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Protagonist Therapeutics, Inc. (PTGX)

Profile

Full Name

Protagonist Therapeutics, Inc.

Ticker

NASDAQ: PTGX

Exchange

NASDAQ

Sector

Healthcare

Industry

Biotechnology

Country

United States

IPO

August 11, 2016

Indexes

Not included

Website

https://www.protagonist-inc.com

Employees

124

Key Details

Price

$95.35(3.36%)

Market Cap

$5.96B(Mid cap)

Last Dividend

-

TTM Dividend Yield

-

Annual Revenue

$434.43M(624.06% YoY)

Annual EPS

$4.23(404.02% YoY)

PE Ratio

150.56

Next earnings date

Feb 20, 2026

Next ex-dividend date

N/A

Next split date

N/A

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    Analyst ratings

    Price

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    Current Price

    $95.35
    PTGX price is $95.35

    30-Day Relative Volume

    1.31
    PTGX 30-day relative volume is 1.31

    Price Performance

    Price Most Recent Change

    +3.36%
    PTGX price was up +3.36% on Dec 12, 2025

    Price YTD Change

    +147.02%
    PTGX price is up +147.02% since January 1st

    Price 1-Year Change

    +136.13%
    PTGX price is up +136.13% year-on-year

    Price 3-Year Change

    +1119.31%
    PTGX price is up +1119.31% over the past 3 years

    Price Range

    Price All-Time High

    $95.39
    PTGX price is currently -0.04% below its historical high of $95.39

    Price 3-Year Low

    $7.45
    PTGX price is currently +1179.87% above its 3-year low

    Capitalization

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    Market cap

    Market Cap

    $5.96B
    PTGX market cap is $5.96 billion

    Market Cap 3-Year Change

    +1449.36%
    PTGX market cap is up +1449.36% over the past 3 years

    Market Cap All-Time High

    $5.96B
    PTGX market cap is currently at an all-time high

    Market Cap Sector Percentile

    88.48%
    PTGX market cap is higher than 88.48% of companies in Healthcare sector

    Shares Outstanding

    Shares Outstanding 1-Year Change

    +4.9%
    PTGX shares outstanding is up +4.9% year-on-year

    Shares Outstanding 3-Year Change

    +27.07%
    PTGX shares outstanding is up +27.07% over the past 3 years

    Technical Indicators

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    Beta

    -0.02
    PTGX beta is -0.02

    200-day SMA

    $59.34
    PTGX price is currently +60.67% above its 200-day simple moving average

    50-day SMA

    $80.91
    PTGX price is currently +17.85% above its 50-day simple moving average

    14-Day RSI

    71.29
    PTGX 14-day relative strength index is 71.29

    Volume

    1.31
    PTGX 30-day relative volume is 1.31

    ATR

    $3.04
    PTGX average true range is $3.04

    10-day Historical Volatility

    40.76%
    PTGX 10-day historical volatility is 40.76%

    Dividend

    Income Statement

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    Revenue

    Revenue

    $434.43M
    PTGX annual revenue is $434.43 million

    Revenue Analysts Estimate

    $66.81M
    PTGX annual revenue is currently +550.30% higher than the consensus analysts' forecast

    Revenue 1-Year Change

    +624.06%
    PTGX annual revenue is up +624.06% year-on-year

    Revenue Sector Percentile

    80.32%
    PTGX annual revenue is higher than 80.32% of companies in Healthcare sector

    EPS

    EPS

    $4.23
    PTGX annual earnings per share is $4.23

    EPS Analysts Estimate

    -$1.87
    PTGX annual earnings per share is currently +326.00% higher than the consensus analysts' forecast

    EPS 1-Year Change

    +404.02%
    PTGX annual earnings per share is up +404.02% year-on-year

    EPS Sector Percentile

    94.62%
    PTGX annual earnings per share is higher than 94.62% of companies in Healthcare sector

    Profit

    Gross Profit

    $431.47M
    PTGX annual gross profit is $431.47 million

    Gross Margin

    99.32%
    PTGX annual gross profit margin is 99.32%

    Operating Profit

    $252.84M
    PTGX annual operating income is $252.84 million

    Operating Margin

    58.20%
    PTGX annual operating profit margin is 58.20%

    Net Income

    $275.19M
    PTGX annual net profit is $275.19 million

    Net Margin

    63.34%
    PTGX annual net profit margin is 63.34%

    Expenses

    Total Expenses

    $181.59M
    PTGX annual total expenses is $181.59 million

    Operating Expenses

    $181.59M
    PTGX annual total operating expenses is $181.59 million

    Cost Of Goods Sold

    $2.96M
    PTGX annual cost of goods sold is $2.96 million

    Selling, General & Administrative Expenses

    $43.46M
    PTGX annual SG&A is $43.46 million

    Depreciation & Amortization

    $2.90M
    PTGX annual D&A is $2.90 million

    Interest Expense

    $0.00
    PTGX annual interest expense is $0.00

    Income Tax

    $4.22M
    PTGX annual income tax is $4.22 million

    EBIT & EBITDA

    EBIT

    $252.84M
    PTGX annual earnings before interest & taxes is $252.84 million

    EBITDA

    $255.74M
    PTGX annual EBITDA is $255.74 million

    Balance Sheet

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    Assets

    Total Assets

    $746.83M
    PTGX annual total assets is $746.83 million

    Non Current Assets

    $153.08M
    PTGX annual long term assets is $153.08 million

    Current Assets

    $591.64M
    PTGX annual total current assets is $591.64 million

    Cash and Cash Equivalents

    $97.25M
    PTGX annual cash & cash equivalents is $97.25 million

    Accounts Receivable

    $165.00M
    PTGX annual accounts receivable is $165.00 million

    Inventory

    $0.00
    PTGX annual inventory is $0.00

    Liabilities

    Total Liabilities

    $71.53M
    PTGX annual total liabilities is $71.53 million

    Long Term Liabilities

    $22.03M
    PTGX annual total long term liabilities is $22.03 million

    Current Liabilities

    $47.40M
    PTGX annual current liabilities is $47.40 million

    Accounts Payable

    $1.61M
    PTGX annual accounts payable is $1.61 million

    Debt

    Total Debt

    $10.87M
    PTGX annual total debt is $10.87 million

    Total Debt 1-Year Change

    +852.32%
    PTGX annual total debt is up +852.32% year-on-year

    Long Term Debt

    $10.36M
    PTGX annual long term debt is $10.36 million

    Short Term Debt

    $510.00K
    PTGX annual short term debt is $510.00 thousand

    Equity & Capital

    Shareholders Equity

    $675.29M
    PTGX annual stockholders equity is $675.29 million

    Book Value

    $675.29M
    PTGX annual book value is $675.29 million

    Retained Earnings

    -$340.52M
    PTGX annual retained earnings is -$340.52 million

    Working Capital

    $544.24M
    PTGX annual working capital is $544.24 million

    Cash Flow Statement

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    Cashflow Activities

    Cash From Operations

    $184.15M
    PTGX annual cash from operations is $184.15 million

    Cash From Operations 1-Year Change

    +362.19%
    PTGX annual cash from operations is up +362.19% year-on-year

    Cash From Investing

    -$299.48M
    PTGX annual cash from investing is -$299.48 million

    Cash From Investing 1-Year Change

    -662.86%
    PTGX annual cash from investing is down -662.86% year-on-year

    Cash From Financing

    $25.85M
    PTGX annual cash from financing is $25.85 million

    Cash From Financing 1-Year Change

    -84.83%
    PTGX annual cash from financing is down -84.83% year-on-year

    CAPEX

    CAPEX

    $1.35M
    PTGX annual capital expenditures is $1.35 million

    CAPEX 1-Year Change

    +122.5%
    PTGX annual capital expenditures is up +122.5% year-on-year

    Free Cash Flow

    Free Cash Flow

    $182.80M
    PTGX annual free cash flow is $182.80 million

    Free Cash Flow 1-Year Change

    +358.02%
    PTGX annual free cash flow is up +358.02% year-on-year

    Profitability Ratios

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    Margins

    Gross Margin

    99.32%
    PTGX annual gross profit margin is 99.32%

    Operating Margin

    58.20%
    PTGX annual operating profit margin is 58.20%

    Net Margin

    63.34%
    PTGX annual net profit margin is 63.34%

    ROA & ROE

    ROA

    49.81%
    PTGX annual return on assets is 49.81%

    ROE

    54.39%
    PTGX annual return on equity is 54.39%

    Valuation

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    PE Ratio

    PE Ratio

    150.56
    PTGX price to earnings ratio is 150.56

    PE Ratio Sector Percentile

    92.21%
    PTGX price to earnings ratio is higher than 92.21% of companies in Healthcare sector

    PB Ratio

    PB Ratio

    9.24
    PTGX price to book ratio is 9.24

    PB Ratio Sector Percentile

    86.83%
    PTGX price to book ratio is higher than 86.83% of companies in Healthcare sector

    PS Ratio

    PS Ratio

    28.49
    PTGX price to sales ratio is 28.49

    PS Ratio Sector Percentile

    82.32%
    PTGX price to sales ratio is higher than 82.32% of companies in Healthcare sector

    Enterprise value

    Enterprise Value

    $5.40B
    PTGX enterprise value is $5.40 billion

    Enterprise Value Sector Percentile

    87.57%
    PTGX enterprise value is higher than 87.57% of companies in Healthcare sector

    EV/EBITDA

    EV/EBITDA

    262.99
    PTGX EV/EBITDA is 262.99

    EV/EBITDA Sector Percentile

    99.73%
    PTGX EV/EBITDA is higher than 99.73% of companies in Healthcare sector

    Financial Health

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    Liquidity

    Current Ratio

    12.48
    PTGX annual current ratio is 12.48

    Quick Ratio

    12.48
    PTGX annual quick ratio is 12.48

    Leverage

    Debt To Equity

    0.02
    PTGX annual debt to equity ratio is 0.02

    Interest Coverage Ratio

    -
    PTGX annual interest coverage ratio value is unknown

    Risk & Stability

    F-Score

    7
    PTGX piotroski f-score is 7

    Altman Z-Score

    51.93
    PTGX altman z-score is 51.93

    Analyst ratings

    Recent major analysts updates

    Dec 8, 25 Citigroup
    Buy
    Nov 10, 25 Citigroup
    Buy
    Nov 7, 25 JP Morgan
    Overweight
    Nov 7, 25 Citizens
    Market Outperform
    Nov 7, 25 Barclays
    Overweight
    Oct 28, 25 Wedbush
    Outperform
    Oct 28, 25 Truist Securities
    Buy
    Oct 28, 25 BTIG
    Buy
    Oct 17, 25 Citigroup
    Buy
    Oct 8, 25 HC Wainwright & Co.
    Buy

    Institutional Ownership

    Screeners with PTGX included

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    Healthcare sector
    • What is the ticker symbol for Protagonist Therapeutics, Inc.?
    • Does Protagonist Therapeutics, Inc. pay dividends?
    • What sector is Protagonist Therapeutics, Inc. in?
    • What industry is Protagonist Therapeutics, Inc. in?
    • What country is Protagonist Therapeutics, Inc. based in?
    • When did Protagonist Therapeutics, Inc. go public?
    • Is Protagonist Therapeutics, Inc. in the S&P 500?
    • Is Protagonist Therapeutics, Inc. in the NASDAQ 100?
    • Is Protagonist Therapeutics, Inc. in the Dow Jones?
    • When was Protagonist Therapeutics, Inc.'s last earnings report?
    • When does Protagonist Therapeutics, Inc. report earnings?

    What is the ticker symbol for Protagonist Therapeutics, Inc.?

    The ticker symbol for Protagonist Therapeutics, Inc. is NASDAQ:PTGX

    Does Protagonist Therapeutics, Inc. pay dividends?

    No, Protagonist Therapeutics, Inc. does not pay dividends

    What sector is Protagonist Therapeutics, Inc. in?

    Protagonist Therapeutics, Inc. is in the Healthcare sector

    What industry is Protagonist Therapeutics, Inc. in?

    Protagonist Therapeutics, Inc. is in the Biotechnology industry

    What country is Protagonist Therapeutics, Inc. based in?

    Protagonist Therapeutics, Inc. is headquartered in United States

    When did Protagonist Therapeutics, Inc. go public?

    Protagonist Therapeutics, Inc.'s initial public offering (IPO) was on August 11, 2016

    Is Protagonist Therapeutics, Inc. in the S&P 500?

    No, Protagonist Therapeutics, Inc. is not included in the S&P 500 index

    Is Protagonist Therapeutics, Inc. in the NASDAQ 100?

    No, Protagonist Therapeutics, Inc. is not included in the NASDAQ 100 index

    Is Protagonist Therapeutics, Inc. in the Dow Jones?

    No, Protagonist Therapeutics, Inc. is not included in the Dow Jones index

    When was Protagonist Therapeutics, Inc.'s last earnings report?

    Protagonist Therapeutics, Inc.'s most recent earnings report was on November 6, 2025

    When does Protagonist Therapeutics, Inc. report earnings?

    The next expected earnings date for Protagonist Therapeutics, Inc. is February 20, 2026
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