Annual Operating Profit
-$497.88M$117.38M-30.85%
Summary
- Current Value
- As of today, MDGL annual operating profit is -$497.88M, down -30.85% on
- Historical Performance
- MDGL annual operating profit is down -105.32% over the past 3 years, and down -424.23% over the past 5 years
- All-Time High Comparison
- MDGL annual operating profit is currently -718.17% below its historical high of $80.54M set on
- 3-Year Low Comparison
- MDGL annual operating profit is at its 3-year low
- Sector Comparison
- MDGL annual operating profit is higher than 1.87% of companies in Healthcare sector
Operating Profit Chart
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Series
SUGGESTED SERIES
Performance
| Metric | Date | Value | 1Y | 3Y | 5Y | 15Y |
|---|---|---|---|---|---|---|
| Annual Operating Profit | -$497.88M | -30.9% | -105.3% | -424.2% | -718.2% | |
| Quarterly Operating Profit | -$113.98M | +2.0% | -41.7% | -93.9% | -1014.0% | |
| TTM Operating Profit | -$307.49M | +43.9% | -12.7% | -73.7% | -765.8% | |
| Price | $510.53 | +50.6% | +69.7% | +356.2% | +116.1% | |
| PE Ratio | - | – | – | – | – | |
| Annual Revenue | $180.13M | +100.0% | +100.0% | +100.0% | +24.9% | |
| Annual EPS | -$21.90 | -9.5% | -49.7% | -301.6% | -127.0% | |
| Annual Gross Profit | $172.80M | +10000.0% | +10000.0% | +10000.0% | +100.0% | |
| Annual Operating Expenses | $671.78M | +76.5% | +177.0% | +607.3% | +954.5% |
Operating Profit Highs
| Period | High | Date | Current |
|---|---|---|---|
| 3Y | -$293.57M | N/A | -69.6% |
| 5Y | -$206.67M | N/A | -140.9% |
| All | $80.54M | -718.2% |
Operating Profit Lows
| Period | Low | Date | Current |
|---|---|---|---|
| 3Y | -$497.88M | at low | |
| 5Y | -$497.88M | at low | |
| All | -$497.88M | at low |
Operating Profit History
FAQ
What is the current annual operating profit of MDGL?
As of today, MDGL annual operating profit is -$497.88M
What is 1-year change in MDGL annual operating profit?
MDGL annual operating profit is down -30.85% year-over-year
What is 3-year change in MDGL annual operating profit?
MDGL annual operating profit is down -105.32% over the past 3 years
How far is MDGL annual operating profit from its all-time high?
MDGL annual operating profit is currently -718.17% below its historical high of $80.54M set on December 31, 2009
How does MDGL annual operating profit rank versus sector peers?
MDGL annual operating profit is higher than 1.87% of companies in Healthcare sector
When is MDGL next annual earnings release?
The next annual earnings release for MDGL is on
Quarterly Operating Profit
-$113.98M$66.77M-141.46%
Summary
- Current Value
- As of today, MDGL quarterly operating profit is -$113.98M, down -141.46% on
- Historical Performance
- MDGL quarterly operating profit is up +2.00% year-over-year, and down -41.74% over the past 3 years
- All-Time High Comparison
- MDGL quarterly operating profit is currently -196.45% below its historical high of $118.17M set on
- 3-Year Low Comparison
- MDGL quarterly operating profit is +29.88% above its 3-year low of -$162.54M reached on
- Sector Comparison
- MDGL quarterly operating profit is higher than 2.86% of companies in Healthcare sector
Performance
| Metric | Date | Value | 3M | 1Y | 3Y | 5Y |
|---|---|---|---|---|---|---|
| Quarterly Operating Profit | -$113.98M | -141.5% | +2.0% | -41.7% | -93.9% | |
| Annual Operating Profit | -$497.88M | – | -30.9% | -105.3% | -424.2% | |
| TTM Operating Profit | -$307.49M | +0.8% | +43.9% | -12.7% | -73.7% | |
| Price | $510.53 | +18.8% | +50.6% | +69.7% | +356.2% | |
| PE Ratio | - | – | – | – | – | |
| Quarterly Revenue | $287.27M | +35.0% | +362.0% | +100.0% | +100.0% | |
| Quarterly EPS | -$5.08 | -166.8% | -3.3% | -7.0% | -35.4% | |
| Quarterly Gross Profit | $268.79M | +32.2% | +350.0% | +10000.0% | +10000.0% | |
| Quarterly Operating Expenses | $382.76M | +52.8% | +117.4% | +376.7% | +552.4% |
Quarterly Operating Profit Highs
| Period | High | Date | Current |
|---|---|---|---|
| 1Y | -$47.20M | -141.5% | |
| 3Y | -$47.20M | -141.5% | |
| 5Y | -$47.20M | -141.5% | |
| All | $118.17M | -196.4% |
Quarterly Operating Profit Lows
| Period | Low | Date | Current |
|---|---|---|---|
| 1Y | -$113.98M | at low | |
| 3Y | -$162.54M | +29.9% | |
| 5Y | -$162.54M | +29.9% | |
| All | -$162.54M | +29.9% |
Quarterly Operating Profit History
FAQ
What is the current quarterly operating profit of MDGL?
As of today, MDGL quarterly operating profit is -$113.98M
What is MDGL quarterly operating profit most recent change?
MDGL quarterly operating profit was down -141.46% on September 30, 2025
What is 1-year change in MDGL quarterly operating profit?
MDGL quarterly operating profit is up +2.00% year-over-year
How far is MDGL quarterly operating profit from its all-time high?
MDGL quarterly operating profit is currently -196.45% below its historical high of $118.17M set on September 30, 2009
How does MDGL quarterly operating profit rank versus sector peers?
MDGL quarterly operating profit is higher than 2.86% of companies in Healthcare sector
When is MDGL next earnings release?
The next earnings release for MDGL is on
TTM Operating Profit
-$307.49M$2.33M+0.75%
Summary
- Current Value
- As of today, MDGL TTM operating profit is -$307.49M, up +0.75% on
- Historical Performance
- MDGL TTM operating profit is up +43.90% year-over-year, and down -12.68% over the past 3 years
- All-Time High Comparison
- MDGL TTM operating profit is currently -428.93% below its historical high of $93.48M set on
- 3-Year Low Comparison
- MDGL TTM operating profit is +43.90% above its 3-year low of -$548.05M reached on
- Sector Comparison
- MDGL TTM operating profit is higher than 4.29% of companies in Healthcare sector
Performance
| Metric | Date | Value | 3M | 1Y | 3Y | 5Y |
|---|---|---|---|---|---|---|
| TTM Operating Profit | -$307.49M | +0.8% | +43.9% | -12.7% | -73.7% | |
| Annual Operating Profit | -$497.88M | – | -30.9% | -105.3% | -424.2% | |
| Quarterly Operating Profit | -$113.98M | -141.5% | +2.0% | -41.7% | -93.9% | |
| Price | $510.53 | +18.8% | +50.6% | +69.7% | +356.2% | |
| PE Ratio | - | – | – | – | – | |
| TTM Revenue | $740.64M | +43.7% | +864.2% | +100.0% | +100.0% | |
| TTM EPS | -$13.01 | -1.3% | +48.1% | +18.8% | -17.5% | |
| TTM Gross Profit | $704.02M | +42.2% | +862.4% | +10000.0% | +10000.0% | |
| Quarterly Operating Expenses | $382.76M | +52.8% | +117.4% | +376.7% | +552.4% |
TTM Operating Profit Highs
| Period | High | Date | Current |
|---|---|---|---|
| 1Y | -$307.49M | at high | |
| 3Y | -$293.57M | N/A | -4.7% |
| 5Y | -$206.67M | N/A | -48.8% |
| All | $93.48M | -428.9% |
TTM Operating Profit Lows
| Period | Low | Date | Current |
|---|---|---|---|
| 1Y | -$497.88M | N/A | +38.2% |
| 3Y | -$548.05M | +43.9% | |
| 5Y | -$548.05M | +43.9% | |
| All | -$548.05M | +43.9% |
TTM Operating Profit History
FAQ
What is the current TTM operating profit of MDGL?
As of today, MDGL TTM operating profit is -$307.49M
What is MDGL TTM operating profit most recent change?
MDGL TTM operating profit was up +0.75% on September 30, 2025
What is 1-year change in MDGL TTM operating profit?
MDGL TTM operating profit is up +43.90% year-over-year
How far is MDGL TTM operating profit from its all-time high?
MDGL TTM operating profit is currently -428.93% below its historical high of $93.48M set on March 31, 2010
How does MDGL TTM operating profit rank versus sector peers?
MDGL TTM operating profit is higher than 4.29% of companies in Healthcare sector
When is MDGL next earnings release?
The next earnings release for MDGL is on
Operating Profit Formula
Operating Profit = Gross Profit −
Data Sources & References
- MDGL Official Website www.madrigalpharma.com
- Most Recent Quarterly Report (10-Q) www.sec.gov/Archives/edgar/data/1157601/000162828025048559/0001628280-25-048559-index.htm
- Most Recent Annual Report (10-K) www.sec.gov/Archives/edgar/data/1157601/000162828025007980/0001628280-25-007980-index.htm
- MDGL Profile on Yahoo Finance finance.yahoo.com/quote/MDGL
- MDGL Profile on NASDAQ.com www.nasdaq.com/market-activity/stocks/mdgl