What is the current annual gross profit of ILMN?

As of today, ILMN annual gross profit is $2.96B

What is 1-year change in ILMN annual gross profit?

ILMN annual gross profit is up +3.56% year-over-year

What is 3-year change in ILMN annual gross profit?

ILMN annual gross profit is down -0.27% over the past 3 years

How far is ILMN annual gross profit from its all-time high?

ILMN annual gross profit is currently -6.02% below its historical high of $3.15B set on December 1, 2021

How does ILMN annual gross profit rank versus sector peers?

ILMN annual gross profit is higher than 94.92% of companies in Healthcare sector

When is ILMN next annual earnings release?

The next annual earnings release for ILMN is on February 4, 2027

What is the current quarterly gross profit of ILMN?

As of today, ILMN quarterly gross profit is $831.00M

What is ILMN quarterly gross profit most recent change?

ILMN quarterly gross profit was up +7.64% on September 27, 2026

What is 1-year change in ILMN quarterly gross profit?

ILMN quarterly gross profit is up +13.52% year-over-year

How far is ILMN quarterly gross profit from its all-time high?

ILMN quarterly gross profit is currently at its all-time high

How does ILMN quarterly gross profit rank versus sector peers?

ILMN quarterly gross profit is higher than 94.15% of companies in Healthcare sector

When is ILMN next earnings release?

The next earnings release for ILMN is on February 4, 2027

What is the current TTM gross profit of ILMN?

As of today, ILMN TTM gross profit is $3.10B

What is ILMN TTM gross profit most recent change?

ILMN TTM gross profit was up +3.30% on September 27, 2026

What is 1-year change in ILMN TTM gross profit?

ILMN TTM gross profit is up +8.39% year-over-year

How far is ILMN TTM gross profit from its all-time high?

ILMN TTM gross profit is currently -3.18% below its historical high of $3.20B set on March 31, 2022

How does ILMN TTM gross profit rank versus sector peers?

ILMN TTM gross profit is higher than 94.06% of companies in Healthcare sector

When is ILMN next earnings release?

The next earnings release for ILMN is on February 4, 2027

Illumina, Inc. (ILMN) Gross Profit History & Chart

Annual Gross Profit

$2.96B$102.00M+3.56%

December 31, 2025

Summary

Current Value: As of today, ILMN annual gross profit is $2.96B, up +3.56% on December 31, 2025
Historical Performance: ILMN annual gross profit is down -0.27% over the past 3 years, up +33.33% over the past 5 years
All-Time High Comparison: ILMN annual gross profit is currently -6.02% below its historical high of $3.15B set on December 1, 2021
3-Year Low Comparison: ILMN annual gross profit is +7.78% above its 3-year low of $2.75B reached on December 31, 2023
Sector Comparison: ILMN annual gross profit is higher than 94.92% of companies in Healthcare sector

Gross Profit Chart

beforeafter

Performance

ILMN Performance
Metric	Date	Value	1Y	3Y	5Y	15Y
Annual Gross Profit	Dec 31, 25	$2.96B	+3.6%	-0.3%	+33.3%	+373.0%
Quarterly Gross Profit	Sep 27, 26	$831.00M	+13.5%	+21.5%	+7.9%	+454.9%
TTM Gross Profit	Sep 27, 26	$3.10B	+8.4%	+13.1%	+4.6%	+336.0%
Price	Nov 11, 26	$212.93	+73.7%	+122.5%	-43.2%	+588.6%
Annual Revenue	Dec 31, 25	$4.34B	-0.4%	-5.4%	+33.9%	+380.5%
PE Ratio	Nov 11, 26	36.58	+33.2%	–	-40.7%	-7.7%
Annual EPS	Dec 31, 25	$5.45	+170.8%	+119.4%	+22.9%	+526.3%
	Dec 31, 25	$1.45B	-4.3%	-10.4%	+42.2%	+423.4%
Annual Gross Margin	Dec 31, 25	66.69%	+2.1%	+2.9%	-2.8%	-3.9%

Gross Profit Highs

ILMN Annual Gross Profit Highs Comparison
Period	High	Date	Current
3Y	$2.97B	N/A	-0.3%
5Y	$3.15B	Dec 1, 21	-6.0%
All	$3.15B	Dec 1, 21	-6.0%

Gross Profit Lows

ILMN Annual Gross Profit Lows Comparison
Period	Low	Date	Current
3Y	$2.75B	Dec 31, 23	+7.8%
5Y	$2.22B	N/A	+33.3%
All	$0.00	Dec 1, 98	N/A

Gross Profit History

Year	Value	Change
2025	$2.96B	+3.6%
2024	$2.86B	+4.1%
2023	$2.75B	-7.5%
2022	$2.97B	-5.8%
2021	$3.15B	+41.9%
2020	$2.22B	-9.9%
2019	$2.47B	+6.0%
2018	$2.33B	+24.4%
2017	$1.87B	+10.8%
2016	$1.69B	+7.0%
2015	$1.58B	+20.2%
2014	$1.31B	+35.1%
2013	$971.06M	+22.8%
2012	$790.81M	+8.9%

Year	Value	Change
2011	$726.38M	+15.9%
2010	$626.69M	+33.8%
2009	$468.49M	+26.5%
2008	$370.21M	+56.3%
2007	$236.87M	+89.1%
2006	$125.24M	+148.9%
2005	$50.32M	+34.8%
2004	$37.32M	+107.4%
2003	$18.00M	+812.2%
2002	$1.97M	+333.6%
2001	$455.00K	-45.9%
2000	$841.00K	>+9,900.0%
1999	$0.00	0.0%
1998	$0.00	-

FAQ

What is the current annual gross profit of ILMN?: As of today, ILMN annual gross profit is $2.96B
What is 1-year change in ILMN annual gross profit?: ILMN annual gross profit is up +3.56% year-over-year
What is 3-year change in ILMN annual gross profit?: ILMN annual gross profit is down -0.27% over the past 3 years
How far is ILMN annual gross profit from its all-time high?: ILMN annual gross profit is currently -6.02% below its historical high of $3.15B set on December 1, 2021
How does ILMN annual gross profit rank versus sector peers?: ILMN annual gross profit is higher than 94.92% of companies in Healthcare sector
When is ILMN next annual earnings release?: The next annual earnings release for ILMN is on February 4, 2027

Gross Profit Formula

Gross Profit = Revenue −

Quarterly Gross Profit

$831.00M$59.00M+7.64%

September 27, 2026

Summary

Current Value: As of today, ILMN quarterly gross profit is $831.00M, up +7.64% on September 27, 2026
Historical Performance: ILMN quarterly gross profit is up +13.52% year-over-year, up +21.49% over the past 3 years
All-Time High Comparison: ILMN quarterly gross profit is currently at its all-time high
3-Year Low Comparison: ILMN quarterly gross profit is +24.59% above its 3-year low of $667.00M reached on March 31, 2024
Sector Comparison: ILMN quarterly gross profit is higher than 94.15% of companies in Healthcare sector

Performance

ILMN Performance
Metric	Date	Value	3M	1Y	3Y	5Y
Quarterly Gross Profit	Sep 27, 26	$831.00M	+7.6%	+13.5%	+21.5%	+7.9%
Annual Gross Profit	Dec 31, 25	$2.96B	–	+3.6%	-0.3%	+33.3%
TTM Gross Profit	Sep 27, 26	$3.10B	+3.3%	+8.4%	+13.1%	+4.6%
Price	Nov 11, 26	$212.93	+10.4%	+73.7%	+122.5%	-43.2%
Quarterly Revenue	Sep 27, 26	$1.13B	-2.7%	+4.3%	+1.0%	+2.0%
PE Ratio	Nov 11, 26	36.58	+1.8%	+33.2%	–	-40.7%
Quarterly EPS	Sep 27, 26	$1.43	+5.6%	+46.7%	+129.9%	-31.1%
	Sep 27, 26	$299.00M	-23.1%	-14.8%	-31.3%	-11.5%
Quarterly Gross Margin	Sep 27, 26	73.54%	+10.6%	+8.8%	+20.3%	+5.8%

Quarterly Gross Profit Highs

ILMN Quarterly Gross Profit Highs Comparison
Period	High	Date	Current
1Y	$831.00M	Sep 27, 26	at high
3Y	$831.00M	Sep 27, 26	at high
5Y	$831.00M	Sep 27, 26	at high
All	$831.00M	Sep 27, 26	at high

Quarterly Gross Profit Lows

ILMN Quarterly Gross Profit Lows Comparison
Period	Low	Date	Current
1Y	$721.00M	Mar 29, 26	+15.3%
3Y	$667.00M	Mar 31, 24	+24.6%
5Y	$655.00M	Mar 31, 23	+26.9%
All	$0.00	Jun 30, 00	N/A

Quarterly Gross Profit History

Month	Value	Change
Sep 2026	$831.00M	+7.6%
Jun 2026	$772.00M	+7.1%
Mar 2026	$721.00M	-7.3%
Dec 2025	$778.00M	+6.3%
Sep 2025	$732.00M	+2.1%
Jun 2025	$717.00M	+4.7%
Mar 2025	$685.00M	-5.9%
Dec 2024	$728.00M	-2.3%
Sep 2024	$745.00M	+3.3%
Jun 2024	$721.00M	+8.1%
Mar 2024	$667.00M	-1.2%
Dec 2023	$675.00M	-1.3%
Sep 2023	$684.00M	-6.6%
Jun 2023	$732.00M	+11.8%
Mar 2023	$655.00M	-2.5%
Dec 2022	$672.00M	-6.3%
Sep 2022	$717.00M	-6.5%
Jun 2022	$767.00M	-5.9%
Mar 2022	$815.00M	-0.2%
Dec 2021	$817.00M	+6.1%
Sep 2021	$770.00M	-4.0%
Jun 2021	$802.00M	+5.0%
Mar 2021	$764.00M	+21.3%
Dec 2020	$630.00M	+19.8%
Sep 2020	$526.00M	+22.9%
Jun 2020	$428.00M	-30.9%
Mar 2020	$619.00M	-6.5%
Dec 2019	$662.00M	+1.7%
Sep 2019	$651.00M	+12.4%
Jun 2019	$579.00M	-1.4%
Mar 2019	$587.00M	-1.7%
Dec 2018	$597.00M	-1.3%
Sep 2018	$605.00M	+4.1%
Jun 2018	$581.00M	+6.8%
Mar 2018	$544.00M	-1.1%
Dec 2017	$550.00M	+12.5%
Sep 2017	$489.00M	+10.9%
Jun 2017	$441.00M	+13.1%
Mar 2017	$390.00M	-7.0%
Dec 2016	$419.44M	-2.5%
Sep 2016	$430.03M	-0.1%
Jun 2016	$430.48M	+6.6%
Mar 2016	$403.70M	-1.6%
Dec 2015	$410.36M	+4.0%
Sep 2015	$394.46M	+2.9%
Jun 2015	$383.29M	+0.4%
Mar 2015	$381.92M	+6.5%
Dec 2014	$358.74M	+3.7%
Sep 2014	$345.84M	+11.2%
Jun 2014	$311.06M	+7.9%
Mar 2014	$288.28M	+8.7%
Dec 2013	$265.15M	+10.7%
Sep 2013	$239.44M	+3.9%
Jun 2013	$230.51M	+4.6%

Month	Value	Change
Mar 2013	$220.29M	+8.2%
Dec 2012	$203.65M	+1.7%
Sep 2012	$200.16M	+1.7%
Jun 2012	$196.73M	+6.3%
Mar 2012	$185.12M	+8.5%
Dec 2011	$170.59M	+13.9%
Sep 2011	$149.77M	-25.4%
Jun 2011	$200.71M	+3.0%
Mar 2011	$194.80M	+17.3%
Dec 2010	$166.13M	+5.7%
Sep 2010	$157.15M	+7.6%
Jun 2010	$146.09M	+10.5%
Mar 2010	$132.18M	+5.3%
Dec 2009	$125.53M	+11.8%
Sep 2009	$112.25M	+0.8%
Jun 2009	$111.33M	-2.7%
Mar 2009	$114.48M	+10.5%
Dec 2008	$103.62M	+11.3%
Sep 2008	$93.13M	+2.8%
Jun 2008	$90.55M	+21.1%
Mar 2008	$74.77M	+4.1%
Dec 2007	$71.85M	+18.2%
Sep 2007	$60.78M	+13.1%
Jun 2007	$53.73M	+12.0%
Mar 2007	$47.99M	+19.0%
Dec 2006	$40.32M	+8.6%
Sep 2006	$37.12M	+32.6%
Jun 2006	$28.00M	+41.4%
Mar 2006	$19.81M	+25.7%
Dec 2005	$15.76M	+31.8%
Sep 2005	$11.96M	+7.8%
Jun 2005	$11.09M	+5.1%
Mar 2005	$10.55M	-3.3%
Dec 2004	$10.91M	+9.1%
Sep 2004	$10.00M	+18.7%
Jun 2004	$8.42M	+5.2%
Mar 2004	$8.00M	+9.3%
Dec 2003	$7.32M	+31.5%
Sep 2003	$5.57M	+103.0%
Jun 2003	$2.74M	+15.9%
Mar 2003	$2.37M	+5.2%
Dec 2002	$2.25M	+168.5%
Sep 2002	$838.00K	>+9,900.0%
Jun 2002	$0.00	0.0%
Mar 2002	$0.00	0.0%
Dec 2001	$0.00	0.0%
Sep 2001	$0.00	0.0%
Jun 2001	$0.00	0.0%
Mar 2001	$0.00	0.0%
Dec 2000	$0.00	0.0%
Sep 2000	$0.00	0.0%
Jun 2000	$0.00	-100.0%
Mar 2000	$44.00K	-

FAQ

What is the current quarterly gross profit of ILMN?: As of today, ILMN quarterly gross profit is $831.00M
What is ILMN quarterly gross profit most recent change?: ILMN quarterly gross profit was up +7.64% on September 27, 2026
What is 1-year change in ILMN quarterly gross profit?: ILMN quarterly gross profit is up +13.52% year-over-year
How far is ILMN quarterly gross profit from its all-time high?: ILMN quarterly gross profit is currently at its all-time high
How does ILMN quarterly gross profit rank versus sector peers?: ILMN quarterly gross profit is higher than 94.15% of companies in Healthcare sector
When is ILMN next earnings release?: The next earnings release for ILMN is on February 4, 2027

Gross Profit Formula

Gross Profit = Revenue −

TTM Gross Profit

$3.10B$99.00M+3.30%

September 27, 2026

Summary

Current Value: As of today, ILMN TTM gross profit is $3.10B, up +3.30% on September 27, 2026
Historical Performance: ILMN TTM gross profit is up +8.39% year-over-year, up +13.09% over the past 3 years
All-Time High Comparison: ILMN TTM gross profit is currently -3.18% below its historical high of $3.20B set on March 31, 2022
3-Year Low Comparison: ILMN TTM gross profit is +13.09% above its 3-year low of $2.74B reached on an earlier date
Sector Comparison: ILMN TTM gross profit is higher than 94.06% of companies in Healthcare sector

Performance

ILMN Performance
Metric	Date	Value	3M	1Y	3Y	5Y
TTM Gross Profit	Sep 27, 26	$3.10B	+3.3%	+8.4%	+13.1%	+4.6%
Annual Gross Profit	Dec 31, 25	$2.96B	–	+3.6%	-0.3%	+33.3%
Quarterly Gross Profit	Sep 27, 26	$831.00M	+7.6%	+13.5%	+21.5%	+7.9%
Price	Nov 11, 26	$212.93	+10.4%	+73.7%	+122.5%	-43.2%
TTM Revenue	Sep 27, 26	$4.54B	+1.1%	+6.0%	+1.7%	+6.1%
PE Ratio	Nov 11, 26	36.58	+1.8%	+33.2%	–	-40.7%
TTM EPS	Sep 27, 26	$5.82	+8.5%	+30.4%	+181.7%	-4.3%
	Sep 27, 26	$1.44B	-3.5%	+1.2%	-16.4%	+9.6%
Quarterly Gross Margin	Sep 27, 26	73.54%	+10.6%	+8.8%	+20.3%	+5.8%

TTM Gross Profit Highs

ILMN TTM Gross Profit Highs Comparison
Period	High	Date	Current
1Y	$3.10B	Sep 27, 26	at high
3Y	$3.10B	Sep 27, 26	at high
5Y	$3.20B	Mar 31, 22	-3.2%
All	$3.20B	Mar 31, 22	-3.2%

TTM Gross Profit Lows

ILMN TTM Gross Profit Lows Comparison
Period	Low	Date	Current
1Y	$2.86B	N/A	+8.4%
3Y	$2.74B	N/A	+13.1%
5Y	$2.74B	Sep 30, 23	+13.1%
All	$0.00	Mar 31, 01	N/A

TTM Gross Profit History

Month	Value	Change
Sep 2026	$3.10B	+3.3%
Jun 2026	$3.00B	+1.9%
Mar 2026	$2.95B	+1.2%
Dec 2025	$2.91B	+1.7%
Sep 2025	$2.86B	-0.5%
Jun 2025	$2.88B	-0.1%
Mar 2025	$2.88B	+0.6%
Dec 2024	$2.86B	+1.9%
Sep 2024	$2.81B	+2.2%
Jun 2024	$2.75B	-0.4%
Mar 2024	$2.76B	+0.4%
Dec 2023	$2.75B	+0.1%
Sep 2023	$2.74B	-1.2%
Jun 2023	$2.78B	-1.2%
Mar 2023	$2.81B	-5.4%
Dec 2022	$2.97B	-4.7%
Sep 2022	$3.12B	-1.7%
Jun 2022	$3.17B	-1.1%
Mar 2022	$3.20B	+1.6%
Dec 2021	$3.15B	+6.3%
Sep 2021	$2.97B	+9.0%
Jun 2021	$2.72B	+15.9%
Mar 2021	$2.35B	+6.6%
Dec 2020	$2.20B	-1.4%
Sep 2020	$2.24B	-5.3%
Jun 2020	$2.36B	-6.0%
Mar 2020	$2.51B	+1.3%
Dec 2019	$2.48B	+2.7%
Sep 2019	$2.41B	+1.9%
Jun 2019	$2.37B	-0.1%
Mar 2019	$2.37B	+1.8%
Dec 2018	$2.33B	+2.1%
Sep 2018	$2.28B	+5.4%
Jun 2018	$2.16B	+6.9%
Mar 2018	$2.02B	+8.2%
Dec 2017	$1.87B	+7.5%
Sep 2017	$1.74B	+3.5%
Jun 2017	$1.68B	+0.6%
Mar 2017	$1.67B	-0.8%
Dec 2016	$1.68B	+0.5%
Sep 2016	$1.67B	+2.2%
Jun 2016	$1.64B	+3.0%
Mar 2016	$1.59B	+1.4%
Dec 2015	$1.57B	+3.4%
Sep 2015	$1.52B	+3.3%
Jun 2015	$1.47B	+5.2%
Mar 2015	$1.40B	+7.2%
Dec 2014	$1.30B	+7.7%
Sep 2014	$1.21B	+9.6%
Jun 2014	$1.10B	+7.9%
Mar 2014	$1.02B	+7.1%
Dec 2013	$955.39M	+6.9%
Sep 2013	$893.89M	+4.6%
Jun 2013	$854.61M	+4.1%

Month	Value	Change
Mar 2013	$820.83M	+4.5%
Dec 2012	$785.66M	+4.4%
Sep 2012	$752.60M	+7.2%
Jun 2012	$702.21M	-0.6%
Mar 2012	$706.18M	-1.4%
Dec 2011	$715.86M	+0.6%
Sep 2011	$711.40M	-1.0%
Jun 2011	$718.78M	+8.2%
Mar 2011	$664.16M	+10.4%
Dec 2010	$601.54M	+7.2%
Sep 2010	$560.94M	+8.7%
Jun 2010	$516.04M	+7.2%
Mar 2010	$481.28M	+3.8%
Dec 2009	$463.58M	+5.0%
Sep 2009	$441.68M	+4.5%
Jun 2009	$422.56M	+5.2%
Mar 2009	$401.78M	+11.0%
Dec 2008	$362.07M	+9.6%
Sep 2008	$330.29M	+10.9%
Jun 2008	$297.94M	+14.1%
Mar 2008	$261.13M	+11.4%
Dec 2007	$234.34M	+15.5%
Sep 2007	$202.81M	+13.2%
Jun 2007	$179.15M	+16.8%
Mar 2007	$153.42M	+22.5%
Dec 2006	$125.24M	+24.4%
Sep 2006	$100.69M	+33.3%
Jun 2006	$75.53M	+28.8%
Mar 2006	$58.62M	+18.8%
Dec 2005	$49.36M	+10.9%
Sep 2005	$44.51M	+4.6%
Jun 2005	$42.54M	+6.7%
Mar 2005	$39.87M	+6.8%
Dec 2004	$37.32M	+10.6%
Sep 2004	$33.74M	+15.1%
Jun 2004	$29.31M	+24.0%
Mar 2004	$23.63M	+31.3%
Dec 2003	$18.00M	+39.2%
Sep 2003	$12.93M	+57.7%
Jun 2003	$8.20M	+50.3%
Mar 2003	$5.45M	+76.6%
Dec 2002	$3.09M	+268.5%
Sep 2002	$838.00K	>+9,900.0%
Jun 2002	$0.00	0.0%
Mar 2002	$0.00	0.0%
Dec 2001	$0.00	0.0%
Sep 2001	$0.00	0.0%
Jun 2001	$0.00	0.0%
Mar 2001	$0.00	-100.0%
Dec 2000	$44.00K	0.0%
Sep 2000	$44.00K	0.0%
Jun 2000	$44.00K	0.0%
Mar 2000	$44.00K	-

FAQ

What is the current TTM gross profit of ILMN?: As of today, ILMN TTM gross profit is $3.10B
What is ILMN TTM gross profit most recent change?: ILMN TTM gross profit was up +3.30% on September 27, 2026
What is 1-year change in ILMN TTM gross profit?: ILMN TTM gross profit is up +8.39% year-over-year
How far is ILMN TTM gross profit from its all-time high?: ILMN TTM gross profit is currently -3.18% below its historical high of $3.20B set on March 31, 2022
How does ILMN TTM gross profit rank versus sector peers?: ILMN TTM gross profit is higher than 94.06% of companies in Healthcare sector
When is ILMN next earnings release?: The next earnings release for ILMN is on February 4, 2027

Gross Profit Formula

Gross Profit = Revenue −

Data Sources & References

ILMN Official Website www.illumina.com
Most Recent Annual Report (10-K) www.sec.gov/Archives/edgar/data/1110803/000111080326000018/0001110803-26-000018-index.htm
ILMN Profile on Yahoo Finance finance.yahoo.com/quote/ILMN
ILMN Profile on NASDAQ.com www.nasdaq.com/market-activity/stocks/ilmn