What is the current annual operating margin of REGN?

As of today, REGN annual operating margin is 25.75%

What is 1-year change in REGN annual operating margin?

REGN annual operating margin is down -12.39% year-over-year

What is 3-year change in REGN annual operating margin?

REGN annual operating margin is down -41.79% over the past 3 years

How far is REGN annual operating margin from its all-time high?

REGN annual operating margin is currently -53.75% below its historical high of 55.67% set on December 31, 2021

How does REGN annual operating margin rank versus sector peers?

REGN annual operating margin is higher than 92.82% of companies in Healthcare sector

When is REGN next annual earnings release?

The next annual earnings release for REGN is on January 28, 2027

What is the current quarterly operating margin of REGN?

As of today, REGN quarterly operating margin is 40.46%

What is REGN quarterly operating margin most recent change?

REGN quarterly operating margin was up +22.20% on September 30, 2026

What is 1-year change in REGN quarterly operating margin?

REGN quarterly operating margin is up +36.87% year-over-year

How far is REGN quarterly operating margin from its all-time high?

REGN quarterly operating margin is currently -37.89% below its historical high of 65.14% set on June 30, 2021

How does REGN quarterly operating margin rank versus sector peers?

REGN quarterly operating margin is higher than 95.85% of companies in Healthcare sector

When is REGN next earnings release?

The next earnings release for REGN is on January 28, 2027

REGN Operating Margin History & Chart Since 1990

Annual Operating Margin

25.75%3.64%-12.39%

December 31, 2025

Summary

Current Value: As of today, REGN annual operating margin is 25.75%, down -12.39% on December 31, 2025
Historical Performance: REGN annual operating margin is down -41.79% over the past 3 years, down -38.82% over the past 5 years
All-Time High Comparison: REGN annual operating margin is currently -53.75% below its historical high of 55.67% set on December 31, 2021
3-Year Low Comparison: REGN annual operating margin is at its 3-year low
Sector Comparison: REGN annual operating margin is higher than 92.82% of companies in Healthcare sector

Operating Margin Chart

beforeafter

Performance

REGN Performance
Metric	Date	Value	1Y	3Y	5Y	15Y
Annual Operating Margin	Dec 31, 25	25.75%	-12.4%	-41.8%	-38.8%	+221.3%
Quarterly Operating Margin	Sep 30, 26	40.46%	+36.9%	+12.4%	-24.4%	+171.2%
Price	Oct 30, 26	$927.89	+41.9%	+19.3%	+45.0%	+1567.1%
PE Ratio	Oct 30, 26	20.48	+30.8%	-7.7%	+100.4%	–
Annual Revenue	Dec 31, 25	$14.34B	+1.0%	+17.8%	+68.8%	+3024.3%
Annual Operating Profit	Dec 31, 25	$3.69B	-11.5%	-31.4%	+3.3%	+3888.6%
Annual Gross Margin	Dec 31, 25	86.27%	+4.3%	+0.3%	+2.6%	-9.4%
Annual Net Margin	Dec 31, 25	31.41%	+1.1%	-11.9%	-24.0%	+238.0%

Operating Margin Highs

REGN Annual Operating Margin Highs Comparison
Period	High	Date	Current
3Y	44.24%	N/A	-41.8%
5Y	55.67%	Dec 31, 21	-53.8%
All	55.67%	Dec 31, 21	-53.8%

Operating Margin Lows

REGN Annual Operating Margin Lows Comparison
Period	Low	Date	Current
3Y	25.75%	Dec 31, 25	at low
5Y	25.75%	Dec 31, 25	at low
All	-554.76%	Dec 31, 02	+104.6%

Operating Margin History

Year	Value	Change
2025	25.75%	-12.4%
2024	29.39%	-11.3%
2023	33.15%	-25.1%
2022	44.24%	-20.5%
2021	55.67%	+32.3%
2020	42.09%	+24.9%
2019	33.70%	-10.8%
2018	37.77%	+6.7%
2017	35.41%	+29.3%
2016	27.38%	-10.3%
2015	30.51%	+2.6%
2014	29.74%	-17.7%
2013	36.13%	+8.1%
2012	33.41%	+172.6%
2011	-46.02%	-116.8%
2010	-21.23%	-8.6%
2009	-19.54%	+48.1%
2008	-37.67%	+58.9%

Year	Value	Change
2007	-91.55%	+45.9%
2006	-169.13%	+8.4%
2005	-184.62%	-5,798.1%
2004	3.24%	+101.9%
2003	-173.90%	+68.7%
2002	-554.76%	-42.3%
2001	-389.95%	-814.5%
2000	-42.64%	+38.3%
1999	-69.09%	-110.5%
1998	-32.82%	+35.6%
1997	-50.95%	+53.4%
1996	-109.32%	-152.2%
1995	-43.35%	+59.5%
1994	-106.97%	+80.4%
1993	-546.92%	-53.4%
1992	-356.43%	-172.2%
1991	-130.93%	-98.4%
1990	-66.00%	-

FAQ

What is the current annual operating margin of REGN?: As of today, REGN annual operating margin is 25.75%
What is 1-year change in REGN annual operating margin?: REGN annual operating margin is down -12.39% year-over-year
What is 3-year change in REGN annual operating margin?: REGN annual operating margin is down -41.79% over the past 3 years
How far is REGN annual operating margin from its all-time high?: REGN annual operating margin is currently -53.75% below its historical high of 55.67% set on December 31, 2021
How does REGN annual operating margin rank versus sector peers?: REGN annual operating margin is higher than 92.82% of companies in Healthcare sector
When is REGN next annual earnings release?: The next annual earnings release for REGN is on January 28, 2027

Operating Margin Formula

Operating Profit Margin = Operating Income

Revenue × 100%

Quarterly Operating Margin

40.46%7.35%+22.20%

September 30, 2026

Summary

Current Value: As of today, REGN quarterly operating margin is 40.46%, up +22.20% on September 30, 2026
Historical Performance: REGN quarterly operating margin is up +36.87% year-over-year, up +12.36% over the past 3 years
All-Time High Comparison: REGN quarterly operating margin is currently -37.89% below its historical high of 65.14% set on June 30, 2021
3-Year Low Comparison: REGN quarterly operating margin is +102.91% above its 3-year low of 19.94% reached on March 31, 2025
Sector Comparison: REGN quarterly operating margin is higher than 95.85% of companies in Healthcare sector

Performance

REGN Performance
Metric	Date	Value	3M	1Y	3Y	5Y
Quarterly Operating Margin	Sep 30, 26	40.46%	+22.2%	+36.9%	+12.4%	-24.4%
Annual Operating Margin	Dec 31, 25	25.75%	–	-12.4%	-41.8%	-38.8%
Price	Oct 30, 26	$927.89	+25.7%	+41.9%	+19.3%	+45.0%
PE Ratio	Oct 30, 26	20.48	+12.2%	+30.8%	-7.7%	+100.4%
Quarterly Revenue	Sep 30, 26	$5.12B	+19.2%	+36.3%	+52.1%	+48.2%
Quarterly Operating Profit	Sep 30, 26	$2.07B	+45.7%	+86.5%	+70.9%	+12.1%
Quarterly Gross Margin	Sep 30, 26	86.42%	+3.3%	+4.8%	+3.0%	+2.0%
Quarterly Net Margin	Sep 30, 26	38.09%	+26.0%	-2.1%	+27.1%	-19.4%

Quarterly Operating Margin Highs

REGN Quarterly Operating Margin Highs Comparison
Period	High	Date	Current
1Y	40.46%	Sep 30, 26	at high
3Y	40.46%	Sep 30, 26	at high
5Y	53.50%	N/A	-24.4%
All	65.14%	Jun 30, 21	-37.9%

Quarterly Operating Margin Lows

REGN Quarterly Operating Margin Lows Comparison
Period	Low	Date	Current
1Y	20.66%	Mar 31, 26	+95.8%
3Y	19.94%	Mar 31, 25	+102.9%
5Y	19.94%	Mar 31, 25	+102.9%
All	-753.85%	Jun 30, 93	+105.4%

Quarterly Operating Margin History

Month	Value	Change
Sep 2026	40.46%	+22.2%
Jun 2026	33.11%	+60.3%
Mar 2026	20.66%	-10.7%
Dec 2025	23.13%	-21.8%
Sep 2025	29.56%	-0.3%
Jun 2025	29.64%	+48.6%
Mar 2025	19.94%	-26.4%
Dec 2024	27.09%	-18.4%
Sep 2024	33.21%	+7.7%
Jun 2024	30.83%	+27.8%
Mar 2024	24.12%	-21.2%
Dec 2023	30.59%	-15.1%
Sep 2023	36.01%	+11.9%
Jun 2023	32.19%	+1.5%
Mar 2023	31.71%	-17.7%
Dec 2022	38.53%	-7.6%
Sep 2022	41.68%	-8.9%
Jun 2022	45.74%	+5.4%
Mar 2022	43.39%	-18.6%
Dec 2021	53.31%	-0.4%
Sep 2021	53.50%	-17.9%
Jun 2021	65.14%	+48.0%
Mar 2021	44.00%	-8.7%
Dec 2020	48.17%	+4.9%
Sep 2020	45.91%	+36.5%
Jun 2020	33.63%	-12.2%
Mar 2020	38.29%	+5.6%
Dec 2019	36.26%	-14.4%
Sep 2019	42.35%	+111.8%
Jun 2019	20.00%	-42.8%
Mar 2019	34.97%	-6.1%
Dec 2018	37.25%	-1.2%
Sep 2018	37.69%	-2.6%
Jun 2018	38.69%	+3.1%
Mar 2018	37.53%	+10.2%
Dec 2017	34.05%	-8.7%
Sep 2017	37.31%	-0.3%
Jun 2017	37.43%	+14.7%
Mar 2017	32.64%	+15.4%
Dec 2016	28.28%	-4.9%
Sep 2016	29.73%	+23.6%
Jun 2016	24.05%	-12.3%
Mar 2016	27.42%	+30.3%
Dec 2015	21.04%	-39.0%
Sep 2015	34.50%	-0.1%
Jun 2015	34.53%	+5.9%
Mar 2015	32.61%	+5.8%
Dec 2014	30.83%	+22.4%
Sep 2014	25.18%	-24.6%
Jun 2014	33.41%	+12.4%
Mar 2014	29.72%	-14.5%
Dec 2013	34.74%	-12.4%
Sep 2013	39.66%	+14.8%
Jun 2013	34.55%	-0.7%
Mar 2013	34.81%	-1.0%
Dec 2012	35.16%	-26.1%
Sep 2012	47.60%	+62.8%
Jun 2012	29.23%	+205.1%
Mar 2012	9.58%	+125.9%
Dec 2011	-36.92%	+35.1%
Sep 2011	-56.85%	-1.6%
Jun 2011	-55.95%	-53.2%
Mar 2011	-36.52%	-282.0%
Dec 2010	-9.56%	+68.4%
Sep 2010	-30.28%	-47.9%
Jun 2010	-20.47%	+26.0%
Mar 2010	-27.68%	+32.0%
Dec 2009	-40.71%	-3,600.9%
Sep 2009	-1.10%	+93.9%
Jun 2009	-18.07%	+21.0%
Mar 2009	-22.86%	+63.1%

Month	Value	Change
Dec 2008	-61.96%	-103.9%
Sep 2008	-30.39%	+4.9%
Jun 2008	-31.97%	-13.3%
Mar 2008	-28.22%	-58.4%
Dec 2007	-17.82%	+89.7%
Sep 2007	-173.31%	-25.7%
Jun 2007	-137.89%	+35.3%
Mar 2007	-213.13%	+34.1%
Dec 2006	-323.56%	-78.7%
Sep 2006	-181.10%	-45.0%
Jun 2006	-124.86%	-5.9%
Mar 2006	-117.95%	+24.8%
Dec 2005	-156.76%	+26.2%
Sep 2005	-212.34%	-8.0%
Jun 2005	-196.55%	-12.4%
Mar 2005	-174.84%	-2,171.6%
Dec 2004	8.44%	+132.5%
Sep 2004	-25.96%	+41.6%
Jun 2004	-44.49%	-215.9%
Mar 2004	38.38%	+147.6%
Dec 2003	-80.57%	+45.5%
Sep 2003	-147.79%	+42.2%
Jun 2003	-255.72%	+8.7%
Mar 2003	-279.98%	+60.3%
Dec 2002	-705.64%	-39.7%
Sep 2002	-505.27%	+6.0%
Jun 2002	-537.80%	-5.5%
Mar 2002	-509.88%	+24.2%
Dec 2001	-672.42%	-58.2%
Sep 2001	-425.07%	-35.8%
Jun 2001	-312.94%	-34.3%
Mar 2001	-233.03%	-189.5%
Sep 2000	-80.49%	-192.7%
Jun 2000	-27.50%	+60.0%
Mar 2000	-68.67%	-241.5%
Dec 1999	-20.11%	+53.1%
Sep 1999	-42.92%	+60.3%
Jun 1999	-108.12%	+29.5%
Mar 1999	-153.29%	-18.2%
Dec 1998	-129.70%	-984.4%
Sep 1998	-11.96%	-189.4%
Jun 1998	13.38%	+129.8%
Mar 1998	-44.95%	+53.3%
Dec 1997	-96.15%	-677.9%
Sep 1997	-12.36%	+78.0%
Jun 1997	-56.06%	+15.2%
Mar 1997	-66.13%	+4.5%
Dec 1996	-69.23%	+2.5%
Sep 1996	-70.97%	-18.9%
Jun 1996	-59.68%	+34.0%
Mar 1996	-90.38%	-94.2%
Dec 1995	-46.55%	-20.3%
Sep 1995	-38.71%	-126.2%
Jun 1995	-17.11%	+43.8%
Mar 1995	-30.43%	+54.1%
Dec 1994	-66.23%	-59.3%
Sep 1994	-41.57%	+85.0%
Jun 1994	-277.78%	+19.9%
Mar 1994	-346.67%	+10.2%
Dec 1993	-386.21%	-49.5%
Sep 1993	-258.33%	+65.7%
Jun 1993	-753.85%	-72.1%
Mar 1993	-438.10%	-65.2%
Dec 1992	-265.22%	-13.7%
Sep 1992	-233.33%	-113.3%
Jun 1992	-109.38%	-19.6%
Mar 1992	-91.43%	+50.6%
Dec 1991	-185.00%	-40.6%
Sep 1991	-131.58%	-11.8%
Jun 1991	-117.65%	+78.2%
Dec 1990	-538.46%	-

FAQ

What is the current quarterly operating margin of REGN?: As of today, REGN quarterly operating margin is 40.46%
What is REGN quarterly operating margin most recent change?: REGN quarterly operating margin was up +22.20% on September 30, 2026
What is 1-year change in REGN quarterly operating margin?: REGN quarterly operating margin is up +36.87% year-over-year
How far is REGN quarterly operating margin from its all-time high?: REGN quarterly operating margin is currently -37.89% below its historical high of 65.14% set on June 30, 2021
How does REGN quarterly operating margin rank versus sector peers?: REGN quarterly operating margin is higher than 95.85% of companies in Healthcare sector
When is REGN next earnings release?: The next earnings release for REGN is on January 28, 2027

Operating Margin Formula

Operating Profit Margin = Operating Income

Revenue × 100%

Data Sources & References

REGN Official Website www.regeneron.com
Most Recent Annual Report (10-K) www.sec.gov/Archives/edgar/data/872589/000087258926000008/0000872589-26-000008-index.htm
REGN Profile on Yahoo Finance finance.yahoo.com/quote/REGN
REGN Profile on NASDAQ.com www.nasdaq.com/market-activity/stocks/regn