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Ionis Pharmaceuticals, Inc. (IONS) return on equity

annual ROE:

-93.10%-16.76%(-21.95%)
December 31, 2024

Summary

  • As of today (August 19, 2025), IONS annual return on equity is -93.10%, with the most recent change of -16.76% (-21.95%) on December 31, 2024.
  • During the last 3 years, IONS annual ROE has fallen by -89.32% (-2362.96%).
  • IONS annual ROE is now -147.12% below its all-time high of 197.56%, reached on December 31, 2004.

Performance

IONS ROE Chart

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Highlights

Range

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quarterly ROE:

-51.08%+48.99%(+48.96%)
June 30, 2025

Summary

  • As of today (August 19, 2025), IONS quarterly return on equity is -51.08%, with the most recent change of +48.99% (+48.96%) on June 30, 2025.
  • Over the past year, IONS quarterly ROE has increased by +57.01% (+52.74%).
  • IONS quarterly ROE is now -103.62% below its all-time high of 1410.79%, reached on June 30, 1999.

Performance

IONS quarterly ROE Chart

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ROE Formula

ROE =  Net Income
Shareholders Equity
✕ 100%

IONS ROE Trends

PeriodPeriodAnnualAnnualQuarterlyQuarterly
1 y1 year-21.9%+52.7%
3 y3 years-2363.0%-1071.6%
5 y5 years-537.3%-693.3%

IONS ROE Highs & Lows

PeriodPeriodAnnual vs highAnnual vs highAnnual vs lowAnnual vs lowQuarter. vs highQuarter. vs highQuarter. vs lowQuarter. vs low
3 y3-year-2363.0%at low-4541.7%+52.7%
5 y5-year-537.3%at low-693.3%+52.7%
alltimeall time-147.1%+98.6%-103.6%+98.8%

IONS ROE History

DateAnnualQuarterly
Jun 2025
-
-51.08%(-49.0%)
Mar 2025
-
-100.07%(-3.0%)
Dec 2024
-93.10%(+22.0%)
-103.19%(+10.8%)
Sep 2024
-
-93.14%(-13.8%)
Jun 2024
-
-108.09%(+7.6%)
Mar 2024
-
-100.47%(+20.2%)
Dec 2023
-76.34%(+90.3%)
-83.57%(-2.0%)
Sep 2023
-
-85.30%(+49.6%)
Jun 2023
-
-57.00%(+3.7%)
Mar 2023
-
-54.96%(+33.6%)
Dec 2022
-40.12%(+961.4%)
-41.13%(-3676.5%)
Sep 2022
-
1.15%(-126.4%)
Jun 2022
-
-4.36%(+651.7%)
Mar 2022
-
-0.58%(-86.5%)
Dec 2021
-3.78%(-90.4%)
-4.31%(-94.1%)
Sep 2021
-
-73.52%(+35.9%)
Jun 2021
-
-54.09%(+28.9%)
Mar 2021
-
-41.97%(+25.9%)
Dec 2020
-39.52%(-285.6%)
-33.34%(-769.5%)
Sep 2020
-
4.98%(-42.2%)
Jun 2020
-
8.61%(-19.2%)
Mar 2020
-
10.65%(-49.7%)
Dec 2019
21.29%(-24.2%)
21.19%(-33.3%)
Sep 2019
-
31.79%(-1.2%)
Jun 2019
-
32.19%(-7.0%)
Mar 2019
-
34.61%(+15.8%)
Dec 2018
28.10%(+751.5%)
29.88%(-283.3%)
Sep 2018
-
-16.30%(-9.5%)
Jun 2018
-
-18.01%(+124.3%)
Mar 2018
-
-8.03%(+280.6%)
Dec 2017
3.30%(-105.7%)
-2.11%(-118.3%)
Sep 2017
-
11.50%(-54.8%)
Jun 2017
-
25.46%(-346.5%)
Mar 2017
-
-10.33%(-83.1%)
Dec 2016
-57.64%(+49.7%)
-61.01%(-43.2%)
Sep 2016
-
-107.49%(-3.8%)
Jun 2016
-
-111.71%(+96.1%)
Mar 2016
-
-56.96%(+65.2%)
Dec 2015
-38.50%(+214.0%)
-34.48%(-791.0%)
Sep 2015
-
4.99%(-33.8%)
Jun 2015
-
7.54%(-200.0%)
Mar 2015
-
-7.54%(-33.4%)
Dec 2014
-12.26%(-43.3%)
-11.32%(-55.2%)
Sep 2014
-
-25.28%(+5.4%)
Jun 2014
-
-23.99%(-6.7%)
Mar 2014
-
-25.70%(+32.6%)
Dec 2013
-21.61%(-41.5%)
-19.38%(+34.8%)
Sep 2013
-
-14.38%(-38.7%)
Jun 2013
-
-23.47%(-6.5%)
Mar 2013
-
-25.11%(-36.4%)
Dec 2012
-36.97%(-9.3%)
-39.46%(-20.6%)
Sep 2012
-
-49.70%(+20.7%)
Jun 2012
-
-41.18%(-12.0%)
Mar 2012
-
-46.78%(+15.1%)
Dec 2011
-40.77%(+81.9%)
-40.66%(+16.2%)
Sep 2011
-
-35.00%(+30.6%)
Jun 2011
-
-26.79%(-4.8%)
Mar 2011
-
-28.13%(+23.7%)
Dec 2010
-22.41%(+30.2%)
-22.74%(-0.1%)
Sep 2010
-
-22.77%(+15.7%)
Jun 2010
-
-19.68%(+72.0%)
Mar 2010
-
-11.44%(-120.4%)
Dec 2009
-17.21%(+18.5%)
56.12%(-27.3%)
Sep 2009
-
77.15%(-21.6%)
Jun 2009
-
98.38%(-24.0%)
Mar 2009
-
129.43%(+8826.2%)
Dec 2008
-14.52%
1.45%(-100.6%)
Sep 2008
-
-229.44%(-8.7%)
Jun 2008
-
-251.41%(-17.2%)
DateAnnualQuarterly
Mar 2008
-
-303.78%(-1.3%)
Dec 2007
-64.32%(-53.1%)
-307.90%(+350.3%)
Sep 2007
-
-68.38%(-21.2%)
Jun 2007
-
-86.77%(-17.9%)
Mar 2007
-
-105.63%(-27.7%)
Dec 2006
-137.07%(-95.0%)
-146.08%(-51.3%)
Sep 2006
-
-299.84%(-93.0%)
Jun 2006
-
-4278.21%(-2331.3%)
Mar 2006
-
191.74%(+46.7%)
Dec 2005
-2716.74%(-1475.1%)
130.67%(-20.6%)
Sep 2005
-
164.66%(-6.2%)
Jun 2005
-
175.49%(-45.2%)
Mar 2005
-
320.01%(-116.4%)
Dec 2004
197.56%(-331.5%)
-1948.31%(+614.1%)
Sep 2004
-
-272.82%(+81.8%)
Jun 2004
-
-150.04%(+40.9%)
Mar 2004
-
-106.49%(+26.3%)
Dec 2003
-85.33%(+123.6%)
-84.33%(+31.6%)
Sep 2003
-
-64.09%(+20.4%)
Jun 2003
-
-53.21%(+15.0%)
Mar 2003
-
-46.25%(+20.2%)
Dec 2002
-38.17%(-25.2%)
-38.49%(-3.7%)
Sep 2002
-
-39.98%(-7.0%)
Jun 2002
-
-43.01%(-20.9%)
Mar 2002
-
-54.35%(-26.7%)
Dec 2001
-51.01%(-67.9%)
-74.14%(-31.4%)
Sep 2001
-
-108.07%(-5.3%)
Jun 2001
-
-114.10%(+15.8%)
Mar 2001
-
-98.50%(-7.6%)
Dec 2000
-159.10%(-97.7%)
-106.61%(-32.9%)
Sep 2000
-
-159.00%(-47.3%)
Jun 2000
-
-301.59%(-82.8%)
Mar 2000
-
-1752.32%(-317.1%)
Dec 1999
-6815.30%(+2331.2%)
807.02%(+19.3%)
Sep 1999
-
676.66%(-52.0%)
Jun 1999
-
1410.79%(-287.6%)
Mar 1999
-
-751.93%(+96.8%)
Dec 1998
-280.33%(+320.7%)
-382.04%(+157.8%)
Sep 1998
-
-148.21%(+20.1%)
Jun 1998
-
-123.39%(+40.7%)
Mar 1998
-
-87.67%(+28.4%)
Dec 1997
-66.64%(+68.7%)
-68.29%(+22.0%)
Sep 1997
-
-55.97%(-3.3%)
Jun 1997
-
-57.90%(+18.4%)
Mar 1997
-
-48.91%(+22.4%)
Dec 1996
-39.51%(+1.5%)
-39.96%(+11.2%)
Sep 1996
-
-35.95%(-10.2%)
Jun 1996
-
-40.03%(-2.7%)
Mar 1996
-
-41.14%(-12.2%)
Dec 1995
-38.91%(+11.8%)
-46.85%(-12.8%)
Sep 1995
-
-53.70%(+8.2%)
Jun 1995
-
-49.64%(+14.7%)
Mar 1995
-
-43.28%(+31.6%)
Dec 1994
-34.80%(-10.3%)
-32.88%(+7.5%)
Sep 1994
-
-30.60%(+3.6%)
Jun 1994
-
-29.54%(+0.2%)
Mar 1994
-
-29.47%(-25.0%)
Dec 1993
-38.78%(-1.6%)
-39.28%(-8.9%)
Sep 1993
-
-43.10%(+1.2%)
Jun 1993
-
-42.60%(+5.1%)
Mar 1993
-
-40.53%(+3.1%)
Dec 1992
-39.42%(+37.7%)
-39.31%(+8.1%)
Sep 1992
-
-36.36%(+11.1%)
Jun 1992
-
-32.72%(-1.0%)
Mar 1992
-
-33.05%(+5.0%)
Dec 1991
-28.62%(-89.2%)
-31.48%(-5.7%)
Sep 1991
-
-33.38%(+0.8%)
Jun 1991
-
-33.13%(-45.4%)
Mar 1991
-
-60.69%(-76.6%)
Dec 1990
-264.71%
-258.82%

FAQ

  • What is Ionis Pharmaceuticals, Inc. annual return on equity?
  • What is the all time high annual ROE for Ionis Pharmaceuticals, Inc.?
  • What is Ionis Pharmaceuticals, Inc. annual ROE year-on-year change?
  • What is Ionis Pharmaceuticals, Inc. quarterly return on equity?
  • What is the all time high quarterly ROE for Ionis Pharmaceuticals, Inc.?
  • What is Ionis Pharmaceuticals, Inc. quarterly ROE year-on-year change?

What is Ionis Pharmaceuticals, Inc. annual return on equity?

The current annual ROE of IONS is -93.10%

What is the all time high annual ROE for Ionis Pharmaceuticals, Inc.?

Ionis Pharmaceuticals, Inc. all-time high annual return on equity is 197.56%

What is Ionis Pharmaceuticals, Inc. annual ROE year-on-year change?

Over the past year, IONS annual return on equity has changed by -16.76% (-21.95%)

What is Ionis Pharmaceuticals, Inc. quarterly return on equity?

The current quarterly ROE of IONS is -51.08%

What is the all time high quarterly ROE for Ionis Pharmaceuticals, Inc.?

Ionis Pharmaceuticals, Inc. all-time high quarterly return on equity is 1410.79%

What is Ionis Pharmaceuticals, Inc. quarterly ROE year-on-year change?

Over the past year, IONS quarterly return on equity has changed by +57.01% (+52.74%)
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