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Silo Pharma Announces Positive Initial Pharmacokinetic, Safety, and Tolerability Study of SP-26 for Chronic Pain and Fibromyalgia
Silo Pharma Announces Positive Initial Pharmacokinetic, Safety, and Tolerability Study of SP-26 for Chronic Pain and Fibromyalgia
Silo Pharma Announces Positive Initial Pharmacokinetic, Safety, and Tolerability Study of SP-26 for Chronic Pain and Fibromyalgia
SILO
globenewswire.comFebruary 11, 2025

No serious side effects or discomfort observed Final safety and absorption data expected in March 2025 SARASOTA, FL, Feb. 11, 2025 (GLOBE NEWSWIRE) -- Silo Pharma, Inc. (Nasdaq: SILO) (“Silo” or the “Company”), a developmental stage biopharmaceutical company focused on novel therapeutics and drug delivery systems, today announced a positive update from an ongoing study evaluating the pharmacokinetics, safety and tolerability of its novel SP-26 ketamine extended-release rods when implanted subcutaneously. The SP-26 implant is a novel self-administered, non-opioid therapeutic intended for the treatment of chronic pain and fibromyalgia.

LIBERTY LATIN AMERICA'S C&W CREDIT SILO COMPLETES REFINANCING PROGRAM; ISSUES NEW $755 MILLION SENIOR NOTES DUE 2033
LIBERTY LATIN AMERICA'S C&W CREDIT SILO COMPLETES REFINANCING PROGRAM; ISSUES NEW $755 MILLION SENIOR NOTES DUE 2033
LIBERTY LATIN AMERICA'S C&W CREDIT SILO COMPLETES REFINANCING PROGRAM; ISSUES NEW $755 MILLION SENIOR NOTES DUE 2033
SILO
businesswire.comFebruary 10, 2025

DENVER, Colorado--(BUSINESS WIRE)--Liberty Latin America's (“LLA” or the “Company”) largest credit silo, Cable & Wireless (“C&W”), has priced new $755 million senior notes due 2033 with a 9.0% coupon at par. Net proceeds from the issuance will be used to fully redeem C&W's $735 million senior notes due 2027. This notes issuance is expected to close on February 11, 2025. Chris Noyes, Liberty Latin America's CFO, said, “This transaction completes our near-term refinancing objectives f.

LIBERTY LATIN AMERICA'S C&W CREDIT SILO PRICES NEW $1.5 BILLION TERM LOAN DUE 2032
LIBERTY LATIN AMERICA'S C&W CREDIT SILO PRICES NEW $1.5 BILLION TERM LOAN DUE 2032
LIBERTY LATIN AMERICA'S C&W CREDIT SILO PRICES NEW $1.5 BILLION TERM LOAN DUE 2032
SILO
businesswire.comFebruary 4, 2025

DENVER, Colorado--(BUSINESS WIRE)--Liberty Latin America's (“LLA” or the “Company”) largest credit silo, Cable & Wireless (“C&W”), priced a new $1.5 billion term loan at the end of January 2025. This term loan matures in 2032, bears interest at a rate of SOFR + 3.25%, and the net proceeds will be used to repay a $1.5 billion term loan maturing in 2028. This transaction is expected to close on February 18, 2025. Chris Noyes, Liberty Latin America's CFO, said, “Combined with the $1.0 bill.

Silo Pharma Issues Letter to Shareholders Detailing Development Progress and Potential for Lead Assets Targeting PTSD and Chronic Pain
Silo Pharma Issues Letter to Shareholders Detailing Development Progress and Potential for Lead Assets Targeting PTSD and Chronic Pain
Silo Pharma Issues Letter to Shareholders Detailing Development Progress and Potential for Lead Assets Targeting PTSD and Chronic Pain
SILO
globenewswire.comJanuary 2, 2025

SARASOTA, FL, Jan. 02, 2025 (GLOBE NEWSWIRE) -- Silo Pharma, Inc. (Nasdaq: SILO) (“Silo” “we,” “us,” “our,” or the “Company”), a developmental stage biopharmaceutical company focused on developing novel formulations and drug delivery systems for traditional therapeutics and psychedelic treatments, today issued a letter to shareholders highlighting the Company's progress and potential for its lead assets SPC-15 and SP-26 as treatments for mental health and chronic pain management, respectively. The letter, in its entirety, is reprinted below.

Silo Pharma Initiates Pharmacokinetic and Tolerability Study for SP-26 Targeting Chronic Pain and Fibromyalgia
Silo Pharma Initiates Pharmacokinetic and Tolerability Study for SP-26 Targeting Chronic Pain and Fibromyalgia
Silo Pharma Initiates Pharmacokinetic and Tolerability Study for SP-26 Targeting Chronic Pain and Fibromyalgia
SILO
globenewswire.comDecember 18, 2024

Key preclinical milestone for novel, non-opioid extended-release pain therapeutic   SARASOTA, FL, Dec. 18, 2024 (GLOBE NEWSWIRE) -- Silo Pharma, Inc. (Nasdaq: SILO) (“Silo” or the “Company”), a developmental stage biopharmaceutical company focused on developing novel formulations and drug delivery systems for traditional therapeutics and psychedelic treatments, today announced the initiation of a pharmacokinetic (PK) and tolerability study in partnership with its contract research organization (CRO), AmplifyBio. The study is designed to assess the pharmacokinetics of Silo's dissolvable ketamine-based injectable implant, SP-26, in a minipig model.

Silo Pharma Reports Positive Results in Sterilization and Dissolution Testing of SP-26 Ketamine Implant
Silo Pharma Reports Positive Results in Sterilization and Dissolution Testing of SP-26 Ketamine Implant
Silo Pharma Reports Positive Results in Sterilization and Dissolution Testing of SP-26 Ketamine Implant
SILO
globenewswire.comOctober 31, 2024

The implant demonstrates stability and consistent drug release, supporting further analytical testing and development SARASOTA, FL, Oct. 31, 2024 (GLOBE NEWSWIRE) -- Silo Pharma, Inc. (Nasdaq: SILO) (“Silo” or the “Company”), a developmental stage biopharmaceutical company focused on developing novel formulations and drug delivery systems for traditional therapeutics and psychedelic treatments, today announced promising results from recent sterilization and dissolution tests of its SP-26 ketamine-loaded implant for fibromyalgia and chronic pain. These tests were conducted under the Company's current development agreement with Sever Pharma Solutions.

Silo Pharma Expands Development Agreement with Sever Pharma for Novel Ketamine Implant Therapeutic
Silo Pharma Expands Development Agreement with Sever Pharma for Novel Ketamine Implant Therapeutic
Silo Pharma Expands Development Agreement with Sever Pharma for Novel Ketamine Implant Therapeutic
SILO
globenewswire.comAugust 14, 2024

SP-26 dissolvable ketamine-based injectable implant targets chronic pain and fibromyalgia Sever Pharma to scale-up extrusion processes and continue analytical testing for novel non-opioid treatment SARASOTA, FL, Aug. 14, 2024 (GLOBE NEWSWIRE) -- Silo Pharma, Inc. (Nasdaq: SILO) (“Silo” or the “Company”), a developmental stage biopharmaceutical company focused on developing novel formulations and drug delivery systems for traditional therapeutics and psychedelic treatments, today announced a new agreement with Sever Pharma Solutions for scale-up extrusion of the Company's SP-26 ketamine-loaded implant therapeutic targeting fibromyalgia and chronic pain. In addition, Sever Pharma Solutions will continue with analytical testing of the ketamine hydrochloride (ketamine HCL) polymer implants using the optimal time-released, dose-controlled formulation previously selected by Silo for continuing pre-clinical studies.

Why Is Silo Pharma (SILO) Stock Up 60% Today?
Why Is Silo Pharma (SILO) Stock Up 60% Today?
Why Is Silo Pharma (SILO) Stock Up 60% Today?
SILO
investorplace.comJuly 18, 2024

Developmental-stage pharmaceutical firm Silo Pharma (NASDAQ: SILO ) — which specializes in both traditional and psychedelic therapeutics to address stress-induced psychiatric disorders — saw its shares rise dramatically on Thursday. Earlier this morning, the company announced a partnership to develop an intranasal drug to address post-traumatic stress disorder (PTSD).

Why Is Silo Pharma (SILO) Stock Up 123% Today?
Why Is Silo Pharma (SILO) Stock Up 123% Today?
Why Is Silo Pharma (SILO) Stock Up 123% Today?
SILO
investorplace.comJuly 16, 2024

Silo Pharma (NASDAQ: SILO ) stock is rocketing higher on Tuesday after the developmental stage biopharmaceutical company secured a new global license. This license covers the development, manufacturing, and commercialization of its Alzheimer's drug SPC-14.

Silo Pharma Announces Successful Production of its SP-26 Ketamine Implant for Fibromyalgia
Silo Pharma Announces Successful Production of its SP-26 Ketamine Implant for Fibromyalgia
Silo Pharma Announces Successful Production of its SP-26 Ketamine Implant for Fibromyalgia
SILO
globenewswire.comJune 7, 2024

Analytical testing has confirmed optimal formulation for upcoming studies SARASOTA, FL, June 07, 2024 (GLOBE NEWSWIRE) -- Silo Pharma, Inc. (Nasdaq: SILO) (“Silo” or the “Company”), a developmental stage biopharmaceutical company focused on developing novel formulations and drug delivery systems for traditional therapeutics and psychedelic treatments, today announced a successful series of development activities for the Company's SP-26 ketamine implant therapeutic targeting fibromyalgia and chronic pain. An ongoing pre-clinical research study of SP-26 is underway involving analytical testing services and small batch proof-of-concept extrusion trials for the ketamine hydrochloride (ketamine HCL) implants at 20% and 40% drug load.

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