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Denali Therapeutics Inc. (DNLI) Operating Profit

Annual Operating Profit:

-$501.88M-$305.18M(-155.15%)
December 31, 2024

Summary

  • As of today, DNLI annual operating income is -$501.88 million, with the most recent change of -$305.18 million (-155.15%) on December 31, 2024.
  • During the last 3 years, DNLI annual operating profit has fallen by -$206.13 million (-69.70%).
  • DNLI annual operating profit is now -900.21% below its all-time high of $62.72 million, reached on December 31, 2020.

Performance

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Quarterly Operating Profit:

-$134.96M+$10.62M(+7.29%)
June 30, 2025

Summary

  • As of today, DNLI quarterly operating income is -$134.96 million, with the most recent change of +$10.62 million (+7.29%) on June 30, 2025.
  • Over the past year, DNLI quarterly operating profit has dropped by -$18.37 million (-15.76%).
  • DNLI quarterly operating profit is now -155.30% below its all-time high of $244.08 million, reached on December 31, 2020.

Performance

DNLI Quarterly Operating Profit Chart

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TTM Operating Profit:

-$533.58M-$18.37M(-3.57%)
June 30, 2025

Summary

  • As of today, DNLI TTM operating income is -$533.58 million, with the most recent change of -$18.37 million (-3.57%) on June 30, 2025.
  • Over the past year, DNLI TTM operating profit has dropped by -$38.36 million (-7.75%).
  • DNLI TTM operating profit is now -950.75% below its all-time high of $62.72 million, reached on December 31, 2020.

Performance

DNLI TTM Operating Profit Chart

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Operating Profit Formula

Operating Profit = Gross Profit − Operating Expenses

DNLI Operating Profit Trends

PeriodPeriodAnnualAnnualQuarterlyQuarterlyTTMTTM
1Y1 Year-155.2%-15.8%-7.8%
3Y3 Years-69.7%-119.8%-83.6%
5Y5 Years-135.4%-120.3%-123.1%

DNLI Operating Profit Highs & Lows

PeriodPeriodAnnual vs HighAnnual vs HighAnnual vs LowAnnual vs LowQuarter. vs HighQuarter. vs HighQuarter. vs LowQuarter. vs LowTTM vs HighTTM vs HighTTM vs LowTTM vs Low
3Y3-Year-155.2%at low-179.2%+7.3%-227.0%at low
5Y5-Year-900.2%at low-155.3%+7.3%-950.8%at low
All-TimeAll-Time-900.2%at low-155.3%+7.3%-950.8%at low

DNLI Operating Profit History

DateAnnualQuarterlyTTM
Jun 2025
-
-$134.96M(+7.3%)
-$533.58M(-3.6%)
Mar 2025
-
-$145.58M(-12.1%)
-$515.21M(-2.7%)
Dec 2024
-$501.88M(-155.2%)
-$129.85M(-5.4%)
-$501.88M(+0.5%)
Sep 2024
-
-$123.19M(-5.7%)
-$504.60M(-1.9%)
Jun 2024
-
-$116.59M(+11.8%)
-$495.21M(-137.9%)
Mar 2024
-
-$132.25M(+0.2%)
-$208.14M(-5.8%)
Dec 2023
-$196.70M(+42.3%)
-$132.57M(-16.5%)
-$196.70M(-16.1%)
Sep 2023
-
-$113.80M(-166.7%)
-$169.47M(-3.9%)
Jun 2023
-
$170.48M(+241.1%)
-$163.16M(+58.7%)
Mar 2023
-
-$120.81M(-14.7%)
-$395.06M(-15.9%)
Dec 2022
-$340.74M(-15.2%)
-$105.34M(+2.0%)
-$340.74M(-9.0%)
Sep 2022
-
-$107.49M(-75.0%)
-$312.52M(-7.5%)
Jun 2022
-
-$61.42M(+7.6%)
-$290.63M(+0.1%)
Mar 2022
-
-$66.50M(+13.8%)
-$291.03M(+1.6%)
Dec 2021
-$295.75M(-571.6%)
-$77.12M(+9.9%)
-$295.75M(-1262.2%)
Sep 2021
-
-$85.59M(-38.5%)
$25.45M(-50.0%)
Jun 2021
-
-$61.82M(+13.2%)
$50.92M(-1.0%)
Mar 2021
-
-$71.22M(-129.2%)
$51.47M(-17.9%)
DateAnnualQuarterlyTTM
Dec 2020
$62.72M(+129.4%)
$244.08M(+506.0%)
$62.72M(+126.2%)
Sep 2020
-
-$60.12M(+1.9%)
-$239.12M(-4.3%)
Jun 2020
-
-$61.28M(-2.2%)
-$229.16M(-0.1%)
Mar 2020
-
-$59.97M(-3.8%)
-$228.84M(-8.3%)
Dec 2019
-$213.18M(-359.7%)
-$57.76M(-15.2%)
-$211.38M(-167.9%)
Sep 2019
-
-$50.16M(+17.7%)
-$78.90M(-18.3%)
Jun 2019
-
-$60.96M(-43.4%)
-$66.71M(-20.8%)
Mar 2019
-
-$42.51M(-156.9%)
-$55.23M(-43.6%)
Dec 2018
-$46.37M(+48.6%)
$74.72M(+296.8%)
-$38.47M(+71.9%)
Sep 2018
-
-$37.96M(+23.3%)
-$136.73M(-12.9%)
Jun 2018
-
-$49.48M(-92.2%)
-$121.06M(-28.6%)
Mar 2018
-
-$25.75M(-9.4%)
-$94.14M(-4.4%)
Dec 2017
-$90.14M(-3.1%)
-$23.54M(-5.6%)
-$90.14M(-4.4%)
Sep 2017
-
-$22.29M(+1.2%)
-$86.38M(+9.1%)
Jun 2017
-
-$22.57M(-3.8%)
-$95.02M(-31.1%)
Mar 2017
-
-$21.74M(-10.0%)
-$72.45M(-42.9%)
Dec 2016
-$87.43M(-424.2%)
-$19.78M(+36.1%)
-$50.71M(-63.9%)
Sep 2016
-
-$30.93M
-$30.93M
Dec 2015
-$16.68M
-
-

FAQ

  • What is Denali Therapeutics Inc. annual operating income?
  • What is the all-time high annual operating profit for Denali Therapeutics Inc.?
  • What is Denali Therapeutics Inc. annual operating profit year-on-year change?
  • What is Denali Therapeutics Inc. quarterly operating income?
  • What is the all-time high quarterly operating profit for Denali Therapeutics Inc.?
  • What is Denali Therapeutics Inc. quarterly operating profit year-on-year change?
  • What is Denali Therapeutics Inc. TTM operating income?
  • What is the all-time high TTM operating profit for Denali Therapeutics Inc.?
  • What is Denali Therapeutics Inc. TTM operating profit year-on-year change?

What is Denali Therapeutics Inc. annual operating income?

The current annual operating profit of DNLI is -$501.88M

What is the all-time high annual operating profit for Denali Therapeutics Inc.?

Denali Therapeutics Inc. all-time high annual operating income is $62.72M

What is Denali Therapeutics Inc. annual operating profit year-on-year change?

Over the past year, DNLI annual operating income has changed by -$305.18M (-155.15%)

What is Denali Therapeutics Inc. quarterly operating income?

The current quarterly operating profit of DNLI is -$134.96M

What is the all-time high quarterly operating profit for Denali Therapeutics Inc.?

Denali Therapeutics Inc. all-time high quarterly operating income is $244.08M

What is Denali Therapeutics Inc. quarterly operating profit year-on-year change?

Over the past year, DNLI quarterly operating income has changed by -$18.37M (-15.76%)

What is Denali Therapeutics Inc. TTM operating income?

The current TTM operating profit of DNLI is -$533.58M

What is the all-time high TTM operating profit for Denali Therapeutics Inc.?

Denali Therapeutics Inc. all-time high TTM operating income is $62.72M

What is Denali Therapeutics Inc. TTM operating profit year-on-year change?

Over the past year, DNLI TTM operating income has changed by -$38.36M (-7.75%)
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