Annual Operating Profit
-$786.57M$105.64M-15.51%
Summary
- Current Value
- As of today, INSM annual operating profit is -$786.57M, down -15.51% on
- Historical Performance
- INSM annual operating profit is down -113.88% over the past 3 years, and down -234.36% over the past 5 years
- All-Time High Comparison
- INSM annual operating profit is currently -9620.34% below its historical high of -$8.09M set on
- 3-Year Low Comparison
- INSM annual operating profit is at its 3-year low
- Sector Comparison
- INSM annual operating profit is higher than 0.34% of companies in Healthcare sector
Operating Profit Chart
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Series
SUGGESTED SERIES
Performance
| Metric | Date | Value | 1Y | 3Y | 5Y | 15Y |
|---|---|---|---|---|---|---|
| Annual Operating Profit | -$786.57M | -15.5% | -113.9% | -234.4% | -8968.1% | |
| Quarterly Operating Profit | -$261.35M | -31.5% | -113.4% | -364.9% | -10000.0% | |
| TTM Operating Profit | -$990.28M | -40.7% | -133.1% | -354.7% | -10000.0% | |
| Price | $177.12 | +153.2% | +786.5% | +432.1% | +2711.4% | |
| PE Ratio | - | – | – | – | – | |
| Annual Revenue | $363.71M | +19.2% | +93.0% | +166.5% | +3406.3% | |
| Annual EPS | -$5.57 | -4.4% | -43.7% | -85.2% | -159.9% | |
| Annual Gross Profit | $272.91M | +16.3% | +96.0% | +154.4% | +2723.4% | |
| Annual Operating Expenses | $1.06B | +15.6% | +107.9% | +206.3% | +5489.0% |
Operating Profit Highs
| Period | High | Date | Current |
|---|---|---|---|
| 3Y | -$478.12M | N/A | -64.5% |
| 5Y | -$265.23M | N/A | -196.6% |
| All | -$8.09M | -9620.3% |
Operating Profit Lows
| Period | Low | Date | Current |
|---|---|---|---|
| 3Y | -$786.57M | at low | |
| 5Y | -$786.57M | at low | |
| All | -$786.57M | at low |
Operating Profit History
FAQ
What is the current annual operating profit of INSM?
As of today, INSM annual operating profit is -$786.57M
What is 1-year change in INSM annual operating profit?
INSM annual operating profit is down -15.51% year-over-year
What is 3-year change in INSM annual operating profit?
INSM annual operating profit is down -113.88% over the past 3 years
How far is INSM annual operating profit from its all-time high?
INSM annual operating profit is currently -9620.34% below its historical high of -$8.09M set on December 31, 2010
How does INSM annual operating profit rank versus sector peers?
INSM annual operating profit is higher than 0.34% of companies in Healthcare sector
When is INSM next annual earnings release?
The next annual earnings release for INSM is on
Quarterly Operating Profit
-$261.35M$7.48M-2.94%
Summary
- Current Value
- As of today, INSM quarterly operating profit is -$261.35M, down -2.94% on
- Historical Performance
- INSM quarterly operating profit is down -31.50% year-over-year, and down -113.42% over the past 3 years
- All-Time High Comparison
- INSM quarterly operating profit is currently -76295.92% below its historical high of $343.00K set on
- 3-Year Low Comparison
- INSM quarterly operating profit is at its 3-year low
- Sector Comparison
- INSM quarterly operating profit is higher than 0.27% of companies in Healthcare sector
Performance
| Metric | Date | Value | 3M | 1Y | 3Y | 5Y |
|---|---|---|---|---|---|---|
| Quarterly Operating Profit | -$261.35M | -2.9% | -31.5% | -113.4% | -364.9% | |
| Annual Operating Profit | -$786.57M | – | -15.5% | -113.9% | -234.4% | |
| TTM Operating Profit | -$990.28M | -6.8% | -40.7% | -133.1% | -354.7% | |
| Price | $177.12 | +15.9% | +153.2% | +786.5% | +432.1% | |
| PE Ratio | - | – | – | – | – | |
| Quarterly Revenue | $142.34M | +32.5% | +52.4% | +110.2% | +226.2% | |
| Quarterly EPS | -$1.75 | -2.8% | -37.7% | -61.0% | -178.9% | |
| Quarterly Gross Profit | $111.44M | +42.7% | +57.0% | +110.3% | +250.7% | |
| Quarterly Operating Expenses | $372.79M | +12.3% | +38.2% | +112.5% | +323.6% |
Quarterly Operating Profit Highs
| Period | High | Date | Current |
|---|---|---|---|
| 1Y | -$229.84M | -13.7% | |
| 3Y | -$138.67M | -88.5% | |
| 5Y | -$83.83M | -211.8% | |
| All | $343.00K | >-9999.0% |
Quarterly Operating Profit Lows
| Period | Low | Date | Current |
|---|---|---|---|
| 1Y | -$261.35M | at low | |
| 3Y | -$261.35M | at low | |
| 5Y | -$261.35M | at low | |
| All | -$261.35M | at low |
Quarterly Operating Profit History
FAQ
What is the current quarterly operating profit of INSM?
As of today, INSM quarterly operating profit is -$261.35M
What is INSM quarterly operating profit most recent change?
INSM quarterly operating profit was down -2.94% on September 30, 2025
What is 1-year change in INSM quarterly operating profit?
INSM quarterly operating profit is down -31.50% year-over-year
How far is INSM quarterly operating profit from its all-time high?
INSM quarterly operating profit is currently -76295.92% below its historical high of $343.00K set on December 31, 2009
How does INSM quarterly operating profit rank versus sector peers?
INSM quarterly operating profit is higher than 0.27% of companies in Healthcare sector
When is INSM next earnings release?
The next earnings release for INSM is on
TTM Operating Profit
-$990.28M$62.61M-6.75%
Summary
- Current Value
- As of today, INSM TTM operating profit is -$990.28M, down -6.75% on
- Historical Performance
- INSM TTM operating profit is down -40.68% year-over-year, and down -133.07% over the past 3 years
- All-Time High Comparison
- INSM TTM operating profit is currently -69687.32% below its historical high of -$1.42M set on
- 3-Year Low Comparison
- INSM TTM operating profit is at its 3-year low
- Sector Comparison
- INSM TTM operating profit is higher than 0.36% of companies in Healthcare sector
Performance
| Metric | Date | Value | 3M | 1Y | 3Y | 5Y |
|---|---|---|---|---|---|---|
| TTM Operating Profit | -$990.28M | -6.8% | -40.7% | -133.1% | -354.7% | |
| Annual Operating Profit | -$786.57M | – | -15.5% | -113.9% | -234.4% | |
| Quarterly Operating Profit | -$261.35M | -2.9% | -31.5% | -113.4% | -364.9% | |
| Price | $177.12 | +15.9% | +153.2% | +786.5% | +432.1% | |
| PE Ratio | - | – | – | – | – | |
| TTM Revenue | $447.02M | +12.3% | +30.3% | +84.6% | +165.0% | |
| TTM EPS | -$6.18 | -8.4% | -11.3% | -70.1% | -137.9% | |
| TTM Gross Profit | $336.83M | +13.7% | +29.6% | +85.3% | +167.3% | |
| Quarterly Operating Expenses | $372.79M | +12.3% | +38.2% | +112.5% | +323.6% |
TTM Operating Profit Highs
| Period | High | Date | Current |
|---|---|---|---|
| 1Y | -$786.57M | N/A | -25.9% |
| 3Y | -$478.12M | N/A | -107.1% |
| 5Y | -$265.23M | N/A | -273.4% |
| All | -$1.42M | >-9999.0% |
TTM Operating Profit Lows
| Period | Low | Date | Current |
|---|---|---|---|
| 1Y | -$990.28M | at low | |
| 3Y | -$990.28M | at low | |
| 5Y | -$990.28M | at low | |
| All | -$990.28M | at low |
TTM Operating Profit History
FAQ
What is the current TTM operating profit of INSM?
As of today, INSM TTM operating profit is -$990.28M
What is INSM TTM operating profit most recent change?
INSM TTM operating profit was down -6.75% on September 30, 2025
What is 1-year change in INSM TTM operating profit?
INSM TTM operating profit is down -40.68% year-over-year
How far is INSM TTM operating profit from its all-time high?
INSM TTM operating profit is currently -69687.32% below its historical high of -$1.42M set on September 30, 2010
How does INSM TTM operating profit rank versus sector peers?
INSM TTM operating profit is higher than 0.36% of companies in Healthcare sector
When is INSM next earnings release?
The next earnings release for INSM is on
Operating Profit Formula
Operating Profit = Gross Profit −
Data Sources & References
- INSM Official Website www.insmed.com
- Most Recent Quarterly Report (10-Q) www.sec.gov/Archives/edgar/data/1104506/000110450625000053/0001104506-25-000053-index.htm
- Most Recent Annual Report (10-K) www.sec.gov/Archives/edgar/data/1104506/000110450625000009/0001104506-25-000009-index.htm
- INSM Profile on Yahoo Finance finance.yahoo.com/quote/INSM
- INSM Profile on NASDAQ.com www.nasdaq.com/market-activity/stocks/insm