Annual Operating Profit
-$300.10M$197.78M+39.72%
Summary
- Current Value
- As of today, MDGL annual operating profit is -$300.10M, up +39.72% on
- Historical Performance
- MDGL annual operating profit is down -2.22% over the past 3 years, down -45.45% over the past 5 years
- All-Time High Comparison
- MDGL annual operating profit is currently -472.61% below its historical high of $80.54M set on
- 3-Year Low Comparison
- MDGL annual operating profit is +39.72% above its 3-year low of -$497.88M reached on
- Sector Comparison
- MDGL annual operating profit is higher than 4.56% of companies in Healthcare sector
Operating Profit Chart
SUGGESTED SERIES
Performance
| Metric | Date | Value | 1Y | 3Y | 5Y | 15Y |
|---|---|---|---|---|---|---|
| Annual Operating Profit | -$300.10M | +39.7% | -2.2% | -45.5% | -713.3% | |
| Quarterly Operating Profit | -$56.31M | -19.3% | +34.9% | +8.8% | -368.9% | |
| TTM Operating Profit | -$322.62M | -4.1% | +2.4% | -38.4% | -676.1% | |
| Price | $524.38 | +50.0% | +205.9% | +519.4% | +256.7% | |
| PE Ratio | - | – | – | – | – | |
| Annual Revenue | $958.40M | +432.1% | +100.0% | +100.0% | +6374.4% | |
| Annual EPS | -$12.85 | +41.3% | +25.4% | +1.9% | +60.5% | |
| Annual Gross Profit | $900.75M | +421.3% | +10000.0% | +10000.0% | +100.0% | |
| $1.20B | +79.0% | +309.7% | +483.4% | +3154.5% |
Operating Profit Highs
| Period | High | Date | Current |
|---|---|---|---|
| 3Y | -$293.57M | N/A | -2.2% |
| 5Y | -$206.32M | N/A | -45.5% |
| All | $80.54M | -472.6% |
Operating Profit Lows
| Period | Low | Date | Current |
|---|---|---|---|
| 3Y | -$497.88M | +39.7% | |
| 5Y | -$497.88M | +39.7% | |
| All | -$497.88M | +39.7% |
Operating Profit History
FAQ
- What is the current annual operating profit of MDGL?
- As of today, MDGL annual operating profit is -$300.10M
- What is 1-year change in MDGL annual operating profit?
- MDGL annual operating profit is up +39.72% year-over-year
- What is 3-year change in MDGL annual operating profit?
- MDGL annual operating profit is down -2.22% over the past 3 years
- How far is MDGL annual operating profit from its all-time high?
- MDGL annual operating profit is currently -472.61% below its historical high of $80.54M set on December 31, 2009
- How does MDGL annual operating profit rank versus sector peers?
- MDGL annual operating profit is higher than 4.56% of companies in Healthcare sector
- When is MDGL next annual earnings release?
- As of today, the next annual earnings release for MDGL has not been scheduled
Operating Profit Formula
Operating Profit = Gross Profit −
Quarterly Operating Profit
-$56.31M$36.42M+39.27%
Summary
- Current Value
- As of today, MDGL quarterly operating profit is -$56.31M, up +39.27% on
- Historical Performance
- MDGL quarterly operating profit is down -19.29% year-over-year, up +34.87% over the past 3 years
- All-Time High Comparison
- MDGL quarterly operating profit is currently -147.65% below its historical high of $118.17M set on
- 3-Year Low Comparison
- MDGL quarterly operating profit is +65.36% above its 3-year low of -$162.54M reached on
- Sector Comparison
- MDGL quarterly operating profit is higher than 8.41% of companies in Healthcare sector
Performance
| Metric | Date | Value | 3M | 1Y | 3Y | 5Y |
|---|---|---|---|---|---|---|
| Quarterly Operating Profit | -$56.31M | +39.3% | -19.3% | +34.9% | +8.8% | |
| Annual Operating Profit | -$300.10M | – | +39.7% | -2.2% | -45.5% | |
| TTM Operating Profit | -$322.62M | -2.9% | -4.1% | +2.4% | -38.4% | |
| Price | $524.38 | +5.5% | +50.0% | +205.9% | +519.4% | |
| PE Ratio | - | – | – | – | – | |
| Quarterly Revenue | $364.25M | +17.0% | +71.2% | +100.0% | +100.0% | |
| Quarterly EPS | -$1.99 | +38.9% | -4.4% | +57.6% | +46.6% | |
| Quarterly Gross Profit | $323.86M | +14.0% | +59.3% | +10000.0% | +10000.0% | |
| $380.17M | +0.9% | +51.7% | +340.4% | +516.6% |
Quarterly Operating Profit Highs
| Period | High | Date | Current |
|---|---|---|---|
| 1Y | -$47.20M | N/A | -19.3% |
| 3Y | -$47.20M | -19.3% | |
| 5Y | -$47.20M | -19.3% | |
| All | $118.17M | -147.7% |
Quarterly Operating Profit Lows
| Period | Low | Date | Current |
|---|---|---|---|
| 1Y | -$113.98M | +50.6% | |
| 3Y | -$162.54M | +65.4% | |
| 5Y | -$162.54M | +65.4% | |
| All | -$162.54M | +65.4% |
Quarterly Operating Profit History
FAQ
- What is the current quarterly operating profit of MDGL?
- As of today, MDGL quarterly operating profit is -$56.31M
- What is MDGL quarterly operating profit most recent change?
- MDGL quarterly operating profit was up +39.27% on June 30, 2026
- What is 1-year change in MDGL quarterly operating profit?
- MDGL quarterly operating profit is down -19.29% year-over-year
- How far is MDGL quarterly operating profit from its all-time high?
- MDGL quarterly operating profit is currently -147.65% below its historical high of $118.17M set on September 30, 2009
- How does MDGL quarterly operating profit rank versus sector peers?
- MDGL quarterly operating profit is higher than 8.41% of companies in Healthcare sector
- When is MDGL next earnings release?
- The next earnings release for MDGL is on
Operating Profit Formula
Operating Profit = Gross Profit −
TTM Operating Profit
-$322.62M$9.11M-2.90%
Summary
- Current Value
- As of today, MDGL TTM operating profit is -$322.62M, down -2.90% on
- Historical Performance
- MDGL TTM operating profit is down -4.13% year-over-year, up +2.38% over the past 3 years
- All-Time High Comparison
- MDGL TTM operating profit is currently -445.11% below its historical high of $93.48M set on
- 3-Year Low Comparison
- MDGL TTM operating profit is +41.13% above its 3-year low of -$548.05M reached on
- Sector Comparison
- MDGL TTM operating profit is higher than 3.83% of companies in Healthcare sector
Performance
| Metric | Date | Value | 3M | 1Y | 3Y | 5Y |
|---|---|---|---|---|---|---|
| TTM Operating Profit | -$322.62M | -2.9% | -4.1% | +2.4% | -38.4% | |
| Annual Operating Profit | -$300.10M | – | +39.7% | -2.2% | -45.5% | |
| Quarterly Operating Profit | -$56.31M | +39.3% | -19.3% | +34.9% | +8.8% | |
| Price | $524.38 | +5.5% | +50.0% | +205.9% | +519.4% | |
| PE Ratio | - | – | – | – | – | |
| TTM Revenue | $1.28B | +13.4% | +149.0% | +100.0% | +100.0% | |
| TTM EPS | -$12.88 | -0.7% | -0.3% | +30.9% | +11.8% | |
| TTM Gross Profit | $1.17B | +11.4% | +137.0% | +10000.0% | +10000.0% | |
| $380.17M | +0.9% | +51.7% | +340.4% | +516.6% |
TTM Operating Profit Highs
| Period | High | Date | Current |
|---|---|---|---|
| 1Y | -$300.10M | -7.5% | |
| 3Y | -$300.10M | -7.5% | |
| 5Y | -$233.06M | N/A | -38.4% |
| All | $93.48M | -445.1% |
TTM Operating Profit Lows
| Period | Low | Date | Current |
|---|---|---|---|
| 1Y | -$322.62M | at low | |
| 3Y | -$548.05M | +41.1% | |
| 5Y | -$548.05M | +41.1% | |
| All | -$548.05M | +41.1% |
TTM Operating Profit History
FAQ
- What is the current TTM operating profit of MDGL?
- As of today, MDGL TTM operating profit is -$322.62M
- What is MDGL TTM operating profit most recent change?
- MDGL TTM operating profit was down -2.90% on June 30, 2026
- What is 1-year change in MDGL TTM operating profit?
- MDGL TTM operating profit is down -4.13% year-over-year
- How far is MDGL TTM operating profit from its all-time high?
- MDGL TTM operating profit is currently -445.11% below its historical high of $93.48M set on March 31, 2010
- How does MDGL TTM operating profit rank versus sector peers?
- MDGL TTM operating profit is higher than 3.83% of companies in Healthcare sector
- When is MDGL next earnings release?
- The next earnings release for MDGL is on
Operating Profit Formula
Operating Profit = Gross Profit −
Data Sources & References
- MDGL Official Website www.madrigalpharma.com
- Most Recent Annual Report (10-K) www.sec.gov/Archives/edgar/data/1157601/000162828026009514/0001628280-26-009514-index.htm
- MDGL Profile on Yahoo Finance finance.yahoo.com/quote/MDGL
- MDGL Profile on NASDAQ.com www.nasdaq.com/market-activity/stocks/mdgl