What is the current annual gross margin of ILMN?

As of today, ILMN annual gross margin is 66.69%

What is 1-year change in ILMN annual gross margin?

ILMN annual gross margin is up +2.07% year-over-year

What is 3-year change in ILMN annual gross margin?

ILMN annual gross margin is up +2.87% over the past 3 years

How far is ILMN annual gross margin from its all-time high?

ILMN annual gross margin is currently -9.62% below its historical high of 73.79% set on December 1, 2004

How does ILMN annual gross margin rank versus sector peers?

ILMN annual gross margin is higher than 64.82% of companies in Healthcare sector

When is ILMN next annual earnings release?

The next annual earnings release for ILMN is on February 4, 2027

What is the current quarterly gross margin of ILMN?

As of today, ILMN quarterly gross margin is 73.54%

What is ILMN quarterly gross margin most recent change?

ILMN quarterly gross margin was up +10.60% on September 27, 2026

What is 1-year change in ILMN quarterly gross margin?

ILMN quarterly gross margin is up +8.80% year-over-year

How far is ILMN quarterly gross margin from its all-time high?

ILMN quarterly gross margin is currently -0.70% below its historical high of 74.06% set on March 28, 2004

How does ILMN quarterly gross margin rank versus sector peers?

ILMN quarterly gross margin is higher than 70.55% of companies in Healthcare sector

When is ILMN next earnings release?

The next earnings release for ILMN is on February 4, 2027

Illumina, Inc. (ILMN) Gross Margin History & Chart

Annual Gross Margin

66.69%1.35%+2.07%

December 31, 2025

Summary

Current Value: As of today, ILMN annual gross margin is 66.69%, up +2.07% on December 31, 2025
Historical Performance: ILMN annual gross margin is up +2.87% over the past 3 years, down -2.83% over the past 5 years
All-Time High Comparison: ILMN annual gross margin is currently -9.62% below its historical high of 73.79% set on December 1, 2004
3-Year Low Comparison: ILMN annual gross margin is +9.22% above its 3-year low of 61.06% reached on December 31, 2023
Sector Comparison: ILMN annual gross margin is higher than 64.82% of companies in Healthcare sector

Gross Margin Chart

beforeafter

Performance

ILMN Performance
Metric	Date	Value	1Y	3Y	5Y	15Y
Annual Gross Margin	Dec 31, 25	66.69%	+2.1%	+2.9%	-2.8%	-3.9%
Quarterly Gross Margin	Sep 27, 26	73.54%	+8.8%	+20.3%	+5.8%	+15.6%
Price	Nov 11, 26	$212.93	+73.7%	+122.5%	-43.2%	+588.6%
PE Ratio	Nov 11, 26	36.58	+33.2%	–	-40.7%	-7.7%
Annual Revenue	Dec 31, 25	$4.34B	-0.4%	-5.4%	+33.9%	+380.5%
Annual Gross Profit	Dec 31, 25	$2.96B	+3.6%	-0.3%	+33.3%	+373.0%
Annual Operating Margin	Dec 31, 25	19.92%	+125.3%	+158.0%	+11.2%	-11.2%
Annual Net Margin	Dec 31, 25	19.59%	+169.8%	+120.4%	-3.3%	+41.6%

Gross Margin Highs

ILMN Annual Gross Margin Highs Comparison
Period	High	Date	Current
3Y	66.69%	Dec 31, 25	at high
5Y	69.69%	Dec 1, 21	-4.3%
All	73.79%	Dec 1, 04	-9.6%

Gross Margin Lows

ILMN Annual Gross Margin Lows Comparison
Period	Low	Date	Current
3Y	61.06%	Dec 31, 23	+9.2%
5Y	61.06%	Dec 31, 23	+9.2%
All	0.00%	Dec 31, 99	N/A

Gross Margin History

Year	Value	Change
2025	66.69%	+2.1%
2024	65.34%	+7.0%
2023	61.06%	-5.8%
2022	64.83%	-7.0%
2021	69.69%	+1.5%
2020	68.63%	-1.4%
2019	69.63%	-0.3%
2018	69.82%	+2.8%
2017	67.95%	-3.4%
2016	70.37%	-0.9%
2015	71.04%	+0.8%
2014	70.46%	+3.1%
2013	68.33%	-0.8%
2012	68.85%	+0.0%

Year	Value	Change
2011	68.82%	-0.9%
2010	69.42%	-1.3%
2009	70.31%	+8.9%
2008	64.58%	0.0%
2007	64.58%	-4.8%
2006	67.85%	-0.9%
2005	68.46%	-7.2%
2004	73.79%	+14.9%
2003	64.20%	+226.7%
2002	19.65%	+7.4%
2001	18.30%	-71.5%
2000	64.25%	>+9,900.0%
1999	0.00%	-

FAQ

What is the current annual gross margin of ILMN?: As of today, ILMN annual gross margin is 66.69%
What is 1-year change in ILMN annual gross margin?: ILMN annual gross margin is up +2.07% year-over-year
What is 3-year change in ILMN annual gross margin?: ILMN annual gross margin is up +2.87% over the past 3 years
How far is ILMN annual gross margin from its all-time high?: ILMN annual gross margin is currently -9.62% below its historical high of 73.79% set on December 1, 2004
How does ILMN annual gross margin rank versus sector peers?: ILMN annual gross margin is higher than 64.82% of companies in Healthcare sector
When is ILMN next annual earnings release?: The next annual earnings release for ILMN is on February 4, 2027

Gross Margin Formula

Gross Margin = Gross Profit

Revenue × 100%

Quarterly Gross Margin

73.54%7.05%+10.60%

September 27, 2026

Summary

Current Value: As of today, ILMN quarterly gross margin is 73.54%, up +10.60% on September 27, 2026
Historical Performance: ILMN quarterly gross margin is up +8.80% year-over-year, up +20.30% over the past 3 years
All-Time High Comparison: ILMN quarterly gross margin is currently -0.70% below its historical high of 74.06% set on March 28, 2004
3-Year Low Comparison: ILMN quarterly gross margin is +22.24% above its 3-year low of 60.16% reached on December 31, 2023
Sector Comparison: ILMN quarterly gross margin is higher than 70.55% of companies in Healthcare sector

Performance

ILMN Performance
Metric	Date	Value	3M	1Y	3Y	5Y
Quarterly Gross Margin	Sep 27, 26	73.54%	+10.6%	+8.8%	+20.3%	+5.8%
Annual Gross Margin	Dec 31, 25	66.69%	–	+2.1%	+2.9%	-2.8%
Price	Nov 11, 26	$212.93	+10.4%	+73.7%	+122.5%	-43.2%
PE Ratio	Nov 11, 26	36.58	+1.8%	+33.2%	–	-40.7%
Quarterly Revenue	Sep 27, 26	$1.13B	-2.7%	+4.3%	+1.0%	+2.0%
Quarterly Gross Profit	Sep 27, 26	$831.00M	+7.6%	+13.5%	+21.5%	+7.9%
Quarterly Operating Margin	Sep 27, 26	24.69%	+35.9%	+15.8%	+318.5%	+150.2%
Quarterly Net Margin	Sep 27, 26	19.47%	+9.2%	+40.6%	+128.9%	-31.9%

Quarterly Gross Margin Highs

ILMN Quarterly Gross Margin Highs Comparison
Period	High	Date	Current
1Y	73.54%	Sep 27, 26	at high
3Y	73.54%	Sep 27, 26	at high
5Y	73.54%	Sep 27, 26	at high
All	74.06%	Mar 28, 04	-0.7%

Quarterly Gross Margin Lows

ILMN Quarterly Gross Margin Lows Comparison
Period	Low	Date	Current
1Y	66.09%	Mar 29, 26	+11.3%
3Y	60.16%	Dec 31, 23	+22.2%
5Y	60.16%	Dec 31, 23	+22.2%
All	0.00%	Jun 30, 00	N/A

Quarterly Gross Margin History

Month	Value	Change
Sep 2026	73.54%	+10.6%
Jun 2026	66.49%	+0.6%
Mar 2026	66.09%	-1.5%
Dec 2025	67.07%	-0.8%
Sep 2025	67.59%	-0.4%
Jun 2025	67.83%	+3.1%
Mar 2025	65.80%	-0.2%
Dec 2024	65.94%	-4.4%
Sep 2024	68.98%	+6.4%
Jun 2024	64.84%	+4.6%
Mar 2024	61.99%	+3.0%
Dec 2023	60.16%	-1.6%
Sep 2023	61.13%	-1.8%
Jun 2023	62.24%	+3.3%
Mar 2023	60.26%	-2.9%
Dec 2022	62.05%	-3.5%
Sep 2022	64.30%	-2.6%
Jun 2022	66.01%	-0.9%
Mar 2022	66.64%	-2.3%
Dec 2021	68.20%	-1.9%
Sep 2021	69.49%	-2.4%
Jun 2021	71.23%	+1.9%
Mar 2021	69.90%	+5.7%
Dec 2020	66.11%	-0.2%
Sep 2020	66.25%	-2.0%
Jun 2020	67.61%	-6.2%
Mar 2020	72.06%	+3.7%
Dec 2019	69.46%	-3.2%
Sep 2019	71.78%	+3.9%
Jun 2019	69.09%	-0.4%
Mar 2019	69.39%	+0.8%
Dec 2018	68.86%	-2.9%
Sep 2018	70.93%	+1.3%
Jun 2018	70.00%	+0.6%
Mar 2018	69.57%	-1.6%
Dec 2017	70.69%	+3.2%
Sep 2017	68.49%	+2.8%
Jun 2017	66.62%	+2.1%
Mar 2017	65.22%	-3.7%
Dec 2016	67.72%	-4.4%
Sep 2016	70.83%	-1.3%
Jun 2016	71.73%	+1.6%
Mar 2016	70.61%	+1.8%
Dec 2015	69.37%	-3.2%
Sep 2015	71.68%	+0.9%
Jun 2015	71.06%	+0.2%
Mar 2015	70.92%	+1.3%
Dec 2014	70.01%	-2.7%
Sep 2014	71.96%	+3.5%
Jun 2014	69.50%	+1.4%
Mar 2014	68.51%	+0.1%
Dec 2013	68.46%	+2.0%
Sep 2013	67.11%	+0.8%
Jun 2013	66.60%	+0.1%

Month	Value	Change
Mar 2013	66.56%	+1.1%
Dec 2012	65.85%	-6.0%
Sep 2012	70.02%	-0.1%
Jun 2012	70.11%	+3.3%
Mar 2012	67.87%	-0.5%
Dec 2011	68.22%	+7.3%
Sep 2011	63.60%	-8.9%
Jun 2011	69.82%	+1.3%
Mar 2011	68.95%	+8.4%
Dec 2010	63.58%	-4.0%
Sep 2010	66.22%	-3.9%
Jun 2010	68.91%	+0.2%
Mar 2010	68.80%	-1.0%
Dec 2009	69.52%	-1.9%
Sep 2009	70.88%	+2.9%
Jun 2009	68.87%	-0.3%
Mar 2009	69.06%	+7.3%
Dec 2008	64.39%	+3.9%
Sep 2008	61.98%	-4.1%
Jun 2008	64.60%	+5.3%
Mar 2008	61.36%	-3.8%
Dec 2007	63.80%	+2.4%
Sep 2007	62.33%	-1.9%
Jun 2007	63.56%	-4.4%
Mar 2007	66.51%	-0.3%
Dec 2006	66.71%	-3.9%
Sep 2006	69.41%	+3.1%
Jun 2006	67.35%	-1.1%
Mar 2006	68.07%	-0.6%
Dec 2005	68.50%	+11.8%
Sep 2005	61.27%	-12.6%
Jun 2005	70.08%	+0.6%
Mar 2005	69.64%	-5.6%
Dec 2004	73.80%	-0.2%
Sep 2004	73.97%	+0.9%
Jun 2004	73.30%	-1.0%
Mar 2004	74.06%	+8.7%
Dec 2003	68.16%	+1.0%
Sep 2003	67.50%	+17.4%
Jun 2003	57.52%	+4.0%
Mar 2003	55.33%	-4.4%
Dec 2002	57.90%	+106.3%
Sep 2002	28.07%	>+9,900.0%
Jun 2002	0.00%	0.0%
Mar 2002	0.00%	0.0%
Dec 2001	0.00%	0.0%
Sep 2001	0.00%	0.0%
Jun 2001	0.00%	0.0%
Mar 2001	0.00%	0.0%
Dec 2000	0.00%	0.0%
Sep 2000	0.00%	0.0%
Jun 2000	0.00%	-100.0%
Mar 2000	52.88%	-

FAQ

What is the current quarterly gross margin of ILMN?: As of today, ILMN quarterly gross margin is 73.54%
What is ILMN quarterly gross margin most recent change?: ILMN quarterly gross margin was up +10.60% on September 27, 2026
What is 1-year change in ILMN quarterly gross margin?: ILMN quarterly gross margin is up +8.80% year-over-year
How far is ILMN quarterly gross margin from its all-time high?: ILMN quarterly gross margin is currently -0.70% below its historical high of 74.06% set on March 28, 2004
How does ILMN quarterly gross margin rank versus sector peers?: ILMN quarterly gross margin is higher than 70.55% of companies in Healthcare sector
When is ILMN next earnings release?: The next earnings release for ILMN is on February 4, 2027

Gross Margin Formula

Gross Margin = Gross Profit

Revenue × 100%

Data Sources & References

ILMN Official Website www.illumina.com
Most Recent Annual Report (10-K) www.sec.gov/Archives/edgar/data/1110803/000111080326000018/0001110803-26-000018-index.htm
ILMN Profile on Yahoo Finance finance.yahoo.com/quote/ILMN
ILMN Profile on NASDAQ.com www.nasdaq.com/market-activity/stocks/ilmn