Annual Operating Profit:
-$176.88M+$105.29M(+37.31%)Summary
- As of today, ALNY annual operating income is -$176.88 million, with the most recent change of +$105.29 million (+37.31%) on December 31, 2024.
- During the last 3 years, ALNY annual operating profit has risen by +$531.77 million (+75.04%).
- ALNY annual operating profit is now -4089.60% below its all-time high of -$4.22 million, reached on December 31, 2002.
Performance
ALNY Operating Profit Chart
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Quarterly Operating Profit:
$367.98M+$384.18M(+2371.63%)Summary
- As of today, ALNY quarterly operating income is $367.98 million, with the most recent change of +$384.18 million (+2371.63%) on September 30, 2025.
- Over the past year, ALNY quarterly operating profit has increased by +$444.89 million (+578.49%).
- ALNY quarterly operating profit is now at all-time high.
Performance
ALNY Quarterly Operating Profit Chart
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TTM Operating Profit:
$264.70M+$444.89M(+246.90%)Summary
- As of today, ALNY TTM operating income is $264.70 million, with the most recent change of +$444.89 million (+246.90%) on September 30, 2025.
- Over the past year, ALNY TTM operating profit has increased by +$452.83 million (+240.70%).
- ALNY TTM operating profit is now at all-time high.
Performance
ALNY TTM Operating Profit Chart
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Operating Profit Formula
Operating Profit = Gross Profit − Operating Expenses
ALNY Operating Profit Trends
| PeriodPeriod | AnnualAnnual | QuarterlyQuarterly | TTMTTM |
|---|---|---|---|
| 1Y1 Year | +37.3% | +578.5% | +240.7% |
| 3Y3 Years | +75.0% | +242.6% | +133.5% |
| 5Y5 Years | +81.2% | +263.4% | +128.4% |
ALNY Operating Profit Highs & Lows
| PeriodPeriod | Annual vs HighAnnual vs High | Annual vs LowAnnual vs Low | Quarter. vs HighQuarter. vs High | Quarter. vs LowQuarter. vs Low | TTM vs HighTTM vs High | TTM vs LowTTM vs Low | |
|---|---|---|---|---|---|---|---|
| 3Y | 3-Year | at high | +77.5% | at high | +242.6% | at high | +132.0% |
| 5Y | 5-Year | at high | +81.2% | at high | +242.6% | at high | +128.4% |
| All-Time | All-Time | -4089.6% | +81.2% | at high | +223.4% | at high | +127.5% |
ALNY Operating Profit History
| Date | Annual | Quarterly | TTM |
|---|---|---|---|
| Sep 2025 | - | $367.98M(+2371.6%) | $264.70M(+246.9%) |
| Jun 2025 | - | -$16.20M(-189.6%) | -$180.19M(-56.2%) |
| Mar 2025 | - | $18.08M(+117.2%) | -$115.37M(+34.8%) |
| Dec 2024 | -$176.88M(+37.3%) | -$105.16M(-36.7%) | -$176.88M(+6.0%) |
| Sep 2024 | - | -$76.91M(-258.2%) | -$188.13M(-283.3%) |
| Jun 2024 | - | $48.61M(+211.9%) | $102.64M(+158.4%) |
| Mar 2024 | - | -$43.44M(+62.7%) | -$175.80M(+37.7%) |
| Dec 2023 | -$282.18M(+64.1%) | -$116.40M(-154.4%) | -$282.18M(+20.4%) |
| Sep 2023 | - | $213.87M(+193.1%) | -$354.38M(+57.1%) |
| Jun 2023 | - | -$229.83M(-53.4%) | -$826.29M(-4.8%) |
| Mar 2023 | - | -$149.81M(+20.6%) | -$788.15M(-0.4%) |
| Dec 2022 | -$785.07M(-10.8%) | -$188.61M(+26.9%) | -$785.07M(+0.8%) |
| Sep 2022 | - | -$258.04M(-34.6%) | -$791.02M(-10.7%) |
| Jun 2022 | - | -$191.69M(-30.6%) | -$714.66M(-6.8%) |
| Mar 2022 | - | -$146.73M(+24.6%) | -$669.13M(+5.6%) |
| Dec 2021 | -$708.65M(+14.5%) | -$194.56M(-7.1%) | -$708.65M(-0.0%) |
| Sep 2021 | - | -$181.68M(-24.3%) | -$708.31M(+5.8%) |
| Jun 2021 | - | -$146.16M(+21.5%) | -$751.84M(+6.6%) |
| Mar 2021 | - | -$186.25M(+4.1%) | -$804.53M(+2.9%) |
| Dec 2020 | -$828.44M(+11.8%) | -$194.22M(+13.8%) | -$828.44M(+11.1%) |
| Sep 2020 | - | -$225.20M(-13.2%) | -$932.29M(-1.0%) |
| Jun 2020 | - | -$198.86M(+5.4%) | -$923.39M(+3.9%) |
| Mar 2020 | - | -$210.16M(+29.5%) | -$960.80M(-2.3%) |
| Dec 2019 | -$939.43M(-15.3%) | -$298.07M(-37.8%) | -$939.43M(-9.0%) |
| Sep 2019 | - | -$216.30M(+8.5%) | -$861.71M(+4.3%) |
| Jun 2019 | - | -$236.27M(-25.2%) | -$899.97M(-5.1%) |
| Mar 2019 | - | -$188.79M(+14.3%) | -$856.06M(-5.1%) |
| Dec 2018 | -$814.67M(-62.9%) | -$220.36M(+13.4%) | -$814.67M(-9.9%) |
| Sep 2018 | - | -$254.56M(-32.3%) | -$741.62M(-21.0%) |
| Jun 2018 | - | -$192.35M(-30.5%) | -$612.86M(-13.3%) |
| Mar 2018 | - | -$147.41M(-0.1%) | -$540.98M(-8.2%) |
| Dec 2017 | -$500.09M(-17.8%) | -$147.30M(-17.1%) | -$500.09M(-6.8%) |
| Sep 2017 | - | -$125.80M(-4.4%) | -$468.22M(-4.3%) |
| Jun 2017 | - | -$120.47M(-13.1%) | -$449.09M(-6.7%) |
| Mar 2017 | - | -$106.51M(+7.7%) | -$421.07M(+0.8%) |
| Dec 2016 | -$424.59M(-43.4%) | -$115.43M(-8.2%) | -$424.59M(-5.7%) |
| Sep 2016 | - | -$106.68M(-15.4%) | -$401.67M(-7.6%) |
| Jun 2016 | - | -$92.45M(+16.0%) | -$373.32M(-5.5%) |
| Mar 2016 | - | -$110.03M(-18.9%) | -$353.81M(-19.5%) |
| Dec 2015 | -$296.01M(-60.7%) | -$92.51M(-18.1%) | -$296.01M(-18.8%) |
| Sep 2015 | - | -$78.33M(-7.4%) | -$249.21M(-15.3%) |
| Jun 2015 | - | -$72.94M(-39.7%) | -$216.08M(-12.5%) |
| Mar 2015 | - | -$52.22M(-14.2%) | -$192.03M(-4.2%) |
| Dec 2014 | -$184.21M | -$45.71M(-1.1%) | -$184.21M(-9.6%) |
| Sep 2014 | - | -$45.20M(+7.6%) | -$168.09M(-8.4%) |
| Jun 2014 | - | -$48.90M(-10.1%) | -$155.13M(-21.6%) |
| Date | Annual | Quarterly | TTM |
|---|---|---|---|
| Mar 2014 | - | -$44.41M(-50.1%) | -$127.55M(-37.2%) |
| Dec 2013 | -$92.94M(-46.2%) | -$29.59M(+8.2%) | -$92.94M(-7.2%) |
| Sep 2013 | - | -$32.23M(-51.2%) | -$86.70M(-19.4%) |
| Jun 2013 | - | -$21.31M(-117.4%) | -$72.62M(-14.6%) |
| Mar 2013 | - | -$9.80M(+58.0%) | -$63.37M(+1.7%) |
| Dec 2012 | -$63.57M(-16.0%) | -$23.35M(-28.7%) | -$64.46M(-17.9%) |
| Sep 2012 | - | -$18.15M(-50.4%) | -$54.69M(-11.7%) |
| Jun 2012 | - | -$12.07M(-10.8%) | -$48.98M(+2.1%) |
| Mar 2012 | - | -$10.89M(+19.8%) | -$50.03M(+8.7%) |
| Dec 2011 | -$54.82M(-25.3%) | -$13.59M(-9.2%) | -$54.82M(-2.2%) |
| Sep 2011 | - | -$12.44M(+5.2%) | -$53.64M(-7.4%) |
| Jun 2011 | - | -$13.12M(+16.3%) | -$49.93M(-3.1%) |
| Mar 2011 | - | -$15.68M(-26.3%) | -$48.44M(-9.9%) |
| Dec 2010 | -$43.74M(+9.1%) | -$12.41M(-42.2%) | -$44.07M(-10.9%) |
| Sep 2010 | - | -$8.73M(+24.9%) | -$39.73M(+2.3%) |
| Jun 2010 | - | -$11.63M(-2.8%) | -$40.65M(+21.0%) |
| Mar 2010 | - | -$11.31M(-40.1%) | -$51.44M(-6.9%) |
| Dec 2009 | -$48.11M(-72.8%) | -$8.07M(+16.4%) | -$48.11M(-0.5%) |
| Sep 2009 | - | -$9.65M(+56.9%) | -$47.85M(-15.5%) |
| Jun 2009 | - | -$22.41M(-180.9%) | -$41.44M(-30.1%) |
| Mar 2009 | - | -$7.98M(-2.1%) | -$31.86M(-14.5%) |
| Dec 2008 | -$27.84M(+70.1%) | -$7.81M(-141.6%) | -$27.84M(-21.5%) |
| Sep 2008 | - | -$3.23M(+74.8%) | -$22.91M(+65.9%) |
| Jun 2008 | - | -$12.83M(-224.3%) | -$67.22M(+3.1%) |
| Mar 2008 | - | -$3.96M(-36.8%) | -$69.34M(+22.4%) |
| Dec 2007 | -$93.18M(-135.9%) | -$2.89M(+93.9%) | -$89.38M(+7.4%) |
| Sep 2007 | - | -$47.54M(-217.9%) | -$96.48M(-67.7%) |
| Jun 2007 | - | -$14.95M(+37.7%) | -$57.54M(-7.2%) |
| Mar 2007 | - | -$23.99M(-140.2%) | -$53.70M(-35.9%) |
| Dec 2006 | -$39.50M(+9.1%) | -$9.99M(-16.1%) | -$39.50M(+11.1%) |
| Sep 2006 | - | -$8.60M(+22.5%) | -$44.43M(+4.4%) |
| Jun 2006 | - | -$11.11M(-13.4%) | -$46.49M(+0.2%) |
| Mar 2006 | - | -$9.80M(+34.3%) | -$46.59M(-7.2%) |
| Dec 2005 | -$43.47M(-34.7%) | -$14.92M(-39.8%) | -$43.47M(-27.5%) |
| Sep 2005 | - | -$10.67M(+4.8%) | -$34.09M(-14.2%) |
| Jun 2005 | - | -$11.20M(-67.7%) | -$29.84M(-16.5%) |
| Mar 2005 | - | -$6.68M(-20.8%) | -$25.61M(+20.6%) |
| Dec 2004 | -$32.26M(-57.8%) | -$5.53M(+13.9%) | -$32.26M(+31.8%) |
| Sep 2004 | - | -$6.43M(+7.9%) | -$47.31M(-15.8%) |
| Jun 2004 | - | -$6.97M(+47.7%) | -$40.84M(-14.6%) |
| Mar 2004 | - | -$13.33M(+35.2%) | -$35.65M(-51.2%) |
| Dec 2003 | -$20.45M(-384.3%) | -$20.58M(>-9900.0%) | -$23.59M(-684.6%) |
| Sep 2003 | - | $44.00K(+102.5%) | -$3.01M(+1.4%) |
| Jun 2003 | - | -$1.78M(-40.9%) | -$3.05M(-140.9%) |
| Mar 2003 | - | -$1.27M | -$1.27M |
| Dec 2002 | -$4.22M | - | - |
FAQ
- What is Alnylam Pharmaceuticals, Inc. annual operating income?
- What is the all-time high annual operating profit for Alnylam Pharmaceuticals, Inc.?
- What is Alnylam Pharmaceuticals, Inc. annual operating profit year-on-year change?
- What is Alnylam Pharmaceuticals, Inc. quarterly operating income?
- What is the all-time high quarterly operating profit for Alnylam Pharmaceuticals, Inc.?
- What is Alnylam Pharmaceuticals, Inc. quarterly operating profit year-on-year change?
- What is Alnylam Pharmaceuticals, Inc. TTM operating income?
- What is the all-time high TTM operating profit for Alnylam Pharmaceuticals, Inc.?
- What is Alnylam Pharmaceuticals, Inc. TTM operating profit year-on-year change?
What is Alnylam Pharmaceuticals, Inc. annual operating income?
The current annual operating profit of ALNY is -$176.88M
What is the all-time high annual operating profit for Alnylam Pharmaceuticals, Inc.?
Alnylam Pharmaceuticals, Inc. all-time high annual operating income is -$4.22M
What is Alnylam Pharmaceuticals, Inc. annual operating profit year-on-year change?
Over the past year, ALNY annual operating income has changed by +$105.29M (+37.31%)
What is Alnylam Pharmaceuticals, Inc. quarterly operating income?
The current quarterly operating profit of ALNY is $367.98M
What is the all-time high quarterly operating profit for Alnylam Pharmaceuticals, Inc.?
Alnylam Pharmaceuticals, Inc. all-time high quarterly operating income is $367.98M
What is Alnylam Pharmaceuticals, Inc. quarterly operating profit year-on-year change?
Over the past year, ALNY quarterly operating income has changed by +$444.89M (+578.49%)
What is Alnylam Pharmaceuticals, Inc. TTM operating income?
The current TTM operating profit of ALNY is $264.70M
What is the all-time high TTM operating profit for Alnylam Pharmaceuticals, Inc.?
Alnylam Pharmaceuticals, Inc. all-time high TTM operating income is $264.70M
What is Alnylam Pharmaceuticals, Inc. TTM operating profit year-on-year change?
Over the past year, ALNY TTM operating income has changed by +$452.83M (+240.70%)