annual operating profit:
-$501.88M-$305.18M(-155.15%)Summary
- As of today (September 10, 2025), DNLI annual operating income is -$501.88 million, with the most recent change of -$305.18 million (-155.15%) on December 31, 2024.
- During the last 3 years, DNLI annual operating profit has fallen by -$206.13 million (-69.70%).
- DNLI annual operating profit is now -900.21% below its all-time high of $62.72 million, reached on December 31, 2020.
Performance
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quarterly operating profit:
-$134.96M+$10.62M(+7.29%)Summary
- As of today (September 10, 2025), DNLI quarterly operating income is -$134.96 million, with the most recent change of +$10.62 million (+7.29%) on June 30, 2025.
- Over the past year, DNLI quarterly operating profit has dropped by -$18.37 million (-15.76%).
- DNLI quarterly operating profit is now -155.30% below its all-time high of $244.08 million, reached on December 31, 2020.
Performance
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TTM operating profit:
-$533.58M-$18.37M(-3.57%)Summary
- As of today (September 10, 2025), DNLI TTM operating income is -$533.58 million, with the most recent change of -$18.37 million (-3.57%) on June 30, 2025.
- Over the past year, DNLI TTM operating profit has dropped by -$38.36 million (-7.75%).
- DNLI TTM operating profit is now -950.75% below its all-time high of $62.72 million, reached on December 31, 2020.
Performance
DNLI TTM operating profit Chart
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Operating profit Formula
Operating Profit = Gross Profit − Operating Expenses
DNLI Operating profit Trends
| PeriodPeriod | AnnualAnnual | QuarterlyQuarterly | TTMTTM |
|---|---|---|---|
| 1 y1 year | -155.2% | -15.8% | -7.8% |
| 3 y3 years | -69.7% | -119.8% | -83.6% |
| 5 y5 years | -135.4% | -120.3% | -132.8% |
DNLI Operating profit Highs & Lows
| PeriodPeriod | Annual vs highAnnual vs high | Annual vs lowAnnual vs low | Quarter. vs highQuarter. vs high | Quarter. vs lowQuarter. vs low | TTM vs highTTM vs high | TTM vs lowTTM vs low | |
|---|---|---|---|---|---|---|---|
| 3 y | 3-year | -155.2% | at low | -179.2% | +7.3% | -227.0% | at low |
| 5 y | 5-year | -900.2% | at low | -155.3% | +7.3% | -950.8% | at low |
| alltime | all time | -900.2% | at low | -155.3% | +7.3% | -950.8% | at low |
DNLI Operating profit History
| Date | Annual | Quarterly | TTM |
|---|---|---|---|
| Jun 2025 | - | -$134.96M(-7.3%) | -$533.58M(+3.6%) |
| Mar 2025 | - | -$145.58M(+12.1%) | -$515.21M(+2.7%) |
| Dec 2024 | -$501.88M(+155.2%) | -$129.85M(+5.4%) | -$501.88M(-0.5%) |
| Sep 2024 | - | -$123.19M(+5.7%) | -$504.60M(+1.9%) |
| Jun 2024 | - | -$116.59M(-11.8%) | -$495.21M(+137.9%) |
| Mar 2024 | - | -$132.25M(-0.2%) | -$208.14M(+5.8%) |
| Dec 2023 | -$196.70M(-42.3%) | -$132.57M(+16.5%) | -$196.70M(+16.1%) |
| Sep 2023 | - | -$113.80M(-166.7%) | -$169.47M(+3.9%) |
| Jun 2023 | - | $170.48M(-241.1%) | -$163.16M(-58.7%) |
| Mar 2023 | - | -$120.81M(+14.7%) | -$395.06M(+15.9%) |
| Dec 2022 | -$340.74M(+15.2%) | -$105.34M(-2.0%) | -$340.74M(+9.0%) |
| Sep 2022 | - | -$107.49M(+75.0%) | -$312.52M(+7.5%) |
| Jun 2022 | - | -$61.42M(-7.6%) | -$290.63M(-0.1%) |
| Mar 2022 | - | -$66.50M(-13.8%) | -$291.03M(-1.6%) |
| Dec 2021 | -$295.75M(-571.6%) | -$77.12M(-9.9%) | -$295.75M(-1262.2%) |
| Sep 2021 | - | -$85.59M(+38.5%) | $25.45M(-50.0%) |
| Jun 2021 | - | -$61.82M(-13.2%) | $50.92M(-1.0%) |
| Mar 2021 | - | -$71.22M(-129.2%) | $51.47M(-17.9%) |
| Date | Annual | Quarterly | TTM |
|---|---|---|---|
| Dec 2020 | $62.72M(-129.4%) | $244.08M(-506.0%) | $62.72M(-126.2%) |
| Sep 2020 | - | -$60.12M(-1.9%) | -$239.12M(+4.3%) |
| Jun 2020 | - | -$61.28M(+2.2%) | -$229.16M(+0.1%) |
| Mar 2020 | - | -$59.97M(+3.8%) | -$228.84M(+8.3%) |
| Dec 2019 | -$213.18M(+359.7%) | -$57.76M(+15.2%) | -$211.38M(+167.9%) |
| Sep 2019 | - | -$50.16M(-17.7%) | -$78.90M(+18.3%) |
| Jun 2019 | - | -$60.96M(+43.4%) | -$66.71M(+20.8%) |
| Mar 2019 | - | -$42.51M(-156.9%) | -$55.23M(+43.6%) |
| Dec 2018 | -$46.37M(-48.6%) | $74.72M(-296.8%) | -$38.47M(-71.9%) |
| Sep 2018 | - | -$37.96M(-23.3%) | -$136.73M(+12.9%) |
| Jun 2018 | - | -$49.48M(+92.2%) | -$121.06M(+28.6%) |
| Mar 2018 | - | -$25.75M(+9.4%) | -$94.14M(+4.4%) |
| Dec 2017 | -$90.14M(+3.1%) | -$23.54M(+5.6%) | -$90.14M(+4.4%) |
| Sep 2017 | - | -$22.29M(-1.2%) | -$86.38M(-9.1%) |
| Jun 2017 | - | -$22.57M(+3.8%) | -$95.02M(+31.1%) |
| Mar 2017 | - | -$21.74M(+10.0%) | -$72.45M(+42.9%) |
| Dec 2016 | -$87.43M(+424.2%) | -$19.78M(-36.1%) | -$50.71M(+63.9%) |
| Sep 2016 | - | -$30.93M | -$30.93M |
| Dec 2015 | -$16.68M | - | - |
FAQ
- What is Denali Therapeutics Inc. annual operating income?
- What is the all time high annual operating profit for Denali Therapeutics Inc.?
- What is Denali Therapeutics Inc. annual operating profit year-on-year change?
- What is Denali Therapeutics Inc. quarterly operating income?
- What is the all time high quarterly operating profit for Denali Therapeutics Inc.?
- What is Denali Therapeutics Inc. quarterly operating profit year-on-year change?
- What is Denali Therapeutics Inc. TTM operating income?
- What is the all time high TTM operating profit for Denali Therapeutics Inc.?
- What is Denali Therapeutics Inc. TTM operating profit year-on-year change?
What is Denali Therapeutics Inc. annual operating income?
The current annual operating profit of DNLI is -$501.88M
What is the all time high annual operating profit for Denali Therapeutics Inc.?
Denali Therapeutics Inc. all-time high annual operating income is $62.72M
What is Denali Therapeutics Inc. annual operating profit year-on-year change?
Over the past year, DNLI annual operating income has changed by -$305.18M (-155.15%)
What is Denali Therapeutics Inc. quarterly operating income?
The current quarterly operating profit of DNLI is -$134.96M
What is the all time high quarterly operating profit for Denali Therapeutics Inc.?
Denali Therapeutics Inc. all-time high quarterly operating income is $244.08M
What is Denali Therapeutics Inc. quarterly operating profit year-on-year change?
Over the past year, DNLI quarterly operating income has changed by -$18.37M (-15.76%)
What is Denali Therapeutics Inc. TTM operating income?
The current TTM operating profit of DNLI is -$533.58M
What is the all time high TTM operating profit for Denali Therapeutics Inc.?
Denali Therapeutics Inc. all-time high TTM operating income is $62.72M
What is Denali Therapeutics Inc. TTM operating profit year-on-year change?
Over the past year, DNLI TTM operating income has changed by -$38.36M (-7.75%)