Annual Operating Profit
-$300.10M$197.78M+39.72%
Summary
- Current Value
- As of today, MDGL annual operating profit is -$300.10M, up +39.72% on
- Historical Performance
- MDGL annual operating profit is down -2.22% over the past 3 years, down -45.45% over the past 5 years
- All-Time High Comparison
- MDGL annual operating profit is currently -472.61% below its historical high of $80.54M set on
- 3-Year Low Comparison
- MDGL annual operating profit is +39.72% above its 3-year low of -$497.88M reached on
- Sector Comparison
- MDGL annual operating profit is higher than 4.51% of companies in Healthcare sector
Operating Profit Chart
SUGGESTED SERIES
Performance
| Metric | Date | Value | 1Y | 3Y | 5Y | 15Y |
|---|---|---|---|---|---|---|
| Annual Operating Profit | -$300.10M | +39.7% | -2.2% | -45.5% | -713.3% | |
| Quarterly Operating Profit | -$92.72M | -16.9% | -18.4% | -75.0% | -745.5% | |
| TTM Operating Profit | -$313.51M | +26.3% | +0.3% | -41.5% | -712.1% | |
| Price | $499.86 | +76.8% | +104.8% | +375.1% | +219.5% | |
| PE Ratio | - | – | – | – | – | |
| Annual Revenue | $958.40M | +432.1% | +100.0% | +100.0% | +6374.4% | |
| Annual EPS | -$12.85 | +41.3% | +25.4% | +1.9% | +60.5% | |
| Annual Gross Profit | $900.75M | +421.3% | +10000.0% | +10000.0% | +100.0% | |
| $1.20B | +79.0% | +309.7% | +483.4% | +3154.5% |
Operating Profit Highs
| Period | High | Date | Current |
|---|---|---|---|
| 3Y | -$293.57M | N/A | -2.2% |
| 5Y | -$206.32M | N/A | -45.5% |
| All | $80.54M | -472.6% |
Operating Profit Lows
| Period | Low | Date | Current |
|---|---|---|---|
| 3Y | -$497.88M | +39.7% | |
| 5Y | -$497.88M | +39.7% | |
| All | -$497.88M | +39.7% |
Operating Profit History
FAQ
What is the current annual operating profit of MDGL?
As of today, MDGL annual operating profit is -$300.10M
What is 1-year change in MDGL annual operating profit?
MDGL annual operating profit is up +39.72% year-over-year
What is 3-year change in MDGL annual operating profit?
MDGL annual operating profit is down -2.22% over the past 3 years
How far is MDGL annual operating profit from its all-time high?
MDGL annual operating profit is currently -472.61% below its historical high of $80.54M set on December 31, 2009
How does MDGL annual operating profit rank versus sector peers?
MDGL annual operating profit is higher than 4.51% of companies in Healthcare sector
When is MDGL next annual earnings release?
As of today, the next annual earnings release for MDGL has not been scheduled
Operating Profit Formula
Operating Profit = Gross Profit −
Quarterly Operating Profit
-$92.72M$33.11M-55.55%
Summary
- Current Value
- As of today, MDGL quarterly operating profit is -$92.72M, down -55.55% on
- Historical Performance
- MDGL quarterly operating profit is down -16.91% year-over-year, down -18.37% over the past 3 years
- All-Time High Comparison
- MDGL quarterly operating profit is currently -178.46% below its historical high of $118.17M set on
- 3-Year Low Comparison
- MDGL quarterly operating profit is +42.95% above its 3-year low of -$162.54M reached on
- Sector Comparison
- MDGL quarterly operating profit is higher than 4.02% of companies in Healthcare sector
Performance
| Metric | Date | Value | 3M | 1Y | 3Y | 5Y |
|---|---|---|---|---|---|---|
| Quarterly Operating Profit | -$92.72M | -55.5% | -16.9% | -18.4% | -75.0% | |
| Annual Operating Profit | -$300.10M | – | +39.7% | -2.2% | -45.5% | |
| TTM Operating Profit | -$313.51M | -4.5% | +26.3% | +0.3% | -41.5% | |
| Price | $499.86 | +13.1% | +76.8% | +104.8% | +375.1% | |
| PE Ratio | - | – | – | – | – | |
| Quarterly Revenue | $311.34M | -3.0% | +126.8% | +100.0% | +100.0% | |
| Quarterly EPS | -$3.25 | -26.7% | +1.9% | +23.1% | +2.0% | |
| Quarterly Gross Profit | $284.10M | -4.1% | +114.7% | +10000.0% | +10000.0% | |
| $376.83M | +5.9% | +78.0% | +381.8% | +612.8% |
Quarterly Operating Profit Highs
| Period | High | Date | Current |
|---|---|---|---|
| 1Y | -$47.20M | -96.4% | |
| 3Y | -$47.20M | -96.4% | |
| 5Y | -$47.20M | -96.4% | |
| All | $118.17M | -178.5% |
Quarterly Operating Profit Lows
| Period | Low | Date | Current |
|---|---|---|---|
| 1Y | -$113.98M | +18.6% | |
| 3Y | -$162.54M | +43.0% | |
| 5Y | -$162.54M | +43.0% | |
| All | -$162.54M | +43.0% |
Quarterly Operating Profit History
FAQ
What is the current quarterly operating profit of MDGL?
As of today, MDGL quarterly operating profit is -$92.72M
What is MDGL quarterly operating profit most recent change?
MDGL quarterly operating profit was down -55.55% on March 31, 2026
What is 1-year change in MDGL quarterly operating profit?
MDGL quarterly operating profit is down -16.91% year-over-year
How far is MDGL quarterly operating profit from its all-time high?
MDGL quarterly operating profit is currently -178.46% below its historical high of $118.17M set on September 30, 2009
How does MDGL quarterly operating profit rank versus sector peers?
MDGL quarterly operating profit is higher than 4.02% of companies in Healthcare sector
When is MDGL next earnings release?
The next earnings release for MDGL is on
Operating Profit Formula
Operating Profit = Gross Profit −
TTM Operating Profit
-$313.51M$13.41M-4.47%
Summary
- Current Value
- As of today, MDGL TTM operating profit is -$313.51M, down -4.47% on
- Historical Performance
- MDGL TTM operating profit is up +26.26% year-over-year, up +0.26% over the past 3 years
- All-Time High Comparison
- MDGL TTM operating profit is currently -435.37% below its historical high of $93.48M set on
- 3-Year Low Comparison
- MDGL TTM operating profit is +42.80% above its 3-year low of -$548.05M reached on
- Sector Comparison
- MDGL TTM operating profit is higher than 4.39% of companies in Healthcare sector
Performance
| Metric | Date | Value | 3M | 1Y | 3Y | 5Y |
|---|---|---|---|---|---|---|
| TTM Operating Profit | -$313.51M | -4.5% | +26.3% | +0.3% | -41.5% | |
| Annual Operating Profit | -$300.10M | – | +39.7% | -2.2% | -45.5% | |
| Quarterly Operating Profit | -$92.72M | -55.5% | -16.9% | -18.4% | -75.0% | |
| Price | $499.86 | +13.1% | +76.8% | +104.8% | +375.1% | |
| PE Ratio | - | – | – | – | – | |
| TTM Revenue | $1.13B | +18.2% | +256.8% | +100.0% | +100.0% | |
| TTM EPS | -$12.80 | +0.5% | +29.1% | +29.3% | +9.0% | |
| TTM Gross Profit | $1.05B | +16.9% | +244.7% | +10000.0% | +10000.0% | |
| $376.83M | +5.9% | +78.0% | +381.8% | +612.8% |
TTM Operating Profit Highs
| Period | High | Date | Current |
|---|---|---|---|
| 1Y | -$300.10M | -4.5% | |
| 3Y | -$300.10M | -4.5% | |
| 5Y | -$221.65M | N/A | -41.5% |
| All | $93.48M | -435.4% |
TTM Operating Profit Lows
| Period | Low | Date | Current |
|---|---|---|---|
| 1Y | -$425.15M | N/A | +26.3% |
| 3Y | -$548.05M | +42.8% | |
| 5Y | -$548.05M | +42.8% | |
| All | -$548.05M | +42.8% |
TTM Operating Profit History
FAQ
What is the current TTM operating profit of MDGL?
As of today, MDGL TTM operating profit is -$313.51M
What is MDGL TTM operating profit most recent change?
MDGL TTM operating profit was down -4.47% on March 31, 2026
What is 1-year change in MDGL TTM operating profit?
MDGL TTM operating profit is up +26.26% year-over-year
How far is MDGL TTM operating profit from its all-time high?
MDGL TTM operating profit is currently -435.37% below its historical high of $93.48M set on March 31, 2010
How does MDGL TTM operating profit rank versus sector peers?
MDGL TTM operating profit is higher than 4.39% of companies in Healthcare sector
When is MDGL next earnings release?
The next earnings release for MDGL is on
Operating Profit Formula
Operating Profit = Gross Profit −
Data Sources & References
- MDGL Official Website www.madrigalpharma.com
- Most Recent Annual Report (10-K) www.sec.gov/Archives/edgar/data/1157601/000162828026009514/0001628280-26-009514-index.htm
- MDGL Profile on Yahoo Finance finance.yahoo.com/quote/MDGL
- MDGL Profile on NASDAQ.com www.nasdaq.com/market-activity/stocks/mdgl