Annual Operating Profit
-$176.89M$105.29M+37.31%
Summary
- Current Value
- As of today, ALNY annual operating profit is -$176.89M, up +37.31% on
- Historical Performance
- ALNY annual operating profit is up +75.04% over the past 3 years, and up +81.17% over the past 5 years
- All-Time High Comparison
- ALNY annual operating profit is currently -4089.60% below its historical high of -$4.22M set on
- 3-Year Low Comparison
- ALNY annual operating profit is +77.47% above its 3-year low of -$785.07M reached on an earlier date
- Sector Comparison
- ALNY annual operating profit is higher than 9.49% of companies in Healthcare sector
Operating Profit Chart
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Series
SUGGESTED SERIES
Performance
| Metric | Date | Value | 1Y | 3Y | 5Y | 15Y |
|---|---|---|---|---|---|---|
| Annual Operating Profit | -$176.89M | +37.3% | +75.0% | +81.2% | -267.7% | |
| Quarterly Operating Profit | $367.98M | +578.5% | +242.6% | +263.4% | +4316.1% | |
| TTM Operating Profit | $264.70M | +240.7% | +133.5% | +128.4% | +766.3% | |
| Price | $400.17 | +71.3% | +68.4% | +207.9% | +3958.5% | |
| PE Ratio | 1,663.91 | – | – | – | – | |
| Annual Revenue | $2.25B | +23.0% | +166.3% | +923.1% | +2136.3% | |
| Annual EPS | -$2.18 | +38.2% | +69.7% | +73.1% | -91.1% | |
| Annual Gross Profit | $1.92B | +26.8% | +173.4% | +888.7% | +1936.0% | |
| Annual Operating Expenses | $2.10B | +16.8% | +48.8% | +85.3% | +1314.0% |
Operating Profit Highs
| Period | High | Date | Current |
|---|---|---|---|
| 3Y | -$176.89M | at high | |
| 5Y | -$176.89M | at high | |
| All | -$4.22M | -4089.6% |
Operating Profit Lows
| Period | Low | Date | Current |
|---|---|---|---|
| 3Y | -$785.07M | N/A | +77.5% |
| 5Y | -$828.44M | N/A | +78.7% |
| All | -$939.43M | +81.2% |
Operating Profit History
FAQ
What is the current annual operating profit of ALNY?
As of today, ALNY annual operating profit is -$176.89M
What is 1-year change in ALNY annual operating profit?
ALNY annual operating profit is up +37.31% year-over-year
What is 3-year change in ALNY annual operating profit?
ALNY annual operating profit is up +75.04% over the past 3 years
How far is ALNY annual operating profit from its all-time high?
ALNY annual operating profit is currently -4089.60% below its historical high of -$4.22M set on December 31, 2002
How does ALNY annual operating profit rank versus sector peers?
ALNY annual operating profit is higher than 9.49% of companies in Healthcare sector
When is ALNY next annual earnings release?
The next annual earnings release for ALNY is on
Quarterly Operating Profit
$367.98M$384.18M+2,371.63%
Summary
- Current Value
- As of today, ALNY quarterly operating profit is $367.98M, up +2371.63% on
- Historical Performance
- ALNY quarterly operating profit is up +578.49% year-over-year, and up +242.61% over the past 3 years
- All-Time High Comparison
- ALNY quarterly operating profit is currently at its all-time high
- 3-Year Low Comparison
- ALNY quarterly operating profit is +260.11% above its 3-year low of -$229.83M reached on
- Sector Comparison
- ALNY quarterly operating profit is higher than 94.92% of companies in Healthcare sector
Performance
| Metric | Date | Value | 3M | 1Y | 3Y | 5Y |
|---|---|---|---|---|---|---|
| Quarterly Operating Profit | $367.98M | +2371.6% | +578.5% | +242.6% | +263.4% | |
| Annual Operating Profit | -$176.89M | – | +37.3% | +75.0% | +81.2% | |
| TTM Operating Profit | $264.70M | +246.9% | +240.7% | +133.5% | +128.4% | |
| Price | $400.17 | -13.2% | +71.3% | +68.4% | +207.9% | |
| PE Ratio | 1,663.91 | -13.2% | – | – | – | |
| Quarterly Revenue | $1.25B | +61.4% | +149.3% | +372.6% | +892.5% | |
| Quarterly EPS | $1.84 | +462.6% | +312.1% | +155.4% | +184.3% | |
| Quarterly Gross Profit | $1.05B | +66.3% | +152.7% | +369.9% | +908.0% | |
| Quarterly Operating Expenses | $680.89M | +5.3% | +38.4% | +41.5% | +106.8% |
Quarterly Operating Profit Highs
| Period | High | Date | Current |
|---|---|---|---|
| 1Y | $367.98M | at high | |
| 3Y | $367.98M | at high | |
| 5Y | $367.98M | at high | |
| All | $367.98M | at high |
Quarterly Operating Profit Lows
| Period | Low | Date | Current |
|---|---|---|---|
| 1Y | -$105.16M | N/A | +449.9% |
| 3Y | -$229.83M | +260.1% | |
| 5Y | -$258.04M | +242.6% | |
| All | -$298.07M | +223.4% |
Quarterly Operating Profit History
FAQ
What is the current quarterly operating profit of ALNY?
As of today, ALNY quarterly operating profit is $367.98M
What is ALNY quarterly operating profit most recent change?
ALNY quarterly operating profit was up +2371.63% on September 30, 2025
What is 1-year change in ALNY quarterly operating profit?
ALNY quarterly operating profit is up +578.49% year-over-year
How far is ALNY quarterly operating profit from its all-time high?
ALNY quarterly operating profit is currently at its all-time high
How does ALNY quarterly operating profit rank versus sector peers?
ALNY quarterly operating profit is higher than 94.92% of companies in Healthcare sector
When is ALNY next earnings release?
The next earnings release for ALNY is on
TTM Operating Profit
$264.70M$444.89M+246.90%
Summary
- Current Value
- As of today, ALNY TTM operating profit is $264.70M, up +246.90% on
- Historical Performance
- ALNY TTM operating profit is up +240.70% year-over-year, and up +133.46% over the past 3 years
- All-Time High Comparison
- ALNY TTM operating profit is currently at its all-time high
- 3-Year Low Comparison
- ALNY TTM operating profit is +132.03% above its 3-year low of -$826.29M reached on
- Sector Comparison
- ALNY TTM operating profit is higher than 89.38% of companies in Healthcare sector
Performance
| Metric | Date | Value | 3M | 1Y | 3Y | 5Y |
|---|---|---|---|---|---|---|
| TTM Operating Profit | $264.70M | +246.9% | +240.7% | +133.5% | +128.4% | |
| Annual Operating Profit | -$176.89M | – | +37.3% | +75.0% | +81.2% | |
| Quarterly Operating Profit | $367.98M | +2371.6% | +578.5% | +242.6% | +263.4% | |
| Price | $400.17 | -13.2% | +71.3% | +68.4% | +207.9% | |
| PE Ratio | 1,663.91 | -13.2% | – | – | – | |
| TTM Revenue | $3.21B | +30.4% | +53.2% | +234.1% | +700.6% | |
| TTM EPS | $0.24 | +109.8% | +109.2% | +102.5% | +103.1% | |
| TTM Gross Profit | $2.69B | +30.8% | +50.6% | +234.3% | +706.9% | |
| Quarterly Operating Expenses | $680.89M | +5.3% | +38.4% | +41.5% | +106.8% |
TTM Operating Profit Highs
| Period | High | Date | Current |
|---|---|---|---|
| 1Y | $264.70M | at high | |
| 3Y | $264.70M | at high | |
| 5Y | $264.70M | at high | |
| All | $264.70M | at high |
TTM Operating Profit Lows
| Period | Low | Date | Current |
|---|---|---|---|
| 1Y | -$180.19M | +246.9% | |
| 3Y | -$826.29M | +132.0% | |
| 5Y | -$828.44M | N/A | +131.9% |
| All | -$960.80M | +127.5% |
TTM Operating Profit History
FAQ
What is the current TTM operating profit of ALNY?
As of today, ALNY TTM operating profit is $264.70M
What is ALNY TTM operating profit most recent change?
ALNY TTM operating profit was up +246.90% on September 30, 2025
What is 1-year change in ALNY TTM operating profit?
ALNY TTM operating profit is up +240.70% year-over-year
How far is ALNY TTM operating profit from its all-time high?
ALNY TTM operating profit is currently at its all-time high
How does ALNY TTM operating profit rank versus sector peers?
ALNY TTM operating profit is higher than 89.38% of companies in Healthcare sector
When is ALNY next earnings release?
The next earnings release for ALNY is on
Operating Profit Formula
Operating Profit = Gross Profit −
Data Sources & References
- ALNY Official Website www.alnylam.com
- Most Recent Quarterly Report (10-Q) www.sec.gov/Archives/edgar/data/1178670/000119312525230201/0001193125-25-230201-index.htm
- Most Recent Annual Report (10-K) www.sec.gov/Archives/edgar/data/1178670/000117867025000026/0001178670-25-000026-index.htm
- ALNY Profile on Yahoo Finance finance.yahoo.com/quote/ALNY
- ALNY Profile on NASDAQ.com www.nasdaq.com/market-activity/stocks/alny