0%
1995	-139.86%	-72.8%
1994	-80.96%	-95.6%
1993	-41.39%	+62.2%
1992	-109.40%	-0.2%
1991	-109.21%	-454.6%
1990	-19.69%	+50.8%
1989	-40.00%	-271.1%
1988	-10.78%	+91.9%
1987	-132.43%	-90.7%
1986	-69.44%	+23.9%
1985	-91.30%	-

FAQ

What is the current annual operating margin of RGEN?: As of today, RGEN annual operating margin is 8.07%
What is 1-year change in RGEN annual operating margin?: RGEN annual operating margin is up +126.05% year-over-year
What is 3-year change in RGEN annual operating margin?: RGEN annual operating margin is down -66.99% over the past 3 years
How far is RGEN annual operating margin from its all-time high?: RGEN annual operating margin is currently -76.05% below its historical high of 33.69% set on December 31, 2013
How does RGEN annual operating margin rank versus sector peers?: RGEN annual operating margin is higher than 76.54% of companies in Healthcare sector
When is RGEN next annual earnings release?: The next annual earnings release for RGEN is on February 23, 2027

Operating Margin Formula

Operating Profit Margin = Operating Income

Revenue × 100%

Quarterly Operating Margin

6.19%3.41%-35.52%

September 30, 2026

Summary

Current Value: As of today, RGEN quarterly operating margin is 6.19%, down -35.52% on September 30, 2026
Historical Performance: RGEN quarterly operating margin is down -20.95% year-over-year, up +308.42% over the past 3 years
All-Time High Comparison: RGEN quarterly operating margin is currently -99.85% below its historical high of 4,100.00% set on March 31, 1991
3-Year Low Comparison: RGEN quarterly operating margin is +308.42% above its 3-year low of -2.97% reached on an earlier date
Sector Comparison: RGEN quarterly operating margin is higher than 69.44% of companies in Healthcare sector

Performance

RGEN Performance
Metric	Date	Value	3M	1Y	3Y	5Y
Quarterly Operating Margin	Sep 30, 26	6.19%	-35.5%	-20.9%	+308.4%	-77.6%
Annual Operating Margin	Dec 31, 25	8.07%	–	+126.0%	-67.0%	-63.6%
Price	Oct 30, 26	$176.94	+23.2%	+22.4%	+55.0%	-39.1%
PE Ratio	Oct 30, 26	-	–	–	–	–
Quarterly Revenue	Sep 30, 26	$209.31M	+2.5%	+10.9%	+48.3%	+17.4%
Quarterly Operating Profit	Sep 30, 26	$12.96M	-33.9%	-12.3%	+409.4%	-73.6%
Quarterly Gross Margin	Sep 30, 26	53.02%	+7.7%	+10.5%	+44.9%	-2.9%
Quarterly Net Margin	Sep 30, 26	-18.36%	-849.4%	-332.4%	-253.1%	-197.7%

Quarterly Operating Margin Highs

RGEN Quarterly Operating Margin Highs Comparison
Period	High	Date	Current
1Y	9.60%	Jun 30, 26	-35.5%
3Y	10.72%	Dec 31, 23	-42.3%
5Y	33.66%	Jun 30, 22	-81.6%
All	4,100.00%	Mar 31, 91	-99.8%

Quarterly Operating Margin Lows

RGEN Quarterly Operating Margin Lows Comparison
Period	Low	Date	Current
1Y	6.19%	Sep 30, 26	at low
3Y	-2.97%	N/A	+308.4%
5Y	-2.97%	Sep 30, 23	+308.4%
All	-633.33%	Mar 1, 85	+101.0%

Quarterly Operating Margin History

Month	Value	Change
Sep 2026	6.19%	-35.5%
Jun 2026	9.60%	+3.7%
Mar 2026	9.26%	-1.3%
Dec 2025	9.38%	+19.8%
Sep 2025	7.83%	+76.0%
Jun 2025	4.45%	-20.4%
Mar 2025	5.59%	-34.8%
Dec 2024	8.58%	+410.9%
Sep 2024	-2.76%	-159.0%
Jun 2024	4.68%	+5.9%
Mar 2024	4.42%	-58.8%
Dec 2023	10.72%	+460.9%
Sep 2023	-2.97%	-122.4%
Jun 2023	13.24%	+45.0%
Mar 2023	9.13%	-46.2%
Dec 2022	16.98%	-46.8%
Sep 2022	31.89%	-5.3%
Jun 2022	33.66%	+8.8%
Mar 2022	30.95%	+16.1%
Dec 2021	26.65%	-3.4%
Sep 2021	27.59%	-10.2%
Jun 2021	30.71%	+13.1%
Mar 2021	27.15%	+32.0%
Dec 2020	20.57%	-11.9%
Sep 2020	23.35%	+4.5%
Jun 2020	22.34%	+42.7%
Mar 2020	15.65%	+84.6%
Dec 2019	8.48%	-26.1%
Sep 2019	11.47%	-44.3%
Jun 2019	20.59%	+7.0%
Mar 2019	19.25%	+18.5%
Dec 2018	16.25%	-7.4%
Sep 2018	17.55%	+63.4%
Jun 2018	10.74%	-27.4%
Mar 2018	14.79%	+351.5%
Dec 2017	-5.88%	-172.4%
Sep 2017	8.12%	-51.8%
Jun 2017	16.86%	-37.7%
Mar 2017	27.05%	+83.9%
Dec 2016	14.71%	-17.9%
Sep 2016	17.92%	-19.5%
Jun 2016	22.27%	+2.2%
Mar 2016	21.79%	+37.6%
Dec 2015	15.84%	-20.0%
Sep 2015	19.79%	-21.0%
Jun 2015	25.06%	+1.3%
Mar 2015	24.75%	+102.2%
Dec 2014	12.24%	-16.0%
Sep 2014	14.57%	-27.5%
Jun 2014	20.09%	-39.3%
Mar 2014	33.11%	-2.6%
Dec 2013	33.99%	-21.1%
Sep 2013	43.07%	+22.8%
Jun 2013	35.06%	+65.3%
Mar 2013	21.21%	-37.8%
Dec 2012	34.08%	+135.4%
Sep 2012	14.48%	+70.6%
Jun 2012	8.49%	+27.7%
Mar 2012	6.65%	+118.8%
Mar 2011	-35.33%	-941.2%
Dec 2010	4.20%	-41.7%
Sep 2010	7.21%	-43.1%
Jun 2010	12.68%	+135.0%
Mar 2010	-36.18%	-48.3%
Dec 2009	-24.39%	-9.6%
Sep 2009	-22.26%	+21.1%
Jun 2009	-28.21%	+59.7%
Mar 2009	-70.00%	-683.0%
Dec 2008	-8.94%	-40.1%
Sep 2008	-6.38%	-111.0%
Jun 2008	58.26%	+149.8%
Mar 2008	-117.07%	-446.5%
Dec 2007	-21.42%	-291.1%
Sep 2007	11.21%	+4,584.0%
Jun 2007	-0.25%	+97.4%

Month	Value	Change
Mar 2007	-9.49%	-43.4%
Dec 2006	-6.62%	+82.7%
Sep 2006	-38.26%	-1,045.5%
Jun 2006	-3.34%	+90.5%
Mar 2006	-35.15%	-158.5%
Dec 2005	-13.60%	+44.0%
Sep 2005	-24.28%	-216.9%
Jun 2005	20.77%	+213.3%
Mar 2005	-18.33%	+60.6%
Dec 2004	-46.49%	+66.9%
Sep 2004	-140.39%	-431.8%
Jun 2004	-26.40%	+40.6%
Mar 2004	-44.47%	+73.6%
Dec 2003	-168.66%	-7.1%
Sep 2003	-157.43%	-52.6%
Jun 2003	-103.15%	-18.0%
Mar 2003	-87.45%	-133.2%
Dec 2002	-37.50%	+48.9%
Sep 2002	-73.38%	-2.5%
Jun 2002	-71.61%	+4.0%
Mar 2002	-74.57%	+18.3%
Dec 2001	-91.24%	+51.8%
Sep 2001	-189.31%	+20.1%
Jun 2001	-236.86%	+27.6%
Mar 2001	-327.27%	+4.4%
Dec 2000	-342.30%	+9.7%
Sep 2000	-378.92%	-68.8%
Jun 2000	-224.50%	-204.2%
Mar 2000	-73.81%	+71.0%
Dec 1999	-254.61%	-118.8%
Sep 1999	-116.37%	-59.2%
Jun 1999	-73.11%	+62.8%
Mar 1999	-196.77%	-255.8%
Dec 1998	-55.30%	-51.9%
Sep 1998	-36.41%	+45.9%
Jun 1998	-67.24%	-3.5%
Mar 1998	-64.96%	-419.7%
Dec 1997	-12.50%	+79.2%
Sep 1997	-60.00%	-319.9%
Jun 1997	-14.29%	-142.9%
Mar 1997	33.33%	+466.7%
Dec 1996	-9.09%	-145.5%
Sep 1996	20.00%	+132.0%
Jun 1996	-62.50%	+71.9%
Mar 1996	-222.22%	-102.9%
Dec 1995	-109.52%	-447.6%
Sep 1995	-20.00%	+78.5%
Jun 1995	-92.86%	-69.1%
Mar 1995	-54.90%	+65.3%
Dec 1994	-158.33%	+8.8%
Sep 1994	-173.53%	-41.2%
Jun 1994	-122.92%	-73.7%
Mar 1994	-70.77%	+10.5%
Dec 1993	-79.10%	-16.9%
Sep 1993	-67.65%	+17.8%
Jun 1993	-82.26%	-3,932.4%
Mar 1993	-2.04%	+98.5%
Dec 1992	-134.88%	-49.2%
Sep 1992	-90.38%	-2,112.9%
Jun 1992	4.49%	+126.4%
Mar 1992	-17.02%	+95.3%
Dec 1991	-365.22%	-232.0%
Sep 1991	-110.00%	-112.2%
Jun 1991	-51.85%	-101.3%
Mar 1991	4,100.00%	+6,933.3%
Dec 1990	-60.00%	-7.1%
Sep 1990	-56.00%	-12.0%
Jun 1990	-50.00%	+80.3%
Mar 1990	-253.49%	+42.5%
Mar 1989	-440.91%	-59.4%
Mar 1988	-276.67%	+55.1%
Mar 1987	-616.67%	-6.7%
Mar 1986	-577.78%	+8.8%
Mar 1985	-633.33%	-

FAQ

What is the current quarterly operating margin of RGEN?: As of today, RGEN quarterly operating margin is 6.19%
What is RGEN quarterly operating margin most recent change?: RGEN quarterly operating margin was down -35.52% on September 30, 2026
What is 1-year change in RGEN quarterly operating margin?: RGEN quarterly operating margin is down -20.95% year-over-year
How far is RGEN quarterly operating margin from its all-time high?: RGEN quarterly operating margin is currently -99.85% below its historical high of 4,100.00% set on March 31, 1991
How does RGEN quarterly operating margin rank versus sector peers?: RGEN quarterly operating margin is higher than 69.44% of companies in Healthcare sector
When is RGEN next earnings release?: The next earnings release for RGEN is on February 23, 2027

Operating Margin Formula

Operating Profit Margin = Operating Income

Revenue × 100%

Data Sources & References

RGEN Official Website www.repligen.com
Most Recent Annual Report (10-K) www.sec.gov/Archives/edgar/data/730272/000119312526076528/0001193125-26-076528-index.htm
RGEN Profile on Yahoo Finance finance.yahoo.com/quote/RGEN
RGEN Profile on NASDAQ.com www.nasdaq.com/market-activity/stocks/rgen