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Alnylam Pharmaceuticals, Inc. (ALNY) Gross Margin

Annual Gross Margin:

85.62%+2.60%(+3.13%)
December 31, 2024

Summary

  • As of today, ALNY annual gross profit margin is 85.62%, with the most recent change of +2.60% (+3.13%) on December 31, 2024.
  • During the last 3 years, ALNY annual gross margin has risen by +2.22% (+2.66%).
  • ALNY annual gross margin is now -9.93% below its all-time high of 95.06%, reached on December 31, 2010.

Performance

1-Year Change

+3.13%

3-Year Change

+2.66%

5-Year Change

-3.36%

15-Year Change

+0.58%

ALNY Gross Margin Chart

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Highlights

Sector Percentile

85.01%
ALNY annual gross profit margin is higher than 85.01% of companies in Healthcare sector

Range

All-Time High

95.06%
ALNY annual gross profit margin is currently -9.93% below its historical high of 95.06%

3-Year Low

83.02%
ALNY annual gross profit margin is currently +3.13% above its 3-year low

Earnings dates

Last Annual Earnings Report Date

Dec 31, 2024
ALNY previous annual earnings announcement was published on Dec 31, 2024

Next Annual Earnings Report Date

Feb 12, 2026
ALNY next annual earnings announcement is scheduled for Feb 12, 2026

OtherALNYprofitability metrics

Annual Revenue

$2.25B
ALNY annual revenue is $2.25 billion

Annual Gross Profit

$1.92B
ALNY annual gross profit is $1.92 billion

Annual Operating Margin

-7.87%
ALNY annual operating profit margin is -7.87%

Annual Net Margin

-12.37%
ALNY annual net profit margin is -12.37%

Quarterly Gross Margin:

83.98%+2.46%(+3.02%)
September 30, 2025

Summary

  • As of today, ALNY quarterly gross profit margin is 83.98%, with the most recent change of +2.46% (+3.02%) on September 30, 2025.
  • Over the past year, ALNY quarterly gross margin has increased by +1.13% (+1.36%).
  • ALNY quarterly gross margin is now -10.61% below its all-time high of 93.95%, reached on December 31, 2011.

Performance

3-Month Change

+3.02%

1-Year Change

+1.36%

3-Year Change

-0.54%

5-Year Change

+1.57%

ALNY Quarterly Gross Margin Chart

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Highlights

Sector Percentile

81.68%
ALNY quarterly gross profit margin is higher than 81.68% of companies in Healthcare sector

Range

All-Time High

93.95%
ALNY quarterly gross profit margin is currently -10.61% below its historical high of 93.95%

3-Year Low

73.22%
ALNY quarterly gross profit margin is currently +14.70% above its 3-year low

Earnings dates

Last Quarterly Earnings Report Date

Sep 30, 2025
ALNY previous earnings announcement was published on Sep 30, 2025

Next Quarterly Earnings Report Date

Feb 12, 2026
ALNY next earnings announcement is scheduled for Feb 12, 2026

OtherALNYprofitability metrics

Quarterly Revenue

$1.25B
ALNY quarterly revenue is $1.25 billion

Quarterly Gross Profit

$1.05B
ALNY quarterly gross profit is $1.05 billion

Quarterly Operating Margin

29.46%
ALNY quarterly operating profit margin is 29.46%

Quarterly Net Margin

20.10%
ALNY quarterly net profit margin is 20.10%

Gross Margin Formula

Gross Margin =  Gross Profit
Revenue ✕ 100%

Annual Gross Margin

85.62%
ALNY annual gross profit margin is 85.62%

Annual Gross Profit

$1.92B
ALNY annual gross profit is $1.92 billion

Annual Revenue

$2.25B
ALNY annual revenue is $2.25 billion

ALNY Gross Margin Trends

PeriodPeriodAnnualAnnualQuarterlyQuarterly
1Y1 Year+3.1%+1.4%
3Y3 Years+2.7%-0.5%
5Y5 Years-3.4%+1.6%

ALNY Gross Margin Highs & Lows

PeriodPeriodAnnual vs HighAnnual vs HighAnnual vs LowAnnual vs LowQuarter. vs HighQuarter. vs HighQuarter. vs LowQuarter. vs Low
3Y3-Yearat high+3.1%-6.3%+14.7%
5Y5-Year-3.4%+3.1%-6.3%+14.7%
All-TimeAll-Time-9.9%>+9999.0%-10.6%+232.2%

ALNY Gross Margin History

DateAnnualQuarterly
Sep 2025
-
83.98%(+3.0%)
Jun 2025
-
81.52%(-7.4%)
Mar 2025
-
88.04%(+6.5%)
Dec 2024
85.62%(+3.1%)
82.67%(-0.2%)
Sep 2024
-
82.85%(-7.5%)
Jun 2024
-
89.59%(+3.4%)
Mar 2024
-
86.65%(+7.7%)
Dec 2023
83.02%(-0.8%)
80.47%(-9.4%)
Sep 2023
-
88.77%(+21.2%)
Jun 2023
-
73.22%(-11.6%)
Mar 2023
-
82.82%(-2.2%)
Dec 2022
83.73%(+0.4%)
84.70%(+0.3%)
Sep 2022
-
84.44%(+3.2%)
Jun 2022
-
81.85%(-1.7%)
Mar 2022
-
83.29%(-2.5%)
Dec 2021
83.40%(-0.9%)
85.43%(+3.4%)
Sep 2021
-
82.59%(+0.2%)
Jun 2021
-
82.43%(-0.1%)
Mar 2021
-
82.51%(-4.0%)
Dec 2020
84.16%(-5.0%)
85.92%(+3.9%)
Sep 2020
-
82.68%(+2.3%)
Jun 2020
-
80.83%(-6.7%)
Mar 2020
-
86.63%(+4.4%)
Dec 2019
88.60%(-0.4%)
83.01%(-10.3%)
Sep 2019
-
92.56%(+35.1%)
Jun 2019
-
68.53%(+28.6%)
Mar 2019
-
53.27%(-42.1%)
Dec 2018
89.00%(+4.5%)
92.08%(+245.0%)
Sep 2018
-
-63.51%(>-9900.0%)
Jun 2018
-
0.00%(0.0%)
Mar 2018
-
0.00%(-100.0%)
Dec 2017
85.13%(>+9900.0%)
90.21%(>+9900.0%)
Sep 2017
-
0.00%(0.0%)
Jun 2017
-
0.00%(0.0%)
Mar 2017
-
0.00%(0.0%)
Dec 2016
0.00%(0.0%)
0.00%(0.0%)
Sep 2016
-
0.00%(0.0%)
Jun 2016
-
0.00%(0.0%)
Mar 2016
-
0.00%(0.0%)
Dec 2015
0.00%(0.0%)
0.00%(0.0%)
Sep 2015
-
0.00%(0.0%)
Jun 2015
-
0.00%(0.0%)
Mar 2015
-
0.00%(0.0%)
Dec 2014
0.00%
0.00%(0.0%)
DateAnnualQuarterly
Sep 2014
-
0.00%(0.0%)
Jun 2014
-
0.00%(0.0%)
Mar 2014
-
0.00%(0.0%)
Dec 2013
0.00%(0.0%)
0.00%(0.0%)
Sep 2013
-
0.00%(0.0%)
Jun 2013
-
0.00%(0.0%)
Mar 2013
-
0.00%(0.0%)
Dec 2012
0.00%(-100.0%)
0.00%(0.0%)
Sep 2012
-
0.00%(-100.0%)
Jun 2012
-
87.53%(-2.4%)
Mar 2012
-
89.70%(-4.5%)
Dec 2011
93.81%(-1.3%)
93.95%(+0.0%)
Sep 2011
-
93.93%(>+9900.0%)
Jun 2011
-
0.00%(0.0%)
Mar 2011
-
0.00%(-100.0%)
Dec 2010
95.06%(+1.1%)
93.91%(>+9900.0%)
Sep 2010
-
0.00%(0.0%)
Jun 2010
-
0.00%(0.0%)
Mar 2010
-
0.00%(0.0%)
Dec 2009
94.04%(>+9900.0%)
0.00%(0.0%)
Sep 2009
-
0.00%(0.0%)
Jun 2009
-
0.00%(0.0%)
Mar 2009
-
0.00%(0.0%)
Dec 2008
0.00%(0.0%)
0.00%(0.0%)
Sep 2008
-
0.00%(0.0%)
Jun 2008
-
0.00%(0.0%)
Mar 2008
-
0.00%(0.0%)
Dec 2007
0.00%(0.0%)
0.00%(0.0%)
Sep 2007
-
0.00%(0.0%)
Jun 2007
-
0.00%(0.0%)
Mar 2007
-
0.00%(0.0%)
Dec 2006
0.00%(0.0%)
0.00%(0.0%)
Sep 2006
-
0.00%(0.0%)
Jun 2006
-
0.00%(0.0%)
Mar 2006
-
0.00%(0.0%)
Dec 2005
0.00%(0.0%)
0.00%(0.0%)
Sep 2005
-
0.00%(0.0%)
Jun 2005
-
0.00%(0.0%)
Mar 2005
-
0.00%(0.0%)
Dec 2004
0.00%(0.0%)
0.00%(0.0%)
Sep 2004
-
0.00%(0.0%)
Jun 2004
-
0.00%(0.0%)
Mar 2004
-
0.00%
Dec 2003
0.00%
-

FAQ

  • What is Alnylam Pharmaceuticals, Inc. annual gross profit margin?
  • What is the all-time high annual gross margin for Alnylam Pharmaceuticals, Inc.?
  • What is Alnylam Pharmaceuticals, Inc. annual gross margin year-on-year change?
  • What is Alnylam Pharmaceuticals, Inc. quarterly gross profit margin?
  • What is the all-time high quarterly gross margin for Alnylam Pharmaceuticals, Inc.?
  • What is Alnylam Pharmaceuticals, Inc. quarterly gross margin year-on-year change?

What is Alnylam Pharmaceuticals, Inc. annual gross profit margin?

The current annual gross margin of ALNY is 85.62%

What is the all-time high annual gross margin for Alnylam Pharmaceuticals, Inc.?

Alnylam Pharmaceuticals, Inc. all-time high annual gross profit margin is 95.06%

What is Alnylam Pharmaceuticals, Inc. annual gross margin year-on-year change?

Over the past year, ALNY annual gross profit margin has changed by +2.60% (+3.13%)

What is Alnylam Pharmaceuticals, Inc. quarterly gross profit margin?

The current quarterly gross margin of ALNY is 83.98%

What is the all-time high quarterly gross margin for Alnylam Pharmaceuticals, Inc.?

Alnylam Pharmaceuticals, Inc. all-time high quarterly gross profit margin is 93.95%

What is Alnylam Pharmaceuticals, Inc. quarterly gross margin year-on-year change?

Over the past year, ALNY quarterly gross profit margin has changed by +1.13% (+1.36%)
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