Annual Operating Profit
-$443.59M$121.13M+21.45%
Summary
- Current Value
- As of today, GH annual operating profit is -$443.59M, up +21.45% on
- Historical Performance
- GH annual operating profit is down -7.93% over the past 3 years, and down -438.53% over the past 5 years
- All-Time High Comparison
- GH annual operating profit is currently -911.69% below its historical high of -$43.85M set on
- 3-Year Low Comparison
- GH annual operating profit is +21.45% above its 3-year low of -$564.73M reached on
- Sector Comparison
- GH annual operating profit is higher than 2.29% of companies in Healthcare sector
Operating Profit Chart
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Series
SUGGESTED SERIES
Performance
| Metric | Date | Value | 1Y | 3Y | 5Y | 15Y |
|---|---|---|---|---|---|---|
| Annual Operating Profit | -$443.59M | +21.4% | -7.9% | -438.5% | -911.7% | |
| Quarterly Operating Profit | -$98.99M | +15.6% | +31.4% | -33.3% | -560.8% | |
| TTM Operating Profit | -$442.41M | +14.1% | +10.3% | -145.7% | -2853.3% | |
| Price | $108.74 | +197.2% | +319.0% | -23.9% | – | |
| PE Ratio | - | – | – | – | – | |
| Annual Revenue | $739.02M | +31.0% | +97.8% | +244.7% | +2826.9% | |
| Annual EPS | -$3.56 | +17.0% | +11.2% | -325.8% | -558.2% | |
| Annual Gross Profit | $449.22M | +33.3% | +79.2% | +212.7% | +10000.0% | |
| Annual Operating Expenses | $892.81M | -1.0% | +34.9% | +295.0% | +1800.7% |
Operating Profit Highs
| Period | High | Date | Current |
|---|---|---|---|
| 3Y | -$443.59M | at high | |
| 5Y | -$254.95M | N/A | -74.0% |
| All | -$43.85M | -911.7% |
Operating Profit Lows
| Period | Low | Date | Current |
|---|---|---|---|
| 3Y | -$564.73M | +21.4% | |
| 5Y | -$564.73M | +21.4% | |
| All | -$564.73M | +21.4% |
Operating Profit History
| Year | Value | Change |
|---|---|---|
| -$443.59M | +21.4% | |
| -$564.73M | -3.7% | |
| -$544.38M | -32.5% | |
| -$411.00M | -61.2% | |
| -$254.95M | -209.5% |
| Year | Value | Change |
|---|---|---|
| -$82.37M | +11.4% | |
| -$92.94M | -21.3% | |
| -$76.61M | -74.7% | |
| -$43.85M | - |
FAQ
What is the current annual operating profit of GH?
As of today, GH annual operating profit is -$443.59M
What is 1-year change in GH annual operating profit?
GH annual operating profit is up +21.45% year-over-year
What is 3-year change in GH annual operating profit?
GH annual operating profit is down -7.93% over the past 3 years
How far is GH annual operating profit from its all-time high?
GH annual operating profit is currently -911.69% below its historical high of -$43.85M set on December 31, 2016
How does GH annual operating profit rank versus sector peers?
GH annual operating profit is higher than 2.29% of companies in Healthcare sector
When is GH next annual earnings release?
The next annual earnings release for GH is on
Quarterly Operating Profit
-$98.99M$7.42M+6.98%
Summary
- Current Value
- As of today, GH quarterly operating profit is -$98.99M, up +6.98% on
- Historical Performance
- GH quarterly operating profit is up +15.63% year-over-year, and up +31.35% over the past 3 years
- All-Time High Comparison
- GH quarterly operating profit is currently -560.81% below its historical high of -$14.98M set on
- 3-Year Low Comparison
- GH quarterly operating profit is +49.80% above its 3-year low of -$197.18M reached on
- Sector Comparison
- GH quarterly operating profit is higher than 3.39% of companies in Healthcare sector
Performance
| Metric | Date | Value | 3M | 1Y | 3Y | 5Y |
|---|---|---|---|---|---|---|
| Quarterly Operating Profit | -$98.99M | +7.0% | +15.6% | +31.4% | -33.3% | |
| Annual Operating Profit | -$443.59M | – | +21.4% | -7.9% | -438.5% | |
| TTM Operating Profit | -$442.41M | +4.0% | +14.1% | +10.3% | -145.7% | |
| Price | $108.74 | +66.5% | +197.2% | +319.0% | -23.9% | |
| PE Ratio | - | – | – | – | – | |
| Quarterly Revenue | $265.20M | +14.3% | +38.5% | +125.9% | +255.6% | |
| Quarterly EPS | -$0.74 | +7.7% | +15.2% | +53.1% | +4.8% | |
| Quarterly Gross Profit | $171.61M | +13.7% | +46.7% | +123.1% | +221.5% | |
| Quarterly Operating Expenses | $270.60M | +5.2% | +15.5% | +22.4% | +112.0% |
Quarterly Operating Profit Highs
| Period | High | Date | Current |
|---|---|---|---|
| 1Y | -$98.99M | at high | |
| 3Y | -$98.99M | at high | |
| 5Y | -$91.17M | N/A | -8.6% |
| All | -$14.98M | -560.8% |
Quarterly Operating Profit Lows
| Period | Low | Date | Current |
|---|---|---|---|
| 1Y | -$125.97M | N/A | +21.4% |
| 3Y | -$197.18M | +49.8% | |
| 5Y | -$197.18M | +49.8% | |
| All | -$197.18M | +49.8% |
Quarterly Operating Profit History
FAQ
What is the current quarterly operating profit of GH?
As of today, GH quarterly operating profit is -$98.99M
What is GH quarterly operating profit most recent change?
GH quarterly operating profit was up +6.98% on September 30, 2025
What is 1-year change in GH quarterly operating profit?
GH quarterly operating profit is up +15.63% year-over-year
How far is GH quarterly operating profit from its all-time high?
GH quarterly operating profit is currently -560.81% below its historical high of -$14.98M set on March 1, 2017
How does GH quarterly operating profit rank versus sector peers?
GH quarterly operating profit is higher than 3.39% of companies in Healthcare sector
When is GH next earnings release?
The next earnings release for GH is on
TTM Operating Profit
-$442.41M$18.34M+3.98%
Summary
- Current Value
- As of today, GH TTM operating profit is -$442.41M, up +3.98% on
- Historical Performance
- GH TTM operating profit is up +14.06% year-over-year, and up +10.30% over the past 3 years
- All-Time High Comparison
- GH TTM operating profit is currently -2853.32% below its historical high of -$14.98M set on
- 3-Year Low Comparison
- GH TTM operating profit is +21.39% above its 3-year low of -$562.80M reached on
- Sector Comparison
- GH TTM operating profit is higher than 2.50% of companies in Healthcare sector
Performance
| Metric | Date | Value | 3M | 1Y | 3Y | 5Y |
|---|---|---|---|---|---|---|
| TTM Operating Profit | -$442.41M | +4.0% | +14.1% | +10.3% | -145.7% | |
| Annual Operating Profit | -$443.59M | – | +21.4% | -7.9% | -438.5% | |
| Quarterly Operating Profit | -$98.99M | +7.0% | +15.6% | +31.4% | -33.3% | |
| Price | $108.74 | +66.5% | +197.2% | +319.0% | -23.9% | |
| PE Ratio | - | – | – | – | – | |
| TTM Revenue | $902.57M | +8.9% | +30.4% | +109.5% | +232.7% | |
| TTM EPS | -$3.21 | +4.0% | +24.2% | +45.9% | -68.1% | |
| TTM Gross Profit | $575.46M | +10.5% | +38.0% | +100.2% | +210.5% | |
| Quarterly Operating Expenses | $270.60M | +5.2% | +15.5% | +22.4% | +112.0% |
TTM Operating Profit Highs
| Period | High | Date | Current |
|---|---|---|---|
| 1Y | -$442.41M | at high | |
| 3Y | -$442.41M | at high | |
| 5Y | -$245.25M | N/A | -80.4% |
| All | -$14.98M | -2853.3% |
TTM Operating Profit Lows
| Period | Low | Date | Current |
|---|---|---|---|
| 1Y | -$460.75M | +4.0% | |
| 3Y | -$562.80M | +21.4% | |
| 5Y | -$562.80M | +21.4% | |
| All | -$562.80M | +21.4% |
TTM Operating Profit History
FAQ
What is the current TTM operating profit of GH?
As of today, GH TTM operating profit is -$442.41M
What is GH TTM operating profit most recent change?
GH TTM operating profit was up +3.98% on September 30, 2025
What is 1-year change in GH TTM operating profit?
GH TTM operating profit is up +14.06% year-over-year
How far is GH TTM operating profit from its all-time high?
GH TTM operating profit is currently -2853.32% below its historical high of -$14.98M set on March 1, 2017
How does GH TTM operating profit rank versus sector peers?
GH TTM operating profit is higher than 2.50% of companies in Healthcare sector
When is GH next earnings release?
The next earnings release for GH is on
Operating Profit Formula
Operating Profit = Gross Profit −
Data Sources & References
- GH Official Website guardanthealth.com
- Most Recent Quarterly Report (10-Q) www.sec.gov/Archives/edgar/data/1576280/000157628025000277/0001576280-25-000277-index.htm
- Most Recent Annual Report (10-K) www.sec.gov/Archives/edgar/data/1576280/000157628025000044/0001576280-25-000044-index.htm
- GH Profile on Yahoo Finance finance.yahoo.com/quote/GH
- GH Profile on NASDAQ.com www.nasdaq.com/market-activity/stocks/gh